Friedreich Ataxia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

For people with Friedreich's Ataxia (FRDA):

Who might be able to join this trial:

• You are male or female, between 12 and 50 years old
• You are willing and able to give your consent to participate (teenagers will need to give their own agreement, and a parent must also give consent)
• You have a confirmed diagnosis of Friedreich's Ataxia, based on your symptoms and genetic test results
• Your heart's pumping strength (measured by an ultrasound of the heart) is above a certain level — if you haven't had this test recently, it will be done before you join

Who may not be able to join:

• You have signs or symptoms of heart failure
• You have moderate to severe irregular heart rhythms
• You have a history of chest pain caused by reduced blood flow to the heart (angina)
• You have an implanted pacemaker, defibrillator, or any other device that would prevent you from having an MRI scan
• You are on dialysis, have significantly reduced kidney function, or have a sudden kidney injury (if a recent kidney test isn't available, one will be done before your MRI)
• You are pregnant
• You have taken part in a study involving an experimental drug or device recently, or are currently enrolled in one
• You are unable to have a cardiac MRI scan using a special dye (contrast), or you have claustrophobia (fear of enclosed spaces)
• You have been diagnosed with Type 1 or Type 2 Diabetes
• You have any other condition or health issue that the study doctor believes would make it unsafe or unsuitable for you to participate (confirm with trial site)

For healthy volunteers (normal controls):

Who might be able to join this trial:

• You are male or female, between 12 and 30 years old
• You are willing and able to give your consent to participate (teenagers will need to give their own agreement, and a parent must also give consent)
• Your age, gender, and ethnicity are similar to those of participants in the Friedreich's Ataxia group
• You are able to complete the various heart assessment tests involved in the study
• Your heart's pumping strength (measured by an ultrasound of the heart) is above a certain level — if you haven't had this test recently, it will be done before you join

Who may not be able to join:

• The study doctor does not consider you to be in good overall health
• You have signs or symptoms of heart failure
• You have moderate to severe irregular heart rhythms
• You have a history of chest pain caused by reduced blood flow to the heart (angina)
• You have an implanted pacemaker, defibrillator, or any other device that would prevent you from having an MRI scan
• You are on dialysis, have significantly reduced kidney function, or have a sudden kidney injury (if a recent kidney test isn't available, one will be done before your MRI)
• You are pregnant or breastfeeding
• You have taken part in a study involving an experimental drug or device recently, or are currently enrolled in one
• You are unable to sit upright with back support
• You are unable to have a cardiac MRI scan using a special dye (contrast), or you have claustrophobia (fear of enclosed spaces)
• You are unable to take part in exercise tests
• You have been diagnosed with Type 1 or Type 2 Diabetes
• You have any other condition or health issue that the study doctor believes would make it unsafe or unsuitable for you to participate (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.