Uveitis Trial, Completed (NCT00476593)

Uveitis Trial, Completed NCT00476593 Sponsor: Norwegian University of Science and Technology Condition: Uveitis

Printed from Voxsanity (voxsanity.com.au) — NCT00476593 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial involved a total of 218 participants across four groups: 32 people who received diclofenac eye drops, 19 who received dexamethasone eye drops, 38 patients with a condition called anterior uveitis (inflammation inside the front part of the eye), and 129 healthy volunteers. The trial was measuring the thickness of the macula — a small but important area at the back of the eye — using a scanning device called an OCT (optical coherence tomography). The researchers looked at whether factors like age, sex, having had children, use of hormonal therapies, or the type of anti-inflammatory eye drops used were linked to differences in macula thickness. Not everyone who started the trial completed it: 22 diclofenac participants, 17 dexamethasone participants, 30 uveitis patients, and 107 healthy volunteers finished the study. The reported data shows that average macula thickness, measured in microns (a micron is one-thousandth of a millimetre), was 268 microns in the diclofenac group, 272 microns in the dexamethasone group, 276 microns in the anterior uveitis patients, and 267 microns in the healthy volunteers. These are the figures as submitted to ClinicalTrials.gov. It is worth noting that no additional breakdown by age, sex, or other factors was included in the structured results data provided, so those detailed findings were not reported in this dataset. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

View full results on ClinicalTrials.gov ↗ · Read the linked publication on PubMed (PMID 20465801) ↗

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Healthy adults who would like to take part as volunteers
Adult patients who have been diagnosed with anterior uveitis (inflammation at the front of the eye) and wish to participate

Who may not be able to join:

Patients with anterior uveitis who also have other health conditions unrelated to their eye inflammation, such as high blood pressure, diabetes, or epilepsy
Patients with additional eye problems or complications caused by their anterior uveitis, such as raised eye pressure or glaucoma
People who have had or currently have swelling at the back of the eye (macular edema) or other complications at the back of the eye related to uveitis
People whose vision is below a certain level of sharpness or clarity (confirm with trial site for exact details)
People who have cataracts or any other conditions that cause cloudiness in the eye
People who are allergic to local anaesthetic or eye drops that widen the pupils
People who have a very strong glasses or contact lens prescription (very short-sighted or very long-sighted)
People who have had surgery inside the eye — though people who had a straightforward LASIK laser eye correction for mild short-sightedness may still be eligible (confirm with trial site)
People who are unable to cooperate well during the trial procedures

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 28 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I found the following past clinical trial relevant to my condition, and wanted to raise it with you. It is no longer recruiting, but I wanted to ask whether similar active trials exist, or whether its results are relevant to my care:

Trial: NCT00476593

Sponsor: Norwegian University of Science and Technology

Phase: Not Applicable

Status: Completed

Condition: Uveitis

More information: https://clinicaltrials.gov/study/NCT00476593

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Healthy adults who would like to take part as volunteers
Adult patients who have been diagnosed with anterior uveitis (inflammation at the front of the eye) and wish to participate

Who may not be able to join:

Patients with anterior uveitis who also have other health conditions unrelated to their eye inflammation, such as high blood pressure, diabetes, or epilepsy
Patients with additional eye problems or complications caused by their anterior uveitis, such as raised eye pressure or glaucoma
People who have had or currently have swelling at the back of the eye (macular edema) or other complications at the back of the eye related to uveitis
People whose vision is below a certain level of sharpness or clarity (confirm with trial site for exact details)
People who have cataracts or any other conditions that cause cloudiness in the eye
People who are allergic to local anaesthetic or eye drops that widen the pupils
People who have a very strong glasses or contact lens prescription (very short-sighted or very long-sighted)
People who have had surgery inside the eye — though people who had a straightforward LASIK laser eye correction for mild short-sightedness may still be eligible (confirm with trial site)
People who are unable to cooperate well during the trial procedures

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 28 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Completed

Phase

Not Applicable

Sponsor

Norwegian University of Science and Technology

Registry

ClinicalTrials.gov

Start date

1 September 2005

Est. completion

1 December 2009

Where this trial is recruiting

🇳🇴 Norway

Primary endpoints

Macular Thickness Measured With the OCT; in Relation to Age, Sex, Reproductive Factors and the Use of Anti-inflammatory Eye Drops in Health; in Uncomplicated Anterior Uveitis.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov