Type 2 Diabetes Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are able to give written consent before any study procedures begin
- Women who have been post-menopausal for at least 1 year (meaning at least 1 year since their periods stopped)
- People aged between 40 and 75 years old
- People with suitable veins for blood draws or having a needle inserted into a vein
- People with a body mass index (BMI) between 25 and 38 (a measure of body weight relative to height)
- People whose eating habits have been stable, with no weight change of more than 5 kg in the past 3 months
- People who were diagnosed with type 2 diabetes at least 1.5 years before the study starts
- People whose type 2 diabetes is reasonably well managed, with an HbA1c blood sugar level below 8.5% (a measure of average blood sugar over recent months)
- People taking metformin alone, or metformin combined with certain other diabetes tablets (sulfonylureas and/or a DPP-IV inhibitor) at a stable dose for at least the past 3 months — people on a different diabetes medication called a GLP-1 agonist may be considered on a case-by-case basis (confirm with trial site)
- People with no signs of active diabetes-related complications such as active heart or circulation problems, active diabetic foot, nerve damage, or eye disease
- People with no signs of active liver or kidney problems
Who may not be able to join:
- People who have taken part in another clinical trial involving an experimental treatment in the past 3 months, or as decided by the trial doctor
- People who do moderate- to high-intensity sport or physical activity more than 3 times per week, or as decided by the trial doctor
- People who have been regularly exposed to cold conditions in the month before the study starts — for example, through daily cold baths, working in a cold environment, or regular cold-water swimming or cold showers
- People whose body weight has changed by more than 5 kg in the past 3 months
- People who drink more than 2 alcoholic drinks per day (for men) or more than 1 alcoholic drink per day (for women)
- People who smoke
- People who use insulin or a type of diabetes medication called an SGLT2 inhibitor
- People with heart failure or severe kidney or liver problems
- People with low haemoglobin levels in the blood (below certain thresholds for men and women — confirm specific values with trial site)
- People whose medical history, current medications, or fasting blood test results lead the trial doctor to advise that participation is not appropriate
- People who are pregnant
- People who have had a PET/CT scan as part of another study in the past year
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Denis P. Blondin, PhD, Université de Sherbrooke
Phone: 819-346-1110
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Whole-body insulin sensitivity measured as glucose infusion rate (GIR) in µmol/kg/min during the stable period of the low- and high-insulin phase of the clamp.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.