Kidney Cancer

**Who might be able to join this trial:** - A person who has been confirmed by tissue or cell testing to have kidney cancer (renal cell carcinoma) that contains a "clear-cell" component. - A person whose kidney cancer has been documented as advanced (spread beyond the kidney). - A person who has at least one tumour th...

"Who might be able to join this trial: - You received a kidney transplant at least 1 year ago - Your transplanted kidney is working reasonably well, with good kidney function levels and only a small amount of protein in your urine (confirm with trial site for specific measurements) - You are currently taking a stable c...

**Who might be able to join this trial:** - You have been recently diagnosed with one of these specific kidney-related cancers: focal or diffuse anaplastic Wilms' tumor, clear cell sarcoma of the kidney, malignant rhabdoid tumor (in the kidney or elsewhere in the body), or certain types of renal cell carcinoma (kidney...

**Who might be able to join this trial:** - You have been diagnosed with advanced or spreading kidney cancer (renal cell carcinoma) that has been confirmed by a lab test and contains a specific type called "clear cell" - You are able to provide a preserved tumor tissue sample (either a new biopsy taken during the scre...

**Who might be able to join this trial:** - People who have signed a written consent form agreeing to take part in the trial. - People who are 18 years of age or older at the time of signing the consent form. - People who have between 1 and 5 detectable metastases (areas where cancer has spread) that can be measured u...

**Who might be able to join this trial:** - People who have previously had a solid organ transplant (such as a kidney, liver, heart, lung, pancreas, or small bowel) or a bone marrow/stem cell transplant from a donor. - People who have been diagnosed with a condition called EBV-positive PTLD (a type of lymphoma linked...

**Who might be able to join this trial:** - You are 30 years old or younger at the time of joining the study - You have been newly diagnosed with stages 2, 3, or 4 diffuse anaplastic Wilms tumor (a specific type of kidney cancer), confirmed by a central medical review team - You have a type of kidney cancer called fav...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer (renal cell carcinoma) confirmed by a tissue or cell sample before joining the trial - People whose kidney cancer has spread to nearby lymph nodes and cannot be surgically removed, or has spread to other parts of the body (me...

Who might be able to join this trial: - People who have at least one tumour that can be measured using standard imaging guidelines. - People who are generally able to carry out daily activities with little to no limitation (based on a standard health scoring system called ECOG, with a score of 0 or 1). - For the dose-f...

Who might be able to join this trial: - People who have an advanced or spreading solid tumour that has grown or worsened despite standard treatments, and whose tumour cannot be surgically removed, or who are not suitable for or have chosen not to have standard treatments. - People who have at least one tumour that can...

**Who might be able to join this trial:** - You are between 3 and 29 years old at the time of joining the study - You have been newly diagnosed with a specific type of brain tumor called a germinoma, located in the suprasellar region (near the base of the brain) and/or the pineal region (near the center of the brain),...

**Who might be able to join this trial:** - People who are already enrolled in a related screening study called APEC14B1 and have agreed to its eligibility screening section before joining this trial. - People who are under 30 years old at the time of joining. - People who have been newly diagnosed with Stage I, II, I...

Who might be able to join this trial: - People who are 18 years of age or older. - People who have been diagnosed with a locally advanced, inoperable, or metastatic solid tumour that has been confirmed by laboratory tissue testing, and whose tumour type fits the specific part of the trial they are being considered for...

**Who might be able to join this trial:** - People who have a blood cancer (such as acute myeloid leukemia, myelodysplastic syndrome, certain bone marrow disorders, chronic myelomonocytic leukemia, multiple myeloma, or non-Hodgkin's lymphoma) or a solid tumour (excluding brain tumours called gliomas), where testing ha...

Who might be able to join this trial: - People diagnosed with kidney cancer (specifically clear cell renal cell carcinoma) that cannot be removed by surgery and has either spread to other parts of the body or is advanced locally. - People whose overall health and ability to carry out daily activities meets a certain mi...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have signed and dated a written consent form before any study-related procedures begin - People who have kidney cancer (renal cell carcinoma, or RCC) that has come back, spread to nearby areas, or spread to other parts of...

Who might be able to join this trial: - People who have been diagnosed with advanced kidney cancer (specifically a type called clear cell renal cell carcinoma, with or without certain aggressive features) that cannot be surgically removed and has spread to other parts of the body (Stage IV). - People whose cancer can b...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with kidney cancer (RCC) that has spread or cannot be removed or treated with radiation, confirmed by a tissue or cell sample - You have at least one tumour that can be measured by scans and has not yet been treated -...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer (renal cell carcinoma) that has spread or cannot be removed or cured by surgery or radiation, confirmed by a tissue biopsy or lab test - People with the clear cell type of kidney cancer, or in the early part of the trial (Par...

**Who might be able to join this trial:** - You have been diagnosed with advanced kidney cancer (specifically a type called clear cell renal cell carcinoma) that cannot be removed by surgery, and it has spread to other parts of the body (Stage IV) - Your cancer can be measured using scans, meaning there are visible tu...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with a type of kidney cancer called clear-cell renal cell carcinoma (RCC), confirmed by a lab test on a tissue sample - Your kidney cancer has spread to nearby areas or to other parts of your body - You have at least...

**Who might be able to join this trial:** - You are generally healthy and able to carry out daily activities with little or no limitation (confirm with trial site regarding the specific fitness score required) - Your kidney cancer has been confirmed by a lab test and is either a "clear cell" or "sarcomatoid" type, has...

**Who might be able to join this trial:** - People who have been diagnosed with certain cancers confirmed by laboratory testing, including non-small cell lung cancer, melanoma, bladder or urinary tract cancer, kidney cancer, triple negative breast cancer, uterine cancer, head and neck cancer (Phase 1), or ovarian canc...

Who might be able to join this trial: - People aged 2 years or older, and their biological family members, may be considered for this trial. - All participants (and a parent or guardian for anyone under 18) must sign a consent form showing they understand the study and its risks before anything begins. - People who hav...

Who might be able to join this trial: - People who have been diagnosed with at least one fibrofolliculoma (a specific type of benign skin growth), confirmed by a tissue biopsy. - People who have multiple small skin bumps (without a biopsy confirming fibrofolliculomas) AND either a personal or family history of a collap...

Who might be able to join this trial: - People who are suspected or known to have a condition called Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome (HLRCC), which may be indicated by having skin tumours called leiomyomas along with kidney cancer; or skin leiomyomas along with uterine (womb) leiomyomas (fibroi...

Who might be able to join this trial: - People who are scheduled to have a nephroureterectomy (surgery to remove a kidney and ureter), cystectomy (surgery to remove the bladder), or cystoscopy (a procedure to look inside the bladder), whether newly diagnosed with bladder cancer or being monitored for returning cancer -...

Who might be able to join this trial: - People who are 18 years of age or older - People who are willing to provide data and samples for research purposes - People who are able to understand and are willing to sign a written consent form - People who have been diagnosed with a blood cancer or a solid tumour (including...

**Who might be able to join this trial:** - You have been diagnosed with any type of tumor, cancer, pre-cancerous condition, or are suspected of having a hereditary condition that may lead to cancer (this applies to any age) - You are a blood relative of someone who has been diagnosed with a tumor, cancer, pre-cancero...

**Who might be able to join this trial:** - You have been diagnosed with Stage I kidney cancer (a specific early stage called T1N0M0) where the tumor is no larger than 8 cm, confirmed by MRI or CT scan - You are willing to have at least one small gold marker (called a fiducial) placed in or near the tumor to help guid...

Who might be able to join this trial: **Kidney Cancer Group:** - People aged 18 or older who speak English and have been diagnosed with kidney cancer, or where kidney cancer is suspected **Family Member Group:** - People aged 18 or older who speak English and are a blood relative of someone already enrolled in the ki...

Who might be able to join this trial: - People who have a solid kidney mass of 4cm or smaller that was found by chance during a scan in the last 6 months, and that shows up with contrast (enhancement) on imaging. - People who are 18 years of age or older and are able to read, understand, and sign a consent form. - Peop...

**Who might be able to join this trial:** - Your cancer cannot be surgically removed and must test positive for a specific protein called CD70 at a certain level, based on a lab test of cancer tissue. - Your cancer diagnosis must be confirmed by the NCI Laboratory of Pathology. - You must have already tried at least o...

Who might be able to join this trial: - People who give written consent to take part in the study. - Women between 18 and 70 years of age. - Women of childbearing age who have a negative blood pregnancy test taken within 14 days before treatment starts, and who agree to use a contraceptive method approved by their doct...

Who might be able to join this trial: - People who have been diagnosed with kidney cancer (renal cell carcinoma, or RCC) confirmed by laboratory testing — all types are eligible except pure oncocytoma, collecting duct, medullary, and transitional cell cancer - People who have no visible remaining cancer on a CT scan ta...

Who might be able to join this trial: - Adults who have been diagnosed with kidney cancer - People who have no objection to their personal data being collected and used for this study Who may not be able to join: - There are no stated exclusion criteria for this trial Important: Always verify eligibility with the tri...

**Who might be able to join this trial:** - People who have been diagnosed with stage III, stage IV, or returned (relapsed) cervical cancer, confirmed through tissue testing (biopsy). - People aged 18 to 70 years old. - People who have waited at least 4 weeks since their last chemotherapy or radiation treatment, and a...

**Who might be able to join this trial:** **For people with advanced kidney cancer (aRCC) or advanced bladder/urinary tract cancer (aUBC):** - People of any gender who have advanced kidney cancer or advanced bladder/urinary tract cancer that has spread locally, cannot be removed by surgery, or has spread to other part...

Who might be able to join this trial: - People who have been diagnosed with kidney cancer. Who may not be able to join: - People whose final pathology report did not confirm the presence of cancer (i.e., the tissue examined showed no signs of cancer). - People who are unable to make their own medical decisions or are...

Who might be able to join this trial: - People who are aged 65 years or older - People who have been living in the Nanshan district of Shenzhen for at least 5 years - People who are Chinese Who may not be able to join: - People who have a history of diabetes, heart failure, liver failure, kidney failure, cancer, or ca...

**Who might be able to join this trial:** - You have kidney cancer that cannot be removed by surgery, has spread to nearby areas, or has spread to other parts of the body. - You are currently being treated with a certain type of cancer medication (a TKI, mTOR inhibitor, or immunotherapy) and have developed mouth sores...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of joining the study. - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (RCC) with a specific cell type called "clear cell," confirmed through a tissue sample test. - People whose can...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer that has spread to other parts of the body (metastatic renal tumour) at the time of their first diagnosis - People who have at least one clearly defined, non-calcified spot or growth measuring 3mm or larger — such as a nodule...

Who might be able to join this trial: - People who have a solid kidney mass (either a primary kidney cancer or a cancer that has spread to the kidney) that measures 6cm or smaller and is suitable for a targeted radiation treatment called SABR - People who have been diagnosed with a kidney tumour, either confirmed by a...

Who might be able to join this trial: - You have been diagnosed with Von Hippel-Lindau (VHL) Disease, which is a rare genetic condition that can cause tumors and cysts to grow in various parts of the body Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial...

**Who might be able to join this trial:** - People who are willing and able to sign a written consent form before any study procedures begin. - People aged 18 or older. - People who have been diagnosed with kidney cancer (renal cell carcinoma), confirmed by a tissue sample — both common and less common types are allow...

Who might be able to join this trial: - People who are able to read, understand, and interpret an informed consent form - People who are willing to sign a written consent form agreeing to take part in an active surveillance programme - People who are over 50 years of age - People who have been diagnosed with a single,...

Who might be able to join this trial: - People who are under 30 years of age - People who have been diagnosed with Wilms tumor or clear cell sarcoma of the kidney (a type of kidney cancer) where radiation therapy is considered a standard part of treatment - People whose Wilms tumor is classified as "favorable histology...

Who might be able to join this trial: - People who are already scheduled to have a standard medical procedure to treat or take a tissue sample (biopsy) from the liver or kidney using a technique called ablation or biopsy. Who may not be able to join: - There are no listed reasons that would prevent someone from joinin...

Who might be able to join this trial: - People who have been diagnosed with renal cell carcinoma (a type of kidney cancer) and have already had surgery for it Who may not be able to join: - People who have been diagnosed with renal cell carcinoma but have not had surgery for it Important: Always verify eligibility wi...

**Who might be able to join this trial:** - People who have signed a consent form before any study procedures begin - People who are willing and able to follow the study's procedures and requirements - People aged 18 or older - People who have been diagnosed with metastatic renal cell carcinoma (a type of kidney cance...

Who might be able to join this trial: - Adults over 18 years old who have primary (originating in the liver) or secondary (spread to the liver from elsewhere) liver tumours, or small kidney tumours, where surgery is not possible or cannot fully remove the tumour - People with primary liver cancer who have up to three t...

**Who might be able to join this trial:** - You have a kidney mass (lump or growth on the kidney) that requires surgery to remove part or all of the kidney - You are enrolled in the French social security system - You are willing and able to sign a consent form agreeing to take part *For the control group (comparison...

**Who might be able to join this trial:** - People who have been diagnosed with clear cell renal (kidney) cancer, confirmed by a tissue sample (other cancer cell types mixed in are allowed) - People whose cancer is rated as "good" or "intermediate" risk based on a scoring system called Heng criteria (confirm with tria...

**Who might be able to join this trial:** - People aged 1 year old up to and including 30 years old at the time treatment begins. - People who have been confirmed by tissue testing to have a solid tumour or brain/spinal cancer that has come back or stopped responding to treatment. - People aged 16 and over who score a...

Who might be able to join this trial: - Children who have a Wilms' tumor (a type of kidney cancer) affecting only one kidney - Children who have not received any previous treatment for this tumor - Children whose general health is good enough to allow treatment to go ahead Who may not be able to join: - Children who h...

**Who might be able to join this trial:** - Adults (18 years or older) who are starting cisplatin chemotherapy (at a certain dose) for head/neck or lung cancer at one of the participating adult hospitals. - Children older than 3 months who are starting cisplatin chemotherapy for any type of cancer at one of the partic...

**Who might be able to join this trial:** - People who have chosen to undergo a type of internal radiation treatment (interstitial brachytherapy) as part of their standard care for kidney cancer - People whose kidney cancer has been confirmed by a biopsy - People whose cancer has not spread to nearby lymph nodes, near...

**Who might be able to join this trial:** - You have been diagnosed with a type of kidney cancer called clear cell or non-clear cell renal cell carcinoma (confirmed by a tissue sample/biopsy); people with collecting duct carcinoma cannot join. - Your original kidney tumor is still in place (has not been removed yet)....

**Who might be able to join this trial:** - People diagnosed with Wilms tumor or desmoplastic small round cell tumor (DSRCT), confirmed by a tissue sample either at the time of original diagnosis or at relapse - For the first phase of the trial (Part A): children aged 2 years up to (but not including) 12 years old at...

Who might be able to join this trial: - People who have imaging scans showing known or suspected kidney or bladder/urinary tract cancer that needs to be surgically biopsied or removed. - People aged 18 years or older. - People of any race or ethnic background. - People who are willing and able to read and sign a consen...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are able to understand and agree to sign a consent form, or who have a legal representative, caregiver, or family member who can do this on their behalf - People who have been diagnosed with high-grade upper tract urotheli...

Who might be able to join this trial: - People in Denmark who have metastatic renal cell carcinoma (a type of kidney cancer that has spread to other parts of the body) and are receiving medical treatment for it. Who may not be able to join: - People who have not provided written informed consent (a signed document sho...

Who might be able to join this trial: - You must be 18 years old or older - You must be willing and able to sign a consent form agreeing to take part in the trial - You must have a localized tumor (mass) on the kidney that can be treated with surgery that aims to save as much of the kidney as possible - You must have h...

Who might be able to join this trial: - You have agreed and signed a consent form allowing your samples and personal-information-removed data to be collected, stored, and shared. Who may not be able to join: - You have not signed a consent form agreeing to have your samples and personal-information-removed data collec...

**Who might be able to join this trial:** - You are older than 20 years of age - You have been diagnosed with advanced or metastatic renal cell carcinoma (a type of kidney cancer that has spread or is at an advanced stage) - You are about to start a type of cancer treatment that works through the immune system (called...

**Who might be able to join this trial:** - People aged 1 to 21 years old - People who have a solid tumour that tests positive for a protein called GPC3, confirmed by a laboratory test showing a strong enough level of that protein in the tumour cells - People whose general health and ability to carry out daily activit...

**This trial has two separate groups (Cohort A and Cohort B) with different criteria. Please read both carefully and confirm with the trial site which group may apply.** --- ## Cohort A — Trial combining two drugs (Sacituzumab Govitecan + Enfortumab Vedotin) **Who might be able to join this trial:** - People who hav...

**Who might be able to join this trial:** - You weigh at least 35 kilograms (about 77 pounds). - You are able to carry out basic daily activities and care for yourself, with limited or no restriction due to your illness (confirm with trial site for exact activity level required). - Doctors expect you to live for at le...

**Who might be able to join this trial:** - You have been diagnosed with metastatic clear cell kidney cancer (a specific type of kidney cancer that has spread to other parts of the body). - You are 18 years of age or older. - You are well enough to carry out daily activities, either fully, with minor limitations, or wi...

**Who might be able to join this trial:** - You have been diagnosed with upper urinary tract cancer (in the kidney or ureter) confirmed by a biopsy, and you are scheduled for surgery to remove it with the goal of curing the disease - You are between 18 and 90 years old - Your doctor expects you to live for more than 1...

**Who might be able to join this trial:** - People who are older than 12 months and younger than 30 years old at the time of joining the study. - For the Phase I part: People with a solid tumour (not in the brain or spinal cord) that has come back or stopped responding to treatment, and where a cure is no longer possi...

Who might be able to join this trial: - People who are waiting to start immunotherapy, or a combination of immunotherapy and platinum-based chemotherapy Who may not be able to join: - People who are terminally ill - People who do not wish to sign the consent form agreeing to take part in the trial Important: Always v...

**Who might be able to join this trial:** - People who are able to understand the study, follow its procedures, and give formal written consent before any study activities begin — including keeping to a specific blood-test schedule during the first treatment cycle. - People who have a confirmed cancer diagnosis, which...

**Who might be able to join this trial:** - People who have been newly diagnosed with Wilms tumor (a type of kidney cancer), or are suspected to have it, at the time of first diagnosis, surgery, or radiation treatment. - People whose tumor is found to be Stage I or II may take part in the surgical and biological parts...

**Who might be able to join this trial:** - People aged between 18 and 70 years old (male or female) - People whose general physical functioning is rated at a certain level by their doctor (an ECOG score of 2 or lower, meaning they are able to care for themselves but may not be able to do heavy physical work — confirm...

**Who might be able to join this trial:** - People who are willing and able to give written consent to take part in the trial - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with kidney cancer (renal cell carcinoma) that has spread to other parts of th...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of screening (or 19 or older, depending on local rules) - People whose liver, kidneys, and other organs are functioning well enough, as defined by the trial protocol - People whose cancer can be measured on scans, according to a standard s...

Who might be able to join this trial: - People who have been diagnosed with a hereditary condition called HLRCC and have a confirmed kidney cancer consistent with that diagnosis (Cohort 1), OR people with confirmed non-hereditary papillary kidney cancer (Cohort 2) - People whose kidney cancer has advanced or spread, an...

**Who might be able to join this trial:** - You have been diagnosed with kidney cancer that has been classified as Stage III or Stage IV (meaning it has spread locally or to other parts of the body) - A CT scan with contrast dye has found areas that may be signs of cancer spread (suspected metastases) - You have no kno...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of their transplant - People receiving a kidney transplant, or a combined kidney and pancreas transplant - People who have tested negative for the Epstein-Barr virus (EBV) — a common virus — within the 6 months before transplant up to the...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form, which includes agreeing to a PET/CT scan and, for one group, a tissue biopsy. - People who are able to lie still for 30 to 60 minutes during a PET/CT scan. - People who fall into one...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been recently diagnosed with kidney cancer (renal cell carcinoma), confirmed either by a tissue biopsy or by scans showing the tumor growing over two check-ups (roughly 6–12 months apart) - Your main kidney tumor is larger than 3 cm...

**Who might be able to join this trial:** - People aged 18 years or older - For the Phase Ib part: People who have been diagnosed (by tissue or cell sample) with a locally advanced or metastatic solid tumour (not liver cancer or thyroid cancer) that has progressed after standard treatment, or where standard treatment...

**Who might be able to join this trial:** - People who have signed a consent form and are willing and able to follow the study requirements - People aged 18 years or older - People with a life expectancy of more than 12 weeks - People who have no symptoms from their brain cancer, or only mild symptoms that do not affe...

Who might be able to join this trial: - People who had a CT scan because a kidney tumor was suspected, and the scan showed no signs of kidney cancer - People diagnosed with clear cell renal cell carcinoma (a specific type of kidney cancer) or oncocytoma (a usually non-cancerous kidney growth) who have had their tumor c...

**Who might be able to join this trial:** - People who have been diagnosed (confirmed by laboratory testing) with advanced or metastatic cancer in one of these specific types: liver cancer (hepatocellular carcinoma), kidney cancer (renal cell carcinoma), breast cancer, ovarian or fallopian tube cancer, or endometrial...

**Who might be able to join this trial:** - You are between 18 months and 40 years old at the time of enrollment - You have one of the specific cancer types listed in the trial, such as neuroblastoma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, Wilms tumor, desmoplastic small round cell tumor, or another soft tissu...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of joining the study - People who are able to understand and follow the study requirements, and who have signed a consent form agreeing to take part - People who are relatively well and able to carry out daily activities, as measured by st...

**Who might be able to join this trial:** - People whose age and sex match those of the kidney cancer patient group being studied (the trial site will determine this match) - People who have no tumours in the kidneys, elsewhere in the body, or in the blood system - People who have no benign (non-cancerous) kidney condi...

Who might be able to join this trial: - Adults between 45 and 90 years of age. - People with a kidney tumor that is 7 cm or smaller at its widest point, with more than half of the tumor growing outward from the kidney. Who may not be able to join: - People who have previously had surgery on their kidney. - People whos...

**Who might be able to join this trial:** **For Cohort A or Cohort B (Kidney Cancer groups):** - People with a confirmed diagnosis of advanced kidney cancer (renal cell carcinoma), including any type — clear cell, non-clear cell, or fully sarcomatoid forms - For Cohort A: People who have had any number of previous can...

Who might be able to join this trial: - You must be older than 18 years of age - You have been diagnosed with a type of kidney cancer called renal cell carcinoma (RCC) — either "clear cell" or "non-clear cell" type — confirmed by a tissue or cell sample test - Your cancer has been confirmed to have spread to other part...

Who might be able to join this trial: - People who have given written consent to take part in the study. - People who have been diagnosed with advanced clear cell or papillary renal cell carcinoma (a type of kidney cancer), confirmed by a tissue sample, where no standard treatment is available, suitable, or the person...

Who might be able to join this trial: - You are over 18 years old and have kidney disease or are considered at risk of developing kidney disease - You are already being seen and monitored by a doctor in the Nephrology and Organ Transplantation Department at the University Hospital of Toulouse, France Who may not be ab...

**Who might be able to join this trial:** - Adults aged 18 or older who have given written consent to participate - People who have been diagnosed with kidney cancer (any subtype) confirmed by tissue testing, at a stage where the cancer has grown into nearby large blood vessels (specifically a large vein called the in...

Who might be able to join this trial: - People who have been newly diagnosed with renal cell carcinoma (a type of kidney cancer), including those where the cancer has already spread to other parts of the body at the time of diagnosis - People who were previously diagnosed with kidney cancer that has since spread to oth...

**Who might be able to join this trial:** - You have been diagnosed with kidney cancer (renal cell carcinoma) that contains a specific type of cancer cell called "clear cell" - Your cancer is advanced (cannot be cured with surgery or radiation) or has spread to other parts of the body (stage IV) - You are able to unde...

Who might be able to join this trial: - You have been diagnosed with a kidney tumor (found through an imaging scan such as an MRI or CT) that doctors are considering treating or monitoring closely. - You are 18 years old or older. - You are willing and able to sign a consent form agreeing to take part in the study. Wh...

**Who might be able to join this trial:** - Children and young people aged 18 months to 17 years old - People who have been diagnosed with Wilms tumor (a type of kidney cancer) that has come back or stopped responding to treatment, where the diagnosis was confirmed by a tissue sample at the time of first diagnosis - P...

Who might be able to join this trial: - Adults aged 18 or older (both men and women) who have been diagnosed with a localized kidney tumor that is no larger than 4 cm in size, either before or after surgery. - People who are already scheduled for routine clinical check-ups with the NYU Urology Department as part of the...

**Who might be able to join this trial:** **Group 1 – Healthy Volunteers:** - People aged 2 years or older, male or female - People who are generally in good health based on their medical history **Group 2 – People with Certain Health Conditions:** - People aged 2 years or older, male or female - People who have been...

**Who might be able to join this trial:** - Your cancer must have measurable tumors that can be tracked on scans, following a standard measurement system called RECIST 1.1 (even in areas that were previously treated with radiation, if the tumor has grown there). - You must have one of these cancers that has come back...

**Who might be able to join this trial:** - People aged 18 or older - People who are sufficiently fluent in English - People currently receiving active treatment such as chemotherapy, immunotherapy, hormonal therapy, or radiotherapy - People who have been diagnosed with a genitourinary cancer (such as prostate, kidney,...

Who might be able to join this trial: - You have been diagnosed with kidney cancer (also called renal cell carcinoma, or RCC) - You are currently facing a treatment decision about either an early-stage kidney tumor (T1) or kidney cancer that has spread to other parts of the body - You are willing and able to sign a con...

**Who might be able to join this trial:** - People aged 18 or older - People for whom a robot-assisted partial kidney removal has been recommended due to a suspicious kidney tumour - People whose kidney tumour is considered moderately or highly complex, based on a scoring system called the RENAL Nephrometry Score (a sc...

Who might be able to join this trial: - Adults aged 18 or older - People who had specific scans before surgery, including ultrasound (with and without contrast dye), CT scan with contrast, and MRI - People diagnosed with kidney cancer (renal cell carcinoma) that has spread into nearby blood vessels, confirmed before an...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with high-grade upper tract urothelial cancer (a type of cancer in the lining of the kidney or ureter), confirmed through biopsy, imaging, or urine testing - People who have either refused the main surgery for this cancer (remo...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with kidney cancer (renal cell carcinoma) that is mostly of the "clear cell" type and has either spread to nearby tissues or to other parts of the body - You have at least one tumor that can be measured on a scan, ac...

**Who might be able to join this trial:** - People who have been diagnosed (confirmed by lab testing of cells or tissue) with either clear cell renal cell carcinoma (a type of kidney cancer with clear cell features) for Group 1, or papillary renal cell carcinoma (a type of kidney cancer with papillary features) for Gr...

**Who might be able to join this trial:** - You must be able to understand the study and be willing to sign a consent form agreeing to take part. - You must have confirmed or suspected kidney cancer (either in one location or that has spread), and your doctors must already be planning to remove the tumor or a spread o...

**Who might be able to join this trial:** - People aged 18 years or older - People who have had 2 or more skin cancers (specifically a type called squamous cell carcinoma, confirmed by a skin sample/biopsy) in the past 2 years, OR who have had a medical procedure recorded for the removal or destruction of 15 or more sk...

**Who might be able to join this trial:** - You have been diagnosed with a kidney tumor that is confined to the kidney, measures 7cm or smaller, and appears suspicious for cancer on imaging scans - You have had, or are planning to have, a CT scan (with and without contrast dye) of the tumor within the past year - You a...

**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with kidney cancer (renal cell carcinoma), confirmed through a tissue sample taken during the study's screening process. - People whose kidney cancer is at a certain stage (cT2 to cT4), based on CT or MRI scans taken during scr...

**Who might be able to join this trial:** - You are willing to take part voluntarily and sign a consent form - You are between 18 and 80 years old (male or female) - You have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma, confirmed through a tissue sample test - Your cancer...

**Who might be able to join this trial:** - Adults aged 18 years or older - People with a confirmed diagnosis of non-small cell lung cancer (NSCLC) that has spread or cannot be surgically removed, and where standard approved treatments are no longer an option - People whose cancer has tested positive for a specific ge...

**Who might be able to join this trial:** - People who have been diagnosed with metastatic kidney cancer (specifically the clear cell type), confirmed by a core needle biopsy. - People whose cancer has spread to other parts of the body while the original tumour is still present in the kidney. - People who are willing...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People whose cancer has spread to other parts of the body or cannot be surgically removed - People diagnosed with a specific type of bladder cancer classed as a "variant histology" (such as nested, micropapillary, plasmacytoid, sarcom...

**Who might be able to join this trial:** - People who are able to understand and follow the study requirements - People aged 18 or older at the time of screening - People with a general health and activity level rated as 0 or 1 on a standard oncology scale, meaning they are either fully active or have minor restrictio...

**Who might be able to join this trial:** - People between 18 and 75 years old - People who have been diagnosed with a specific type of kidney cancer (non-clear cell renal cell carcinoma), confirmed by a tissue biopsy — specifically certain subtypes such as papillary RCC (at a certain stage and grade), collecting duct...

Who might be able to join this trial: - People aged 18 or older who have been diagnosed with high-risk upper tract urothelial carcinoma (a type of cancer in the urinary tract), confirmed by laboratory analysis of tissue. - Male participants must agree to use contraception during treatment and for at least 6 months afte...

**Who might be able to join this trial:** - People who have been diagnosed with metastatic prostate, breast, ovarian, or kidney cancer confirmed by tissue testing and imaging scans, and who are starting their first cancer drug treatment - People with metastatic prostate cancer who are starting their first course of do...

Who might be able to join this trial: - People aged 30 or older who are having one of the following robot-assisted keyhole surgeries: removal of the prostate, full removal of a kidney (through the abdomen), or partial removal of a kidney (through the abdomen) Who may not be able to join: - People under 30 years old -...

Who might be able to join this trial: - People who are rated as generally healthy to moderately unwell before surgery, based on a standard health scoring system used by anaesthetists (known as ASA class 1, 2, or 3) - People who are scheduled for a planned (non-emergency) open kidney removal surgery, meaning surgery don...

**Who might be able to join this trial:** - People who have been diagnosed with advanced kidney cancer (specifically the clear-cell type), confirmed by laboratory testing of a tissue or cell sample, who are being considered for continued treatment with nivolumab following an initial course of nivolumab plus ipilimumab...

**Who might be able to join this trial:** - You must be willing to give your consent (or have a legal representative do so) to participate in the study. - You must agree to allow researchers to use stored tumor tissue samples from a previous biopsy (exceptions may be possible if samples are unavailable — confirm with...

**Who might be able to join this trial:** - People who are scheduled to have an uncomplicated robotic-assisted keyhole surgery to remove part of a kidney for a kidney mass at the University of Miami Hospital or one of its network locations (Deerfield Beach, Plantation, Lennar/Coral Gables, or Kendall). - People aged 18...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are willing and able to sign a dated consent form - People who are well enough to carry out daily activities with little or no limitation (based on a standard performance scale rated 0 or 1) - People whose heart, liver, kidneys, and bone...

**Who might be able to join this trial:** - You have been diagnosed with a high-grade cancer of the upper urinary tract (such as the kidney's collecting system or ureter), confirmed by a tissue sample or biopsy, at a stage that has not spread to distant parts of the body. - You are not able to receive cisplatin (a com...

Who might be able to join this trial: - You must be an adult (18 years or older) and able to make your own decision about joining the trial. - You must have been diagnosed with a condition called UTUC (a type of cancer affecting the lining of the upper urinary tract). - You must have received at least one dose of a med...

**Who might be able to join this trial:** - You were 25 years old or younger when diagnosed — though for brain tumors (specifically malignant gliomas) and kidney tumors, there is no upper age limit - You have a suspected or confirmed diagnosis of one of these conditions, at any stage: a brain tumor, a kidney (renal) tu...

**Who might be able to join this trial:** - You are 18 years of age or older - You have a confirmed or suspected diagnosis of a urologic condition (affecting areas such as the bladder, prostate, testicle, ureter, kidney, urethra, penis, or scrotum) and are already scheduled for a surgical biopsy to confirm it - You hav...

Who might be able to join this trial: - People who have recently been diagnosed with kidney cancer (renal cell carcinoma) for the first time - People who have not yet received any treatment for their cancer - People who are willing to have surgery to remove the affected kidney or tumour - People who have signed a writt...

**Who might be able to join this trial:** - People who have advanced kidney cancer (either spread to nearby areas that cannot be surgically removed, or spread to other parts of the body) of any type, whose cancer got worse during or after treatment with a drug called cabozantinib, and who responded to cabozantinib for...

Who might be able to join this trial: - People aged 18 years or older, of any self-identified gender, who meet the other criteria listed. - People who have been diagnosed with a type of kidney cancer called clear cell renal cell carcinoma (RCC), confirmed by a tissue biopsy or sample. - People whose treating urologist...

**Who might be able to join this trial:** - People aged 6 years or older at the time of signing consent forms. Children aged 12 months to under 6 years may also be eligible depending on which part of the trial is currently open (confirm with trial site). - People (or their parents or legal guardians) who are able and...

**Who might be able to join this trial:** - You have been diagnosed with muscle-invasive bladder cancer or cancer of the urethra, ureter, or renal pelvis, confirmed by a tissue biopsy - Your cancer is mainly urothelial (bladder-type) cancer, even if it has some other features mixed in (confirm with trial site for spec...

**Who might be able to join this trial:** - You have a blockage in your ureter (the tube that carries urine from the kidney to the bladder) that is caused by cancer. **Who may not be able to join:** - Your ureteral blockage is caused by something other than cancer (such as a kidney stone or scar tissue). - You have di...

**Who might be able to join this trial:** - People who have signed a written consent form agreeing to take part in the trial. - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (RCC) that includes clear cell features, confirmed by a pathology test. - People who are willing and ab...

**Who might be able to join this trial:** - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (RCC) with clear cell features, confirmed by a tissue sample (biopsy or surgical sample), with or without a more aggressive cell pattern called sarcomatoid features. - People who have had...

**Who might be able to join this trial:** - People who are over 18 years old - People who are able to give written consent to take part in the study - Women who are either past menopause or, if they could become pregnant, using a suitable form of contraception - Men who are using a suitable form of contraception for th...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have an advanced solid tumour that has been confirmed by laboratory testing of tissue or cell samples. - People whose tumour type and treatment history match one of the specific study groups (arms) — for example, tumours...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who are scheduled to have a kidney tumor removed using keyhole (laparoscopic) surgery with robotic assistance - People who have a tumor on one kidney only, or who are having their first surgery for tumors on both kidneys - People who hav...

**Who might be able to join this trial:** - People aged 18 or older - People who speak and read English - People who are scheduled to have their bladder removed (radical cystectomy) or kidney and/or ureter removed (radical nephroureterectomy/ureterectomy), with or without treatment beforehand, and who have enough time...

Who might be able to join this trial: - People who are 18 years old or older - People who have been diagnosed with prostate, kidney, cervical, head and neck cancer, or glioblastoma (a type of brain tumour) - People for whom external radiotherapy (radiation treatment delivered from outside the body) has been recommended...

Who might be able to join this trial: - People who are scheduled to have surgery to remove all or part of a kidney due to a kidney tumour - People who are covered by French social security (the French national health insurance system) - People who have agreed to have their information included in a French kidney cancer...

**Who might be able to join this trial:** - People who have been diagnosed with a specific type of kidney cancer called non-clear cell renal cell carcinoma (the subtypes papillary, chromophobe, oncocytic, unclassified, or "not otherwise specified") that has spread to other parts of the body, confirmed by a tissue or c...

**Who might be able to join this trial:** - You have a known mass (growth) on your kidney where more than 25% of it shows up clearly on imaging scans - The kidney mass measures more than 2 cm but no larger than 7 cm in size - You are older than 18 years of age - You are able to understand the study information and are...

Who might be able to join this trial: - People who have had surgery to remove part or all of a kidney (either a partial or full removal) - People who have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma (ccRCC), confirmed through examination of tissue from the surgery - Peopl...

**Who might be able to join this trial:** - You have been diagnosed with ureteral cancer (cancer in the tube that connects the kidney to the bladder) with certain high-risk features, such as the cancer appearing in multiple spots, being a high-grade (aggressive) type, or having grown into surrounding tissue - You have...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People who have a primary or returning low-grade, non-invasive type of urinary tract cancer (called Upper Tract Urothelial Carcinoma, or UTUC) located in the kidney's collecting system, confirmed by scope examination, biopsy, and urine...

**Who might be able to join this trial:** - People who have recently been diagnosed with multiple myeloma (MM), confirmed using standard international diagnostic guidelines. - People whose general health and ability to carry out daily activities falls within an acceptable range on a standard medical scale (ECOG score...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with kidney cancer - People for whom a doctor has recommended surgery to remove the cancer - People who are able to read and sign a consent form Who may not be able to join: - People who are under 18 years...

**Who might be able to join this trial:** - People who are within 3 years (plus or minus 6 months) of finishing treatment for their first cancer - People whose first cancer treatment included at least one of the following high-risk therapies, as defined by the Canadian Oncology Group: alkylating agent chemotherapy drug...

**Who might be able to join this trial:** - You must be a woman aged 18 or older. - If you are of childbearing age, you must have a negative pregnancy blood test at the start of the study and agree to use an approved form of contraception during the study and for 12 weeks after treatment ends. - If you are postmenopau...

**Who might be able to join this trial:** - People who have been confirmed by tissue testing to have one of the following cancer types that cannot be surgically removed or has spread: high-grade neuroendocrine carcinoma (including small cell or large cell types) of the bladder or urinary tract; squamous cell carcinoma...

**Who might be able to join this trial:** - People who have been diagnosed with VHL disease (Von Hippel-Lindau disease) through genetic testing - People between the ages of 25 and 65 (the trial aims to include an equal spread of ages across this range) - Both males and females are eligible, with the trial aiming for eq...

**Who might be able to join this trial:** **To donate cells (Procurement phase):** - People aged 21 years or older - People who have a solid tumour that tests positive for a protein called GPC3, confirmed by a specific laboratory test showing a sufficient amount of the protein in tumour cells - People whose general he...

**Who might be able to join this trial:** - People who are able to fully understand the study and are willing to sign a written consent form. - People aged 18 years or older and under 80 years old. - People who have a confirmed diagnosis of collecting duct carcinoma (a rare type of kidney cancer) that has spread, come...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer (specifically renal cell carcinoma, or RCC) that has either spread to other parts of the body or cannot be removed with surgery, and where the cancer is mainly of a type called "clear cell" - People who are 18 years of age or...

**Who might be able to join this trial:** - People diagnosed with kidney cancer (renal cell carcinoma) that has spread to other parts of the body or cannot be surgically removed, confirmed by a laboratory test. - People whose cancer got worse, or who could not tolerate, 1 to 2 previous treatments — where at least one...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with a cancer in the upper urinary tract (the lining of the kidney or ureter), confirmed by a tissue sample (biopsy) - Your surgeon has planned for you to have surgery to remove the affected kidney and ureter (called...

Who might be able to join this trial: - Adults aged 18 to 99 years old - People whose overall health makes them a suitable candidate for both a heat/cold-based tumour destruction procedure (ablation) and surgery - People with a tumour that started in the kidney (not one that spread from elsewhere) - People whose kidney...

Who might be able to join this trial: - People aged between 18 and 90 years old. - People who have a kidney tumor that is contained in one area and is suitable for a type of surgery that removes only part of the kidney (called a partial nephrectomy). - People who are able to understand and sign a consent form agreeing...

**Who might be able to join this trial:** - Your child is between 2 months old and 17 years old and has cancer - Your child is likely to develop a fever with a very low white blood cell count (which can happen during cancer treatment) at some point during the study - Parents must be willing to give written permission f...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with metastatic or advanced Collecting Duct Carcinoma or Medullary Renal Cell Carcinoma, confirmed by a specialist pathology review. - People who are willing and able to provide written consent to participate (or have a legal r...

