Phase 2 Kidney Cancer Trial, Recruiting NCT03101995 Sponsor: National Institute of Cancerología Condition: Kidney Cancer
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Phase 2 Kidney Cancer Trial, Recruiting

NCT03101995
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who give written consent to take part in the study.
  • Women between 18 and 70 years of age.
  • Women of childbearing age who have a negative blood pregnancy test taken within 14 days before treatment starts, and who agree to use a contraceptive method approved by their doctor during the study and for 12 weeks after treatment ends.
  • Postmenopausal women who have had both ovaries surgically removed, are aged 60 or older, or are under 60 with no periods for at least 12 months and hormone levels that confirm menopause.
  • Women diagnosed with a specific stage of cervical cancer (stage IB2 to IVA), with or without nearby lymph nodes affected (as long as those nodes are smaller than 2 cm).
  • Cancer confirmed by laboratory testing as one of these types: squamous carcinoma, adenosquamous carcinoma, adenocarcinoma, or glassy cell carcinoma.
  • Women who have not had any previous treatment for this cancer and whose health allows them to receive the drug gemcitabine.
  • Cancer that can be measured on CT or MRI scans using standard measurement guidelines.
  • A general health/functioning score of 0 to 3 on the World Health Organization scale (confirm with trial site).
  • Reduced kidney function meeting a specific threshold, measured by a standard kidney function formula (confirm with trial site).
  • Blood counts and liver function results within acceptable ranges, including sufficient haemoglobin, white blood cells, platelets, and liver enzyme levels (a blood transfusion before treatment to reach the required haemoglobin level is permitted).
  • A normal chest X-ray.

Who may not be able to join:

  • People who have had or currently have another cancer, except for certain non-serious skin cancers.
  • People with diabetes and/or high blood pressure that has affected the eyes or caused high levels of protein in the urine.
  • People with an active tuberculosis (TB) infection.
  • People living with HIV.
  • People with a history of Lupus or other rheumatic diseases that have caused kidney damage.
  • People who have an abnormal opening between the bladder and vagina, or between the bladder and rectum, at the time of diagnosis.
  • People with other serious uncontrolled health conditions, including active infections, heart failure, unstable chest pain, irregular heartbeat, uncontrolled diabetes, very difficult to manage high blood pressure, or serious mental illness.
  • People currently taking part in another experimental drug trial.
  • People whose social, family, or location circumstances suggest they may have difficulty following the study requirements.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Lucely C Cetina, MD, M.Sc., National Institute of Cancerología

Phone: +5215554851237

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
National Institute of Cancerología
Registry
ClinicalTrials.gov
Start date
16 January 2018
Est. completion
1 July 2025

Where this trial is recruiting

🇲🇽 Mexico

Primary endpoints

Glomerular Filtration Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov