Liver Cancer
Plain English clinical trial information, updated daily from ClinicalTrials.gov and public government registries. Not medical advice.
How these figures are counted
- Trials on record is every trial tagged to this condition at any stage, except those withdrawn before starting or terminated early. Most are completed rather than ongoing, so this is a measure of research history, not of current activity. It is also smaller than the sitewide "trials tracked" figure, which does include withdrawn and terminated trials.
- Recruiting now counts only trials whose registry status is "Recruiting". Trials listed as not yet recruiting or enrolling by invitation are excluded, so this understates how many may open to new participants soon.
- Australian sites counts trials counted under "Recruiting now" that list at least one Australian site. A site being listed does not mean it is currently enrolling, and Australian trials registered only on ANZCTR are not counted yet, so this understates local availability.
- Phase 3 trials counts trials counted under "Recruiting now" that are at Phase 3.
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Understanding Liver Cancer
Liver cancer is a condition where abnormal cells grow and multiply in the liver, forming a tumour. The most common type is called hepatocellular carcinoma, which starts in the main cells of the liver itself. Less commonly, cancer can begin in the bile ducts inside the liver, which is called cholangiocarcinoma. The liver is a large organ in the upper right side of your abdomen that performs important jobs like filtering the blood and helping with digestion. When cancer develops there, it can affect how well the liver is able to do these tasks.
In Australia, liver cancer is more common in some groups than others. People who have had long-term hepatitis B or hepatitis C infection are at higher risk, as are people with cirrhosis, which is scarring of the liver often related to alcohol use or other liver diseases. Liver cancer is also more common in men than women, and rates are higher among Aboriginal and Torres Strait Islander people and people from some Southeast Asian and Pacific Islander backgrounds. Overall, diagnoses have been increasing in Australia over recent decades.
Treatment options depend on a number of factors, including the size and location of the tumour, how well the liver is functioning, and whether the cancer has spread to other parts of the body. Some people may be offered surgery to remove the tumour, or in some cases a liver transplant. Other options can include ablation, which uses heat or cold to destroy tumour cells, or a procedure called TACE that delivers treatment directly to the blood vessels feeding the tumour. Radiation therapy, targeted drug therapies, and immunotherapy are also used in some situations. A specialist medical team will discuss the options that are most relevant to an individual's specific situation.
This overview is an AI generated summary written from public medical sources and checked on a sample basis. It is general information, not medical advice or a diagnosis. Always speak with your doctor about your situation. How we use AI
Can you access treatment for Liver Cancer in Australia right now? Here's what's publicly known.
- 5 PBS-subsidised medicines are mapped to Liver Cancer on the Pharmaceutical Benefits Scheme, listed below. Your doctor can advise whether a PBS-subsidised option is appropriate for you.
- 10 clinical trials currently recruiting at Australian sites for Liver Cancer.
Information on this site does not constitute medical advice. Data is sourced from publicly available government registries. Always consult your doctor before making any health decisions. Trial status should be verified directly with the trial site.
PBS-subsidised medicines for Liver Cancer
5 medicines listed on the PBS for Liver Cancer. Filter by authority type, or open the full table below.
Full PBS medicines table 5 listed
These medicines are listed on the Pharmaceutical Benefits Scheme (PBS) for the specific indications shown. A listing does not mean a medicine is right for you; your doctor decides what is appropriate. Prices shown are the PBS-determined dispensed price. Most patients pay only the standard co-payment, up to AU$25.00 per script (general) or AU$7.70 (concession or Safety Net) in 2026, with the Australian Government subsidising the rest.
| Medicine | Brand(s) | Listed for | ||
|---|---|---|---|---|
| Atezolizumab | Tecentriq, Tecentriq SC | hepatocellular carcinoma Advanced (unresectable) Barcelona Clinic Liver Cancer Stage B or Stage C | AU$4723.15 | Streamlined authority |
| Durvalumab | Imfinzi | hepatocellular carcinoma Advanced (unresectable) Barcelona Clinic Liver Cancer Stage B or Stage C | AU$860.99 | Streamlined authority |
| Lenvatinib | Lenvima | hepatocellular carcinoma Advanced (unresectable) Barcelona Clinic Liver Cancer Stage B or Stage C | AU$2000 | Streamlined authority |
| tremelimumab | Imjudo | hepatocellular carcinoma Advanced (unresectable) Barcelona Clinic Liver Cancer Stage B or Stage C | AU$16560.18 | Streamlined authority |
| Sorafenib | Nexavar | hepatocellular carcinoma Advanced Barcelona Clinic Liver Cancer Stage B or Stage C | AU$1993.7 | Streamlined authority |
Source: Pharmaceutical Benefits Scheme (PBS), © Commonwealth of Australia. Data used and redistributed under permission; not modified from its original wording where displayed verbatim.
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Become a founding memberResearch pipeline
Where trials for Liver Cancer currently sit in the development pipeline. The funnel shape shows how few drugs reach later phases in general; the counts are this condition's actual trial numbers.
Most active research sponsors
Organisations with the most recruiting trials for Liver Cancer.
Where trials are running
Clinical trial sites for Liver Cancer by country. Australia is highlighted.
Clinical trials for Liver Cancer
Showing 621 of 621 trials
The plain English eligibility text on each trial below is an AI generated summary of the official criteria, checked on a sample basis. How we use AI
🇦🇺 NCT04075305 · UMC Utrecht Not Applicable · 9 countries
Who might be able to join this trial: - People who are scheduled to have, or have already had, imaging or treatment on a machine called an MR-Linac (a combined MRI scanner and radiation therapy machine) - People who are willing and able to sign a written consent form agreeing to take part - People who are 18 years of a...
🇦🇺 NCT04455932 · Concord Repatriation General Hospital Not Applicable · 2 countries
**Who might be able to join this trial:** - You have been diagnosed with cirrhosis (scarring of the liver) from any common cause, AND your liver is difficult to see clearly on an ultrasound scan. - Your cirrhosis has been confirmed in at least one of these ways: through a liver biopsy, through past serious liver compl...
🇦🇺 NCT05428735 · Maastricht University Not Applicable · 9 countries
**Who might be able to join this trial:** - People who have colorectal cancer that has spread to the liver (liver metastases) that cannot currently be fully removed by surgery, or may only potentially be removable, and where the remaining healthy liver after surgery would be too small (less than 30%, or less than 40%...
🇦🇺 NCT06252753 · AstraZeneca Not Applicable · 22 countries
**Who might be able to join this trial:** - People who are 18 years of age or older and considered a legal adult in their country at the time they enter the study - People who have been confirmed by their treating doctor to have a primary liver or bile duct cancer (specifically, unresectable hepatocellular carcinoma o...
🇦🇺 NCT06478693 · Myeloid Therapeutics Phase 1 · 3 countries
**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed (confirmed by tissue sample) with advanced, recurrent, metastatic, or inoperable liver cancer (HCC) — or, for one part of the trial, possibly other tumour types that express a protein called GPC3 (confirm with tr...
🇦🇺 NCT06921785 · AstraZeneca Phase 3 · 20 countries
**Who might be able to join this trial:** - You have liver cancer (HCC) that has spread to other parts of the body, cannot be surgically removed, or is at an advanced stage - You are in generally good physical condition and able to carry out daily activities with little or no restriction (confirmed by a doctor's asses...
🇦🇺 NCT06923761 · Grey Wolf Therapeutics Phase 2 · 4 countries
**Who might be able to join this trial:** - People who are 18 years of age or older. - People who are generally well enough to carry out light activity or desk work (a doctor would assess this using a standard scale). - People who are willing to allow the trial team to access stored tumour tissue, past scan results, a...
🇦🇺 NCT07291076 · Bristol-Myers Squibb Phase 2 · 14 countries
Who might be able to join this trial: - People who have been diagnosed with locally advanced or inoperable liver cancer (hepatocellular carcinoma), confirmed through a tissue biopsy or sample. - People whose general health and ability to carry out daily activities meets a specific standard, rated 0 or 1 on a medical sc...
🇦🇺 NCT07391670 · AstraZeneca Phase 1 · 5 countries
Who might be able to join this trial: - You are in good general health and able to carry out daily activities with little or no difficulty (as measured by a standard health scale called ECOG, scored 0 or 1). - You are expected to live for at least 12 weeks from the time of joining the trial. - Your heart, liver, kidney...
🇦🇺 NCT07628751 · University Health Network, Toronto Not Applicable · 2 countries
Who might be able to join this trial: - People who have been diagnosed with a single, new liver cancer (hepatocellular carcinoma) measuring 8 cm or smaller, confirmed by tissue sample or imaging scan, at an early stage (BCLC stage 0 or A). - People with a previous liver cancer diagnosis may still be considered, provide...
🇦🇺 NCT01939223 · Bayer Phase 3 · 14 countries
**Who might be able to join this trial:** - You have been diagnosed with a type of colorectal cancer called adenocarcinoma (a cancer that started in the colon or rectum). - Your cancer had spread (Stage IV), but only to the liver — not to other parts of the body. - You have had surgery with the goal of fully removing...
NCT01050296 · St. Jude Children's Research Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have a suspected or known diagnosis of neuroblastoma, osteosarcoma, Ewing sarcoma, or soft tissue sarcoma, with a tumour that can be surgically removed — tissue, bone marrow, or blood samples may be collected at different points such as biopsy, surgery, or if the cance...
NCT01280825 · University of Chicago Not Applicable · 1 country
**Who might be able to join this trial:** - People who receive ongoing outpatient care at the University of Chicago Medical Center under a doctor who is participating in this trial - People who are 18 years of age or older - People with a life expectancy of at least 3 years - People who are currently taking between 1 a...
NCT01479608 · Oslo University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with bowel cancer (colon or rectal cancer) that has been confirmed by a tissue sample (biopsy). - Scans (PET/CT and CT or MRI of the chest, abdomen, and pelvis) show the cancer has not spread outside the liver, and there is no sign of the original can...
NCT01762813 · Helse Stavanger HF Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with colorectal cancer, either in its original location or that has spread to the liver, where the treatment plan includes surgery with the goal of curing the condition - People aged 18 or older - People who have agreed to take part and provided wri...
NCT02172651 · Dana-Farber Cancer Institute Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colon cancer (confirmed by tissue testing) that has not spread to distant parts of the body (stage I, II, or III), and who are planning to have surgery to remove the tumor. - People who have been diagnosed with colon cancer (confirmed by t...
NCT02174549 · Teclison Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who have a well-differentiated neuroendocrine tumour (NET) that has spread to the liver, where the liver is the main site of disease, regardless of where the original tumour started or whether the tumour is producing hormones. - People whose liver tumours, while any s...
NCT02185443 · University of Sao Paulo Phase 2 · 1 country
**Who might be able to join this trial:** - People who have a performance score (a measure of general health and ability to carry out daily activities) of 70 or above on the Karnofsky Performance Scale, indicating they are reasonably functional - People who have between 1 and 4 tumours that have spread to the liver, w...
NCT02215889 · Oslo University Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colorectal cancer (cancer of the colon or rectum) confirmed by a tissue biopsy. - People whose cancer has spread to the liver in a way that cannot be removed by surgery. - People whose scans (PET/CT) taken within 4 weeks before the transpl...
NCT02246634 · Imperial College London Not Applicable · 1 country
Who might be able to join this trial: - People who have a high-risk primary colorectal cancer (a new cancer in the colon or rectum that has not been treated before). - People whose CT scan shows no signs of cancer that has spread to the liver. - People who would be able to receive treatment if cancer in the liver were...
NCT02864485 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - The person must live in Canada. - The person must be in generally good physical condition and able to carry out daily activities, as measured by a standard health scoring system called the ECOG scale (scores 0–1, with brief dips to score 2 allowed at the doctor's discretion)...
NCT02885753 · Federation Francophone de Cancerologie Digestive Phase 3 · 2 countries
**Who might be able to join this trial:** - You have been diagnosed with colorectal cancer (bowel cancer) that has spread to the liver, confirmed by a tissue sample (biopsy) - You have at least one liver tumour that can be measured using standard scanning methods - Your cancer has only spread to the liver, or if it ha...
NCT02886104 · Sixth Affiliated Hospital, Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have at least one liver tumour that has been confirmed by laboratory tissue testing to be a type of cancer called adenocarcinoma that has spread (metastasised) to the liver. - People who have been confirmed by laboratory tissue testing to have adenocarcinoma of the col...
NCT02917707 · Da Fu Not Applicable · 1 country
Who might be able to join this trial: - People aged 75 or younger with colorectal cancer (bowel cancer) that has been confirmed by a laboratory test on a tissue sample - People whose major organs (such as the heart, lungs, kidneys, and liver) are functioning without severe problems - People with a WHO performance statu...
NCT02920554 · Saint Vincent's Hospital, Korea Not Applicable · 1 country
Who might be able to join this trial: - People who have gallbladder cancer that has reached a certain stage (called T2 or T3), as seen on a CT scan before surgery - People who have been confirmed by laboratory testing (looking at tissue samples) to have T2 or T3 gallbladder cancer after having their gallbladder removed...
NCT03253536 · Ludwig-Maximilians - University of Munich Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma), either confirmed by a tissue sample or by medical imaging - People who have 1 to 3 liver tumours that are suitable for a type of targeted radiation treatment called stereotactic body radiation therapy (S...
NCT03401294 · University of Saskatchewan Phase 2 · 1 country
Who might be able to join this trial: - Adults aged between 18 and 70 years who have been diagnosed with a specific type of bowel cancer (adenocarcinoma or poorly differentiated carcinoma of the colon or rectum) that has spread to the liver only, cannot be removed by surgery, and has not spread to any other part of the...
NCT03494946 · Oslo University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been confirmed by laboratory testing to have a type of bowel cancer (adenocarcinoma) that started in the colon or rectum. - People whose cancer has spread to the liver, but where surgery to remove the liver tumours is not possible. - People who have no signs...
NCT03612726 · Humanity & Health Medical Group Limited Not Applicable · 3 countries
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that cannot be removed by surgery. - People who are able to understand the study information and sign a written consent form agreeing to take part, following the rules of the institution running the trial...
NCT03686709 · University of Tennessee Not Applicable · 1 country
Who might be able to join this trial: - People who are already scheduled to receive Y90 radioembolization therapy using SIR-Spheres or TheraSpheres (a type of internal radiation treatment) - People who are able to stay at the hospital for extra PET/CT scans (a type of medical imaging) after their treatment - People who...
NCT03715517 · University of Manitoba Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older, of any gender, with no upper age limit. - People rated as relatively healthy to moderately unwell under a standard pre-surgery health classification system (ASA physical status I to III). - People scheduled for planned (non-emergency) open abdominal liver...
NCT03812874 · TCM Biotech International Corp. Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with hepatocellular carcinoma (liver cancer) that cannot be removed by surgery, classified as intermediate-stage (BCLC stage B, or Child-Pugh class A or B with large or multiple tumours, and no spread to blood vessels or outside the liver), who have complete...
NCT03894917 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue sample or imaging scan such as a CT or MRI. - People aged 18 years or older. - People whose liver cancer is at an advanced stage and cannot be surgically removed, as determ...
NCT03895359 · London Health Sciences Centre Research Institute OR Lawson Research In... Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a primary liver or bile duct cancer confirmed by a tissue test (biopsy or pathology report). - People who have cancer that has spread to the liver (from a non-lymphoma cancer), confirmed by a tissue test. - People whose liver lesions appea...
NCT03897543 · Abivax S.A. Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People who are generally well enough to carry out daily activities with little or no limitation (as measured by a standard health scale called ECOG, score 0 or 1) - People who have been diagnosed with liver cancer (HCC) through a tissue sample, wher...
NCT03899428 · Humanity & Health Medical Group Limited Phase 2 · 1 country
**Who might be able to join this trial:** - People who test positive for hepatitis B surface antigen (HBsAg) with levels at or above a certain threshold in their blood - People who are 18 years of age or older at the time of signing consent - People who are able to understand and follow the study requirements, and who...
NCT03942328 · Mayo Clinic Phase 2 · 1 country
Who might be able to join this trial: - People aged 18 years or older. - People with liver cancer (hepatocellular carcinoma, or HCC) confirmed by tissue testing and/or medical imaging (this applies to Group 2 of the study). - People with a type of bile duct cancer found inside the liver (intrahepatic cholangiocarcinoma...
NCT03959800 · University of Pittsburgh Not Applicable · 1 country
Who might be able to join this trial: - You were treated (or are currently being treated) for a liver tumor as a child or young person under the age of 21, whether the tumor was cancerous or non-cancerous. - You are a biological (blood-related) parent or biological sibling of a child who meets the above criteria. Who...
NCT04143516 · Memorial Sloan Kettering Cancer Center Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with cancer that has spread (metastasised) to the liver from another part of the body - People whose cancer is either confined to the liver, or has spread only to a limited number of sites outside the liver that have been stable or controlled fo...
NCT04150744 · Second Affiliated Hospital, School of Medicine, Zhejiang University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue or cell testing - People whose liver cancer has been classified at a mid-to-advanced stage (BCLC stage B or C) - People with a...
NCT04204850 · University Health Network, Toronto Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has come back, confirmed by a tissue or cell test. - People who previously had a liver transplant as a curative treatment for their liver cancer. - People whose returned cancer cannot...
NCT04339036 · Abramson Cancer Center at Penn Medicine Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with a specific type of slow-growing tumour called a neuroendocrine tumour (grade 2 or 3) that has spread to the liver and cannot be removed by surgery - You have at least one tumour in the liver that is larger than 1 cm in size - Most of your tumour...
NCT04340986 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been receiving care in a Nephrology (kidney) department since 2015 - People with cholangiocarcinoma (a type of cancer affecting the bile ducts) that has been confirmed through tissue or cell testing, at any stage of the disease...
NCT04348838 · Centre Hospitalier Universitaire, Amiens Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been newly diagnosed with hepatocellular carcinoma (a type of liver cancer) - People with a suspected case of this type of liver cancer, regardless of the cause, stage, or treatment involved - People with a known diagnosis of this liver cancer who are receivin...
NCT04365751 · Chinese PLA General Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults over 18 years old, of any gender - People without liver scarring (cirrhosis) who have had liver cancer confirmed by a tissue biopsy within the past month before surgery, OR people with liver scarring whose liver cancer has been identified using a specialised MRI or CT...
NCT04380545 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - The patient (or their legal guardian, for those under 18) must be willing and able to give written consent to participate, and must be able to understand the study and its risks — including patients with a history of major psychiatric illness, as assessed by the trial team....
NCT04390724 · Northwestern University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), either confirmed by a tissue biopsy or meeting specific imaging and blood test criteria set by a leading liver disease organisation (AASLD) - People whose liver function falls into a categor...
NCT04430452 · Mary Feng, MD Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) — either confirmed by tissue sample, or in some cases by imaging scans that meet specific medical guidelines — and whose cancer has continued to grow during or after treatment with certain im...
NCT04472767 · University of California, Irvine Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) based on tissue testing or imaging scans - People who have at least one liver tumour that can be treated with a procedure called TACE (a targeted treatment delivered directly to the tumour throu...
NCT04491929 · Aarhus University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with colorectal cancer that has spread (metastasized) to the liver, and the liver is the main area affected. - Your liver metastasis has been confirmed either through a tissue/cell sample (biopsy) or through scans and clinical assessment. - Your liver...
NCT04499833 · Centro Hospitalar de Lisboa Central Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with liver cancer (hepatocellular carcinoma) that is linked to liver scarring (cirrhosis) - You are between 18 and 70 years old - The total size of all your tumours combined is less than 500 cm³ (confirm with trial site) - You have fewer than 10 separate t...
NCT04512833 · Beijing 302 Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - A surgeon, radiologist, or oncologist has diagnosed the person with primary hepatocellular carcinoma (liver cancer) following international guidelines, or the diagnosis has been confirmed by a tissue sample (biopsy) - The person is either unable to have other treatments or h...
NCT04512846 · Beijing 302 Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - A surgeon, radiologist, or oncologist has diagnosed the person with primary liver cancer (hepatocellular carcinoma, or HCC), either through imaging or a tissue sample, following international guidelines - The person has a single liver tumour that measures between 5 and 10 cm...
NCT04556214 · Oslo University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been confirmed through a tissue biopsy to have a specific type of liver cancer called intrahepatic cholangiocarcinoma (iCCA) - This is either your first time being diagnosed with iCCA, or the cancer has come back only in the liver after a previous liver surgery - Do...
NCT04587739 · University Hospital, Lille Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a type of liver cancer called hepatocellular carcinoma, confirmed either by a tissue sample (biopsy) or by meeting recognised medical imaging guidelines - People whose cancer appears as a single tumour measuring between 3 and 8 centimetres...
NCT04601428 · Koo Foundation Sun Yat-Sen Cancer Center Early Phase 1 · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either confirmed by a tissue sample (biopsy) or by MRI or CT scan showing typical signs of liver cancer alongside liver cirrhosis - People whose liver cancer is classi...
NCT04616495 · Hospital Universitario La Fe Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older (confirm upper age limit with trial site, as it appears incomplete in the source criteria) - People with a good general health and activity level, as measured by a standard medical scale called ECOG, scoring 0 or 1 (meaning fully active or able to carr...
NCT04617522 · Gilead Sciences Phase 1 · 4 countries
**Who might be able to join this trial:** - You have been diagnosed with an advanced or spreading solid tumor cancer that has been confirmed by a tissue sample (biopsy). - You are generally able to care for yourself and carry out daily activities, even if you cannot do heavy physical work (based on a standard doctor's...
NCT04634357 · Eureka Therapeutics Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatoblastoma (HB), hepatocellular neoplasm not otherwise specified (HCN-NOS), or hepatocellular carcinoma (HCC), confirmed by a tissue sample, with a specific protein marker (AFP) above 100 ng/mL in their blood at the time of screening....
NCT04657042 · University of Virginia Not Applicable · 1 country
**Who might be able to join this trial:** **For people with lung or liver cancer:** - People aged 21 or older - People who have a primary or secondary (spread-from-elsewhere) tumour located in the lungs or liver - People whose tumour(s) measure less than 7 cm across - People whose treating radiation specialist has alr...
NCT04665388 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a cancer linked to the Epstein-Barr virus (EBV), such as nasopharyngeal cancer (a type of cancer in the back of the nose and throat). - People who have been diagnosed with a cancer linked to the human papillomavirus (HPV), including certai...
NCT04678583 · Technische Universität Dresden Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with colorectal cancer that has a specific gene change called a RAS mutation (either KRAS or NRAS) - People whose colorectal cancer has spread to the liver (one or more spots) - People for whom surgeons have planned a complete surgical removal of the liver tu...
NCT04687631 · Fudan University Phase 3 · 1 country
**Who might be able to join this trial:** - The person's primary cancer has been confirmed by tissue testing as colorectal adenocarcinoma (a type of bowel cancer). - Liver metastases (cancer that has spread to the liver) have been assessed by a specialist medical team as not suitable for surgery at this stage. - Speci...
NCT04745390 · London Health Sciences Centre Research Institute OR Lawson Research In... Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a primary liver or bile duct cancer confirmed by a pathology test, OR liver tumours that have spread from another cancer (not lymphoma) confirmed by pathology, OR liver tumours that look like spread cancer on scans in someone already known...
NCT04770207 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with a solid advanced malignant (cancerous) tumour - People who are between 18 and 99 years of age - People whose doctors estimate they have a life expectancy of more than three months Who may not be able to join: - People who have a benign (non-ca...
NCT04777942 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years - People diagnosed with early-stage liver cancer (BCLC Stage A) that has a high risk of coming back after treatment - People whose liver cancer can be removed through surgery - People whose liver is functioning at a level classified as Chil...
NCT04798898 · University of Aarhus Not Applicable · 1 country
Who might be able to join this trial: - People with colorectal cancer that has spread to the liver and who are scheduled to have surgery to remove those liver tumours. - People who have at least one liver tumour that is 3cm or larger in size. - People who are in generally good physical health, able to carry out daily a...
NCT04803318 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
Who might be able to join this trial: - People aged between 18 and 85 years old - People who have an advanced solid tumor (a type of cancer) that has come back or has not responded to previous treatment - People whose doctors estimate they are likely to live for more than three months Who may not be able to join: - Pe...
NCT04803994 · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Phase 3 · 6 countries
**Who might be able to join this trial:** - Adults aged 18 or older who have signed a consent form to participate - People with a confirmed diagnosis of hepatocellular carcinoma (a type of liver cancer), confirmed by tissue sample or specific imaging scans - People whose liver cancer is at an intermediate stage — mean...
NCT04806464 · CNBG-Virogin Biotech (Shanghai) Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People diagnosed with advanced primary liver cancer (specifically hepatocellular carcinoma, intrahepatic cholangiocarcinoma, or a combined type) where standard treatments have stopped working, were not tolerated, or no standard treatment exists. Note: in the second part of t...
NCT04823403 · Gustave Roussy, Cancer Campus, Grand Paris Phase 1 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older. - People who are able to understand, sign, and date a consent form before any trial procedures begin. - People who are willing and able to follow the study schedule, attend visits, and provide the required samples as set out in the trial plan. - Peop...
NCT04842812 · Second Affiliated Hospital of Guangzhou Medical University Phase 1 · 1 country
**Who might be able to join this trial:** - You have advanced cancer that has not responded to currently available treatments - Doctors expect you to live for more than 12 weeks - Your heart, lungs, liver, and kidneys are all working well enough (confirm with trial site) - A tissue sample (biopsy) or fluid sample from...
NCT04864054 · Eureka Therapeutics Inc. Phase 2 · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that cannot be surgically removed, has come back, or has spread to other parts of the body — confirmed by a tissue biopsy. - People whose liver cancer tumors test positive for a protein calle...
NCT04868149 · The University of Hong Kong Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a malignant (cancerous) liver tumour and are being considered for a specific major liver surgery that removes a large portion of the liver - People who have given their consent to take part - People aged 18 or older - People whose remainin...
NCT04906434 · Abbisko Therapeutics Co, Ltd Phase 1 · 3 countries
**Who might be able to join this trial:** - Adults between 18 and 75 years old (exact age range may vary depending on local rules). - For the dose-finding phase of the trial: people with advanced solid tumours (confirmed by tissue or cell testing) that have grown or spread despite standard treatment, or where no stand...
NCT04912765 · National Cancer Centre, Singapore Phase 2 · 1 country
**Who might be able to join this trial:** **For people with liver cancer (hepatocellular carcinoma / HCC):** - People who have been newly diagnosed with liver cancer, or whose liver cancer has come back, confirmed by a biopsy or by standard medical imaging criteria, where surgery (with or without ablation) is planned...
NCT04933435 · Duke University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (liver cancer) either through a tissue biopsy or through a CT or MRI scan using a specific liver imaging assessment system - People who are 18 years of age or older - People whose general physical functioning falls...
NCT04946773 · University of Oxford Not Applicable · 1 country
Who might be able to join this trial: - You are willing and able to agree to take part in the study by giving your consent. - You are male or female, aged between 18 and 75 years old. - *(Malignancy group only)* You have been diagnosed with, or doctors suspect you may have, a cancer affecting the liver or bile ducts. -...
NCT04952272 · Second Affiliated Hospital of Guangzhou Medical University Phase 1 · 1 country
Who might be able to join this trial: - People who have a solid advanced cancer (a tumour that has spread or cannot be removed) - People who are between 18 and 80 years old - People who are expected to live for more than three months Who may not be able to join: - People who have a non-cancerous (benign) tumour - Peop...
NCT04965454 · Queen's Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older (there is no upper age limit) - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed either by tissue sample or by imaging scans, following specific cancer network guidelines - People whose cancer cannot be t...
NCT04982653 · M.D. Anderson Cancer Center Phase 2 · 1 country
Who might be able to join this trial: - You are having planned surgery to remove part of your liver because of cancer (either a cancer that started in the liver or one that spread there from elsewhere) - Your surgery is scheduled in advance and is not an emergency - You are 18 years of age or older - Your surgeon plans...
NCT04988945 · The University of Hong Kong Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to give written agreement to participate, including following all study rules and procedures - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that cannot be surgically removed, confirmed either by tissue sample or by s...
NCT04993131 · Oslo University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Imaging results strongly suggest a type of bile duct cancer called perihilar cholangiocarcinoma (pCCA) (confirm with trial site) - The cancer may involve certain blood vessels near the liver, but must not have blocked the main portal vein outside the liver - The cancer may i...
NCT04996914 · RWTH Aachen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either through a tissue sample or medical imaging - People aged between 18 and 80 years old - People who have between 1 and 3 liver tumours - People whose tumour is at least 4 cm in s...
NCT05010681 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older at the time of joining the study. - People who have signed a written consent form agreeing to take part. - People who have been diagnosed with liver cancer (hepatocellular carcinoma) or bile duct cancer originating in the liver (intrahepatic cholangio...
NCT05035108 · Sir Run Run Shaw Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer, stones in the liver's bile ducts (hepatolithiasis), or a non-cancerous liver tumour, and whose doctors have determined that surgery to remove part of the liver is the right treatment - People whose liver is functioning at a l...
NCT05039632 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You have cancer that has spread (metastasized) to the lung, liver, or soft tissue from any original cancer type, and it cannot be cured with local treatments alone. - You may have had one previous treatment with a type of immunotherapy called anti-PD-1/L1 therapy. - You have...
NCT05047510 · Chinese Academy of Sciences Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) - People who are planned to have surgery to remove part of the liver (hepatectomy) - People whose liver is functioning at a level classified as Child-Pugh A or B (a measure of liver health — confirm w...
NCT05057845 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form agreeing to participate in the study. - People who are 18 years of age or older at the time of joining the study. - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that cannot be surgically removed or...
NCT05068531 · Centre hospitalier de l'Université de Montréal (CHUM) Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with stage IV colon or rectal cancer that has spread to the liver only, and your doctors are planning surgery to remove part of your liver with the goal of curing you - Instead of, or in addition to liver surgery, yo...
NCT05072041 · Next Biomedical Co., Ltd. Not Applicable · 1 country
Who might be able to join this trial: - Adults between the ages of 19 and 79 years old - People who have signed a consent form agreeing to take part in the trial - People diagnosed with liver cancer (hepatocellular carcinoma) confirmed by MRI, contrast-enhanced CT scan showing a liver lesion larger than 1 cm, or by tis...
NCT05095714 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years old or older - You must have been attending a liver screening program for at least 6 months at a specialist liver centre - You must have cirrhosis (scarring of the liver) confirmed either by a biopsy or by other accepted medical tests - A recent scan (within...
NCT05098847 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of joining the study. - People who have liver metastases (cancer that has spread to the liver from another part of the body) that cannot be removed by surgery. - People whose cancer continued to grow or stopped responding to at least one p...
NCT05143619 · M.D. Anderson Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - Doctors who have completed their radiology residency training (not currently in training) - Radiologists who have specialized training in imaging of the abdomen, either currently undergoing or already completed - Radiologists who have experience reading liver scans, regardless of...
NCT05150145 · Guizhou Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have given written consent to take part before treatment begins, including consent to radiation and medication - People aged 18 to 70 years old, of any gender - People who have been newly diagnosed with small cell lung cancer (SCLC), confirmed by a tissue or cell s...
NCT05168163 · Academic and Community Cancer Research United Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed either by a tissue sample or through established clinical guidelines. - People whose liver cancer is advanced, has spread to other parts of the body, or cannot be surgical...
NCT05181826 · Helio Genomics Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with cancer, are in cancer remission, have a benign (non-cancerous) condition such as a benign tumor, diabetes, liver cirrhosis, chronic hepatitis B or C, or chronic obstructive pulmonary disease, or people...
NCT05185245 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
**Who might be able to join this trial:** - Your original colorectal (colon or rectal) cancer tumor was fully removed with surgery, leaving no cancer cells at the edges of the removed tissue - You have cancer that has spread to the liver that cannot be removed with surgery, either from the start or after previous live...
NCT05185505 · The Methodist Hospital Research Institute Phase 4 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older at the time of signing the consent form - People who have liver cancer (hepatocellular carcinoma, or HCC) that cannot be surgically removed and has spread beyond what is considered the Milan criteria (a set of size and number limits used in transplant...
NCT05185739 · University College, London Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a specific type of liver cancer called Hepatocellular Carcinoma (HCC) — confirmed by imaging, tissue sample, or cell sample — and whose cancer is considered suitable for surgical removal (note: certain subtypes called fibrolamellar and mix...
NCT05186116 · Azienda Ospedaliero-Universitaria di Modena Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with colon or rectal cancer (inside the abdominal cavity) confirmed by a tissue sample (biopsy) - Your original tumor meets specific pathology requirements: it was at an early-to-moderate stage, was fully removed with...
NCT05195710 · M.D. Anderson Cancer Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who have colorectal cancer that has spread to the liver, where the tumour is on the borderline of being removable by surgery, or currently cannot be safely removed because there is not enough healthy liver remaining — and where the surgical team believes surgery with...
NCT05199259 · Helio Genomics Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older, of any sex. - People who have cirrhosis, or who meet the medical guidelines for regular liver cancer (HCC) monitoring. - People who have been clinically diagnosed with liver cancer (HCC), or people who have been checked and found not to have liver ca...
NCT05201404 · Can-Fite BioPharma Phase 3 · 9 countries
**Who might be able to join this trial:** - Adults aged 18 or older of any sex - People who have been diagnosed with hepatocellular carcinoma (liver cancer), confirmed either by tissue biopsy (for those without liver scarring/cirrhosis) or by a recognised specialist guideline process (for those with cirrhosis) - Peopl...
NCT05215535 · Vastra Gotaland Region Not Applicable · 1 country
Who might be able to join this trial: - Adults who are over 18 years of age - People who have been diagnosed with suspected rectal cancer (either through a camera examination of the bowel or based on clinical assessment) and are being considered for further imaging tests - People who are able to understand the trial in...
NCT05223816 · Virogin Biotech Canada Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able and willing to give written consent to participate. - Adults aged 18 or older, of any sex. - People who are relatively well and able to carry out daily activities, based on a standard cancer performance scale (ECOG score of 0 or 1). - People in Cohort 2:...
NCT05240950 · Changhai Hospital Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who have been diagnosed with colorectal cancer that has spread to the liver, had surgery to remove the original colorectal cancer, and had complete surgical removal of the liver spread (and any other organ involvement),...
NCT05257590 · TaiRx, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older (20 or older for participants in Taiwan) - People who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed by a tissue sample, cell sample, or by specific imaging scans showing a liver tumour of 1 cm or larger - People whose liv...
NCT05263830 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 to 89 years old - People diagnosed with liver cancer (called hepatocellular carcinoma, or HCC) that developed alongside a chronic liver condition or scarring of the liver (cirrhosis), regardless of the underlying cause, diagnosed according to specific French medica...
