Type 2 Diabetes Trial, Recruiting NCT07272460 Sponsor: Mount Sinai Hospital, Canada Condition: Type 2 Diabetes
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Type 2 Diabetes Trial, Recruiting

NCT07272460
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been previously diagnosed with a BMI of 25 or higher and have had type 2 diabetes within the last 10 years
  • You are between 18 and 75 years old
  • Your weight has been fairly stable for the past 12 weeks, meaning it has changed by less than 5% (based on what you report yourself)
  • You manage your diabetes through lifestyle changes only, or with one or more of the following medications: metformin, a DPP-4 inhibitor, or an SGLT2 inhibitor (confirm with trial site if unsure which type of medication you take)
  • You are able to read and understand English

Who may not be able to join:

  • You currently take insulin, GLP-1 receptor agonists (such as semaglutide or liraglutide), or sulfonylureas for your diabetes (confirm with trial site if unsure which type of medication you take)
  • You are currently taking any medication specifically prescribed to help with weight loss
  • You have previously had weight-loss surgery, such as a gastric bypass or gastric band
  • You have any history of an eating disorder
  • You are currently pregnant or breastfeeding
  • You have significant kidney problems, specifically a low kidney function score as measured by a blood test (confirm with trial site)
  • You have a moderate to severe heart failure condition (confirm with trial site)
  • You have a significant liver disease, such as jaundice, chronic hepatitis, or a previous liver transplant, or your liver function blood tests are notably abnormal
  • You have been treated for cancer (with the exception of a common type of minor skin cancer) in the past 5 years, including treatment with chemotherapy, surgery, or radiation
  • There is any other reason the research team thinks you may have difficulty following the study as required
  • You are currently taking part in another research study related to diabetes or metabolic health

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Mount Sinai Hospital, Canada
Registry
ClinicalTrials.gov
Start date
1 February 2026
Est. completion
30 March 2029

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Differences in baseline-adjusted Insulin-Secretion-Sensitivity Index-2 (ISSI-2) between the study groups.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov