Phase 2 Leukaemia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with Fanconi anemia.
- People who have one of the following blood-related conditions: (1) Severe Aplastic Anemia (very low bone marrow activity) or a severe drop in one type of blood cell, along with very low platelet counts, very low white blood cell counts, or very low red blood cell counts (or dependence on blood transfusions); (2) Myelodysplastic Syndrome (MDS), a condition where the bone marrow doesn't produce enough healthy blood cells; or (3) Acute Myelogenous Leukemia (a type of blood cancer), whether untreated, in remission, or with disease that has returned or not responded to treatment.
- People whose bone marrow donor is either an unrelated donor who is a close tissue-type (HLA) match, or a related donor who is a tissue-type match — but not a fully matched sibling.
- People of any gender or ethnic background.
- People with a general health and activity level score above 70% on standard medical performance scales (confirm with trial site).
- People whose heart is functioning well enough — either no symptoms, or test results showing the heart is pumping adequately (confirm with trial site for specific measurements).
- People whose liver enzyme levels and bilirubin (a liver marker) are within acceptable ranges (confirm with trial site for specific measurements).
- People whose kidney function is within acceptable ranges based on blood tests or kidney filtration rate (confirm with trial site for specific measurements).
- People whose lungs are functioning well enough — either no symptoms, or lung capacity test results above a minimum level (confirm with trial site).
- People who are willing to take part as a research participant and sign a consent form.
- Female patients and female donors who are not pregnant or breastfeeding at the time of signing consent, and who agree to pregnancy testing before the transplant and to avoiding pregnancy during the study.
Who may not be able to join:
- People whose leukemia has spread to the central nervous system (brain and spinal cord).
- Female patients who are pregnant or breastfeeding.
- People who have an active infection (viral, bacterial, or fungal) that is not under control.
- People who test positive for HIV-I/II or HTLV-I/II (certain viral infections).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Parinda Mehta, MD, CCHMC
Phone: (513)803-1102
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Graft Failure or Rejection
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.