NCT05265208 · Center Eugene Marquis Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged over 18 years old - People whose general health and ability to carry out daily activities meets a certain standard (a medical scoring system called ECOG gives a score of less than 2, meaning the person is reasonably active — confirm with trial site) - People who h...
NCT05304234 · University of Washington Phase 2 · 1 country
Who might be able to join this trial: - You have cirrhosis (scarring of the liver) from any cause, or you have a long-term hepatitis B infection - You are considered at high risk of developing liver cancer (hepatocellular carcinoma) - You are between 18 and 75 years old - You are able to understand and agree to partici...
NCT05304481 · Lukas Biomedical Inc. Phase 2 · 1 country
**Who might be able to join this trial:** **As a blood donor (providing blood for the treatment):** - People who are able to understand and sign the consent forms, knowing this is an experimental study - People aged 20 years or older - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC)...
NCT05314400 · London Health Sciences Centre Research Institute OR Lawson Research In... Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older, of any gender - People who have been diagnosed with colorectal cancer, confirmed by a tissue biopsy - People whose previous scans showed spots on the liver that may be cancer that has spread there - People who are willing and able to follow the study proc...
NCT05317819 · Polaris Group Phase 3 · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma/HCC), confirmed by imaging or tissue testing. - People who have already received at least one whole-body (systemic) treatment for liver cancer — or, for those with a specific liver function score (Chi...
NCT05321992 · McMaster University Not Applicable · 1 country
Who might be able to join this trial: - People who are 20 years of age or older and living in one of the 16 selected villages in Khon Kaen province, Thailand Who may not be able to join: - People who are 19 years old or younger - People who do not live in one of the 16 pre-selected villages in Khon Kaen province, Thai...
NCT05331911 · Kaohsiung Medical University Chung-Ho Memorial Hospital Phase 4 · 1 country
Who might be able to join this trial: - People between 20 and 80 years old. - People rated as ASA physical status class I, II, or III, meaning their overall health falls within a range accepted by the trial (confirm with trial site). - People who are having part of their liver surgically removed to treat liver cancer (...
NCT05359939 · University of Aarhus Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) - People who are 18 years of age or older Who may not be able to join: - People who do not wish to take part in the study - People whom the responsible investigator determines are not suitable...
NCT05366829 · Rutgers, The State University of New Jersey Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to take part in the study - People whose primary diagnosis is liver cancer (HCC), who are planned to receive radiation treatment, have not yet received any systemic (whole-body) drug treatment for liver cancer, and may have previously ha...
NCT05375370 · University Hospital, Rouen Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - You have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a special type of CT scan or MRI scan showing specific patterns of blood flow in the liver - You have been diagnosed with liver cancer confirmed by a tissue bi...
NCT05377034 · National Cancer Centre, Singapore Phase 2 · 4 countries
**Who might be able to join this trial:** - People who have been clearly diagnosed with hepatocellular carcinoma (a type of liver cancer) that is large or advanced within the liver, but has not spread outside the liver, and meets specific size or blood vessel involvement criteria as assessed by both the local site and...
NCT05398380 · Hospital Vall d'Hebron Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to sign a written consent form agreeing to take part in the study. - People aged between 18 and 70 years old at the time of joining the study. - People who are generally well or have only mild limitations in daily activity, as measured by a standar...
NCT05409482 · Meng Chao Hepatobiliary Hospital of Fujian Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People diagnosed with hepatocellular carcinoma (a type of liver cancer) either through standard clinical guidelines or confirmed by tissue or cell testing, with at least one tumour that is large enough to be measured on a scan...
NCT05412589 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have chosen to take part voluntarily and have signed a consent form - Adults aged 18 to 75, of any gender - People whose general physical functioning is rated at a mild-to-moderate level (ECOG score 0–2; confirm with trial site if unsure what this means) - People...
NCT05433467 · Northern Jiangsu People's Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are at least 18 years old and are willing to give formal consent to take part in the study - People who have been diagnosed with liver cirrhosis (scarring of the liver) for any reason, based on clinical assessment, imaging, or tissue testing before surgery - People who...
NCT05440708 · Tvardi Therapeutics, Incorporated Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand the study and are willing to give their consent and follow the study rules and procedures. - People who are 18 years of age or older at the time of giving consent. - People who have been diagnosed with liver cancer (HCC) that has spread or c...
NCT05440864 · University Health Network, Toronto Phase 2 · 3 countries
**Who might be able to join this trial:** - People who are able to understand and sign a written consent form - People who are older than 18 years of age - People who have been confirmed through a tissue test (biopsy) to have liver cancer (HCC) that can be surgically removed and is at an early or intermediate stage -...
NCT05443087 · UNICANCER Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 years or older - People with an advanced digestive cancer that has been confirmed by a tissue sample or scan, including certain types such as gastrointestinal stromal tumour (GIST), bowel cancer that has spread (mCRC), liver cancer (HCC), or certain types of p...
NCT05444478 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with primary liver cancer (hepatocellular carcinoma, or HCC) that is at an early to intermediate stage (classified as BCLC 0 to B), confirmed by pathology results. - People whose liver cancer has come back (recurred) and who have not yet received any cancer-...
NCT05475613 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent, and who can attend scheduled visits, follow the treatment plan, and complete required tests. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue, cell, or imaging...
NCT05476432 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old - People whose general health and ability to carry out daily activities meets a minimum standard (known as a KPS score of 70 or above — confirm with trial site if unsure what this means) - People who have been diagnosed with hepatocellu...
NCT05484908 · Third Affiliated Hospital, Sun Yat-Sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 65 years old - People who have been diagnosed with a long-term hepatitis B infection, confirmed by positive blood test results for more than 6 months - People who have been diagnosed with liver cancer and have been treated with immune checkpoint in...
NCT05486572 · VA Office of Research and Development Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with cirrhosis (scarring of the liver) from any cause, confirmed by a liver biopsy, imaging scans, clinical signs such as fluid in the abdomen or swollen veins in the food pipe, or a special liver stiffness test - People considered to be at hig...
NCT05488522 · Abramson Cancer Center at Penn Medicine Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that cannot be treated with surgery or ablation (a procedure that destroys cancer cells using heat, cold, or other methods), and where doctors have determined that a systemic (whole-body) treatm...
NCT05489289 · Akeso Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has not spread to other parts of the body - People who have had surgery aimed at completely removing the cancer, and this was the only cancer treatment received - People where no remai...
NCT05492136 · Hospital del Mar Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent before the surgical procedure begins, with the understanding that leaving the study at any time is allowed - People aged 18 or older - People whose general health and ability to carry out daily activities falls within a...
NCT05502198 · Linkoeping University Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with, or are suspected to have, liver cirrhosis (scarring of the liver), as determined by doctors at the Department of Gastroenterology and Hepatology at Linköping University Hospital — this may be based on different types of tests, scans, or symptoms, and...
NCT05516628 · National Cancer Centre, Singapore Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and mentally able to give written consent before any study-related testing begins. - Adults aged 21 to 90 at the time of signing the consent form. - People who are able to attend scheduled visits and follow study procedures. - People diagnosed with hep...
NCT05520788 · Tongji Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 65 years old, of any sex - People who have been diagnosed with stage IV hepatobiliary cancer (cancer of the liver, bile ducts, or gallbladder), confirmed by both imaging scans and tissue testing - People for whom palliative (comfort-focused) care is the...
NCT05528952 · Centre Hospitalier Universitaire de Besancon Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed an informed consent form agreeing to take part in the study - People whose liver cancer has been confirmed through a tissue sample (biopsy) - People whose cancer has spread, cannot be surgically removed, or is considered locally advanced - People who h...
NCT05534906 · University of Oxford Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing and able to give their consent to take part in the study - People aged 18 years or older - People who have been diagnosed with small liver cancer (hepatocellular carcinoma, or HCC) that is at an early stage — meaning 1 to 3 tumours each smaller than 3...
NCT05541601 · University of Oxford Not Applicable · 1 country
**Who might be able to join this trial:** - Adults over 18 years old of any gender - People who are willing and able to give their informed consent to take part in the study - People who have been diagnosed with cirrhosis (scarring of the liver) that is classed as Child-Pugh A or B (a measure of how well the liver is...
NCT05556642 · Children's Hospital Medical Center, Cincinnati Not Applicable · 1 country
**Who might be able to join this trial:** - People of any age who have a suspected or confirmed diagnosis of a rare liver tumour called relapsed/refractory hepatoblastoma (rrHBL), as determined by their treating cancer specialist or surgeon - Children under 6 years of age at the time of their first diagnosis who have...
NCT05588388 · Kamya Sankar Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to give written consent and follow the study requirements. - People who have been confirmed by lab testing (tissue or cell sample) to have extensive-stage small cell lung cancer (ES-SCLC) with liver spread (metastases) found on imaging at diagnosis. - Peo...
NCT05594927 · Beijing Shenogen Biomedical Co., Ltd Phase 3 · 1 country
Who might be able to join this trial: - Adults aged 18 or older, of any gender - People diagnosed with a type of primary liver cancer called hepatocellular carcinoma (HCC), confirmed either through medical imaging according to Chinese clinical guidelines or through a tissue/cell sample test - People whose liver cancer...
NCT05596630 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (HCC) that has not spread to the lymph nodes or other parts of the body. - People who have previously had surgery or a radiofrequency ablation procedure to treat their liver cancer, with no signs of the cancer coming back with...
NCT05608200 · Second Affiliated Hospital of Guangzhou Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - People diagnosed with advanced liver cancer (hepatocellular carcinoma, or HCC) at a specific advanced stage, confirmed either by a tissue sample or through clinical assessment - People whose liver cancer has come back after surgery or a procedure to destroy the tumor (ablati...
NCT05608213 · Second Affiliated Hospital of Guangzhou Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (liver cancer), confirmed by biopsy, lab testing of cells, or clinical diagnosis by a doctor - People whose liver cancer has stopped responding to a procedure called TACE (a treatment that delivers chemotherapy dir...
NCT05613478 · The First Affiliated Hospital with Nanjing Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - You are willing to take part and agree to sign a consent form. - You are 18 years of age or older (any gender can apply). - You have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed by a tissue sample, cell sample, or medical imaging. - Your liver cancer...
NCT05620706 · Shenzhen University General Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 40 and 70 years old. - People diagnosed with advanced liver cancer (confirmed by a tissue or cell sample) that cannot be treated with surgery or local treatments, and whose cancer has worsened or who could not tolerate standard treatments. - People whose...
NCT05620771 · Northwestern University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed according to recognised medical guidelines, with liver function falling within a specific accepted range (called Child-Pugh score A or B7). - People who have at least one tumour t...
NCT05629845 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with hepatocellular carcinoma (liver cancer) and have recently experienced bleeding from enlarged veins in the esophagus or stomach, where that bleeding was successfully treated within the past 4 weeks using standard procedures such...
NCT05652920 · OriCell Therapeutics Co., Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed by tissue or imaging tests - People whose liver cancer tumour tissue tests positive for a protein called GPC3, based on a lab test of a tissue sample taken within the past year (...
NCT05657873 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
Who might be able to join this trial: - People who are over 18 years old at the time of signing the consent form - People who have been confirmed through a tissue biopsy to have stage IV non-small cell lung cancer (a type of lung cancer), or whose stage III lung cancer has come back or spread after treatment with a dru...
NCT05661461 · Aadi Bioscience, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give informed consent and follow the study requirements for the whole duration of the trial. - People who are 18 years of age or older at the time of signing the consent form. - People who have been diagnosed (confirmed by tissue testing) w...
NCT05687747 · National University Hospital, Singapore Phase 1 · 1 country
Who might be able to join this trial: - People aged between 21 and 99 years old - People who have been diagnosed with a type of liver cancer called hepatocellular carcinoma (HCC), either confirmed by a tissue sample or by specialised medical scans following established guidelines - People who have not yet received any...
NCT05690048 · Michael Dill Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with hepatocellular carcinoma (liver cancer), confirmed by imaging or tissue biopsy - People whose liver cancer cannot be treated with surgery, a liver transplant, or local treatments aimed directly at the tumour...
NCT05692024 · Massachusetts General Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with stage I, II, or III colon or rectal cancer (confirmed by a laboratory test on tissue) and have finished standard treatment — including surgery, chemotherapy, and/or radiation — at least 2 months ago. - People aged 18 years or older. - People wh...
NCT05698459 · Binhui Biopharmaceutical Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old (inclusive) - People who have been diagnosed with primary or metastatic liver cancer, confirmed by a tissue or cell sample - People whose liver cancer has not responded to standard treatment, or for whom standard treatment is not suitable, or w...
NCT05700799 · University of California, San Francisco Not Applicable · 1 country
**Who might be able to join this trial:** - The patient must be under 18 years old and have already received a liver transplant. - The patient and/or their parent or legal guardian must be willing and able to sign a consent form agreeing to take part in the study. - The patient and/or their parent or legal guardian mus...
NCT05705219 · University of California, San Diego Not Applicable · 1 country
**Who might be able to join this trial:** - You have liver tumors (metastases) that spread from colorectal cancer (a low-grade type), confirmed by biopsy or medical scans, and you are about to start a new cancer treatment - You are 18 years old or older - You have at least one liver tumor that is at least 1 cm wide but...
NCT05718492 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue or cell testing, where the cancer is at an advanced stage that cannot be removed by surgery and/or has spread to other parts of the body. - People who have at least one...
NCT05727163 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - A diagnosis of colorectal cancer (specifically adenocarcinoma) confirmed by tissue testing - Liver metastases (cancer spread to the liver) confirmed by imaging or tissue testing - Liver metastases that a specialist team has determined cannot be surgically removed, based on s...
NCT05727787 · University of Kansas Medical Center Not Applicable · 1 country
**Who might be able to join this trial:** - The participant, or their legally authorised representative, must be able to understand the study and be willing to sign a written consent form. - Adults aged 18 years or older of any sex. - People who are generally well enough to carry out normal daily activities with littl...
NCT05733598 · Replimune, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older. - (For liver cancer patients) People with locally advanced, inoperable, returned, or spread liver cancer (hepatocellular carcinoma/HCC), confirmed by biopsy, lab testing, or imaging. - (For liver cancer patients) People whose liver cancer got worse w...
NCT05738616 · Wen Tianfu Phase 3 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years. - People diagnosed with hepatocellular carcinoma (a type of liver cancer) according to specific medical guidelines, or confirmed by laboratory tissue or cell testing. - People who have not previously received cancer treatment for this liv...
NCT05738980 · Beijing Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue biopsy or lab examination - People whose liver cancer is classified as an early-to-intermediate stage under China's national liver cancer staging guidelines (CNLC stag...
NCT05744219 · Jon Unosson Phase 3 · 1 country
Who might be able to join this trial: - People who are able to provide written consent to participate - Both men and women are eligible - People who weigh more than 50 kg - People who are 18 years of age or older - People who are scheduled to have a complex aortic surgery, liver removal surgery, or pancreatic removal s...
NCT05751343 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma) that cannot be removed by surgery and has reached an advanced stage - Your liver is functioning at a reasonable level, classified as Child-Pugh A or B (confirm with trial site) - You are generally able to ca...
NCT05755672 · Region Skane Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colorectal cancer that has spread to other parts of the body at the same time as the original diagnosis (known as synchronous metastatic colorectal cancer), and whose treatment is being planned with the goal of curing the cancer at Skåne Un...
NCT05775146 · AHS Cancer Control Alberta Phase 2 · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - You must be well enough to carry out daily activities, either fully or with some limitations (your doctor can confirm if your fitness level qualifies) - You must be able to sign a written consent form agreeing to take part - You must have be...
NCT05783908 · Centre Georges Francois Leclerc Not Applicable · 1 country
Who might be able to join this trial: - People who are at least 18 years old - People who are about to begin a type of radiation therapy (using a machine that combines MRI scanning with radiotherapy) for a cancerous tumour that moves with body functions such as breathing — most commonly in the pancreas, liver, kidneys,...
NCT05787197 · GERCOR - Multidisciplinary Oncology Cooperative Group Not Applicable · 1 country
**Who might be able to join this trial:** - People who have given written consent and are willing to take part in all study activities for the full duration of the trial - People who are 18 years of age or older - People whose colorectal cancer has been confirmed by laboratory testing of tissue (biopsy) - People whose...
NCT05791448 · University of Southern California Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have a confirmed advanced solid tumour (diagnosed through a tissue or cell sample) that has stopped responding to standard treatments, or where no standard treatments exist — in some cases, a doctor may enrol a patient who has chosen to d...
NCT05794971 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older, of any race or sex, whose colorectal cancer has spread to the liver, confirmed by biopsy or imaging - People whose cancer has continued to grow or spread after trying two different standard chemotherapy treatments - People who have at least one liver...
NCT05797077 · Sixth Affiliated Hospital, Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years, of any gender - People who have colorectal cancer that has spread to the liver and have had surgery to fully remove the affected tissue (or had a procedure called ablation with a similar result), based on a specialist team review - People whose blo...
NCT05797805 · Iterion Therapeutics Phase 2 · 2 countries
**Who might be able to join this trial:** - Adults aged 18 or older, of any gender. - People with a confirmed diagnosis of liver cancer (hepatocellular carcinoma, or HCC), either confirmed by a tissue or cell sample from a laboratory report, or diagnosed by a specialist using recognised clinical guidelines. - People w...
NCT05803928 · Hua Li Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma), confirmed by tissue testing or clinical assessment - People whose liver cancer came back within 3 years after surgery or ablation treatment to...
NCT05810402 · University Hospital, Montpellier Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma, or HCC) and whose medical team has recommended a specific type of immunotherapy (called PD-1 or PD-L1 treatment) as their first treatment - People wh...
NCT05828446 · Naik Vietti Violi Not Applicable · 1 country
**Who might be able to join this trial:** - Adults who have a chronic liver disease and who meet the European liver disease guidelines for regular liver cancer screening. - People who have signed an informed consent form agreeing to take part in the study. **Who may not be able to join:** - People who have previously...
NCT05842174 · VA Office of Research and Development Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older (male or female) who have been diagnosed with a specific stage of liver cancer (called BCLC Stage B hepatocellular carcinoma) and have been referred for a procedure called TACE - People whose liver tumour measures at least 3 cm across and has been confirme...
NCT05844046 · Enrico De Toni Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older at the time of joining the study - People who have been diagnosed with liver cancer (HCC) confirmed by a laboratory examination of tumor tissue - People who have not previously received any systemic (whole-body) treatment for their liver cancer - People wh...
NCT05861505 · Amsterdam UMC, location VUmc Phase 3 · 1 country
**Who might be able to join this trial:** - People who are over 18 years of age - People who are in generally good health and able to carry out daily activities (as assessed by their doctor using standard health scales) - People who have a confirmed diagnosis of colorectal cancer based on tissue testing - People who ha...
NCT05863195 · ECOG-ACRIN Cancer Research Group Phase 3 · 1 country
Who might be able to join this trial: - People aged 18 or older. - People diagnosed with colorectal cancer that has spread only to the liver and cannot be surgically removed. - People whose cancer has not visibly spread outside the liver (though small, stable lung nodules under 6mm may be acceptable — confirm with tria...
NCT05866783 · University Hospital, Ghent Not Applicable · 1 country
**Who might be able to join this trial:** - You have signed and dated a consent form agreeing to take part in the study - You have been diagnosed with hepatocellular carcinoma (a type of liver cancer) - You are 18 years of age or older - You are able to attend scheduled appointments and follow the study requirements -...
NCT05871892 · University of Aarhus Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been newly referred to a specialist with a suspected or confirmed diagnosis of liver cancer (hepatocellular carcinoma, or HCC) - People who are 18 years of age or older **Who may not be able to join:** - People who do not wish to take part in the study - Peop...
NCT05882370 · Fei Gao Phase 2 · 1 country
**Who might be able to join this trial:** - People who have agreed to take part and have signed a consent form - People aged 18 to 75 years old (male or female) - People who have been clinically or pathologically diagnosed with hepatocellular carcinoma (a type of liver cancer) and have at least one measurable area of...
NCT05887661 · The First Affiliated Hospital with Nanjing Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been clinically diagnosed with hepatocellular carcinoma (a type of liver cancer) - People for whom laparoscopic hepatectomy (keyhole surgery to remove part of the liver) has been chosen as the surgical approach, and who agree to take part **Who may not be abl...
NCT05911633 · Terumo Europe N.V. Not Applicable · 4 countries
**Who might be able to join this trial:** - You are at least 18 years old - You have been diagnosed with liver cancer (HCC) confirmed by a tissue sample or by standard European liver disease guidelines - Your tumor(s) are smaller than 5 cm, and the total of your largest tumor's size (in cm) plus the number of tumors yo...
NCT05917431 · Peking University Cancer Hospital & Institute Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People whose ability to carry out daily activities is largely unaffected by their illness (confirm with trial site for exact scoring) - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either through imaging or...
NCT05926726 · RenJi Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who are willing to take part and able to sign a consent form - People expected to live for at least 12 weeks - People who are generally well enough to carry out light activity or desk work (a doctor will assess this usin...
NCT05931068 · Academisch Ziekenhuis Maastricht Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who are scheduled to have open liver surgery (removing 3 or more segments of the liver) at the MUMC+ hospital - People who understand Dutch well enough to give consent and follow instructions during the study assessments **Who...
NCT05935189 · Nikomed Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue sample (biopsy) - People who are of Armenian descent - People who have signed a form agreeing to take part in the trial Who may not be able to join: - People who have not...
NCT05937295 · University Hospital Tuebingen Phase 1 · 1 country
**Who might be able to join this trial:** - People who are able to understand and are willing to sign a written consent form to take part in the study. - People who have been diagnosed with fibrolamellar hepatocellular carcinoma (a rare type of liver cancer) or another type of cancer that has spread or cannot be surgi...
NCT05953961 · Ochsner Health System Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) based on specific liver imaging standards used by liver disease specialists. - People whose general physical functioning is rated at a level indicating they are fully active or have only mi...
NCT05954897 · Guangdong Provincial People's Hospital Phase 2 · 1 country
Who might be able to join this trial: - People aged 18 years or older. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) according to recognised international diagnostic guidelines. - People whose liver cancer has been classified as stage C using the Barcelona Clinic Liver Cancer (...
NCT05970666 · The First Affiliated Hospital of Xiamen University Phase 2 · 1 country
**Who might be able to join this trial:** - Adults between 18 and 75 years old, of any gender - People diagnosed with primary liver cancer (hepatocellular carcinoma) either through standard clinical diagnosis guidelines or confirmed by a tissue or cell sample, with at least one measurable tumour - People who have not...
NCT05984511 · Third Affiliated Hospital, Sun Yat-Sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed by imaging, tissue sample, or cell testing - People whose liver cancer has spread into a specific part of a major liver blood vessel, classif...
NCT05985798 · Second Affiliated Hospital of Guangzhou Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - People diagnosed with advanced liver cancer (BCLC Stage C), confirmed either through a tissue sample or by clinical assessment - People whose liver cancer is suitable for a procedure called TACE (a treatment that delivers chemotherapy directly to the liver through blood vess...
NCT05992220 · Asan Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are between 19 and 80 years of age - People whose liver is functioning at a level doctors classify as "Child-Pugh class A" (a measure of liver health — confirm with trial site) - People whose general physical health and ability to carry out daily activities is rate...
NCT05992584 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that cannot be removed by surgery, at a stage classified as BCLC B or C, confirmed by biopsy or clinical assessment - People who have at least one measurable liver tumour that has not yet been treated - Pe...
NCT05994859 · Second Affiliated Hospital of Guangzhou Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (liver cancer), confirmed either by a tissue sample or by clinical assessment - People who have not received any previous treatment for their liver cancer - People who have at least one measurable liver tumour that...
NCT06005740 · TORL Biotherapeutics, LLC Phase 1 · 2 countries
Who might be able to join this trial: - You have an advanced solid tumor (a cancer that has spread or cannot be removed) - Your cancer can be measured on scans, following standard measurement guidelines called RECIST v1.1 - You are generally able to carry out daily activities with little or no limitation (confirm with...
NCT06007846 · Inova Health Care Services Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People with a new diagnosis of liver cancer (hepatocellular carcinoma) that has not yet been treated, confirmed by tissue sample or imaging, with at least one tumour that can be measured using standard imaging guidelines. A previous liver cancer tr...
NCT06015022 · University of Texas Southwestern Medical Center Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with cirrhosis (scarring of the liver), either through clinical assessment or a tissue biopsy - People who do not currently have any active liver complications (such as fluid buildup, bleeding, or confusion related to...
NCT06018714 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colorectal cancer (specifically adenocarcinoma) that has spread to the liver - People between 18 and 75 years old, of any gender - People who have already received a first course (first-line) of chemotherapy and whose cancer was either red...
NCT06024837 · Centre Hospitalier Universitaire de Saint Etienne Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with colorectal cancer that has spread to the liver and/or the lining of the abdomen (peritoneum) - Your doctors have a plan to perform surgery with the goal of fully removing the cancer Who may not be able to join: - Your colorectal cancer has not spread...
NCT06027086 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with Fibrolamellar Carcinoma (FLC) — a rare type of liver cancer — that has spread to other parts of the body or cannot be removed by surgery. - People whose tumour tissue has tested positive for a specific genetic change called the DNAJB1-PRKA...
NCT06034977 · Chang Gung Memorial Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed by imaging scans, tissue sample, or cell sample. - People who meet specific genetic and/or blood test results — specifically, those with a certain combination of genetic markers (r...
NCT06041477 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old - People with a general health status rated as fully active or restricted only in physically strenuous activity (confirm with trial site) - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) at a specific mid-t...
NCT06044506 · Dr Cipto Mangunkusumo General Hospital Phase 1 · 1 country
**Who might be able to join this trial:** - You are between 20 and 60 years old - You have been diagnosed with liver cancer (Hepatocellular Carcinoma) classified at a moderate to advanced stage (known as BCLC Stage B or C) - You are able to carry out most normal daily activities, as measured by a standard health scorin...
