Phase 1 Stomach Cancer Trial, Recruiting NCT07165132 Sponsor: RayzeBio, Inc. Condition: Stomach Cancer
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Phase 1 Stomach Cancer Trial, Recruiting

NCT07165132
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are at least 18 years old at the time of signing the study consent form
  • People who have a tissue-confirmed diagnosis of a well-differentiated (slow-growing) neuroendocrine tumour (NET) that has spread or cannot be surgically removed — this applies across various tumour locations, including the gut, pancreas, lungs, thyroid, breast, urogenital system, and adrenal glands (for the initial dose-testing phase)
  • People with a confirmed well-differentiated NET originating in the gut or pancreas that has spread or cannot be surgically removed (for one specific expansion group)
  • People with a confirmed well-differentiated NET from sites other than the gut or pancreas, or a confirmed meningioma (a type of brain/skull tumour), that has spread or cannot be surgically removed — where the tumour is known to frequently carry a specific protein called SSTR (for another expansion group)
  • People whose tumour shows positive results on a specific type of scan that detects the SSTR protein
  • People whose kidneys, blood, and liver are functioning at an adequate level

Who may not be able to join:

  • People who have previously received a type of treatment called radioligand or radiopeptide therapy, including a treatment known as Lu-177
  • People who have previously had a solid organ transplant or bone marrow transplant
  • People who use steroid medication on an ongoing, long-term basis taken throughout the whole body (not just topically)
  • People with significant heart or cardiovascular disease
  • People with high blood pressure that has not responded to treatment
  • People with diabetes that is not well controlled
  • People with a prior history of liver cirrhosis (severe liver scarring)
  • People who have HIV, hepatitis B, or a currently active hepatitis C infection

Important: Always verify eligibility with the trial site directly before applying. Additional criteria may also apply and will be assessed by the study site.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Ye Yuan, MD, RayzeBio, Inc.

Phone: +1 619 657 0057

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
RayzeBio, Inc.
Registry
ClinicalTrials.gov
Start date
3 December 2025
Est. completion
1 February 2027

Where this trial is recruiting

🇨🇦 Canada 🇺🇸 United States

Primary endpoints

Dose Escalation; Dose Expansion

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov