Phase 2 Uveitis Trial, Completed NCT00525902 Sponsor: Oregon Health and Science University Condition: Uveitis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial involved 31 people who received a medicine called adalimumab. The trial was looking at how the medicine affected a condition involving inflammation inside the eye. Researchers tracked participants over time — 30 people reached the 10-week point, and 12 reached the 50-week point. The study was measuring a combined set of goals, where a participant was considered to have met the target if they improved in at least one of four areas (such as better vision, reduced need for other medicines, better control of eye inflammation, or reduced fluid and inflammation visible on eye scans) without getting noticeably worse in any of the others. The reported data shows that, out of the 31 people who started the trial, 21 participants met at least one of those improvement goals at some point during the study. The reported data also shows that 12 participants met those goals at the 50-week stage. No comparison group (such as a placebo or dummy treatment group) was included in the data submitted, so these numbers reflect only the group who received adalimumab. Some figures — such as the exact breakdown of which specific improvement goals were met — were not reported in the submitted data. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 2 Uveitis Trial, Completed

NCT00525902
Completed Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have an autoimmune eye condition called uveitis that is serious enough to threaten your vision.
  • Your uveitis has not responded to prednisone (a steroid) and at least one other medication that suppresses the immune system (such as methotrexate, azathioprine, mycophenolate mofetil, cyclosporine, cyclophosphamide, or chlorambucil), or you were unable to take these medications because of side effects.

Who may not be able to join:

  • You have another serious health condition that could affect your ability to take part in the trial (confirm with trial site).
  • You have previously used or are currently using a medication called cyclophosphamide.
  • You are unwilling or unable to receive multiple injections as part of the trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Completed
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 January 2008
Est. completion
1 September 2010

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Cumulative Endpoint; Cumulative Endpoint

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov