Rare disease

Cystic Fibrosis

Clinical trials recruiting in Australia for Cystic Fibrosis, a rare disease, as the public registries list them.

Also called: CF; Mucoviscidosis; Cystic fibrosis of the pancreas; Fibrocystic disease of the pancreas

Sources: ClinicalTrials.gov, MedlinePlus, Orphanet Checked: 11 October 2026 Not medical advice

At a glance

3 trials recruiting in Australia

187 trials recruiting overseas

1-9 / 1 000 000 (Point prevalence, China, Validated) prevalence

All ages age of onset

11 October 2026 date last checked

Trials in Australia

This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.

  • Recruiting Phase 1

    Phase 1 study for people with Cystic Fibrosis

    Where
    • Canberra Hospital, Canberra (ACT) — Recruiting
    • Westmead Hospital, Westmead (NSW) — Recruiting
    • The Prince Charles Hospital, Brisbane (QLD) — Recruiting
    • Monash Medical Centre, Clayton (VIC) — Recruiting
    Who can join Age 16 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Accepted.
    Sponsor Cystetic Medicines, Inc.
    Timeline
    Started 21 March 2023 Today 16 October 2026 Estimated completion 1 December 2025

    Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.

    NCT05802264 · Checked 11 October 2026

  • By invitation Phase 3

    Phase 3 study for people with Cystic Fibrosis

    Where

    No Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.

    • The Kids Research Institute Australia, Nedlands — this site's status is not stated on the record
    • Women's & Children's Hospital, North Adelaide — this site's status is not stated on the record
    • The Royal Children's Hospital Melbourne, Parkville — this site's status is not stated on the record
    • Children's Health Queensland Hospital and Health Service, South Brisbane — this site's status is not stated on the record
    Who can join Age 1 Year and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Vertex Pharmaceuticals Incorporated
    Timeline
    Started 11 August 2023 Today 16 October 2026 Estimated completion 30 July 2029

    NCT05844449 · Checked 11 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Cystic Fibrosis

    Where
    • The Prince Charles Hospital, Queensland — Recruiting
    • Westmead Hospital, Westmead — Recruiting
    Who can join Age 18 Years to 85 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor CSL Behring
    Timeline
    Started 3 September 2025 Today 16 October 2026 Estimated completion 28 February 2028

    NCT07048262 · Checked 11 October 2026

Trials overseas

187 trials for this disease are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.

These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.

Trials not shown here

Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.

Key facts

Inheritance Autosomal recessive
Genes SERPINA1, CFTR, TGFB1, GCLC, MIF, HFE, SLC11A1, DCTN4, CLCA4, STX1A, KCNN4, EDNRA, SLC9A3, HMOX1, SLC6A14, SLC26A9, CEACAM3, CEACAM6, GSTM3
Prevalence 1-9 / 1 000 000 (Point prevalence, China, Validated)
Age of onset All ages

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com).

About Cystic Fibrosis

The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.

Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands. It affects mostly your lungs, pancreas, liver, intestines, sinuses, and sex organs. CF causes your mucus to be thick and sticky. The mucus clogs the lungs, causing breathing problems and making it easy for bacteria to grow. This can lead to repeated lung infections and lung damage. The symptoms and severity of CF can vary. Some people have serious problems from birth. Others have a milder version of the disease that doesn't show up until they are teens or young adults. Sometimes you will have few symptoms, but later you may have more symptoms. CF is diagnosed through various tests, such as gene, blood, and sweat tests. There is no cure for CF, but treatments have improved greatly in recent years. In the past, most deaths from CF were in children and teenagers. Today, with improved treatments, some people who have CF are living into their forties, fifties, or older. Treatments may include chest physical therapy, nutritional and respiratory therapies, medicines, and exercise. NIH: National Heart, Lung, and Blood Institute

US source; availability in Australia may differ.

Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.

Sources and dates

  • ClinicalTrials.gov – trial records, statuses and site lists
  • MedlinePlus – the About text above, reproduced exactly
  • Orphanet / Orphadata – prevalence, age of onset, inheritance, genes and alternative names, used under CC BY 4.0
  • ClinicalTrials.gov processing date: 29 April 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Orphanet citation

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com). Accessed 20 September 2026.

ORPHA:586

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