Epilepsy Trial, Recruiting (NCT07399327)

Epilepsy Trial, Recruiting NCT07399327 Sponsor: Assistance Publique Hopitaux De Marseille Condition: Epilepsy

Printed from Voxsanity (voxsanity.com.au) — NCT07399327 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Epilepsy

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

The patient, their parents, or their legal representative has agreed to take part and signed a consent form
The patient is aged 12 or older and has focal epilepsy that has not responded to medication
The patient has already had a standard pre-surgical assessment, including medical history, a scalp video-EEG recording, and a 3T MRI brain scan
A type of brain mapping procedure called SEEG (stereo-EEG) has already been recommended for the patient as part of their pre-surgical evaluation
The patient is able to understand, speak, and write in French
The patient is able to follow the steps and procedures involved in the study
The patient is covered by a health insurance plan

Who may not be able to join:

People whose epilepsy surgery does not require a SEEG procedure
People who cannot safely have a 3T or 7T brain MRI — for example, those with a cardiac pacemaker, metal objects in the body, non-removable implanted electronic devices, claustrophobia, an inability to lie flat, a Vagus Nerve Stimulator (VNS) or Deep Brain Stimulator (DBS), an intrauterine device (IUD), or a tattoo in the scan area that is less than 6 weeks old at the time of the MRI
People who cannot receive the contrast dye (gadolinium) used during MRI — for example, those with a history of allergic or severe reactions to gadolinium or related substances, serious kidney problems (confirm with trial site for specific kidney function threshold), people on dialysis, or those with a history of kidney disease such as a transplant, a single kidney, or kidney cancer
People in certain protected legal categories under French public health law — including pregnant or breastfeeding women, people deprived of liberty by a court decision, people in situations of social vulnerability, or adults who are unable to give their own consent
People who are currently taking part in another clinical study that has an exclusion period still in effect

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 23 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 0491384990

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07399327

Sponsor: Assistance Publique Hopitaux De Marseille

Phase: Not Applicable

Status: Recruiting

Condition: Epilepsy

Trial contact: 0491384990

More information: https://clinicaltrials.gov/study/NCT07399327

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

The patient, their parents, or their legal representative has agreed to take part and signed a consent form
The patient is aged 12 or older and has focal epilepsy that has not responded to medication
The patient has already had a standard pre-surgical assessment, including medical history, a scalp video-EEG recording, and a 3T MRI brain scan
A type of brain mapping procedure called SEEG (stereo-EEG) has already been recommended for the patient as part of their pre-surgical evaluation
The patient is able to understand, speak, and write in French
The patient is able to follow the steps and procedures involved in the study
The patient is covered by a health insurance plan

Who may not be able to join:

People whose epilepsy surgery does not require a SEEG procedure
People who cannot safely have a 3T or 7T brain MRI — for example, those with a cardiac pacemaker, metal objects in the body, non-removable implanted electronic devices, claustrophobia, an inability to lie flat, a Vagus Nerve Stimulator (VNS) or Deep Brain Stimulator (DBS), an intrauterine device (IUD), or a tattoo in the scan area that is less than 6 weeks old at the time of the MRI
People who cannot receive the contrast dye (gadolinium) used during MRI — for example, those with a history of allergic or severe reactions to gadolinium or related substances, serious kidney problems (confirm with trial site for specific kidney function threshold), people on dialysis, or those with a history of kidney disease such as a transplant, a single kidney, or kidney cancer
People in certain protected legal categories under French public health law — including pregnant or breastfeeding women, people deprived of liberty by a court decision, people in situations of social vulnerability, or adults who are unable to give their own consent
People who are currently taking part in another clinical study that has an exclusion period still in effect

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 23 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Assistance Publique Hopitaux De Marseille

Registry

ClinicalTrials.gov

Start date

19 June 2026

Est. completion

31 January 2029

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Relationship between changes in the MRI biomarker of BBB permeability (the transfer coefficient, Ki) and clinical response (responder vs non responder) at 3 months after RFTC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov