Phase 2 Stomach Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 79 years old who are able to give their consent to take part and are willing to follow all study requirements.
• People who are well enough to carry out basic daily activities, with a general health score within an acceptable range as assessed by a doctor (confirm with trial site).
• People who have been diagnosed with one of the following cancers, confirmed by a tissue or cell sample: colorectal cancer, stomach cancer, pancreatic cancer, invasive lobular breast cancer, or ovarian cancer (ovarian cancer may be suspected rather than fully confirmed).
• Women who could become pregnant must have a negative pregnancy test at two different points before receiving the study scan agent.
• Women who could become pregnant, and men who are sexually active with women who could become pregnant, must agree to use a reliable form of contraception for the whole duration of the study.
• For one group of participants (Cohort A): People with stage I to III cancer (or stage IV with five or fewer known areas where cancer has spread), with standard medical imaging done within 8 weeks of receiving the study scan agent.
• For another group of participants (Cohort B): People who have had standard imaging — including a contrast CT scan of the abdomen and pelvis — done within 8 weeks of entering the study and no later than 24 hours before receiving the study scan agent, with those images available to be shared with the study imaging team.
• Participants in Cohort B must also meet at least one of these situations: they have not yet had any cancer treatment and have at least stage IIB disease with a tissue sample available or a procedure planned within 42 days; or they have completed pre-surgery treatment with at least stage IIB disease at the start and have a procedure planned within 42 days; or they are suspected to have cancer that has come back after previous treatment.

Who may not be able to join:

• People who have received a radioactive substance within a certain period before the study scan (based on the type of substance used — confirm with trial site).
• People who have taken part in another clinical trial involving an experimental treatment within 2 weeks or 5 half-lives (whichever is longer) before receiving the study scan agent.
• People who have received another contrast agent — used for medical imaging — within 24 hours (for agents given through a vein) or 5 days (for agents taken by mouth) before the study scan.
• People with a history of severe claustrophobia or panic attacks in confined spaces.
• People with a known allergy or sensitivity to the study scan agent or any of its ingredients.
• People whose medical history or current health condition, in the doctor's judgment, could affect the reliability of the study results or the ability to complete the study.
• People with a known autoimmune or inflammatory condition that could make the scan images difficult to interpret, unless that condition is directly caused by the cancer being studied.
• People who have had radiation treatment to the abdomen, pelvis, or breast in the last 3 months.
• People who have implanted devices or materials in their body (such as stents or surgical clips) that could affect how the scan images are read, as judged by the doctor.
• People with significant kidney or liver problems.
• Women who are currently breastfeeding, unless they agree to pump and discard breast milk for at least 24 hours after receiving the study scan agent.
• For Cohort A only: People who have had any other type of cancer in the past, unless it was treated with the intention of curing it and they have been cancer-free for at least 5 years before joining (or at least 1 year for certain skin cancers or early-stage cervical cancer).

Important: Always verify eligibility with the trial site directly before applying.