What changed for Obesity
A plain English summary of what recently moved in the public data Voxsanity tracks for Obesity. Updated from government registries. Not medical advice.
How to read these changes: every figure on this page is the difference between two snapshots of what Voxsanity had tracked on each date. Voxsanity only began taking daily snapshots in July 2026 and is still ingesting the public registries, so a rise here is mostly our own coverage expanding rather than new research appearing. Read it as our tracked coverage growing, not as a claim about real-world research changing this fast: it overstates how much actually changed.
Comparing the two most recent snapshots, 27 July 2026 and 28 July 2026.
- Trials recruiting worldwide 525 to 543 (+18)
- Late-stage (Phase 3) trials 25 to 26 (+1)
- Trials on record 5,153 to 5,328 (+175)
Newly subsidised on the PBS
No medicines were newly subsidised on the PBS for Obesity in July 2026. Voxsanity tracks 2 PBS-subsidised medicines for this condition; none of them was listed for the first time this month.
Source: Pharmaceutical Benefits Scheme (PBS), © Commonwealth of Australia. Data used and redistributed under permission; not modified from its original wording where displayed verbatim.
Past updates
Tracking began in July 2026. Month on month changes will appear here once a second month of data has been recorded. Until then, the comparison above shows the most recent movement.
Recent trend
Weekly, most recent weeks (fills out to a monthly trend as history grows).
Recent trial results
The 30 most recent of 84 trials tracked for Obesity that have reported results to a public registry.
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
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NCT03226821 · results posted 19 May 2026
According to the results reported on ClinicalTrials.gov, six people took part in this trial, all of whom received the study drug tesamorelin. The trial was measuring several things in the body, including the amount of fat stored in the liver (called hepatic lipid content), the amount of fat stored deep in the abdomen around the organs (called visceral adipose tissue), activity of certain genes in fat tissue, and resting energy use. Notably, none of the six participants were recorded as having completed the study — all six did not finish. The reported data shows three figures for liver fat con...
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NCT04007393 · results posted 5 May 2026
According to the results reported on ClinicalTrials.gov, this trial (NCT04007393) enrolled 150 participants in total across eight groups. The trial was comparing different combinations of a lifestyle and medical treatment programme — referred to as "LSMT" — run over either 12 or 24 weeks, with some groups also receiving the medications phentermine and/or topiramate, and others receiving a placebo (a dummy treatment with no active ingredient). The main thing the trial was measuring was the percentage change in BMI (Body Mass Index, a number calculated from a person's height and weight) from the...
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NCT06034457 · results posted 19 December 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 180 people in a single group — meaning everyone received the same program, and there was no comparison group. The study looked at a combined behavioural weight-management program (WW, including its clinic-based medication support service, formerly known as Sequence) over 24 weeks. Of the 180 people who started, 166 completed the study and 14 did not finish. The reported data shows that, on average, participants lost 27.41 pounds over the 24 weeks. In terms of how many people reached certain milestones, the data repor...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04291560 · results posted 17 November 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT04291560) enrolled 108 pregnant women — 53 in a programme called "Prenatal Heart Smart" and 55 receiving usual care. All participants who started the trial completed it, with no drop-outs recorded. The study was measuring changes in blood pressure (both the top number, called systolic, and the bottom number, called diastolic) during the later stages of pregnancy — at around 27 weeks (the starting point), 32 weeks, and 37 weeks. It also set out to measure changes in the balance between two parts of the nervous system that i...
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NCT04042467 · results posted 16 October 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT04042467) involved 900 participants split into two groups — 449 in the "Greenlight Plus" group and 451 in the "Greenlight" group. The trial followed young children over two years, tracking their weight-for-length measurements (a way of assessing a child's weight relative to their height) recorded during regular paediatric care visits. Both groups received a version of the Greenlight programme, with one group receiving an enhanced version ("Greenlight Plus"). The reported data shows that children in both groups followed a...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05616013 · results posted 18 July 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT05616013) enrolled 509 participants across nine different treatment groups. The groups tested various combinations and doses of two drugs — bimagrumab (given by infusion) and semaglutide (an injection) — alongside placebo (dummy treatment) groups, over a period of up to 72 weeks. The trial's main goal was to measure how much participants' body weight changed from their starting weight by week 48. Secondary goals included measuring changes in waist circumference and body fat mass (measured using a special type of body scan...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04636437 · results posted 2 July 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT04636437) enrolled 147 people living with HIV who were already on treatment — 49 in each of three groups. One group switched to a combination called doravirine (DOR) with TAF/FTC, a second group switched to doravirine with TDF/FTC, and a third group stayed on their existing treatment (an INSTI-based regimen with TAF/FTC). The trial was primarily measuring changes in body weight over 48 weeks, and also tracked waist circumference and blood fat levels (triglycerides) at 24 and 48 weeks. By the end of the study, 39, 45, and 4...
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NCT04851587 · results posted 6 June 2025
According to the results reported on ClinicalTrials.gov, this was a pilot study — meaning it was a small, early-stage trial designed to gather information to help decide whether a larger, more definitive trial should go ahead. It tested a program called the "Empower Intervention." A total of 37 people were enrolled, 33 went on to receive the intervention, and 19 fully completed the study. The trial did not have a single main outcome it was testing; instead, it looked at several descriptive measures such as how engaged participants were, how satisfied they were, and how believable they found th...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05136430 · results posted 9 May 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 55 people in total — 27 in a group that received self-regulation strategies combined with guidance on making larger lifestyle changes (called the SR group), and 28 in a group that received healthy lifestyle education (called the LE group). Nearly all participants finished the trial (25 from the SR group and 27 from the LE group). The trial was measuring things related to quitting smoking and weight change, and was also checking whether the program was feasible to run by tracking how often participants attended their s...
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NCT03748342 · results posted 17 April 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT03748342) enrolled 97 participants in total — 48 in the Standard Endotracheal Tube group and 49 in the Second-Generation LMA (a type of airway device that sits in the throat rather than passing into the windpipe) group. All participants who started the trial completed it. The trial was measuring whether patients experienced low oxygen levels (hypoxia) after surgery while recovering in the post-anaesthesia care unit (PACU), as well as tracking changes in blood pressure, heart rate, and oxygen levels in the blood during and...
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NCT03254940 · results posted 10 April 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT03254940) enrolled a total of 537 participants across 32 different study groups. Each group received a different combination of text message-based components aimed at weight management — for example, variations in the type of diet plan, the style of messaging, how often messages were sent, and the kind of feedback provided. The trial was measuring whether these different combinations had any effect on participants' weight, diet quality, and physical activity levels over six months. The reported data shows that for the pri...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05966870 · results posted 12 February 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT05966870) enrolled 22 participants who regularly drank sugar-sweetened beverages (SSBs — drinks like soft drinks or juice with added sugar). The trial asked participants to swap those drinks for unsweetened sparkling water over a 12-week period. The study was measuring several things: how much participants' drink choices changed, and whether there were any changes in blood sugar levels, a longer-term blood sugar marker called HbA1c (a blood test that reflects average blood sugar over roughly three months), and the body's r...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04520256 · results posted 15 January 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 384 participants in total, spread evenly across 32 different groups of 12 people each. The trial was testing a weight management programme that combined a core set of activities with various optional add-on components — including social support, strategies for managing dysregulated eating, exercise, feedback, and virtual reality (VR). Each group received a different combination of these add-ons, allowing the researchers to measure whether each individual component made a difference to weight change over 12 months. Th...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02122666 · results posted 26 October 2024
According to the results reported on ClinicalTrials.gov, this trial involved 27 people in total — 12 in a group with a condition called metabolic syndrome (a cluster of health factors such as high blood sugar, excess body fat around the waist, and abnormal cholesterol levels) and 15 in a healthy control group. All 27 participants completed the study with no dropouts. The trial was measuring differences between the two groups in the composition of a specific structure inside muscle cells (called the sarcoplasmic reticulum), as well as measures related to how the body handles insulin and sugar,...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03529695 · results posted 23 October 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT03529695) involved two groups of participants: mothers and their young children. A total of 35 mothers and 35 children were enrolled in a standard home visiting programme (called the Standard HVP Curriculum), while 42 mothers and 42 children were enrolled in an obesity prevention version of the programme. The trial was measuring mothers' body weight (using a measure called BMI — a number calculated from height and weight) and infants' weight in pounds, as well as how often participants ate certain foods such as fruit, vege...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03762135 · results posted 26 August 2024
According to the results reported on ClinicalTrials.gov, this trial involved 78 young people (adolescents) who were split into two groups. Fifty-two participants used a full version of a smartphone app called LIITah, while 26 used a partial version of the app that included only two features (called ELI and SNAP). All 78 participants completed the study — none dropped out. The trial tracked how often the young people visited fast food restaurants, how many calories they purchased at those restaurants, and their Body Mass Index (BMI) percentile (a measure of body weight relative to height, compa...
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NCT04788511 · results posted 11 June 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT04788511) enrolled 529 people in total — 263 received semaglutide 2.4 mg and 266 received a placebo (an inactive injection). The trial ran for approximately 52 weeks and was measuring two main things: changes in heart failure symptoms and quality of life (using a standardised questionnaire called the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score, or KCCQ-CSS, where higher scores mean better health), and changes in body weight. The reported data shows that, on the KCCQ-CSS questionnaire (scored from 0 to...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT00776035 · results posted 3 May 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT00776035) enrolled 19 people with heart failure — 9 men and 10 women. All 19 participants completed the study with no dropouts. The trial was measuring two things in the heart: how much blood flows through the heart muscle, and how much fatty acid (a type of fuel the heart uses for energy) the heart muscle uses. Both were measured using a specialised imaging scan called a PET scan, which tracks small amounts of injected substances as they move through the body. The reported data shows that, on average, blood flow through...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT01868230 · results posted 28 February 2024
According to the results reported on ClinicalTrials.gov, this trial enrolled 148 women in total — 74 in a "Lifestyle Intervention" group and 74 in a "Health and Wellness" comparison group. The trial was looking at weight changes during and after pregnancy, as well as blood sugar-related measurements, in women who had been diagnosed with gestational diabetes (diabetes during pregnancy). Participants were followed at six weeks, six months, and twelve months after giving birth, though the number who provided data at each of those check-in points was smaller than the number who started. The repor...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02751814 · results posted 14 December 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled 175 participants — young children attending early childhood education (ECE) centres. Of those, 112 completed the starting assessments and 130 completed the study overall. The trial was measuring changes in children's physical activity levels, screen time, movement skills, and sedentary behaviour (time spent sitting or inactive) over approximately one year, comparing what was happening at the start of the study to what was happening at the one-year follow-up point. The reported data shows that for the primary measure...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03382782 · results posted 8 December 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled people across three cohorts and three groups: a Behavioural Weight Loss Intervention (BWLI) group, a group receiving both BWLI and support from a Peer Navigator, and an Integrated Care group (described as treatment as usual). In total, across all three cohorts, 234 people started the trial and the large majority completed it. The trial was measuring changes in body weight and waist circumference as the main (primary) outcome, along with a number of secondary outcomes including quality of life, sense of personal recove...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04667377 · results posted 2 November 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT04667377) enrolled 387 participants across five groups. Four groups received different doses of an investigational medicine called BI 456906 (planned maintenance doses of 0.6 mg, 2.4 mg, 3.6 mg, or 4.8 mg), while a fifth group received a placebo (an inactive treatment with no medicine). The trial was primarily measuring the percentage change in participants' body weight over approximately 46 weeks (about 11 months). The reported data shows that, by week 46, the placebo group's body weight had changed by an average of −2.8...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04881760 · results posted 13 September 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT04881760) enrolled 338 people across seven groups. Participants were given either a placebo (a dummy injection with no active ingredient) or one of several doses of an investigational medicine called LY3437943, delivered in different ways of building up to the final dose. The trial's main goal was to measure the percentage change in body weight over the course of the study. The reported data shows that, for the primary measurement of body weight change, the placebo group lost an average of about 1.6% of their body weight....
