Phase 4 Brain Cancer Trial, Recruiting NCT03014687 Sponsor: St. Joseph's Hospital and Medical Center, Phoenix Condition: Brain Cancer
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Phase 4 Brain Cancer Trial, Recruiting

NCT03014687
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are adults (aged 18 to 85) having endoscopic (keyhole, through the nose) surgery to remove a pituitary tumour, specifically a non-functioning adenoma, acromegaly-related tumour, or prolactinoma
  • People who speak English and are able to understand and complete two specific questionnaires used in the study (the ASK Nasal-12 and SNOT-22)
  • People who are free from any physical, mental, or medical condition that the trial investigators consider would make participation unsafe or unsuitable

Who may not be able to join:

  • People who have had a severe allergic reaction (anaphylaxis) to, or cannot tolerate, the study medications
  • People with cirrhosis (serious liver scarring) or hepatitis (liver inflammation)
  • People who have received a solid organ transplant (such as a kidney or heart) or a bone marrow transplant, or who are considered by the investigators to have a weakened immune system
  • People whose kidneys have failed and who are on dialysis
  • People who are unwilling or unable to sign the consent form for the study
  • People who are pregnant
  • People who are currently incarcerated
  • People with Cushing's disease (a condition caused by too much cortisol)
  • People with a Rathke's Cleft cyst or a pituitary cyst
  • People with a history of chronic sinusitis (long-term sinus inflammation)
  • People for whom nasal splints are planned to be used during surgery
  • People for whom a nasal septal flap procedure is planned during surgery
  • People with a currently active sinus infection
  • People who have nasal polyps (soft growths inside the nose)
  • People who have had previous sinus surgery
  • People currently taking antibiotics for another condition (such as a urinary tract infection)
  • People with an immunodeficiency (a condition that weakens the immune system)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Andrew Little, MD, Barrow Brain and Spine

Phone: 602-406-6976

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Registry
ClinicalTrials.gov
Start date
1 July 2017
Est. completion
1 January 2019

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in quality of life from baseline - Anterior Skull Base Nasal Inventory 12 (ASK Nasal-12); Change in quality of life from baseline - Sino-Nasal Outcome Test (SNOT-22)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov