Irritable Bowel Syndrome Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have a medical reason to need both an upper digestive tract camera test (endoscopy) and a bowel camera test (colonoscopy)
• You have been diagnosed with a type of irritable bowel syndrome with diarrhea (IBS-D), confirmed using a specific set of international guidelines called Rome IV criteria
• You experience at least one upper digestive symptom, such as heartburn, acid reflux, stomach pain or burning, feeling full quickly, bloating, burping, nausea, or vomiting
• You have signs of anxiety, depression, or stress, shown by scoring above a certain level on at least one part of a standard questionnaire called the DASS-21

Who may not be able to join:

• You have tested positive for a stomach bacteria called Helicobacter pylori, either during the camera test or through a separate breath test
• You are currently taking medication for anxiety or depression
• You have taken antibiotics at any point in the past month
• You have used symptom-relief medications, probiotics, or acid-reducing medications (called proton pump inhibitors or PPIs) in the past two weeks
• You have had surgery on any part of your digestive system in the past
• The camera tests find physical problems such as ulcers, active inflammation, or certain types of bowel growths (polyps)
• You are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.