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02813668 · results posted 8 September 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled 2,108 people in a single group called the Lifestyle Intervention Training Program. A total of 1,358 participants completed the study, while 750 did not finish. The trial was measuring whether participants could improve on at least two out of three heart and metabolic health markers — specifically, a meaningful drop in a blood sugar measure called HbA1c (a percentage that reflects average blood sugar over roughly three months), a drop in the top number of a blood pressure reading, and a drop in a blood fat called trigl...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03856047 · results posted 18 July 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT03856047) enrolled 706 participants across seven groups. Five groups received different doses of an investigational medication called cagrilintide (0.3 mg, 0.6 mg, 1.2 mg, 2.4 mg, or 4.5 mg), one group received an already-approved weight-management medicine called liraglutide 3.0 mg, and one group received a placebo (an inactive dummy injection). Each group had roughly 99–102 participants at the start, and the trial ran for 26 weeks. The main thing being measured was the percentage change in body weight from the start to t...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03374956 · results posted 18 July 2023
According to the results reported on ClinicalTrials.gov, this trial involved 193 people in total — 93 in the intervention group and 100 in the control group. All participants completed the study, with no drop-outs recorded in either group. The trial was measuring changes in body weight over the course of the study, comparing the two groups against each other. The reported data shows that, on average, people in the intervention group lost about 7.7% of their body weight, while people in the control group lost about 6.5% of their body weight. The trial also looked at how many people in each gro...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT00996866 · results posted 3 July 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT00996866) involved 27 people in total — 13 in a placebo group (receiving a dummy treatment) and 14 in a Vitamin D3 group. All 27 participants completed the study with no drop-outs. The trial was measuring levels of a form of vitamin D in the blood, known as 25(OH)D, which is the standard marker used to assess how much vitamin D a person has in their body. Levels were measured at the start of the trial and again after two months. The reported data shows that at the start of the trial, average blood vitamin D levels were si...
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NCT03009110 · results posted 1 June 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT03009110) enrolled 1,624 participants in total — 816 in the group that received a dressing called prophylactic negative pressure wound therapy (NPWT, a type of sealed dressing that applies gentle suction to a wound), and 808 in the group that received a standard wound dressing. The trial was measuring rates of surgical site infections (SSIs — infections that develop at the site of a surgical cut) and other wound complications after surgery. The vast majority of participants in both groups completed the study (806 in the NP...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02653092 · results posted 1 June 2023
According to the results reported on ClinicalTrials.gov, this trial (NCT02653092) looked at how free fatty acids (FFAs — a type of fat found in the blood) and diet-related changes might affect reproductive hormones, specifically hormones called LH (luteinising hormone) and FSH (follicle-stimulating hormone), which play a role in the menstrual cycle. The trial was split into two groups: one group (Aim 1) explored what happened to hormone levels after participants received FFAs either as a short-term infusion or through a longer-term high-fat diet, while the second group (Aim 2) underwent a proc...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03686150 · results posted 19 April 2023
According to the results reported on ClinicalTrials.gov, this trial involved children receiving vitamin D3 supplements and was run in two parts. A total of 112 participants started the trial across six groups. Part 1 (four groups, 48 participants in total) was designed to work out the best dose of vitamin D3 to use in Part 2. Part 2 (two groups, 64 participants in total) then tested those doses and measured how many children reached a vitamin D blood level of 40 ng/ml or higher — a target level the researchers had set in advance. Most participants finished the trial, with only nine people acro...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
See all 84 reported results for Obesity
These are the results as reported to the registry, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
What is coming
AI generated pipeline summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to NIH funding data, obesity research is currently receiving a very large amount of public funding from the United States government, and this investment has remained broadly steady over recent years. This level of sustained commitment suggests that obesity is treated as a serious and ongoing public health priority by one of the world's largest research funders. For patients, this signal...
Not medical advice. Voxsanity republishes public government health data in plain English. These figures describe research and registry activity, not the suitability of any treatment for any person. Trial status can change; always verify current status directly with the trial site and confirm Australian availability with your doctor.