Type 2 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing and able to give their informed consent to take part in the study.
• People aged between 25 and 65 years (inclusive).
• People with a Body Mass Index (BMI) of 25 or above but below 50.
• People who have been formally diagnosed with Type 2 diabetes (T2DM) through recognised blood sugar or related tests.
• People whose blood sugar control measure (called HbA1c) was between 7.5% and 10.5% in a blood test taken within the last 3 months, where their doctor has recommended stronger treatment beyond tablets alone.
• People who are currently managing their Type 2 diabetes using a combination of oral (tablet) medications.
• People who have at least 12 months of experience managing their own diabetes through a recognised self-management program.

Who may not be able to join:

• People who are pregnant, breastfeeding, or planning to become pregnant in the next 9 to 12 months.
• People who may be considered vulnerable, including those with significant mental or physical disabilities, or those who are incarcerated.
• People who are currently enrolled in another research study, or who participated in one within the last 30 days.
• People who are currently using or have recently used injectable GLP-1 medications (a type of diabetes injection, separate from insulin).
• People whose overall health is rated at a high-risk level (classified as ASA level 4 or above) by medical assessment standards (confirm with trial site).
• People who cannot recognise the warning signs of low blood sugar (hypoglycaemia unawareness), or who have had more than one severe low blood sugar episode requiring help from another person in the past year.
• People whose test results suggest Type 1 diabetes or that their pancreas has stopped producing enough insulin, based on specific blood marker levels.
• People whose digestive tract has an unusual or complex shape or structure, identified through a previous camera examination (endoscopy) or medical imaging.
• People with a history of, or who are at high risk of, certain small bowel conditions including Crohn's disease, other inflammatory bowel disease, coeliac disease, bowel cancer surgery, or conditions involving blockages or abnormal connections in the intestines.
• People who have previously had surgery on their small bowel (such as having part of it removed).
• People with a currently active H. pylori stomach infection that has not been successfully treated and confirmed as cleared.
• People with a history of pancreatitis (inflammation of the pancreas), either long-term or sudden-onset.
• People with known active hepatitis or active liver disease.
• People with symptomatic gallstones, kidney stones, or a current gallbladder infection (acute cholecystitis).
• People with a history of blood clotting problems or certain upper digestive tract conditions such as ulcers, varicose veins in the stomach, narrowing of the digestive tract, or abnormal blood vessel growths in the intestines.
• People taking blood-thinning medications (such as warfarin) that cannot safely be paused for 7 days before and 14 days after the procedure.
• People taking certain anti-clotting medications (such as clopidogrel, prasugrel, or ticagrelor) that cannot safely be paused for 14 days before and after the procedure (low-dose aspirin is generally allowable — confirm with trial site).
• People with serious diabetes-related complications, including heart disease, high blood pressure, circulation problems in the legs, diabetic eye disease, or diabetes-related soft tissue infections.
• People currently taking steroid medications or drugs that affect how the gut moves (such as metoclopramide).
• People currently taking prescription or over-the-counter weight loss medications.
• People with persistent anaemia, defined as a low haemoglobin blood level below a certain threshold.
• People with significantly reduced kidney function, as measured by specific kidney filter rate tests (confirm with trial site for exact thresholds).
• People with an active, ongoing infection anywhere in the body.
• People on any ongoing blood-thinning therapy beyond low-dose aspirin.
• People who have received cancer chemotherapy in the past 9 months, have a history of radiation to the abdomen, or have had an active cancer diagnosis within the past 5 years.
• People with active illicit substance use or alcoholism.
• People with a known sensitivity or allergy to medications that may be used during the procedure, including sedatives, anaesthetics, or pain relief medications.
• People with any other blood test results that medical staff determine may be associated with poor outcomes (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.