Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

This trial has three groups (called cohorts). Criteria differ slightly between them:

Cohort 1 – General advanced lung cancer group:

• People who have been diagnosed with advanced non-small-cell lung cancer (stage IIIB or IV), regardless of any specific genetic mutation status
• People who are being enrolled at the time of their initial diagnosis
• People who have had a tumour tissue sample (biopsy) taken, either at the trial hospital (Centre Léon Bérard) or elsewhere, with a written pathology report available
• People aged 18 or older
• People who have health insurance coverage
• People who have signed a consent form agreeing to participate

Cohort 2 – Advanced lung cancer with specific genetic changes:

• People who have been diagnosed with advanced non-small-cell lung cancer (stage IIIB or IV) that has one of these specific genetic changes: EGFR, BRAF, or HER2 mutations; ALK or ROS1 gene rearrangements; MET gene amplification; or RET rearrangement
• People who are being enrolled at the time of their initial diagnosis
• People who have had a tumour tissue sample (biopsy) taken, either at the trial hospital or elsewhere, with a written pathology report available
• People aged 18 or older
• People who have health insurance coverage
• People who have signed a consent form agreeing to participate

Cohort 3 – Advanced lung cancer starting immunotherapy:

• People who have been diagnosed with advanced non-small-cell lung cancer (stage IIIB or IV), regardless of genetic mutation status or a marker called PD-L1
• People who are being enrolled at the point when they are starting immunotherapy treatment (either as their first or second treatment)
• People who have had a tumour tissue sample (biopsy) taken, either at the trial hospital or elsewhere, with a written pathology report available
• People aged 18 or older
• People who have health insurance coverage
• People who have signed a consent form agreeing to participate

Who may not be able to join:

• (Cohort 1) People who have already started cancer treatment before a liquid biopsy (a special blood test) has been taken
• (Cohort 3) People who have already started immunotherapy treatment before a liquid biopsy (a special blood test) has been taken

Important: Always verify eligibility with the trial site directly before applying.