Phase 2 Lupus Trial, Terminated NCT01930890 Sponsor: Biogen Condition: Lupus
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT01930890) enrolled 87 people in total across four groups. All participants had previously taken part in an earlier related study and continued into this follow-on phase receiving either a lower dose (3 mg/kg) or a higher dose (20 mg/kg) of the investigational medicine BIIB023, or had switched to one of those doses after previously receiving a dummy treatment (placebo). The trial's main focus was on tracking and counting any unwanted medical events — called adverse events (AEs) — and any serious adverse events (SAEs), which are more severe medical occurrences such as hospitalisation or life-threatening events. The reported data shows that across the four groups, the number of participants who experienced any adverse event ranged from 4 out of 14 people in the placebo-then-lower-dose group, up to 23 out of 33 people in the group who received the lower dose throughout both studies. For serious adverse events, the numbers reported were 2, 12, 3, and 6 participants across the four groups respectively. Deaths were reported for 0, 4, 1, and 3 participants across the groups. Regarding people who stopped treatment or left the study because of an adverse event, the reported data shows that most groups recorded zero such participants, with 2 people in the ongoing lower-dose group and 1 person in the ongoing higher-dose group recorded as having done so. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 2 Lupus Trial, Terminated

NCT01930890
Terminated Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must have completed Week 52 of a previous related study called Study 211LE201 (NCT01499355) without stopping your assigned treatment (either the study drug or placebo).
  • If you are someone who could become pregnant, you must be willing and able to use effective birth control throughout the study and for 6 months after your last dose of the study treatment.

Who may not be able to join:

  • If your health has changed significantly since the previous study — including new medical conditions or abnormal test results — the trial doctor may decide you are no longer suitable to participate.
  • If you stopped taking the study drug or placebo before reaching Week 52 in the previous related study, you would not be eligible.
  • You cannot join if you are currently pregnant, breastfeeding, or planning to become pregnant during the study.
  • If you are unwilling or unable to follow the study's requirements, or if any physical, mental, or social condition might make it difficult for you to do so, you may not be eligible.
  • The trial doctor or the study sponsor may decide you are not suitable for the trial for other reasons not specifically listed here (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Medical Director, Biogen

Australian sites

Research Site, Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Terminated
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
1 November 2013
Est. completion
1 January 2016

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇧🇪 Belgium 🇧🇷 Brazil 🇨🇴 Colombia 🇫🇷 France Hong Kong 🇭🇺 Hungary 🇮🇹 Italy 🇲🇾 Malaysia 🇲🇽 Mexico 🇵🇪 Peru 🇵🇭 Philippines 🇵🇱 Poland 🇷🇺 Russia 🇰🇷 South Korea 🇪🇸 Spain 🇹🇭 Thailand 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Number of Participants Experiencing Adverse Events (AEs) and Serious Adverse Events (SAEs); Number of Participants Who Discontinued Study Treatment or Withdrew From Study Due to an AE

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov