Phase 3 Muscular Dystrophy Trial, Completed NCT02285062 Sponsor: Celgene Condition: Muscular Dystrophy
Back to Muscular Dystrophy

Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT02285062) enrolled 570 people with lymphoma, split into two groups of 285. One group received a drug called lenalidomide combined with a standard chemotherapy regimen known as R-CHOP (referred to as R²-CHOP), while the other group received a dummy pill (placebo) combined with the same R-CHOP chemotherapy. The trial was primarily measuring how long participants went without their disease getting worse or dying — a measure called "progression-free survival." It also tracked a number of secondary measures, including overall survival, how long people remained free of key negative events, how many achieved a complete response (where scans showed no detectable sign of disease), and how many had any measurable response to treatment. The reported data shows that for the primary outcome — progression-free survival — as well as for overall survival, event-free survival, and duration of complete response, the values were recorded as "NA" (not available) in the submitted results. This means those particular figures were not reported in the structured data submitted to ClinicalTrials.gov, so no numbers for those outcomes can be described here. For the secondary outcomes where numbers were provided, the reported data shows that 69.1% of participants in the lenalidomide plus R-CHOP group and 64.9% in the placebo plus R-CHOP group achieved a complete response — meaning scans showed no detectable sign of their lymphoma at the time of assessment. For any measurable response (either complete or partial shrinkage of the lymphoma), the reported rate was 90.9% in both groups. It is worth noting that more participants left the treatment period early in the lenalidomide group (72 people) compared with the placebo group (44 people), though the reasons for this are not detailed in the structured data provided. The reported data shows only what was measured and counted at the time of the data cut-off, and the missing figures for several key outcomes mean a complete picture is not available from this submission alone. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Muscular Dystrophy Trial, Completed

NCT02285062
Completed Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been confirmed by a tissue biopsy to have a specific type of lymphoma called Diffuse Large B-Cell Lymphoma (Activated B-Cell type)
  • You have been recently diagnosed with this lymphoma and have not yet received any treatment for it
  • Your lymphoma can be seen and measured on a CT or MRI scan
  • You are generally able to carry out daily activities with little to no limitation (your doctor will assess this using a standard scale)
  • You are between 18 and 80 years old; if you are over 80, you may still be considered if you are in good general health and your doctor agrees

Who may not be able to join:

  • You have a different type of lymphoma other than Diffuse Large B-Cell Lymphoma
  • You have had another type of cancer in the past, unless you have been cancer-free for 5 or more years
  • You have HIV, Hepatitis B, or Hepatitis C, or have tested positive for any of these infections
  • You have a heart condition where your heart is not pumping efficiently enough (below 45%), or you have moderate-to-severe nerve damage causing weakness or numbness (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Australian sites

Local Institution - 004, Albury, New South Wales
Local Institution - 008, Clayton, Victoria
Local Institution - 002, Geelong, Victoria
Local Institution - 003, Frankston,

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Completed
Phase
Phase 3
Sponsor
Celgene
Registry
ClinicalTrials.gov
Start date
17 February 2015
Est. completion
15 March 2019

Where this trial is recruiting

🇦🇺 Australia 🇧🇪 Belgium 🇨🇦 Canada 🇨🇳 China 🇨🇿 Czechia 🇫🇷 France 🇮🇪 Ireland 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan 🇳🇱 Netherlands 🇳🇿 New Zealand 🇵🇹 Portugal Puerto Rico 🇷🇺 Russia 🇰🇷 South Korea 🇪🇸 Spain 🇨🇭 Switzerland 🇹🇼 Taiwan Turkey (Türkiye) 🇺🇸 United States

4 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Kaplan-Meier Estimate of Progression Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov