Phase 2 Muscular Dystrophy Trial, Recruiting NCT06138743 Sponsor: Arrowhead Pharmaceuticals Condition: Muscular Dystrophy
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Phase 2 Muscular Dystrophy Trial, Recruiting

NCT06138743
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Myotonic Dystrophy Type 1 (DM1) confirmed by genetic testing
  • A doctor has observed signs of DM1, including noticeable muscle stiffness (myotonia)
  • Your DM1 symptoms first appeared after the age of 12
  • You are able to walk at least 10 meters (about 33 feet) on your own at the time of your screening appointment
  • If you are able to have children, you must agree to use highly effective birth control plus a condom throughout the study and for at least 90 days after it ends, and agree not to donate sperm or eggs during this time

Who may not be able to join:

  • You have diabetes that is not well managed or controlled
  • You have been diagnosed with the congenital (present-from-birth) form of DM1
  • You have high blood pressure that is not well controlled
  • You have had a biopsy of a specific lower leg muscle (tibialis anterior) in the past 3 months, or plan to have one during the study
  • You have a significant heart, liver, or kidney condition
  • You tested positive for HIV at your screening appointment
  • You tested positive for Hepatitis B or Hepatitis C at your screening appointment
  • You have epilepsy that is untreated or not well controlled
  • You have taken medication specifically for muscle stiffness (myotonia) recently, within a timeframe based on how long that medication stays in your body (confirm with trial site)
  • Your blood clotting test results were abnormal at your screening appointment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 626-304-3400

Australian sites

Research Site, Liverpool, New South Wales
Research Site, Birtinya, Queensland
Research Site, Herston, Queensland
Research Site, Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Arrowhead Pharmaceuticals
Registry
ClinicalTrials.gov
Start date
4 March 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇦🇺 Australia 🇳🇿 New Zealand 🇹🇼 Taiwan 🇹🇭 Thailand

4 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Number of Participants with Treatment -Emergent Adverse Events (TEAEs) Over Time Through End of Study (EOS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov