Phase 4 Uveitis Trial, Terminated NCT02769702 Sponsor: Washington University School of Medicine Condition: Uveitis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial looked at a medication called Acthar (given at a dose of 80 IU) in people with uveitis — an inflammatory condition affecting the eye. The trial enrolled just 2 participants, and both of them completed the study. The main thing being measured was the level of cells in the front chamber of the eye (a sign of eye inflammation), rated on a scale from 0 to 4, where a higher number means more cells and more inflammation. A secondary measure looked at the amount of protein in the front chamber of the eye, also rated on the same 0 to 4 scale. The reported data shows that for the primary measure — the cell count in the front of the eye — the change from the starting point (baseline) was reported as 0.5 at one time point and 1.25 at another. These numbers represent how much the score shifted during the trial on the 0-to-4 scale. For the secondary measure — protein levels in the front of the eye — the reported data shows one time point value was not reported (listed as not available), and the other time point showed a change of 1.0 on the same scale. Because only 2 people took part in this trial, the numbers reflect a very small group of participants. It is worth noting that with only 2 participants, the reported figures are based on an extremely small sample, and the results should be understood in that context. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 4 Uveitis Trial, Terminated

NCT02769702
Terminated Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have active inflammation at the front of your eye (called anterior uveitis) that is currently being treated with steroid tablets and/or steroid eye drops.

Who may not be able to join:

  • Your diabetes is not well controlled.
  • Your glaucoma (a condition causing increased pressure in the eye) is not well controlled.
  • You have HIV or another infection where steroid treatment would not be safe.
  • You have a medical reason why you cannot take the study drug ACTHAR (confirm with trial site).
  • You have scleroderma (a condition that hardens and tightens the skin and connective tissues).
  • You have osteoporosis (weak or brittle bones).
  • You have a herpes simplex infection affecting your eye.
  • You have a fungal infection affecting your whole body.
  • You have had surgery recently (confirm with trial site for specific timeframe).
  • Your high blood pressure is not well controlled.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

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Trial details

Status
Terminated
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
1 June 2016
Est. completion
6 January 2017

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change From Baseline in Eye With Uveitis of Anterior Chamber Cellularity Graded From 0-4 on a Likert Scale Determined by Slit Lamp Examination

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov