Phase 2 Head and Neck Cancer Trial, Recruiting NCT02290145 Sponsor: Shanghai Jiao Tong University School of Medicine Condition: Head and Neck Cancer
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Phase 2 Head and Neck Cancer Trial, Recruiting

NCT02290145
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 75 years old.
  • Both men and women are eligible.
  • People with a reasonable level of general health and ability to carry out daily activities (confirmed by a doctor using a standard health scoring tool).
  • People who have had a tissue sample (biopsy) taken that confirms a specific type of mouth cancer called squamous cell carcinoma, affecting areas such as the tongue, gums, cheek lining, floor of the mouth, roof of the mouth, or the area behind the back teeth.
  • People whose cancer tissue shows a high level of a particular protein called Cyclin D1.
  • People whose cancer is at an advanced but not yet spread stage (Stage III or IVA), where the tumour can still be surgically removed.
  • People whose blood counts meet minimum levels — enough white blood cells, red blood cells, and platelets — as measured by a blood test.
  • People whose liver is functioning adequately, based on standard blood test results.
  • People whose kidneys are functioning adequately, based on standard blood test results.
  • People who are able to give written agreement to take part in the trial.

Who may not be able to join:

  • People whose cancer has spread to distant parts of the body, or who have another active cancer.
  • People who have already had surgery on the main tumour or nearby lymph nodes (a diagnostic biopsy is the exception).
  • People who have previously received radiotherapy or chemotherapy.
  • People who have had another cancer diagnosis within the past 5 years.
  • People with serious ongoing health conditions — such as severe heart or lung disease — that would make it unsafe to receive the trial treatment.
  • People who do not have the legal capacity to give informed consent.
  • People whose kidneys are not clearing waste from the blood efficiently enough, based on a specific kidney function measurement.
  • People who are pregnant or breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86 021-23271699

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai Jiao Tong University School of Medicine
Registry
ClinicalTrials.gov
Start date
1 December 2016
Est. completion
1 December 2024

Where this trial is recruiting

🇨🇳 China

Primary endpoints

overall survival rate as a measure by the numbers of living patients

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov