Cystic Fibrosis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been newly diagnosed with Cystic Fibrosis (CF), confirmed by at least one of three accepted methods: a sweat chloride test result of 60 or above, two CF-causing gene changes, or specific electrical measurements in the nose or rectum that are typical of CF.
• Children diagnosed early (called "Early Diagnosed"): those identified with CF through newborn screening or for other reasons (such as family history, prenatal testing, or a bowel blockage at birth) within the first 4 months of life, with an original diagnosis date after January 1st, 2006.
• Children diagnosed later (called "Late Diagnosed"): those identified with CF after 4 months of age due to symptoms showing up, with an original diagnosis date after January 1st, 2006.

Who may not be able to join:

• Children or parents who do not wish to participate, or who have withdrawn from the study.
• Cases where the CF diagnosis is uncertain.
• Babies born before 30 weeks of pregnancy.
• Children who required a longer period of breathing support through a machine (mechanical ventilation) in their first 3 months of life.
• Children who have a significant health condition other than CF that could affect their ability to complete the full study.
• Children who have had major surgery before joining, except surgery related to a bowel blockage (meconium ileus) or bowel narrowing at birth.
• Children who have a major problem with an organ other than those already affected by CF (such as the pancreas or liver).
• Children with physical findings that the study doctor believes would affect their safety or the quality of the study results.
• Children who have a long-term lung condition other than CF, such as a condition called bronchopulmonary dysplasia.
• Children who have had a bad reaction to sedation medication in the past, or who are known to have claustrophobia (fear of enclosed spaces).
• Note: Some study procedures involving sedation may be delayed — rather than the child being excluded entirely — if the child has a significant airway blockage (such as severely floppy airways, very enlarged tonsils, heavy snoring, or diagnosed sleep apnoea), or has severe and persistent vomiting related to reflux that does not improve with treatment (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.