Phase 3 Uveitis Trial, Completed NCT01475643 Sponsor: Bausch & Lomb Incorporated Condition: Uveitis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial compared two eye drop medicines — loteprednol etabonate and prednisolone acetate — in people who had inflammation inside the eye (specifically in a fluid-filled area at the front of the eye called the anterior chamber). A total of 107 people started the trial: 54 in the loteprednol etabonate group and 53 in the prednisolone acetate group. Of those, 40 and 43 people respectively completed the study. The reported data shows that the main thing being measured was the level of inflammation in the front of the eye, scored on a scale from 0 (no inflammation) to 4 (very severe inflammation). At the end of the study, the loteprednol etabonate group had an average score of 0.913, while the prednisolone acetate group had an average score of 0.783. A second measurement looked at something called "flare" — this refers to how much a beam of light scatters when shone into the eye, which is another way of detecting inflammation. That was also scored from 0 to 4. The reported data shows the loteprednol etabonate group had an average flare score of 0.192, compared with 0.341 for the prednisolone acetate group. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Uveitis Trial, Completed

NCT01475643
Completed Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children who are scheduled for a straightforward, routine cataract surgery (surgery to remove a cloudy lens in the eye)

Who may not be able to join:

  • Children who have a serious eye condition, or any other unstable health condition that the doctor believes could interfere with the treatment or follow-up visits
  • Children who have glaucoma, high pressure in the eye, or who are currently using any medication (eye drops or otherwise) to lower eye pressure
  • Children who have previously had a rise in eye pressure caused by steroid medications
  • Children who are known to be allergic to, or cannot take, the study drug or any of its ingredients

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Completed
Phase
Phase 3
Sponsor
Bausch & Lomb Incorporated
Registry
ClinicalTrials.gov
Start date
1 June 2013
Est. completion
2 June 2017

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Anterior Chamber Inflammation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov