Phase 2 Irritable Bowel Syndrome Trial, Recruiting NCT07481422 Sponsor: University of Rijeka Condition: Irritable Bowel Syndrome
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Phase 2 Irritable Bowel Syndrome Trial, Recruiting

NCT07481422
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 65 years old
  • Your IBS symptoms are rated as moderate to severe based on a standard symptom scoring test (a score above 175 on the IBS-Symptom Severity Score)
  • Your symptoms have not improved enough after trying common IBS treatments, such as certain antispasmodics, laxatives, anti-diarrhoea medication, certain antibiotics, antidepressants, or peppermint oil
  • You have already been tested and ruled out for coeliac disease (a gut condition triggered by gluten)
  • You are willing and able to give your written agreement to take part in the trial

Who may not be able to join:

  • You are currently pregnant or breastfeeding
  • You are a woman who could become pregnant but are unwilling to use an acceptable form of contraception during the trial
  • Your immune system is severely weakened — for example, if you have had an organ transplant, have a very low white blood cell count, are currently receiving cancer treatment, or are HIV positive
  • Your gut symptoms are caused by another diagnosed condition, such as inflammatory bowel disease (IBD) or a gut infection
  • You have a severe allergy to any of the ingredients in the capsules used in this trial
  • You have started a new antidepressant or had your antidepressant dose changed in the last 3 months
  • You have other serious health conditions, including significant neurological (brain/nerve) or psychiatric (mental health) conditions
  • You have taken antibiotics in the 3 months before joining the trial
  • You have previously had a faecal microbiota transplant (FMT) — a treatment involving donor stool — at any point in the past
  • You are unwilling to swallow the capsules used in this trial

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +385917293984

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Rijeka
Registry
ClinicalTrials.gov
Start date
15 March 2026
Est. completion
15 March 2027

Where this trial is recruiting

🇭🇷 Croatia

Primary endpoints

Efficacy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov