Phase 3 Type 2 Diabetes Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older at the time of signing the consent form
- People with a BMI of 28 or above, OR a BMI of 24 or above along with at least one weight-related health condition already diagnosed (such as high blood pressure, abnormal cholesterol levels, pre-diabetes, obstructive sleep apnea, fatty liver, or joint pain caused by weight)
- People whose body weight has changed by no more than 5% in the 90 days before their screening visit (based on self-reporting)
- People who are able to understand the study procedures, are willing to follow the trial requirements throughout, and are willing to sign the consent form
Who may not be able to join:
- People who have been diagnosed with type 1 or type 2 diabetes
- People whose blood sugar levels (HbA1c or fasting glucose) are above certain thresholds at the first study visit (confirm with trial site)
- People whose excess weight is caused by a hormonal disorder (such as Cushing's syndrome) or by a medication
- People who have used certain diabetes or weight-related injectable medications (GLP-1 or related drug classes) in the 3 months before screening
- People who have used blood sugar-lowering medications in the 3 months before screening
- People with a personal or family history of a specific type of thyroid cancer or a condition called multiple endocrine neoplasia type 2A or 2B
- People with a history of pancreatitis (either short-term or long-term) or active gallbladder disease (unless the gallbladder has been surgically removed)
- People who score 15 or higher on a depression screening questionnaire (called the PHQ) at the screening or enrolment visit
- People with a history of moderate to severe depression, or a history of serious mental illness
- People with high blood pressure that is not well controlled (specifically, readings at or above 160/100 mmHg before screening)
- People who have had a cancer diagnosis in the past 5 years, with the exception of a type of skin cancer (basal cell carcinoma) that has been fully treated and cured
- People who have had a serious heart or stroke-related event in the past 6 months
- People with a current or recent history of alcohol or drug misuse
- People who may be allergic to any ingredient in the study drug or related medications
- Women who are pregnant or breastfeeding, or people of childbearing potential who are not willing to use contraception throughout the study
- People who, in the opinion of the trial doctor, have any other factor that might affect the safety or results of the study
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Xiaoying Li, Shanghai Zhongshan Hospital
Phone: +86 0571-89908523
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
primary outcome; Co-primary outcome
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.