Phase 2 Primary Biliary Cholangitis Trial, Not Yet Recruiting (NCT07341282)

Phase 2 Primary Biliary Cholangitis Trial, Not Yet Recruiting NCT07341282 Sponsor: McMaster University Condition: Primary Biliary Cholangitis

Printed from Voxsanity (voxsanity.com.au) — NCT07341282 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Primary Biliary Cholangitis

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are 18 years of age or older
You have been formally diagnosed with both ulcerative colitis (a type of inflammatory bowel disease) and a liver condition called primary sclerosing cholangitis (PSC)
Your ulcerative colitis is currently rated as moderate to severe, based on specific scores measured by your doctor and a camera examination of your bowel
You are willing and able to give your written agreement to take part in the trial

Who may not be able to join:

You have been diagnosed with Crohn's disease or a similar condition where the type of bowel disease is uncertain
Your ulcerative colitis is severely flaring up in a way that may require urgent surgery
You have taken antibiotics or probiotic supplements in the last 4 weeks (this applies to a specific part of the study involving gut bacteria)
Your liver disease is at an advanced or poorly controlled stage (confirm with trial site)
Your kidneys are not working well enough, based on a specific blood test result (confirm with trial site)
You currently have an active infection that is not being treated
You are pregnant or currently breastfeeding
You have previously had an allergic reaction or bad reaction to a medicine called Vancomycin
You have a history of hearing loss or are currently experiencing any hearing problems

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 28 July 2026

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Neeraj Narula, MD, McMaster University

Phone: 905-521-2100

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07341282

Sponsor: McMaster University

Phase: Phase 2

Status: Not Yet Recruiting

Condition: Primary Biliary Cholangitis

Trial contact: 905-521-2100

More information: https://clinicaltrials.gov/study/NCT07341282

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are 18 years of age or older
You have been formally diagnosed with both ulcerative colitis (a type of inflammatory bowel disease) and a liver condition called primary sclerosing cholangitis (PSC)
Your ulcerative colitis is currently rated as moderate to severe, based on specific scores measured by your doctor and a camera examination of your bowel
You are willing and able to give your written agreement to take part in the trial

Who may not be able to join:

You have been diagnosed with Crohn's disease or a similar condition where the type of bowel disease is uncertain
Your ulcerative colitis is severely flaring up in a way that may require urgent surgery
You have taken antibiotics or probiotic supplements in the last 4 weeks (this applies to a specific part of the study involving gut bacteria)
Your liver disease is at an advanced or poorly controlled stage (confirm with trial site)
Your kidneys are not working well enough, based on a specific blood test result (confirm with trial site)
You currently have an active infection that is not being treated
You are pregnant or currently breastfeeding
You have previously had an allergic reaction or bad reaction to a medicine called Vancomycin
You have a history of hearing loss or are currently experiencing any hearing problems

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 28 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Not Yet Recruiting

Phase

Phase 2

Sponsor

McMaster University

Registry

ClinicalTrials.gov

Start date

1 January 2026

Est. completion

1 December 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Recruitment rate; Retention rate; Treatment adherence; Protocol compliance with study procedures

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov