Phase 2 Brain Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have previously been diagnosed with cancer (confirmed by tissue testing), except for small cell lung cancer, lymphoma, or germ cell cancers
• People whose MRI scan shows between 1 and 4 tumours that have spread to the brain, with at least one tumour measuring more than 20mm and no larger than 50mm at its widest point, and where surgery and a targeted radiation treatment called SRS are considered appropriate options
• People who have previously had SRS treatment on other brain tumours (not the one being targeted in this trial)
• People who score 70 or above on the Karnofsky performance scale, which is a medical measure of a person's ability to carry out daily activities (confirm with trial site)

Who may not be able to join:

• People considered medically unfit to have surgery to remove a brain tumour
• People who have previously had whole brain radiation therapy
• People who are unable to have an MRI scan for any medical reason
• People who have a physical or mental condition that would prevent them from taking part in study activities
• People who are unable or unwilling to attend all required follow-up appointments
• People whose treatment planning shows that the optic nerve or the area where the optic nerves cross cannot be kept to a radiation dose of 10 Gray or less
• People whose tumour is located in the brainstem
• People whose scans or cell tests show that the cancer has spread to the lining of the brain or spinal cord

Important: Always verify eligibility with the trial site directly before applying.