What changed for Sleep Disorders
A plain English summary of what recently moved in the public data Voxsanity tracks for Sleep Disorders. Updated from government registries. Not medical advice.
How to read these changes: every figure on this page is the difference between two snapshots of what Voxsanity had tracked on each date. Voxsanity only began taking daily snapshots in July 2026 and is still ingesting the public registries, so a rise here is mostly our own coverage expanding rather than new research appearing. Read it as our tracked coverage growing, not as a claim about real-world research changing this fast: it overstates how much actually changed.
Comparing the two most recent snapshots, 27 July 2026 and 28 July 2026.
- Trials recruiting at Australian sites 8 to 9 (+1)
- Trials recruiting worldwide 588 to 597 (+9)
- Trials on record 4,574 to 4,718 (+144)
Newly subsidised on the PBS
No PBS-reviewed medicines are tracked for Sleep Disorders yet, so new PBS listings cannot be reported for it. This is a gap in what Voxsanity has mapped, not a statement that no medicines are subsidised — check the PBS directly.
Past updates
Tracking began in July 2026. Month on month changes will appear here once a second month of data has been recorded. Until then, the comparison above shows the most recent movement.
Recent trend
Weekly, most recent weeks (fills out to a monthly trend as history grows).
Recent trial results
The 30 most recent of 112 trials tracked for Sleep Disorders that have reported results to a public registry.
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
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NCT07598123 · results posted 16 July 2026
According to the results reported on ClinicalTrials.gov, this trial enrolled 80 people in total — 40 in a multi-component group exercise program and 40 in a routine community activities group. The trial was measuring several aspects of physical fitness in older adults, including walking speed, leg strength, arm strength, hand grip strength, and balance. All 80 participants completed the baseline (starting) assessments. By the end of the trial, 36 out of 40 people finished in the exercise group and 39 out of 40 finished in the community activities group. The reported data shows the following n...
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NCT06050720 · results posted 13 May 2026
According to the results reported on ClinicalTrials.gov, this trial enrolled 40 people who had been identified as having a possible sleep disorder. Of those, 38 completed the study and 2 did not finish. The trial was designed to compare two devices used to measure something called the Apnoea Hypopnoea Index (AHI) — a count of the number of times per hour a person's breathing pauses or becomes very shallow during sleep. Participants wore both devices at the same time, overnight, in their own homes, so the readings from each device could be directly compared. The reported data shows that the pr...
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NCT07384364 · results posted 25 March 2026
According to the results reported on ClinicalTrials.gov, this trial enrolled 19 participants in a single group, all receiving the same intervention. Of those, 16 completed the study and 3 did not finish. The trial was measuring changes in four things: how quickly and steadily people could move (using a timed walking test), how much back pain they reported, how well they slept, and how many times they could stand up and sit down in 30 seconds as a measure of leg strength. The reported data shows the following percentage changes from the start of the trial to the end. On the timed walking test...
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NCT05194735 · results posted 10 November 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 14 participants in total — 1 person assigned to the lowest dose group (Dose Level 1) and 13 people assigned to the middle dose group (Dose Level 2). No participants were enrolled in the highest dose group (Dose Level 3). The trial was testing a type of cell therapy called TCR-T cell therapy, where a person's own immune cells are collected, modified in a laboratory, and then given back to them. The trial was primarily looking at what unwanted health events (called "adverse events") occurred after the treatment, whether...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05780983 · results posted 30 October 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 7 participants in a single group who received education and coaching aimed at developing healthy nighttime sleep and daytime activity behaviours. Six of the seven participants completed the study, and one did not finish. The trial was measuring several aspects of sleep and daily physical activity, including how efficiently participants were sleeping, how severe any sleep difficulties were, how many steps they were taking each day, and how much their sleep was disturbing their daily life. The reported data shows that,...
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NCT03858309 · results posted 29 October 2025
According to the results reported on ClinicalTrials.gov, this trial enrolled 21 people across two groups — 11 in Breathing Group 1 and 10 in Breathing Group 2. The study was measuring the flow of cerebrospinal fluid (the fluid that surrounds the brain and spinal cord) using MRI scans, to see how different breathing practices were associated with the speed and direction of that fluid movement. It also tracked blood pressure, body mass index (BMI), and how often and how long participants did their breathing exercises at home. By the end of the study, 9 people in Group 1 and 7 in Group 2 had comp...
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NCT04171037 · results posted 24 July 2025
According to the results reported on ClinicalTrials.gov, this trial involved 108 people in total — 54 in a group that received oxygen through a device called Optiflow™ THRIVE (a type of high-flow nasal oxygen) and 54 in a control group that received oxygen through a standard face mask. The trial was looking at what happened to patients' oxygen levels during a 60-minute window while they were given a sedation medication called propofol. Specifically, it was measuring how often and for how long patients' blood oxygen levels dropped to a low level (92% or below), which researchers called a "desat...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04154631 · results posted 4 July 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT04154631) involved 489 people across two groups — 175 in the "Standard TranS-C" group and 314 in the "Adapted TranS-C" group. Within each group, participants were either offered the sleep treatment straight away ("Immediate") or placed in a delayed treatment comparison condition ("UC-DT"). The trial also included healthcare providers (30 in the Standard group, 63 in the Adapted group). The study was measuring sleep disturbance, sleep-related impairment, and overall sleep health in patients, as well as how acceptable provid...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05594589 · results posted 3 July 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT05594589) looked at a sleep medication called lemborexant, tested at two doses (5 mg and 10 mg), compared with a placebo (a dummy pill with no active ingredient). A total of 65 people entered an initial placebo run-in phase, after which 13 were assigned to continue with placebo, 26 to lemborexant 5 mg, and 26 to lemborexant 10 mg. Nearly all participants completed the study — one person in the lemborexant 5 mg group did not finish. The trial measured two main things related to sleep: how long it took participants to fall a...
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NCT04532749 · results posted 4 June 2025
According to the results reported on ClinicalTrials.gov, this trial looked at a medicine called seltorexant in people experiencing depression with sleep disturbance. A total of 212 participants were enrolled — 107 received seltorexant and 105 received a placebo (a dummy pill with no active ingredient) — over a treatment period of about six weeks (Day 1 to Day 43), followed by a two-week follow-up period. The trial measured changes in depression severity and sleep disturbance using several standardised questionnaires, where lower scores over time indicated fewer symptoms. The reported data sho...
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NCT06092710 · results posted 3 June 2025
According to the results reported on ClinicalTrials.gov, this trial involved 112 people in total — 52 in a study group who underwent a sleep monitoring test (called polysomnography, or PSG) along with a sleep survey, and 60 in a control group who completed the sleep survey only. All 112 participants finished the trial with no dropouts. The trial was testing a new questionnaire-style scale designed to measure how well a person can perceive changes in airflow through their nose, mouth, and throat, and whether scores on this scale could help identify people at risk of obstructive sleep apnoea (OS...
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NCT05027438 · results posted 11 April 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT05027438) enrolled 36 participants in a single group called "COAST + Deprescribing." The trial was measuring two main things: changes in insomnia severity (using a standard questionnaire called the Insomnia Severity Index, or ISI, scored from 0 to 28 where higher scores mean more severe insomnia) and changes in how much sleep medication participants were taking. It also tracked several sleep diary measures, including how long it took participants to fall asleep, how long they were awake during the night, and how efficientl...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03804788 · results posted 15 January 2025
According to the results reported on ClinicalTrials.gov, this trial (NCT03804788) enrolled 71 eligible participants who had both insomnia and risky drinking. They were split into two groups: 38 people received Cognitive Behavioural Therapy for Insomnia (CBT-I — a structured talking therapy aimed at changing thoughts and habits around sleep), and 33 people received Sleep Hygiene education (general advice about good sleep habits). All 71 participants completed the study. The trial was measuring whether it was practical to run — tracking how many people signed up and stayed, as well as monitoring...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT05299723 · results posted 7 January 2025
According to the results reported on ClinicalTrials.gov, this was a small pilot trial (NCT05299723) that ran in two phases. It looked at a bright light therapy (BLT) intervention for sleep, and was designed to test whether the study itself was practical to run — not to prove whether the treatment works. A total of 19 people started the trial across three groups: 4 in an open-label phase (Phase A), 10 in an active treatment group (Phase B), and 5 in a sleep hygiene education comparison group (Phase B). Of those, 17 completed the study — 2 people in the active treatment group did not finish. Th...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04739423 · results posted 2 December 2024
According to the results reported on ClinicalTrials.gov, this trial enrolled 41 people across three groups: people with Parkinson's disease (PD), people with mild cognitive impairment (MCI), and people with Parkinson's disease dementia or a related condition called dementia with Lewy bodies (DDD or DLB). Participants were split into two sequences — meaning they received either an active treatment or a placebo (a dummy treatment) in a particular order. The trial was measuring things like how well people recognised emotions on faces, whether they experienced fluctuations in thinking and awarenes...
Read the full trial page · View reported results on ClinicalTrials.gov ↗
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NCT04986904 · results posted 23 October 2024
According to the results reported on ClinicalTrials.gov, this trial enrolled 102 participants, all of whom used an online sleep program called SHUTi (Sleep Healthy Using the Internet). The trial was designed to look at how much participants actually engaged with the program, and to measure changes in their sleep-related thoughts and beliefs. All 102 participants were caregivers — people who look after someone else — and the study tracked them through a nine-week period. By the end of the study, 90 participants had fully completed it, while 12 did not finish. The reported data shows that when...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT00581009 · results posted 17 October 2024
According to the results reported on ClinicalTrials.gov, this trial involved 49 people who had been diagnosed with depression. Participants were split into two groups: 17 people received medication only, and 32 people received medication combined with what the researchers called "chronobiological augmentation" — a type of treatment that works with the body's natural daily rhythms (such as sleep-wake cycles and light exposure). All 49 participants completed the study. The trial was measuring changes in depression symptom severity over the first 7 days and up to 7 weeks of treatment, using a sta...
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NCT03968939 · results posted 16 July 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT03968939) enrolled 55 people in total across three groups: 15 received usual care (the control group), 26 received sleep hygiene education, and 14 received over-the-counter sleep aids (25 mg of Benadryl plus 3 mg of melatonin). All 55 participants who started the study completed it. The trial was measuring three things across multiple time points: daytime sleepiness (using a questionnaire called the Epworth Sleepiness Scale, scored 0–24 where higher means more sleepiness), overall sleep quality (using a questionnaire calle...
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NCT02805998 · results posted 25 June 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT02805998) enrolled 208 participants — 105 in a group that received a web-based form of Cognitive Behavioural Therapy for Insomnia (CBT-I, a structured talking-based program delivered online) and 103 who received their usual care. Of those, 91 and 94 participants respectively completed the study. The trial was measuring changes in sleep-related outcomes, including how severe participants rated their insomnia, how efficiently they slept, how long they slept, and their overall sleep quality. It also measured changes in depres...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02995837 · results posted 13 June 2024
According to the results reported on ClinicalTrials.gov, this trial enrolled 19 children diagnosed with Obstructive Sleep Apnea Syndrome (OSAS) — a condition where breathing repeatedly stops during sleep — and 15 children without the condition who acted as a comparison group (controls). The trial was measuring blood flow to the brain (called cerebral blood flow, or CBF) and how it responds when children breathe a mixture of oxygen and carbon dioxide, which is a way of testing how well the brain automatically adjusts its own blood supply. It also looked at thinking and behaviour skills over tim...
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NCT04364191 · results posted 29 May 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT04364191) enrolled 27 people in total — 13 in the intervention arm and 14 in the control arm. Of those, 12 people in each group completed the study (one person left the intervention arm and two left the control arm). The trial measured two main things: how long it took participants to fall asleep (called "sleep latency"), and their self-reported general health and quality of life using a standard questionnaire (the SF-36, scored from 0 to 100, where a higher score means better quality of life). It also tracked a secondary...
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NCT03664765 · results posted 12 March 2024
According to the results reported on ClinicalTrials.gov, this trial (NCT03664765) enrolled 24 people in total — 12 in the exercise intervention group (who undertook upper airway and respiratory muscle training) and 12 in a control group (who received a sham version of the training). The trial was primarily designed to test whether the study itself was practical to run — specifically, whether participants could be recruited and whether they could complete a three-month programme. This type of trial is sometimes called a "feasibility" study, meaning its main purpose was to check if a larger tria...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT02988375 · results posted 12 January 2024
According to the results reported on ClinicalTrials.gov, this trial involved two groups of people who had both insomnia and depression. One group (946 people) received a digital form of Cognitive Behavioural Therapy for Insomnia (dCBTI — an online sleep therapy programme), and the other group (439 people) received sleep education materials. Of those who started, 358 people in the dCBTI group and 300 people in the sleep education group completed the study. The trial was measuring the severity of depression symptoms and the severity of insomnia symptoms at the start, after treatment, and again o...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04570150 · results posted 5 January 2024
According to the results reported on ClinicalTrials.gov, this trial enrolled 90 adults who were having surgery and needed muscle-relaxing medication as part of their anaesthetic. All 90 participants completed the study — 45 received a drug called sugammadex and 45 received a drug called neostigmine, both of which are used to reverse the effects of muscle relaxants at the end of surgery. The trial was measuring how quickly people were ready to leave the post-anaesthesia care unit (PACU — the recovery room after surgery), as well as how their breathing was affected after the operation compared t...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03658954 · results posted 13 November 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled 120 people in total across three groups. One group of 30 received general advice only, a second group of 30 received advice plus tools to track their own sleep (self-monitoring), and a third group of 60 received advice, self-monitoring, and personalised feedback. The trial was measuring how much alcohol participants drank over a 12-week follow-up period, as well as looking at sleep quality, sleep-related daytime difficulties, and how satisfied participants were with their treatment. Most participants completed the stu...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04974515 · results posted 16 October 2023
According to the results reported on ClinicalTrials.gov, this trial looked at a device called eXciteOSA, which is a mouthpiece-style device intended for people with sleep apnoea. A total of 40 people took part — 19 in a lower-intensity group and 21 in a higher-intensity group — and all 40 completed the study. The trial was primarily measuring how consistently participants used the device over the study period, and also tracked several measures related to breathing during sleep, daytime sleepiness, sleep quality, and quality of life. The reported data shows that, on average, participants in bo...
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NCT04091438 · results posted 26 September 2023
According to the results reported on ClinicalTrials.gov, this trial involved 28 people in total (14 in each group), though a small number did not complete all stages. It used a "crossover" design, meaning participants took turns receiving either the study drug TAK-925 (at a dose of 112 mg) or a placebo (an inactive treatment), with a washout period in between. The trial was primarily measuring how often participants experienced unexpected medical events or abnormal test results while taking the drug or placebo, and secondarily looking at how the drug moved through the body in the bloodstream....
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT03745898 · results posted 1 August 2023
According to the results reported on ClinicalTrials.gov, this trial enrolled 98 people with heart failure — 48 received nocturnal oxygen therapy (oxygen delivered during sleep) and 50 received a sham version (a device that looked the same but delivered room air instead of extra oxygen). All 98 participants completed the study. The trial was set up to measure whether nocturnal oxygen therapy made a difference to serious heart-related events, quality of life, mood, and sleep compared to the sham treatment. The reported data shows that for the main outcome — the number of participants who experi...
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
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NCT04726514 · results posted 22 June 2023
According to the results reported on ClinicalTrials.gov, this trial looked at a device called SleepFlex, which is a treatment for sleep apnoea — a condition where breathing repeatedly stops and starts during sleep. Ten people enrolled in the SleepFlex Treatment group, eight of whom completed the study and two did not finish. The trial measured two main things: whether participants experienced any serious device-related health events, and how their sleep apnoea severity changed before and after using the device. Severity was measured using something called the Apnea-Hypopnea Index, or AHI — a s...
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NCT03359096 · results posted 30 March 2023
According to the results reported on ClinicalTrials.gov, this trial looked at whether a device called hypoglossal nerve stimulation (HGNS) — an implanted device used for sleep apnoea — might have any effect on blood pressure. A total of 63 people were enrolled across two groups. The trial used a "crossover" design, meaning each person spent four weeks with the device turned up to its normal therapeutic level, and four weeks with it turned down to a very low "sham" (inactive-like) setting, with a one-week break in between. By the end of the trial, 60 people completed both intervention periods....
View reported results on ClinicalTrials.gov ↗ · Linked publication on PubMed ↗
See all 112 reported results for Sleep Disorders
These are the results as reported to the registry, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
What is coming
AI generated pipeline summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to NIH funding data, sleep disorders currently attract a very large amount of public research funding in the United States, and that level has remained broadly steady over time. For patients, this signals that sleep disorders are an established and ongoing priority within the global research community. Sustained funding at this scale means researchers have the resources to continue inves...
See the full Sleep Disorders page
Not medical advice. Voxsanity republishes public government health data in plain English. These figures describe research and registry activity, not the suitability of any treatment for any person. Trial status can change; always verify current status directly with the trial site and confirm Australian availability with your doctor.