Rare disease
Neuroblastoma
Clinical trials recruiting in Australia for Neuroblastoma, a rare disease, as the public registries list them.
Also called: NB
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At a glance
4 trials recruiting in Australia
122 trials recruiting overseas
1-5 / 10 000 (Point prevalence, Europe, Validated) prevalence
Adolescent; Antenatal; Childhood; Infancy; Neonatal age of onset
15 October 2026 date last checked
Trials in Australia
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Phase 3
Phase 3 study for people with Neuroblastoma
Where- Sydney children Hospital, Sydney (NSW) — Recruiting
- Children's Cancer Centre, Monash Children's Hospital, Clayton (VIC) — Recruiting
- Oncology/Haematology Department, Perth Children's Hospital, Nedlands (WA) — Suspended
- Children's Cancer & Haematology Services, John Hunter Children's Hospital, New Lambton Heights (NSW) — Recruiting
- Australian and New Zealand Children's Hematology/oncology Group, Sydney (NSW) — Active not recruiting
- sydney children Hospital, Sydney (NSW) — Recruiting
- Cancer Centre for Children, The Children's Hospital, Westmead (NSW) — Suspended
Who can join Age Up to 21 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Gustave Roussy, Cancer Campus, Grand ParisTimelineStarted 5 November 2019 Today 16 October 2026 Estimated completion 1 November 2026NCT04221035 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Neuroblastoma
Where- Sydney Children's Hospital, Randwick (NSW) — Recruiting
- The Children's Hospital at Westmead, Westmead (NSW) — Recruiting
- Queensland Children's Hospital, South Brisbane (QLD) — Recruiting
- Royal Children's Hospital, Parkville (VIC) — Recruiting
- Perth Children's Hospital, Perth (WA) — Recruiting
Who can join Age Up to 30 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor National Cancer Institute (NCI)TimelineStarted 19 April 2024 Today 16 October 2026 Estimated completion 31 December 2029NCT06172296 · Checked 15 October 2026
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Recruiting Phase 2
Phase 2 study for people with Neuroblastoma
Where- Sydney Children's Hospital ( Site 1997), Randwick (NSW) — Recruiting
- Queensland Children's Hospital-Oncology & Haematology ( Site 1996), Brisbane (QLD) — Recruiting
- Royal Children's Hospital-Children's Cancer Centre ( Site 1994), Melbourne (VIC) — Recruiting
Who can join Age 6 Months to 25 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Merck Sharp & Dohme LLCTimelineStarted 16 August 2024 Today 16 October 2026 Estimated completion 31 March 2029NCT06395103 · Checked 13 October 2026
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Recruiting Phase 2
Phase 2 study for people with Neuroblastoma
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Sydney Children's Hospital (SCH), Sydney — Not yet recruiting
Who can join Age 1 Year and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor University of BirminghamTimelineStarted 11 November 2024 Today 16 October 2026 Estimated completion 31 December 2030NCT07334301 · Checked 11 October 2026
Trials overseas
122 trials for this disease are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
Trials not shown here
Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Key facts
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com).
About Neuroblastoma
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
What is neuroblastoma? Neuroblastoma is a type of cancer that forms in nerve cells called neuroblasts. Neuroblasts are immature nerve tissue. They normally turn into working nerve cells. But in neuroblastoma, they form a tumor. Neuroblastoma usually begins in the adrenal glands. You have two adrenal glands, one on top of each kidney. The adrenal glands make important hormones that help control heart rate, blood pressure, blood glucose (blood sugar), and the way the body reacts to stress. Neuroblastoma may also begin in the neck, chest or spinal cord. What causes neuroblastoma? Neuroblastoma is caused by changes in your genes. Gene changes also called gene variants or mutations. In most cases, the cause of the mutation is unknown. In some other cases, the mutation is passed from the parent to the child. What are the symptoms of neuroblastoma? Neuroblastoma often begins in early childhood. Sometimes it begins before a child is born.The most common symptoms are caused by the tumor pressing on nearby tissues as it grows or by cancer spreading to the bone.They include: - A lump in the abdomen, neck, or chest - Bulging eyes - Dark circles around the eyes - Bone pain - Swollen stomach and trouble breathing in babies - Painless, bluish lumps under the skin in babies - Weakness or paralysis (loss of ability to move a body part) How is neuroblastoma diagnosed? To diagnose neuroblastoma, your child's health care provider will do various tests and procedures, which may include: - A medical history. - A neurological exam. - Imaging tests, such as x-rays, a CT scan, an ultrasound, an MRI, or an MIBG scan. In an MIBG scan, a small amount of a radioactive substance is injected into a vein. It travels through the bloodstream and attaches itself to any neuroblastoma cells. A scanner detects the cells. - Blood and urine tests. - Biopsy, in which a sample of tissue is removed and examined under a microscope. - Bone marrow aspiration and biopsy, in which bone marrow, blood, and a small piece of bone are removed for testing. What are the treatments for neuroblastoma? The treatments for neuroblastoma include: - Observation, also called watchful waiting, is where the health care provider does not give any treatments until your child's signs or symptoms appear or change. - Surgery - Radiation therapy. - Chemotherapy. - High-dose chemotherapy and radiation therapy with stem cell rescue. Your child will get high doses of chemotherapy and radiation. This kills the cancer cells, but it also kills healthy cells. So your child will get a stem cell transplant, usually of his or her own cells collected earlier. This helps to replace the healthy cells that were lost. - Iodine 131-MIBG therapy, a treatment with radioactive iodine. The radioactive iodine collects in neuroblastoma cells and kills them with the radiation that is given off. - Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells. NIH: National Cancer Institute
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- Orphanet / Orphadata – prevalence, age of onset, inheritance, genes and alternative names, used under CC BY 4.0
- ClinicalTrials.gov processing date: 14 October 2026.
- This page last checked by Voxsanity: 15 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Orphanet citation
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com). Accessed 20 September 2026.
Neuroblastoma is one of the rare diseases tracked on the Voxsanity rare disease hub, where you can compare it with every other rare condition we follow and filter trials by country.
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