Phase 2 study for people with Head and Neck Cancer

Recruiting Phase 2

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 2
Sponsor Centre hospitalier de l'Université de Montréal (CHUM)
Registry number NCT04901234
Started 30 July 2021 Today 16 October 2026 Estimated completion 1 December 2026

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Austin Health Melbourne Australia Not yet recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 120

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Age ≥18 years

* Ability to provide written informed consent.

* Stage T3-T4N0-3 as per AJCC 8th edition

* Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

* Biopsy proven diagnosis of squamous cell carcinoma of the oropharynx.

* Planned for curative radiotherapy +/- chemotherapy

* For females of child-bearing age, a negative pregnancy test

* Patients treated with induction chemotherapy can be included if they have residual tumor in place.

Exclusion Criteria:

* Previous irradiation of the head and neck (HNC) region, excluding superficial radiation therapy for non-melanomatous skin cancer

* Previous surgery of the HNC region (except for incisional or excisional biopsies)

* Pregnancy or breastfeeding

* Connective tissue disease

* Any medical condition that could, in the opinion of the investigator, prevent follow-up after radiotherapy.

* Patients with contra-indications to MRI will be excluded.

Dates on the record

Started 30 July 2021
Estimated completion 1 December 2026
Registry last updated 24 August 2026
Checked by Voxsanity 11 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 24 August 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.