What changed for OCD
A plain English summary of what recently moved in the public data Voxsanity tracks for OCD. Updated from government registries. Not medical advice.
How to read these changes: every figure on this page is the difference between two snapshots of what Voxsanity had tracked on each date. Voxsanity only began taking daily snapshots in July 2026 and is still ingesting the public registries, so a rise here is mostly our own coverage expanding rather than new research appearing. Read it as our tracked coverage growing, not as a claim about real-world research changing this fast: it overstates how much actually changed.
Comparing the two most recent snapshots, 27 July 2026 and 28 July 2026.
- Trials recruiting worldwide 112 to 115 (+3)
- Trials on record 659 to 665 (+6)
Newly subsidised on the PBS
No PBS-reviewed medicines are tracked for OCD yet, so new PBS listings cannot be reported for it. This is a gap in what Voxsanity has mapped, not a statement that no medicines are subsidised — check the PBS directly.
Past updates
Tracking began in July 2026. Month on month changes will appear here once a second month of data has been recorded. Until then, the comparison above shows the most recent movement.
Recent trend
Weekly, most recent weeks (fills out to a monthly trend as history grows).
Recent trial results
The 30 most recent of 44 trials tracked for OCD that have reported results to a public registry.
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
-
NCT05237466 · results posted 16 July 2026
According to the results reported on ClinicalTrials.gov, this trial enrolled 36 people in total — 18 in a programme called RECLAIM (Reducing Clutter and Increasing Meaning) and 18 in a comparison group called Sorting Practice. The trial was measuring things like how often participants sorted or got rid of items, their readiness to make changes, and levels of apathy (a reduced drive to do things). It is worth noting that a significant number of participants did not finish the trial: 9 of the 18 in the RECLAIM group and 11 of the 18 in the Sorting Practice group did not complete it. The reporte...
Read the full trial page · View reported results on ClinicalTrials.gov ↗
-
NCT04225624 · results posted 10 March 2026
According to the results reported on ClinicalTrials.gov, this trial took place in two phases. In the first phase, 3 people took part in a small pilot test of the programme. In the second phase, 62 people were randomly placed into one of two talking-therapy groups: 31 received a therapy focused on training attention as part of an emotion regulation approach (called AR-ERT), and 31 received a more general supportive psychotherapy (SPT). The trial was primarily measuring levels of repetitive negative thinking — that is, how much people found themselves stuck in unhelpful, looping thoughts. It als...
-
NCT04075890 · results posted 12 December 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT04075890) enrolled 66 people in total — 32 healthy volunteers and 34 people with OCD (Obsessive-Compulsive Disorder). Each group was split further depending on whether they received brain scanning (fMRI) first or a type of mild brain stimulation called tDCS (transcranial direct current stimulation) first, before crossing over to the other. The trial was measuring three things: how strongly people used a deliberate, goal-directed style of decision-making (rather than acting out of habit); how long people could tolerate look...
-
NCT02843308 · results posted 21 November 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT02843308) involved 41 people in total, split into two groups: 21 people who received treatment straight away (the "Immediate Treatment" group) and 20 people who were placed on a waiting period before receiving treatment (the "Delayed Treatment" group). The trial was measuring hoarding-related symptoms using a questionnaire called the Saving Inventory-Revised (SI-R), which asks 23 questions about difficulties with throwing things away, collecting too many items, and living with clutter. The total score on this questionnaire...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT03734705 · results posted 29 May 2025
According to the results reported on ClinicalTrials.gov, this trial involved 32 people in total — 17 in a group that did a type of writing exercise called "imaginal exposure writing" (where participants wrote about distressing hoarding-related scenarios) and 15 in a group that did neutral, everyday writing. All 32 participants completed the trial with no drop-outs. The trial was measuring hoarding-related symptoms and thought patterns using several questionnaire-based scales, before and after the writing exercises. The reported data shows the following score changes across the two groups. For...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT04922502 · results posted 15 January 2025
According to the results reported on ClinicalTrials.gov, this trial involved 136 children with anxiety, split into two groups. One group of 66 received "Standard SPACE" (a therapist-delivered treatment programme), while the other group of 70 received a "Bibliotherapy, Low Therapist Contact SPACE" version — meaning families worked mainly through written materials with less direct therapist involvement. Of those who started, 60 in the first group and 62 in the second group completed the trial. The trial's main measurement was a clinician-rated scale called the Pediatric Anxiety Rating Scale, wh...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT04136626 · results posted 25 November 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT04136626) enrolled 120 people with OCD — 60 in a program called "Perspectives OCD" and 60 in a comparison program called "The Health and Well-Being Program." The trial was measuring OCD symptom severity, depression, day-to-day functioning, and quality of life across three time points: before the program started, at the end of 12 weeks of treatment, and after a 12-month follow-up period. By the end of the full 12-month follow-up, 49 people in the Perspectives OCD group and 39 in the comparison group had completed all stages...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT03828461 · results posted 1 April 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT03828461) involved 13 participants who all received a combination treatment referred to as "BITS + VR" — a behavioural therapy approach paired with virtual reality. The trial was measuring changes in hoarding-related symptoms, specifically how much difficulty people had with clutter, discarding items, and acquiring new possessions. Of the 13 people who started, 9 completed the trial and 4 did not finish. The reported data shows that the primary outcome — hoarding symptom severity — was measured using a questionnaire calle...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT04792645 · results posted 1 August 2023
According to the results reported on ClinicalTrials.gov, this trial looked at a medication called memantine compared to a placebo (a dummy pill with no active ingredient) in people with trichotillomania (compulsive hair pulling) or skin picking disorder. A total of 100 people were enrolled — 45 in the placebo group and 55 in the memantine group. Of those, 36 placebo participants and 43 memantine participants completed the study. The trial ran for 10 weeks and used several questionnaires to measure the severity of symptoms, day-to-day functioning, and mood over 8 weeks of treatment. The report...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT03239210 · results posted 3 July 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled 62 people in total — 33 in the ondansetron group and 29 in the placebo (dummy treatment) group. Of those, 27 and 24 respectively completed the study. The trial was investigating whether ondansetron, a medication more commonly known for treating nausea, had any effect on brain activity and symptom scores in participants, likely in the context of a condition involving tics or obsessive-compulsive symptoms. Brain activity was measured using a type of brain scan (fMRI) that tracks blood flow as a stand-in for brain activi...
-
NCT03530800 · results posted 2 June 2022
According to the results reported on ClinicalTrials.gov, this trial (NCT03530800) looked at a medication called dronabinol (a synthetic cannabinoid) compared to a placebo (a dummy pill with no active ingredient) in people with trichotillomania (compulsive hair-pulling) and/or skin-picking conditions. A total of 50 people took part — 25 in the dronabinol group and 25 in the placebo group. The trial ran for 10 weeks, and the main things being measured were the severity of hair-pulling symptoms and skin-picking symptoms, using two standardised questionnaires scored at the start and end of the stu...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT02028247 · results posted 11 November 2021
According to the results reported on ClinicalTrials.gov, this trial enrolled 167 children or young people across three groups: 77 received a personalised form of cognitive-behavioural therapy (CBT — a talking therapy that helps people manage their thoughts and feelings), 71 received a standard version of CBT, and 19 received treatment as usual (their normal care). By the end of the study, 67, 59, and 15 participants respectively had completed the trial. The trial was measuring changes in anxiety symptoms and related impacts over 16 weeks, using several questionnaires and clinician ratings. Th...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01302080 · results posted 8 October 2021
According to the results reported on ClinicalTrials.gov, this trial enrolled 941 participants in total — 696 in the Sertraline group and 245 in the Psychotherapy group. Of those, 330 in the Sertraline group and 102 in the Psychotherapy group completed the study. The trial was measuring changes in a type of thinking and mental processing ability — specifically, how quickly and accurately people could complete a task called the "Trail B" test, which involves connecting numbered and lettered circles in a specific alternating order as fast as possible. This was tracked at six points over 30 months...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT02797808 · results posted 5 January 2021
According to the results reported on ClinicalTrials.gov, this trial (NCT02797808) involved two groups of children: 23 children diagnosed with obsessive-compulsive disorder (OCD) and 18 children without OCD who acted as a comparison group. The trial was measuring the severity of OCD symptoms over 12 weeks, as well as looking at brain activity patterns — specifically how different parts of the brain communicate with each other at rest — using brain scans (fMRI). Of those who started, 16 children with OCD and 15 children without OCD completed the study. The reported data shows that OCD symptom s...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT02473913 · results posted 4 November 2020
According to the results reported on ClinicalTrials.gov, this trial looked at milk thistle as a possible treatment for trichotillomania — a condition where people repeatedly pull out their own hair. The study enrolled 22 people in total (11 in each group) and used a "crossover" design, meaning everyone tried both milk thistle and a placebo (a dummy treatment with no active ingredient) at different points across a 13-week period. By the end of the study, 8 people in each group had completed the trial, with 3 from each group not finishing. The reported data shows that the main thing being measu...
-
NCT02911324 · results posted 28 February 2020
According to the results reported on ClinicalTrials.gov, this trial looked at nabilone (a synthetic cannabis-like medication) in people with obsessive-compulsive disorder (OCD). A total of 16 people took part — 9 in a group receiving nabilone alone, and 7 in a group receiving nabilone combined with a type of therapy called EX/RP (exposure and response prevention, a talking therapy for OCD). Twelve participants completed the study — 6 in each group. The trial measured changes in OCD symptom severity using a standard rating tool called the Yale-Brown Obsessive Compulsive Scale (YBOCS), which run...
-
NCT02040805 · results posted 11 February 2020
According to the results reported on ClinicalTrials.gov, this trial involved 323 adults in total — 160 assigned to a Group Cognitive-Behavioral Therapy (CBT) program and 163 assigned to a Peer Facilitated Support Group. By the end of the study, 118 people in the CBT group and 113 in the peer support group had completed it, meaning 42 and 50 people respectively did not finish. The trial was measuring hoarding symptoms and their impact on daily life, using two self-reported questionnaires: the Saving Inventory-Revised (SI-R), which scores hoarding severity from 0 to 92 (with scores of 42 or abov...
-
NCT02205177 · results posted 5 August 2019
According to the results reported on ClinicalTrials.gov, this trial looked at an app called "Anxiety Coach" as a tool for children and adolescents experiencing anxiety. Ten young people took part in total — eight were assigned to a group that used the app alongside face-to-face sessions with an anxiety coach (FTF-AC), and two were assigned to a group that used the app with only minimal contact with a coach (MC-AC). Of those who started, six from the face-to-face group and both participants from the minimal-contact group completed the study. The main thing being measured was how anxiety sympto...
-
NCT03002753 · results posted 16 April 2019
According to the results reported on ClinicalTrials.gov, this trial looked at three approaches for people with obsessive-compulsive disorder (OCD): a technique called Detached Mindfulness, a technique called Cognitive Restructuring, and a Waitlist group (where participants waited without receiving either technique). In the first round of the trial, 10 people started in the Detached Mindfulness group, 12 in the Cognitive Restructuring group, and 21 in the Waitlist group. There was also a second round of randomisation — where some participants were reassigned — with 11 starting in the Detached M...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT02671266 · results posted 23 November 2018
According to the results reported on ClinicalTrials.gov, this trial enrolled 41 people in total across two groups — 20 in one group and 21 in the other. Participants included people diagnosed with Body Dysmorphic Disorder (BDD), people with Obsessive-Compulsive Disorder (OCD), and healthy volunteers with no diagnosis. The trial used a "crossover" design, meaning everyone received both a nasal oxytocin spray and a placebo (an inactive spray with no medicine) at different times, so the two groups reflect the order in which they received each. The trial was measuring whether oxytocin influenced h...
-
NCT02059980 · results posted 26 September 2018
According to the results reported on ClinicalTrials.gov, this trial looked at a type of brain training called "response inhibition training" — essentially practising the ability to stop or hold back automatic actions — in people with either obsessive-compulsive disorder (OCD) or trichotillomania (a condition involving repetitive hair pulling). A total of 33 people started the trial: 18 in the active training group and 15 in a placebo (inactive) control group. Of those, 16 and 14 respectively completed the study, with a small number dropping out from each group. The reported data shows two mai...
-
NCT01411774 · results posted 23 January 2018
According to the results reported on ClinicalTrials.gov, this trial involved 142 young people, split into two groups. One group of 72 received cognitive-behavioural therapy (a structured talking therapy often called CBT) alongside a placebo pill — a dummy pill with no active ingredient. The other group of 70 received the same CBT alongside a medication called D-cycloserine. The trial was measuring the severity of obsessive-compulsive disorder (OCD) symptoms in both groups after treatment. The reported data shows that OCD symptom severity was measured using a tool called the Children's Yale-Br...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01875445 · results posted 19 May 2017
According to the results reported on ClinicalTrials.gov, this trial looked at whether inositol (a naturally occurring sugar-like substance) compared to a placebo (a dummy treatment with no active ingredient) might affect hair-pulling behaviour, a condition sometimes called trichotillomania. A total of 38 people took part — 19 in the placebo group and 19 in the inositol group — and the study ran for 10 weeks per person. Notably, the reported data shows that 7 people in the placebo group did not complete the study, while all 19 in the inositol group finished. The reported data shows that two ra...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT00956085 · results posted 10 May 2017
According to the results reported on ClinicalTrials.gov, this trial involved 12 adults who were given a medication called memantine. All 12 participants completed the study — none dropped out. The trial was measuring changes in obsessive-compulsive symptoms using a well-established rating tool called the Yale-Brown Obsessive-Compulsive Scale (YBOCS), which scores symptoms on a scale from 0 to 40, where a higher score means more severe symptoms. The main thing the researchers were looking at was how many participants showed a meaningful improvement, which they defined as a reduction of at least...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT02267629 · results posted 10 May 2017
According to the results reported on ClinicalTrials.gov, this trial looked at a drug called Rapastinel (also known as GLYX-13) in people with Obsessive Compulsive Disorder (OCD). A total of 7 people took part, and all 7 completed the study. The trial was measuring changes in OCD symptoms — specifically obsessive thoughts and compulsive behaviours — using two rating scales where higher scores mean more severe symptoms. One scale (called the YBOCCS) asked participants to rate their own symptoms over the previous hour, and the other (called the YBOCS) is a commonly used tool for measuring OCD sev...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT00464698 · results posted 7 March 2017
According to the results reported on ClinicalTrials.gov, this trial involved 20 people in total, all of whom received a medication called duloxetine for obsessive-compulsive disorder (OCD). The trial used a stepped-dose design across three periods: participants started on a lower dose (30 mg), then moved to a medium dose (60 mg), and finally a higher dose (120 mg). Not everyone completed every stage — 17 finished the first period, 17 finished the second, and 12 finished the third. The main thing the trial was measuring was change in OCD symptom severity using a standard rating tool called the...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01404208 · results posted 27 February 2017
According to the results reported on ClinicalTrials.gov, this trial involved 142 children and young people — 70 in the D-Cycloserine group and 72 in the sugar pill (placebo) group. The trial was measuring the severity of obsessive-compulsive disorder (OCD) symptoms in participants who were also receiving behaviour-based therapy. Two tools were used to track changes: a detailed symptom checklist called the CY-BOCS (scored 0–40, where higher numbers mean more severe symptoms), and a clinician's overall rating of illness severity called the CGI-Severity (scored 0–6, where higher numbers mean more...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01063348 · results posted 31 October 2016
According to the results reported on ClinicalTrials.gov, this 12-week trial looked at a supplement called N-Acetyl Cysteine (sometimes called NAC) as a possible treatment for pathological skin picking. A total of 66 people took part — 35 in the NAC group and 31 in the placebo (dummy treatment) group. By the end of the study, 32 people in the NAC group and 21 in the placebo group had completed all 12 weeks. The main thing being measured was a questionnaire score called the NE-YBOCS, which rates the severity of skin picking urges and behaviours on a scale from 0 to 40 (higher scores mean more s...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01100255 · results posted 27 October 2016
According to the results reported on ClinicalTrials.gov, this trial involved 15 people in total — 8 in Group A and 7 in Group B. All 15 participants completed the study with no drop-outs. The trial was measuring obsessive-compulsive symptoms using a standard questionnaire called the Yale-Brown Obsessive-Compulsive Scale (YBOCS), which scores symptoms from 0 (no symptoms) to 40 (most severe). The researchers were looking at how many participants showed a meaningful drop in their score — specifically, a reduction of at least 35% — after receiving either a saline (saltwater) infusion or a ketamin...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
-
NCT01654523 · results posted 22 July 2016
According to the results reported on ClinicalTrials.gov, this trial involved 20 people who were enrolled in the study, with 19 completing it and 1 not finishing. The trial was measuring the use of a device called an Awareness Enhancement and Monitoring Device, which was being tested in people with trichotillomania — a condition involving repetitive hair pulling. The main thing the researchers were tracking was how scores on a standard hair-pulling severity scale (the Massachusetts General Hospital Hairpulling Scale) changed between the start of the trial and the end of treatment. The reported...
See all 44 reported results for OCD
These are the results as reported to the registry, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
What is coming
AI generated pipeline summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to NIH funding data, a substantial amount of public research money is currently directed toward OCD, and that investment has remained broadly steady from year to year. This pattern of consistent support suggests that OCD is regarded as a meaningful research priority by one of the world's largest public funders of medical science. For patients, steady and substantial funding generally mea...
Not medical advice. Voxsanity republishes public government health data in plain English. These figures describe research and registry activity, not the suitability of any treatment for any person. Trial status can change; always verify current status directly with the trial site and confirm Australian availability with your doctor.