Brain Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Cohort 1 – Newly diagnosed brain tumor (up to 30 participants)

• Children and young people aged 4 to 18 years old
• Recently diagnosed with a primary brain tumor of any type or location
• Expected to live for at least one year
• Able to understand the study and willing to agree to take part, with a parent or guardian's agreement if required

Cohort 2 – Posterior fossa brain tumor (up to 150 participants)

• Children and young people aged 4 to 18 years old
• Previously diagnosed with a brain tumor in the lower back part of the brain (called the posterior fossa), whether currently receiving treatment or having already finished treatment
• Expected to live for at least one year
• Able to understand the study and willing to agree to take part, with a parent or guardian's agreement if required

Cohort 3 – Posterior fossa syndrome (up to 20 participants)

• Children and young people aged 4 to 18 years old
• Previously diagnosed with a brain tumor in the lower back part of the brain (posterior fossa)
• Diagnosed with a condition called posterior fossa syndrome after surgery (a condition that can affect speech, movement, and behaviour following certain brain surgeries)
• Unable to complete a specific set of computer-based tests called the NIH Toolbox
• Expected to live for at least one year
• Able to understand the study and willing to agree to take part, with a parent or guardian's agreement if required

Cohort 4 – Long-term follow-up (up to 50 participants)

• People aged 12 to 30 years old
• Diagnosed with a brain tumor more than 3 years before joining the study
• Expected to live for at least one year
• Able to complete a 1-hour MRI scan without needing sedation (medication to make someone drowsy or sleep)
• Able to understand the study and willing to agree to take part, with a parent or guardian's agreement if required

Who may not be able to join:

Cohorts 1 and 2

• People whose vision is impaired to the point where completing computer-based tests would not be possible
• People who are unable to have an MRI scan for medical reasons, such as having a cardiac pacemaker (a device implanted in the chest to help the heart beat)
• People who have a programmable shunt (a device implanted in the brain to drain fluid, with adjustable settings) — this applies to Cohort 1 only

Cohort 3

• People who are unable to have an MRI scan for medical reasons, such as having a cardiac pacemaker

Cohort 4

• People who are unable to have an MRI scan for medical reasons, such as having a cardiac pacemaker
• People who wear dental braces or have a programmable shunt
• People who require sedation in order to undergo an MRI scan

Important: Always verify eligibility with the trial site directly before applying.