Lupus Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with, or are suspected to have, lupus (SLE), based on recognised medical classification criteria
• People who are able to give their own informed consent to participate
• Close blood relatives (parents, children, brothers, sisters, grandparents, aunts, uncles) of people already enrolled in the study, but only for the genetics part of the study
• For relatives who are minors, a parent or guardian must be able to give informed consent on their behalf
• People with lupus or suspected lupus who are aged 3 years or older, with no upper age limit
• Healthy volunteers who are not related to any participant and are aged 18 or older, with no upper age limit
• Healthy volunteers who are close blood relatives of a participant and are aged 3 or older, with no upper age limit
• For the vascular (blood vessel) studies only, participants must be aged 18 or older, with no upper age limit

Who may not be able to join:

• People with other serious medical conditions that could make it harder for researchers to interpret the lupus study results, including HIV, active cancer, or other significant health problems
• People who have other medical or surgical conditions that the NIH facility would not be adequately equipped to manage
• People who are unable or unwilling to attend follow-up visits, due to distance, social circumstances, or physical limitations
• People whose medical or mental health history, or current treatments, lead the lead researcher to conclude they should be excluded — for example, those needing urgent or acute medical care (confirm with trial site)
• People who are unwilling to take part in research activities or provide samples or data
• People taking medications or having medical conditions that could interfere with the interpretation of study results
• For the vascular studies only — people who have certain medical devices that are not approved as safe for MRI scanning, including brain aneurysm clips, implanted nerve stimulators, pacemakers or defibrillators, cochlear or ear implants, metal fragments in the eye, implanted insulin or drug pumps, or metal shrapnel or bullets (unless cleared by X-ray)
• For the vascular studies only — people with significantly reduced kidney function (confirm with trial site for specific measurement thresholds); these individuals may still join the broader study but would not take part in certain imaging procedures
• For the vascular studies only — women who are pregnant or breastfeeding
• For the vascular studies only — people whose clinical condition is too unstable to safely undergo MRI, as determined by the enrolling doctor
• For the vascular studies only — healthy volunteers who have a known history of heart artery disease, peripheral vascular disease, or artery-hardening conditions
• For the vascular studies only — people under 18 years of age, due to radiation exposure involved and the lack of validated methods for the vascular testing in younger age groups

Important: Always verify eligibility with the trial site directly before applying.