**Who might be able to join this trial:** - People who are able to understand and are willing to sign a written consent form - People who are 18 years of age or older (male or female) - People who have been diagnosed through a tissue biopsy or sample with a specific type of kidney cancer called clear cell renal cell ca...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with advanced kidney cancer (stage IV) confirmed by a tissue sample test - People who have previously received a type of focused radiation treatment (SBRT) together wi...

Who might be able to join this trial: - You are 18 years of age or older (male or female) - A small solid mass (less than 4 cm) was found on your kidney unexpectedly during an imaging scan such as an ultrasound, CT, or MRI - A tissue sample (needle biopsy) has confirmed that the mass is a type of kidney cancer called r...

**Who might be able to join this trial:** - People who are between 18 and 65 years of age - People whose general health before surgery has been assessed as falling within a certain accepted range for anaesthesia risk (known as ASA physical status 1–3 — confirm with trial site what this means for a specific situation) -...

**Who might be able to join this trial:** - You are scheduled for a planned (non-emergency) robotic-assisted surgery on the upper part of the urinary tract at one of the hospitals taking part in this study - You are willing to give your agreement to take part, both verbally and in writing, after being fully informed ab...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer (renal cell carcinoma) that has spread to other parts of the body, confirmed by a tissue sample, and the cancer includes a specific type called "clear-cell." - People whose kidney cancer is classified as "intermediate-risk" o...

Who might be able to join this trial: - You must be 18 years of age or older - You have been diagnosed with kidney cancer (renal cell carcinoma) confirmed by a biopsy - There is no sign of the cancer having spread to other parts of the body, based on physical examination or scans - You are not suitable for surgery or o...

**Who might be able to join this trial:** **For patients:** - Adults aged 18 or older - People scheduled to have a type of keyhole surgery (laparoscopic robotic-assisted partial nephrectomy) as the first treatment for a tumour on one or both kidneys - People who have agreed to have their information added to a medical...

**Who might be able to join this trial:** - People who have given written consent to take part (or whose legal representative has done so on their behalf) - People who agree to allow stored tumor tissue from a previous biopsy to be used for the study (exceptions may be possible with approval from the lead researcher)...

**Who might be able to join this trial:** - People who have been diagnosed with monoclonal immunoglobulin deposition disease (a condition where abnormal proteins build up in the body's organs) and have not yet received treatment targeting the abnormal plasma cells causing it. - People who are reasonably active and abl...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of screening - People who have given written consent to participate before any study-related procedures begin - People with a life expectancy of at least 12 months - People diagnosed with renal cell carcinoma (a type of kidney cancer) conf...

Who might be able to join this trial: - People who have been diagnosed with locally advanced or metastatic renal medullary carcinoma (RMC) or epithelioid sarcoma (ES), confirmed by specialist pathology review, or a rare related kidney cancer variant that is SMARCB1-negative but occurs in people without sickle cell dise...

**Who might be able to join this trial:** - You must be 18 years of age or older - You must have been diagnosed with a specific type of kidney cancer called "clear cell renal cell carcinoma," confirmed by a lab analysis of removed tissue - You must have had surgery to remove your kidney (fully or partially) and/or any...

Who might be able to join this trial: - You have kidney cancer that has spread to other parts of the body, with no more than 5 spread sites and no more than 3 different organs affected. - You are between 20 and 80 years old. - Each area where the cancer has spread is no larger than 5 cm (about 2 inches) at its widest p...

Who might be able to join this trial: - Adults between 18 and 65 years of age - People who are having surgery to remove one kidney - People whose overall health before surgery is classified by their medical team as ASA II or III (meaning they have either a mild or moderate ongoing health condition — confirm with trial...

**Who might be able to join this trial:** - People who have given their written agreement to participate in the trial - People aged 18 or older - People who have been diagnosed with, or are suspected to have, a type of kidney cancer called clear cell renal cell carcinoma - People whose life expectancy is at least 6 mon...

**Who might be able to join this trial:** - You are 18 years of age or older - You are scheduled to have surgery to remove all or part of your kidney due to a kidney tumor, at Bordeaux University Hospital's urology department - You have had, or are scheduled to have, a CT scan (a type of detailed X-ray) as part of your...

Who might be able to join this trial: - People aged 18 or older - People who have been diagnosed with kidney cancer that has not spread beyond the kidney - People whose treatment plan has been reviewed and approved at a multidisciplinary medical team meeting - People who are scheduled to have a partial or full keyhole...

**Who might be able to join this trial:** - People aged 18 years or older - People with a kidney mass that has not spread to nearby lymph nodes or other parts of the body, and is at an early stage (clinical stage T1 or T2) - People who are planned to have a type of keyhole kidney surgery assisted by a robotic system (c...

Who might be able to join this trial: - You must be 18 years old or older. - You must have been diagnosed with a specific type of kidney cancer called "predominantly clear cell carcinoma," confirmed by a tissue test. - A sample of your tumor tissue (from the original tumor or a site where cancer has spread) must be ava...

**Who might be able to join this trial:** - People aged 18 to 80 years old, of any gender - People diagnosed with advanced clear cell renal cell carcinoma (a type of kidney cancer) or tumors linked to a condition called von Hippel-Lindau (VHL) Syndrome - People who are generally well enough to carry out light activity...

Who might be able to join this trial: - People who need to have a kidney completely removed (called a radical nephrectomy) for any medical reason Who may not be able to join: - People whose health condition means they cannot safely undergo keyhole (laparoscopic) surgery for any reason - People whose blood pressure or...

**Who might be able to join this trial:** - You have had scans or imaging that suggest there may be a growth or mass on one of your kidneys - Both men and women can take part - You are 18 years of age or older - Your condition has been assessed as suitable for a type of surgery called a partial nephrectomy (where only...

**Who might be able to join this trial:** - People (male or female) who have been diagnosed with breast cancer and have received treatment such as chemotherapy, radiotherapy, surgery, or other breast cancer treatments. - People with a cancer other than breast cancer who received chemotherapy containing anthracyclines...

**Who might be able to join this trial:** - You have been diagnosed with an advanced, inoperable, or spreading solid tumor (such as ovarian, pancreatic, bladder, kidney, liver, gastrointestinal, lung, prostate, or breast cancer) confirmed by a lab test, OR you have been diagnosed with multiple myeloma. - Your cancer h...

Who might be able to join this trial: - People who have read, understood, and signed a consent form agreeing to take part in the study voluntarily - People aged 18 or older but under 70, of any gender - People who have been confirmed by laboratory testing to have advanced kidney cancer (renal cell carcinoma) that tests...

**Who might be able to join this trial:** - Adults aged 18 or older who are scheduled to have surgery to fully or partially remove a kidney because of kidney cancer. - People who are considered to be in reasonably good to moderate overall health before surgery, based on a standard medical assessment (known as ASA class...

**Who might be able to join this trial:** - People who have had surgery to remove a kidney and ureter (called radical nephroureterectomy) and whose lab results confirmed cancer of the renal pelvis or ureter, at an advanced stage (classified as pT3-4 or pN+ under standard staging guidelines) - People whose kidneys are...

**Who might be able to join this trial:** - You have been diagnosed with clear cell kidney cancer (a specific type of kidney cancer) that has spread to other parts of the body - Your cancer is progressing in only a small number of spots (5 or fewer areas) - All of the spots where your cancer is progressing can be safel...

**Who might be able to join this trial:** - People aged 6 months to 25 years old - People with a solid tumour that has come back or stopped responding to treatment, and who were unable to have, or did not benefit enough from, a stem cell transplant using their own cells — this includes specific cancers such as high-ri...

**Who might be able to join this trial:** - People who are willing to take part and sign a written consent form - People aged 18 or older - People whose general health and ability to carry out daily activities meets a certain minimum level, as measured by a standard medical scale (confirm with trial site) - People who...

**Who might be able to join this trial:** - People diagnosed with cancer of the renal pelvis (part of the kidney) or ureter (the tube connecting the kidney to the bladder), confirmed through symptoms, scans, tissue samples, urine tests, or a specialised genetic test called FISH - People where specialist doctors (an im...

**Who might be able to join this trial:** - You have been diagnosed with metastatic urothelial cancer (a type of cancer affecting the urinary tract lining) that has been confirmed by a tissue sample (biopsy) from either the original tumour or one of the areas it has spread to. - Your cancer has spread to no more than...

**Who might be able to join this trial:** - People who have been diagnosed with a specific type of kidney cancer (called clear cell renal cell carcinoma, with or without certain aggressive features) that has been confirmed by laboratory testing of removed tissue. - People who have had surgery to remove all or part of...

**Who might be able to join this trial:** - People aged 18 to 80 at the time of signing the consent form, of any gender, who are well enough to carry out daily activities with little or no limitation (as measured by a standard performance score of 0 or 1) - People who have been diagnosed with kidney cancer that contai...

Who might be able to join this trial: - People between 18 and 80 years old, of any sex - People who have been diagnosed with kidney cancer (particularly certain types called clear cell renal cell carcinoma or papillary renal cell carcinoma) confirmed by a tissue sample, or who have a suspected kidney cancer identified...

**Who might be able to join this trial:** - You are willing to take part voluntarily, are able to follow the study requirements, and agree to sign a consent form - You are 18 years of age or older - You have been diagnosed with kidney cancer (renal cell carcinoma) that has come back or spread, and this was confirmed t...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of signing the consent form. - People who are able to give their own informed consent, or who have a legally authorised representative who can do so on their behalf. - People who have signed and dated the consent form approved by the ethic...

**Who might be able to join this trial:** - People who are willing and able to sign a written consent form agreeing to take part in the study - People who are 18 years of age or older - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (RCC) that includes a "clear cell" component...

Here is the eligibility information in plain English: **Who might be able to join this trial:** - You have a kidney tumor that doctors have determined can be treated with surgery - You have had a full contrast-enhanced CT scan (a detailed scan using a dye to highlight blood vessels and organs) within the 30 days befor...

Who might be able to join this trial: - People who have a single, newly diagnosed kidney tumour on one side only, that is suspected to be kidney cancer (not inherited or familial) - People who are scheduled to have robot-assisted keyhole surgery to remove the tumour while keeping the rest of the kidney - People whose o...

