Interstitial Lung Disease Trial, Recruiting NCT01776398 Sponsor: Weill Medical College of Cornell University Condition: Interstitial Lung Disease
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Interstitial Lung Disease Trial, Recruiting

NCT01776398
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Healthy Volunteers (Group 1.1):

  • You are 18 years of age or older, of any sex, race, or background
  • You do not have lung disease (smokers and non-smokers are welcome, including those who use cigarettes, e-cigarettes, pipes, or waterpipes)
  • You are able to give your own consent to participate, including a separate consent related to HIV

Volunteers with Lung Disease (Group 1.2):

  • You are 18 years of age or older, of any sex, race, or background
  • You have lung disease or lung disease symptoms, confirmed by at least one of the following: symptoms, a chest X-ray, breathing tests, a lung biopsy, a family history of lung disease, or a condition known to affect the lungs
  • You are able to give your own consent to participate, including a separate consent related to HIV

Additional requirement for Cystic Fibrosis (CF) participants:

  • You carry two copies of a specific CF gene change called ΔF508, and your lung function is at least 50% of the expected level (confirm with trial site)

Clinical Patients (Groups 2 & 3):

  • You are 18 years of age or older and are being seen at one of the participating clinics
  • You have evidence of lung disease through symptoms, imaging, breathing tests, biopsy, family history, a related organ condition, or a higher-than-normal level of certain immune cells in your blood called eosinophils (5% or more)
  • You are willing and able to give your own consent to participate

Who may not be able to join:

Healthy Volunteers (Group 1.1):

  • You have a history of chronic lung disease (such as asthma) or have had a lung illness in the past three months
  • You are not considered to be in good overall health by the study doctor
  • You are allergic to atropine, any local anesthetic, pilocarpine, isoproterenol, terbutaline, or aminophylline
  • You are currently pregnant or breastfeeding

Volunteers with Lung Disease (Group 1.2):

  • You are allergic to any of the following medications: xylocaine, lidocaine, versed, valium, atropine, pilocarpine, isoproterenol, terbutaline, aminophylline, or any local anesthetic
  • The study doctor believes it would not be safe for you to undergo the study procedure (a bronchoscopy, a procedure to look inside the airways)
  • You are currently pregnant or breastfeeding

Additional exclusion for CF participants:

  • You have had a worsening of your CF lung symptoms within the past 8 weeks

Clinical Patients (Groups 2 & 3):

  • You do not wish to give your consent to take part in the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ronald G. Crystal, M.D., Weill Medical College of Cornell University

Phone: 12127460284

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
29 August 2012
Est. completion
1 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Establishing normal ranges for various parameters

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov