Phase 2 Stomach Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People between 18 and 80 years old who are scheduled to have surgery for stomach cancer
• People whose stomach cancer has been confirmed by a laboratory tissue test (pathology), regardless of the specific type of stomach cancer
• People whose cancer has been assessed by a CT scan as being at stage I, II, or III (meaning it has not spread far), and who are having either keyhole (laparoscopic) or open stomach cancer surgery
• People whose blood protein (albumin) level is at least 30g/L and whose nutrition screening score (NRS-2002) is 2 or lower, indicating nutritional levels are within an acceptable range before surgery
• People having any type of radical stomach cancer surgery, whether removing part or all of the stomach
• People who have given their written agreement to take part in the study
• People whose overall physical fitness for surgery is rated as ASA Class I, II, or III (a standard medical rating scale)
• People whose general ability to carry out daily activities is rated at 2 or below on the ECOG scale (a standard scale used to measure how cancer affects daily living)

Who may not be able to join:

• People who have an active infection or acute complication before surgery, such as pneumonia, urinary tract infection, gastrointestinal bleeding, a perforation, or a bowel blockage
• People with a weakened immune system, including those who have been taking immune-suppressing medicines (such as steroids) long-term, people who have had an organ transplant, or people diagnosed with HIV
• People with serious underlying health conditions, such as severe liver disease (Child-Pugh Class B or C), kidney problems with creatinine levels above 133 umol/L, severe heart failure (NYHA Class III or above), or severe lung problems where oxygen levels in the blood are too low (PaO2 at or below 60mmHg) (confirm with trial site)
• People who have a known allergy to albumin (a blood protein product)
• People who lose more than 500ml of blood during surgery
• People whose haemoglobin (a measure of red blood cells) is below 70g/L before surgery
• People who have received radiation therapy (radiotherapy) before surgery as part of their cancer treatment
• People who need additional organs removed at the same time as their stomach surgery
• People in whom cancer is found to have spread to distant parts of the body during surgery, or where complete removal of the cancer is not possible

Reasons a person may be withdrawn from the trial after joining:

• If a serious allergic reaction to the albumin infusion occurs during the trial, such as severe shock, airway swelling, or dangerously low blood pressure
• If a participant decides at any point that they no longer wish to continue taking part, their wishes will be respected and their participation will end

Important: Always verify eligibility with the trial site directly before applying.