Who might be able to join this trial: - You have prostate cancer that has spread and is no longer responding to hormone therapy (confirm with trial site), and you are starting a specific type of targeted radiation treatment called 177Lu-PSMA therapy for the first time at the Klinikum rechts der Isar hospital. Who may...

**Who might be able to join this trial:** - Adults aged 18 or older. - People who are scheduled to have a partial kidney removal surgery for a kidney mass that is 7 cm or smaller. - People who have no more than one active cancer at the time of joining (people with a past or separate cancer may still be considered if th...

**Who might be able to join this trial:** - People who have been formally diagnosed with kidney cancer (renal cell carcinoma) of any subtype, confirmed through laboratory testing of tissue - People who are 18 years of age or older - People whose general physical health and ability to carry out daily activities falls w...

**Who might be able to join this trial:** - You have been diagnosed with clear cell kidney cancer, confirmed by a lab test of tissue or cells. - You have already tried and not responded to no more than 2 targeted therapy drugs (not including a type called mTOR inhibitors) and 1 immunotherapy drug. - It has been at lea...

**Who might be able to join this trial:** **For adults with intellectual disability (ID):** - You are 18 years or older and have already been diagnosed with an intellectual disability, confirmed by specific test scores - A doctor has cleared you to take part in moderate-to-vigorous physical activity, based on standard...

Who might be able to join this trial: - You are 65 years old or older - You have an early-stage kidney tumor (stage T1) and are scheduled to have surgery to remove either part or all of the affected kidney - You have been assessed as being somewhere between "managing well" and "moderately frail" on a standard frailty s...

**Who might be able to join this trial:** - You have been diagnosed with an early-stage (stage cT1) kidney tumor that has been confirmed by a CT scan or MRI before surgery - You are scheduled to have a surgery called a partial nephrectomy (where only part of the kidney is removed, not the whole kidney) - Your kidney tu...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People with a laboratory-confirmed diagnosis of urothelial carcinoma (a type of cancer affecting the bladder or upper urinary tract) that has spread to nearby lymph nodes and/or to other parts of the body, wit...

**Who might be able to join this trial:** - You (or your legal guardian/caregiver) must be willing and able to sign a consent form agreeing to take part. - You must be between 18 and 75 years old. - You must have a suspected kidney cancer diagnosis based on standard imaging scans, and be scheduled to have a special typ...

**Who might be able to join this trial:** - People who have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma (ccRCC), confirmed by a tissue biopsy. A type of aggressive cancer cell pattern called sarcomatoid features is also allowed. - People who are 18 years of age or older....

Who might be able to join this trial: - Adults aged 18 or older at the time of giving consent. - People who have signed a written consent form and agreed to the release of personal health information before joining the trial. - People who are generally well enough to carry out light activity and care for themselves, as...

**Who might be able to join this trial:** - You are 18 years old or older - You need a ureteric stent (a small tube placed in the urinary tract) because of kidney stones or because a cancer in the abdomen or pelvis is pressing on the tubes that connect your kidneys to your bladder - You have had a ureteric stent before...

**Who might be able to join this trial:** - You are joining the study by choice, have signed a consent form, and are willing and able to follow the study plan - You are 18 years old or older - You are able to carry out your daily activities, either fully or with only minor limitations (this is measured by a standard sc...

**Who might be able to join this trial:** - People who choose to take part voluntarily - People aged between 18 and 80 years old - People with a good general level of physical functioning (able to carry out normal daily activities with at most minor limitations, as rated by a doctor) - People who have been diagnosed t...

**Who might be able to join this trial:** - You are 18 years old or older - You have received a kidney transplant (up to your third kidney transplant) - Your transplant took place between 12 and 48 months ago - Your transplanted kidney is working at a stable level, meaning your kidney function and protein levels in uri...

**Who might be able to join this trial:** - People aged 18 or older at the time of giving consent to participate - People who are able to give their own consent, or who have a legally authorised representative who can consent on their behalf - People who have signed and dated the official consent form approved by the...

Who might be able to join this trial: - People between 18 and 80 years old, of any sex - People who have been diagnosed with kidney cancer (particularly a type called clear cell renal cell carcinoma), lymphoma, or nasopharyngeal carcinoma (a type of cancer affecting the back of the nose and throat), either confirmed by...

Who might be able to join this trial: - People aged 18 or older at the time of giving consent. - People with advanced or metastatic kidney cancer (renal cell carcinoma) that includes a specific type called "clear cell." - People who have previously been treated with a type of immunotherapy called an anti-PD-1 drug, and...

Who might be able to join this trial: - You must be 18 years old or older - You must have been diagnosed with a specific type of kidney cancer called "clear cell renal cell carcinoma," confirmed by a tissue or cell sample test - Your cancer must have spread to other parts of the body, as shown by a scan or biopsy of th...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form. - People whose treating doctor considers them a suitable candidate for treatment with ipilimumab and nivolumab for kidney cancer that has spread to other parts of the body. - People who are reasonabl...

**Who might be able to join this trial:** - You have been diagnosed with a kidney tumor and are scheduled to have a robot-assisted surgery that removes only part of the kidney (not the whole kidney) - Your kidney tumor measures 7 centimeters (about 2.75 inches) or smaller - You are between 19 and 80 years old - You are...

Who might be able to join this trial: - You have a growth or mass on your kidney that is up to 4 cm in size - You are an adult aged 18 or older - Your doctors have said you are a suitable candidate for kidney surgery - You have read, understood, and signed a consent form agreeing to take part Who may not be able to jo...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with kidney cancer that has spread to other parts of your body at the same time as the original diagnosis (called synchronous metastatic kidney cancer) - Your original kidney tumor has not been surgically removed yet - You h...

**Who might be able to join this trial:** - People aged 18 or older, of any sex, who are willing and able to sign a consent form. - People who are expected to live for more than 8 weeks. - People with a good general level of functioning — specifically, a performance status score of 0 or 1 on the ECOG scale, meaning th...

**Who might be able to join this trial:** - People aged 18 or older - People with a life expectancy of more than 3 months - People who have been diagnosed with colorectal cancer (Stage I or II) confirmed by a tissue sample analysis - People whose cancer is classified as T1–T3, N0, M0 (meaning the tumour is limited in...

**Who might be able to join this trial:** - You have been diagnosed with kidney cancer (renal cell carcinoma) that has come back and spread to other parts of the body, confirmed by a PET/CT scan or similar full-body imaging. - You have 5 or fewer areas where the cancer has spread that can all be fully targeted with rad...

Who might be able to join this trial: - Adults who are 18 years of age or older - People who were admitted to an intensive care unit (ICU) at some point between January 1, 2013, and December 31, 2023 - People who have been diagnosed with a blood cancer (such as leukemia or lymphoma) or a solid tumor that required chemo...

**Who might be able to join this trial:** - You are willing and able to read and sign a consent form before any study procedures begin. - You are 18 years of age or older. - Your kidney cancer has been confirmed by a tissue or cell sample and is mainly the "clear cell" type. - You have a primary (original) kidney tumo...

**Who might be able to join this trial:** - Imaging (such as a scan) has confirmed a stage T1 kidney tumor (either T1a or T1b), and the treating doctor believes a surgery to remove part of the kidney would be beneficial. - People aged between 18 and 90 years. - People with no history of serious kidney disease or condi...

**Who might be able to join this trial:** - People who are able to understand and voluntarily sign a consent form, and are willing and able to follow the trial procedures - People aged between 18 and 75 years (any gender) - People who have been diagnosed with, or are suspected to have, kidney cancer (renal cell carcin...

**Who might be able to join this trial:** - You are 70 years old or older - You have been diagnosed with advanced or spreading (metastatic) kidney cancer that has been confirmed - You have not yet received any treatment for your cancer after it spread (metastatic stage) - Your general health and ability to carry out da...

**Who might be able to join this trial:** - People who have been diagnosed with advanced or metastatic clear cell kidney cancer (confirmed by a tissue or cell sample) and have already received at least one prior treatment for their advanced disease, including a type of immunotherapy called a PD-1/PD-L1 checkpoint inhi...

**Who might be able to join this trial:** - Adults aged 18 or older. - People with an advanced solid tumour cancer that fits into one of the following groups: any solid tumour with at least 3 metastatic lesions (areas where cancer has spread) visible on standard scans; a high-grade brain tumour (WHO grade 3 or 4 gliom...

Who might be able to join this trial: - Adults aged 18 or older who are scheduled to have a ureteroscopy procedure (a procedure where a thin camera is used to look inside the urinary tract) to investigate or treat a known or suspected tumor in the upper urinary tract - People who are able to give their informed consent...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a complex kidney cyst (classified as Bosniak category II or higher) - People who are already scheduled to have surgery to remove a kidney mass (either partial or full removal of the kidney, using open, keyhole, or robotic surgery) -...

**Who might be able to join this trial:** - People who are willing to take part and are able to sign a consent form themselves, or have a legal representative who can sign on their behalf. - Adults between 18 and 75 years of age, of any gender. - People who have a suspected or confirmed primary kidney cancer diagnosis...

**Who might be able to join this trial:** - You are willing to take part and have signed a consent form agreeing to participate - You are between 18 and 75 years old (male or female) - Your doctors expect you to live for at least 3 more months - You are generally active and able to care for yourself, with little or no...

Who might be able to join this trial: - The person must be willing to give verbal consent to take part in the study. - The person must be willing and able to follow the study procedures, as judged by the study team. - The person must be 18 years of age or older at the time of giving consent. - For patients: The person...

**Who might be able to join this trial:** - You have been diagnosed with advanced or metastatic kidney cancer (renal cell carcinoma), bladder/urinary tract cancer (urothelial cancer), or prostate cancer that no longer responds to hormone-reducing treatment (castration-resistant prostate cancer) - You are able to swallo...

**Who might be able to join this trial:** - People who have been diagnosed with urothelial carcinoma (a type of cancer affecting the lining of the kidney's collecting system, ureter, bladder, or urethra) confirmed by laboratory analysis of tissue or cells, where the cancer cannot be fully removed by surgery or has com...

**Who might be able to join this trial:** - You have been diagnosed with kidney cancer (renal cell carcinoma), either confirmed by a tissue sample or by a specialist medical team's assessment - Your cancer cannot be treated with surgery, removal of spread tumours, or ablation (burning/freezing) due to factors related t...

**Who might be able to join this trial:** - You must be 18 years of age or older - You have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma, confirmed through a tissue sample test - Your cancer has spread to other parts of the body (advanced or metastatic stage) - You are abo...

**Who might be able to join this trial:** - You have signed (or are willing to sign) a consent form agreeing to take part in the study - You have been diagnosed with a solid tumor (a type of cancer) and your treatment plan includes a platinum-based chemotherapy drug (either cisplatin or carboplatin) - Your doctor expec...

**Who might be able to join this trial:** - People aged 18 to 80 years, of any gender - People who have given written consent to participate, either personally or through a legally authorised representative, after being fully informed about the trial - People whose pre-surgery scans (CT or MRI) have confirmed a small...

**Who might be able to join this trial:** - You have been diagnosed with a type of kidney cancer called metastatic clear cell renal cell carcinoma, and it was first found less than 12 months ago - You are 18 years of age or older - Your cancer is considered lower risk based on a scoring system called the IMDC score (s...

Who might be able to join this trial: - Adults aged 18 or older at the time they entered the study - People diagnosed with a type of kidney cancer called papillary renal cell carcinoma (PRCC) that cannot be surgically removed and has either spread locally or to other parts of the body, or people diagnosed with kidney c...

**Who might be able to join this trial:** - People who are older than 18 years of age - People who have been diagnosed with advanced or spreading kidney cancer (called Renal Cell Carcinoma) that includes a specific type known as "clear-cell" - People who have not yet received any systemic (whole-body) treatment for the...

**Who might be able to join this trial:** - You have signed a written consent form agreeing to take part in the study - You have been diagnosed with heart failure with reduced pumping function (HFrEF) for at least three months before your screening visit - You have had a heart ultrasound (echocardiogram) within the la...

**Who might be able to join this trial:** - People diagnosed with non-muscle-invasive bladder cancer (a form of bladder cancer that has not grown deep into the bladder wall) who have already had an initial surgical procedure to remove a bladder tumor and are scheduled for a second surgical procedure, for one of these...

**Who might be able to join this trial:** - You are willing and able to give your informed consent to take part in the trial - Your kidney cancer has been confirmed by a tissue sample (biopsy) and is a specific type called clear-cell or sarcomatoid renal cell carcinoma - Your cancer is at a certain stage or spread, as...

**Who might be able to join this trial:** - You are an adult (18 or older) who has been diagnosed with kidney cancer or is suspected of having kidney cancer - You have been referred to Yale Genitourinary Oncology providers in the Urology, Medical Oncology, Radiation Oncology, or Nephrology departments at Yale - You are...

**Who might be able to join this trial:** - People who have been confirmed by tissue testing to have a type of kidney cancer (renal cell carcinoma with clear cell component) that cannot be removed by surgery and has either spread locally or to other parts of the body - People who have not had any previous systemic (wh...

Who might be able to join this trial: - People aged 16 to 85 years who have end-stage kidney disease and are being considered for a kidney transplant, including those already on dialysis or approaching the need for it. - People whose overall health has been assessed by doctors as suitable for transplant surgery and for...

**Who might be able to join this trial:** - People of any sex who are 18 years of age or older - People willing to sign a consent form and follow all study requirements - People who have been confirmed through a tissue sample (biopsy) to have a type of kidney cancer called renal cell carcinoma (RCC) with a "clear cell...

**Who might be able to join this trial:** - People aged 18 or older, of any gender, who agree to take part voluntarily and sign a consent form — and whose family members living with them also agree and sign consent - People who have been diagnosed with a kidney tumour and have already had surgery to remove all or part...

Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the trial - People who are 18 years of age or older - People who have been diagnosed with glioblastoma (a type of brain tumour) or clear cell renal cell carcinoma (a type of kidney cancer) Who may not be able to join...

Who might be able to join this trial: - People who have been diagnosed with a type of kidney cancer called clear cell renal cell carcinoma (ccRCC) that has spread or cannot be surgically removed, and for which standard treatments no longer exist or are no longer working. - People whose tumor tissue test shows that at l...

Who might be able to join this trial: - You are willing and able to give your consent to take part in the trial - You are 18 years old or older - You have been diagnosed with advanced kidney cancer (renal cell carcinoma), confirmed by a laboratory test on a tissue sample - You have been taking a stable dose of a cancer...

Who might be able to join this trial: - You have been diagnosed with a type of cancer in the lining of the upper urinary tract (the kidneys or ureters), confirmed by a tissue sample test - You are 18 years of age or older - You are willing and able to give your formal agreement to take part in the trial Who may not be...

**Who might be able to join this trial:** - Adults aged 18 or older of any gender - People with advanced clear cell kidney cancer (a specific type of kidney cancer) confirmed by laboratory testing, where curative surgery is not possible - People who have not yet received any systemic (whole-body) treatment for their a...

**Who might be able to join this trial:** - You must be 18 years of age or older - For Groups A and B: You have been diagnosed with bladder cancer or upper urinary tract cancer (confirmed by a tissue biopsy), and your cancer has gotten worse despite treatment with the drugs enfortumab vedotin and pembrolizumab (these...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with cancer of any type or stage - People who finished surgery, chemotherapy, immunotherapy, radiotherapy, or an experimental treatment at least one month before the study begins (people on stable doses of hormone ther...

Who might be able to join this trial: - You must be able to understand and be willing to sign a consent form approved by an ethics review board - You must be 18 years old or older at the time you sign the consent form - You must be scheduled to have a robotic surgery to remove all or part of a kidney Who may not be ab...

**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed (confirmed by laboratory tissue testing) with a type of kidney cancer called clear cell renal cell carcinoma that cannot be removed by surgery, has spread locally, or has spread to other parts of the body - Your kidney c...

Who might be able to join this trial: - Adults aged 18 or older - People who had a confirmed diagnosis of kidney cancer (renal cell carcinoma) before and during surgery - People who have undergone surgery to remove all or part of the affected kidney Who may not be able to join: - People whose medical records have sign...

Who might be able to join this trial: - Adults aged 18 years or older - People who have a confirmed diagnosis of HIV or AIDS - People who have signed the trial consent form Who may not be able to join: - People who identify as Indigenous, or people who are currently in prison (in any type of prison arrangement) - Peop...

Who might be able to join this trial: - People who were treated for kidney cancer at Wuhan Union Hospital between August 2025 and August 2026 - People who are older than 18 years of age - People who had at least one CT scan of the abdomen before starting treatment - People whose kidney cancer diagnosis was confirmed th...

**Who might be able to join this trial:** - People who have been diagnosed with kidney cancer (specifically, unresectable advanced or metastatic renal cell carcinoma with a clear cell component, or a type called translocation renal cell carcinoma) that cannot be removed by surgery, confirmed by laboratory testing of a...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with cancer of the ureter, confirmed by a scope procedure (ureteroscopy) and imaging scans (such as CT, MRI, or PET-CT), with no signs that the cancer has spread to other parts of the body - People whose biopsy r...

**Who might be able to join this trial:** - People who have given written consent to take part (or whose legal representative has done so on their behalf) - People who agree to allow stored tumor tissue from a previous biopsy to be used for the study (exceptions may be possible with approval from the study's lead doct...

Who might be able to join this trial: - People aged between 18 and 80 years old, of any gender - People whose scans show a kidney tumor measuring 7 cm or smaller - People whose imaging shows the tumor has not spread into the kidney's internal drainage system - People who are already scheduled to have a robot-assisted p...

**Who might be able to join this trial:** - You have been diagnosed with kidney cancer (renal cell carcinoma), confirmed by a laboratory examination of tissue removed during surgery. - You had a specific type of detailed CT scan (with very thin image slices of 1mm or less) done at the trial institution before your surg...

**Who might be able to join this trial:** - People aged 14 years or older - People who have been diagnosed with von Hippel-Lindau (VHL) syndrome, either through clinical assessment or genetic testing - People who have VHL-related tumours that can be measured or that have been growing, as shown by specific imaging scan...

**Who might be able to join this trial:** **For receiving an invitation to the study:** - You have been identified as a current or former smoker and are registered as living in the West Yorkshire and Harrogate or Humber and North Yorkshire area, making you eligible for a local lung cancer screening programme. - You ar...

Who might be able to join this trial: - People who are willing and able to give written consent to participate - People aged 18 or older - People who have been confirmed, through tissue testing and imaging scans, to have kidney cancer (renal cell carcinoma) that falls into one of these categories: a larger tumour with...

Who might be able to join this trial: - People diagnosed with one of the following cancers that has come back or stopped responding to treatment: rhabdomyosarcoma, Ewing sarcoma, neuroblastoma, or Wilms tumor - People whose cancer has not responded to, has returned after, or still shows signs of disease following stand...

**Who might be able to join this trial:** **Initial eligibility (pre-screening):** - People aged 18 or older at the time of signing the consent form - People diagnosed with kidney cancer (renal cell carcinoma) that has spread to other parts of the body or cannot be removed by surgery or treated with radiation - People...

**Who might be able to join this trial:** - People who have been diagnosed with advanced clear cell kidney cancer (confirmed through a tissue sample test) - People whose kidney cancer has continued to grow or spread on imaging scans after being treated with a type of immunotherapy called a checkpoint inhibitor — eithe...

**Who might be able to join this trial:** - People who have been diagnosed with clear cell renal cell carcinoma (a specific type of kidney cancer) confirmed by a biopsy. - People whose kidney cancer has been classified as intermediate-high risk, high risk, or stage M1 (spread to one isolated area that can be fully rem...

**Who might be able to join this trial:** - You must be at least 18 years old at the time you give your consent to participate. - You must be well enough to carry out most daily activities (your doctor will assess this using a standard health scale within 2 weeks before signing up). - Your kidney cancer must have been...

**Who might be able to join this trial:** - You have a growth (mass) on your kidney that has been confirmed by a CT scan or MRI. - Your doctors have recommended a surgery called a partial nephrectomy (surgery to remove part of the kidney, not the whole organ). - You are willing and able to sign a consent form agreeing...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of locally advanced or metastatic clear cell renal cell carcinoma (a specific type of kidney cancer), confirmed by laboratory tissue analysis. - For part 1 of the trial: People who have already received at least two different treatment pl...

Who might be able to join this trial: - People who have advanced or metastatic clear cell kidney cancer or non-small cell lung cancer that has gotten worse within 6 months of stopping a type of immunotherapy called PD-1/PD-L1 therapy (this immunotherapy does not need to have been the most recent treatment received). -...

**Who might be able to join this trial:** - People aged 18 or older. - People who have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma (ccRCC), confirmed by a tissue or cell sample (biopsy). - People who have between 1 and 5 measurable areas where cancer has spread (metastas...

Who might be able to join this trial: - Adults aged 18 or older - People who have had a diagnostic ultrasound performed at the University of North Carolina - People who are already scheduled to have a biopsy - People whose lesion (an area of concern) was visible on an ultrasound scan - People who are able to give their...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are scheduled to have a procedure called ureteroscopic laser ablation to treat a tumour in the renal pelvis (the part of the kidney where urine collects) - People whose tumour is in the renal pelvis, has been confirmed as a type of cancer...

Who might be able to join this trial: - You are 18 years old or older - You have a single kidney tumor on one side only, measuring 7 cm or smaller, confirmed by a CT scan (this is called early-stage kidney cancer, or stage cT1) - There is no sign that the cancer has spread to other parts of the body or nearby lymph nod...

Who might be able to join this trial: - People who have been diagnosed with a type of kidney cancer called Renal Cell Carcinoma (RCC), either as an individual or together with their partner or spouse - Partners or spouses of kidney cancer patients who meet the criteria for this trial - Patients who have had surgery to...

**Who might be able to join this trial:** - People aged 18 to 75 years old (including those who are exactly 18 or 75) - People who are willing to take part and sign a consent form agreeing to join the study - People with a good general health and activity level, able to carry out normal daily activities with little or...

**Who might be able to join this trial:** - You are 18 years old or older and have been diagnosed with kidney cancer that has spread to other parts of the body (metastatic renal cell carcinoma) - You are currently receiving a type of cancer treatment called immunotherapy (immune checkpoint inhibitor therapy), and your...

**Who might be able to join this trial:** - People aged 3 years or older - People who are about to receive a kidney transplant, or who received one within the past 2 weeks before the screening date - People whose transplant surgeon has decided they should receive preventive antiviral medication against CMV and/or EBV -...

Who might be able to join this trial: - People who have fully understood and voluntarily signed the consent form for the study - People who are over 18 years old at the time of signing the consent form (any gender) - People whose kidneys are functioning at a certain level before surgery, measured by a blood test called...

Who might be able to join this trial: - The tumour tissue sample must test positive for a protein called GPNMB at high levels, confirmed by a central laboratory using a specific staining test. - People must have a confirmed diagnosis of one of these cancer types that is advanced, has spread, come back, or cannot be su...

Who might be able to join this trial: - You must be 18 years of age or older - You must be well enough to carry out some daily activities (not completely disabled by illness) (confirm with trial site) - Your kidney cancer must have been confirmed by a tissue sample (biopsy or similar test) - Your tumor must be in one s...

**Who might be able to join this trial:** - People diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma (ccRCC) that has spread or cannot be surgically removed. - People whose cancer has continued to grow after receiving standard treatments, or who have declined standard treatments. -...

**Who might be able to join this trial:** *For people with cancer (tumor subjects):* - A person or their legal representative is able to read, sign, and date a consent form - The person agrees to follow the study procedures for the entire duration of the trial - Adults aged 18 or older, of any gender - People who have...

Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the study. - People aged 18 or older. - People who are being considered for surgery to fully remove a kidney, with or without removal of nearby lymph nodes. - People diagnosed with high-risk kidney cancer meeting at l...

Who might be able to join this trial: - You are between 18 and 80 years old - You are planning to have a robot-assisted surgery to remove part of your kidney Who may not be able to join: - Your anesthesiologist (the doctor who manages your sleep during surgery) has determined that general anesthesia is not safe for yo...

Who might be able to join this trial: - People who are 21 years of age or older - People who have been diagnosed with at least one long-term (chronic) health condition, as recorded in their medical records - People who live independently in the community (rather than in a care facility or hospital) - People who speak a...

Who might be able to join this trial: - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (with a clear cell component) that has spread or cannot be removed or cured with surgery or radiation - People who have areas of cancer that can be measured or assessed on scans, including tho...

**Who might be able to join this trial:** - People who are willing and able to give written consent to participate. - People aged between 18 and 85 years old, of any gender. - People with a physical fitness/activity level rated as 0 or 1 on a standard oncology scale (meaning fully active or able to carry out light wor...

**Who might be able to join this trial:** - People who are willing and able to give written consent to participate. - People aged 18 to 79 years old, of any gender. - People with a general physical fitness rating of 0 or 1 on a standard oncology scale (meaning fully active or able to carry out light activity). - Peopl...

Who might be able to join this trial: - You are 16 years of age or older - You have been admitted to a participating urology department at a hospital - You have been admitted as an emergency where blood in the urine (haematuria) is one of the main reasons for your visit, and you are being cared for by a urology team W...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with a specific type of kidney cancer called clear cell renal cell carcinoma (ccRCC), confirmed through a tissue sample taken with a needle. People who have not yet had a biopsy may be considered for screening if kidne...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form - People aged 18 or older, of any gender - People who have a confirmed diagnosis of clear cell renal cell carcinoma (a specific type of kidney cancer) - People whose kidney cancer has...

Who might be able to join this trial: - You have been diagnosed with kidney cancer (either confirmed by a tissue sample, or strongly suspected based on medical scans) - Your cancer has not spread to other parts of the body - You are 18 years old or older - Your doctor believes you are able to understand what the study...

**Who might be able to join this trial:** - People who have been assessed as low-to-moderate risk for surgery, based on a standard pre-surgery health scoring system (scores 1 to 3 out of 5 on the ASA scale) - People who need a full removal of a non-functioning kidney, or removal of half a kidney, due to a long-term be...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with advanced or metastatic kidney cancer (specifically a type called clear cell renal cell carcinoma) that cannot be cured with surgery or radiation, at any risk level - People whose cancer can be measured on scans ac...

**Who might be able to join this trial:** - You are 18 years old or older - Your kidney cancer has been confirmed by a tissue sample (biopsy) as a specific type called "clear cell renal cell carcinoma" - Your cancer has come back after previous treatment or has spread to other parts of the body - You are already receiv...

Who might be able to join this trial: - You must be at least 18 years old at the time of signing the consent form. - You must have a type of kidney cancer called clear cell renal cell carcinoma (or a related type that includes clear cell features) that cannot be surgically removed or has spread, and has gotten worse de...

**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with advanced or metastatic kidney cancer (with a specific cell type called "clear cell") that has been confirmed through a tissue or cell sample, and who have already received at least one immunotherapy drug (a PD-1/PD-L1 chec...

**Who might be able to join this trial:** - You must be willing and able to give written consent before starting any treatment; if you have a history of serious psychiatric illness, your family must also give their consent - You must be between 18 and 80 years old at the time of signing the consent form - You must be...

**Who might be able to join this trial:** - The patient (and their legal guardian if appropriate) must fully understand the study, agree to take part voluntarily, and sign a written consent form. A separate consent form for EGFR testing is also required before screening begins. - Patients who are between 2 and 18 year...

Who might be able to join this trial: - Your blood counts, liver function, kidney function, and blood clotting results must meet certain healthy levels as measured by routine lab tests (confirm with trial site for exact values). - Your heart must be functioning normally. - You are expected to live for at least 12 weeks...

**Who might be able to join this trial:** - People aged between 18 and 80 years old - People whose overall health status falls within a moderate risk category as assessed by an anaesthesiologist (known as ASA physical status II or III — confirm with trial site for what this means in your situation) - People whose kidne...

Who might be able to join this trial: - People who have been diagnosed with metastatic kidney cancer (cancer that has spread beyond the kidney), confirmed by a tissue sample, with a tumour type that is either clear cell, papillary, chromophobe, or unclassified. Tumours with sarcomatoid features are also accepted. - Peo...

**Who might be able to join this trial:** **At the start of the trial:** - You are 18 years of age or older - You have kidney cancer (renal cell carcinoma) that has spread or cannot be removed or cured by surgery or radiation - Your kidney cancer has been confirmed by a lab test and is mainly the "clear cell" type - Y...

**Who might be able to join this trial:** - People aged 18 to 75 years of any gender - People who have been confirmed through laboratory testing of tissue or cell samples to have a type of kidney cancer called clear cell renal cell carcinoma that cannot be removed by surgery or has spread to other parts of the body -...

**Who might be able to join this trial:** - You have been diagnosed with kidney, bladder, breast, or lung cancer, confirmed by a doctor - You are within about two weeks of starting a specific type of immunotherapy treatment (called a PD-1 or PD-L1 checkpoint inhibitor), either on its own or alongside other treatments -...

Who might be able to join this trial: - You are between 18 and 70 years old (inclusive), regardless of gender - Your doctor expects you to live for more than 12 weeks - You are generally able to carry out normal daily activities, or have only mild limitations due to your illness (confirm with trial site) - You have bee...

Who might be able to join this trial: - People who have been diagnosed with a type of kidney cancer called renal cell carcinoma (with or without certain tissue features), confirmed by a laboratory test on a tissue sample. - People who are at least 18 years old at the time of signing the consent form. - People who are w...

**Who might be able to join this trial:** - People who have read and understood the study information and have agreed to take part by signing a consent form - Men or women between 18 and 75 years old at the time of signing the consent form - People whose scans (MRI or CT) show a stage T1 kidney tumour (an early-stage...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with advanced kidney cancer (renal cell carcinoma) that is being treated with a standard combination of two immunotherapy drugs - People who are willing and able to sign a written consent form agreeing to ta...

**Who might be able to join this trial:** - Adults aged 18 or older (male or female) - People with a laboratory-confirmed diagnosis of clear cell renal cell carcinoma (a specific type of kidney cancer) that has spread, cannot be surgically removed, or is advanced — and where all standard treatments have already been t...