NCT06050200 · Medical University of Warsaw Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have been assessed by their doctor as suitable for liver surgery to remove part of the liver - People where the portion of liver that would remain after surgery is less than 30% of the normal expected liver size for their body...
NCT06050252 · National Cancer Institute (NCI) Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with intrahepatic cholangiocarcinoma (a type of bile duct cancer that starts inside the liver), confirmed by a tissue or cell sample, and whose cancer appears removable by surgery based on imaging scans. - People whose cancer can be measured on...
NCT06060769 · Fifth Affiliated Hospital, Sun Yat-Sen University Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - Your liver must be functioning at a level rated as "A" or "B" on a standard liver health scoring system (called Child-Pugh classification) - You have a long-term (chronic) liver disease and have been identified as being at high risk of devel...
NCT06061276 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been clinically diagnosed with hepatocellular carcinoma (a type of liver cancer). - People aged between 18 and 75 years. - People whose largest tumor measures at least 10 cm, and whose total tumor size is at least 15 cm. - People with intermediate to advanced larg...
NCT06066333 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form agreeing to take part in the trial - People who are 15 years of age or older at the time of signing the consent form - People who have been diagnosed with metastatic adrenocortical carcinoma (ACC) that has spread...
NCT06077591 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - People who have solid tumour cancers that have spread, cannot be surgically removed, or are at an advanced stage, and whose cancer has stopped responding to at least one standard chemotherapy or targeted therapy treatment. - People whose cancer can be accessed for a biopsy (...
NCT06084299 · Zhiyong Huang Phase 1 · 1 country
**Who might be able to join this trial:** - You must be willing to take part and sign a consent form after being fully informed about the study - You must be between 18 and 70 years old - You must have advanced liver cancer that has been confirmed by a tissue sample (biopsy) - You must be generally well enough to carr...
NCT06090656 · Sun Yat-sen University Phase 2 · 1 country
Who might be able to join this trial: - A diagnosis of liver cancer (hepatocellular carcinoma) confirmed by tissue sample or by meeting recognised medical diagnostic guidelines for this type of cancer. - Adults aged 18 or older. - Fully active and able to carry out normal daily activities without any restriction (a spe...
NCT06093022 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not Applicable · 1 country
Who might be able to join this trial: - You are over 18 years old - You have breast cancer that has spread to the liver (confirm with trial site for exact definition) - You have breast cancer that has spread to the liver and also to other parts of the body outside the liver - You have received any type of treatment (th...
NCT06098547 · Azienda Sanitaria Ospedaliera Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been confirmed by tissue testing to have a type of bile duct cancer that started inside the liver (called intrahepatic cholangiocarcinoma, or iCCA) - People who have been newly diagnosed with this type of cancer for the first time - People whose cancer came b...
NCT06109272 · AbbVie Phase 3 · 6 countries
Who might be able to join this trial: - You have been diagnosed with liver cancer (hepatocellular carcinoma) that has spread or cannot be removed by surgery, confirmed by a biopsy, lab test, or by standard medical guidelines if you also have liver scarring (cirrhosis). - Your liver cancer is classified as Stage B or C...
NCT06125769 · Azienda Sanitaria Ospedaliera Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with perihilar cholangiocarcinoma (a type of bile duct cancer near the liver), confirmed through specific tests such as tissue sampling, a blood marker test, or imaging scans showing a blockage that looks cancerous - People whose cancer cannot...
NCT06126419 · McGill University Health Centre/Research Institute of the McGill Unive... Not Applicable · 1 country
Who might be able to join this trial: - You must be over 18 years old - You are being considered for a major surgery to remove part of the liver - You have bowel (colorectal) cancer that has spread to the liver, and that spread can be removed with surgery Who may not be able to join: - You are not able to give your co...
NCT06130280 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with colorectal cancer that has spread to the liver, confirmed by a biopsy and seen on imaging scans - You are reasonably active and able to carry out daily activities (confirm with trial site for specific fitness le...
NCT06133062 · Chang Gung Memorial Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma/HCC) that doctors have determined cannot be treated with surgery or a liver transplant, with tumours meeting specific size limits (no single tumour larger than 15 cm, and the total size of all tumours...
NCT06140134 · Rutgers, The State University of New Jersey Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who have a confirmed diagnosis of locally advanced intrahepatic cholangiocarcinoma (a type of bile duct cancer that starts inside the liver), based on tissue testing - People whose cancer has...
NCT06157060 · Zhujiang Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 75 years old (male or female) - People whose liver cancer has been identified through pre-surgery scans as an early to intermediate stage (BCLC stage 0, A, or B) and is considered suitable for surgery to remove the cancer completely - People with a good...
NCT06166576 · Seoul National University Hospital Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People diagnosed with liver cancer (hepatocellular carcinoma) that is located in only one lobe of the liver, confirmed by tissue sample and/or imaging scans - People who have at least one liver tumour larger than 10 mm that can be measured on a specialis...
NCT06172205 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Phase 3 · 1 country
Who might be able to join this trial: - People aged 18 to 75, of any gender - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma) that is classified as BCLC stage C (an advanced stage) - People whose liver function is rated as Child-Pugh Grade A or B (these are measures of how well the l...
NCT06178198 · Seoul National University Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by tissue sample and/or medical imaging - People who have no more than five liver tumours on imaging scans, where the largest tumour is bigger than 8 cm - People w...
NCT06179602 · Leiden University Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 years or older - People whose case has been reviewed by a team of medical specialists (a multidisciplinary tumour board) who have recommended a liver treatment procedure that uses heat or cold to destroy tumour tissue through the skin - People who are willing and a...
NCT06190665 · Zhongda Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma) at a specific stage range, need a procedure called TACE (where medicine is delivered directly to the tumor through blood vessels), and are not able to have or have chosen not to have surgery, a liver transp...
NCT06191120 · UMC Utrecht Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People with liver metastases (cancer that has spread to the liver) who have been recommended for surgery to remove those metastases by a specialist medical team. - People who have given written consent to participate in the study. - People who have...
NCT06200831 · Oslo University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People aged between 18 and 80 years old. - People who have both bowel cancer (colorectal cancer) and liver metastases (cancer that has spread to the liver) present at the time of assessment. - People whose primary bowel tumour, located in the colon or upper part of the rectum, ca...
NCT06201065 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) based on specific international guidelines used by liver disease specialists. - People who have at least one tumor that can be clearly measured using established liver cancer assessment met...
NCT06204835 · Institute of Automation, Chinese Academy of Sciences Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma). - People who are planned to have surgery to remove part of the liver (hepatectomy). - People whose liver is functioning at a healthy enough level, classified as Child-Pugh A (confirm with trial site). -...
NCT06205472 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (liver cancer) through laboratory testing of tissue removed during surgery, where the surgical margin (the border between the tumour and the healthy tissue removed around it) was less than 1 centimetre wide - Peopl...
NCT06208371 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older. - You have been diagnosed with colorectal cancer (a specific type called adenocarcinoma), confirmed by a tissue sample test. - Scans have shown that the cancer has spread to the liver only, with no confirmed spread to other parts of the body...
NCT06208397 · Shengjing Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with colorectal cancer that has spread to the liver (known as colorectal liver metastases) - People who have had surgery, with tissue samples taken and examined in a laboratory to confirm their diagnosis - People who have no medical reasons preventi...
NCT06212635 · Region Stockholm Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with decompensated liver cirrhosis (a serious stage of liver scarring where the liver is no longer able to function properly). - Adults aged 18 or older. - Healthy adults aged 18 or older (who would take part as a comparison group). **Who may n...
NCT06215651 · Peking Union Medical College Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged over 18 and up to 75 years old, of any gender, who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) either confirmed by tissue testing or by meeting recognised medical diagnostic guidelines. - People whose liver cancer is classified as BCL...
NCT06218420 · Assistance Publique - Hôpitaux de Paris Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years old or older - You are on the waiting list for a liver transplant in France for liver cancer (hepatocellular carcinoma, or HCC), or you are currently being assessed for a transplant under French health authority (Agence de Biomédecine) rules - Your liver can...
NCT06219096 · West China Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old who have liver cancer or other liver tumours and are scheduled for a keyhole (laparoscopic) liver removal surgery that targets a specific section of the liver - People whose liver is functioning at a level rated as Grade A or B on a standard me...
NCT06241326 · The First Affiliated Hospital with Nanjing Medical University Not Applicable · 1 country
Who might be able to join this trial: - You are 18 years of age or older. - You have been diagnosed with liver cancer (hepatocellular carcinoma), either confirmed by a tissue sample (biopsy) or by medical imaging scans. - Your doctor has assessed that you may benefit from a treatment plan that includes immunotherapy co...
NCT06244225 · Union Hospital, Tongji Medical College, Huazhong University of Science... Phase 2 · 1 country
Who might be able to join this trial: - People who have signed a written consent form before any trial-related procedures begin - People whose physical functioning is rated at 0 or 1 on a standard medical scale (meaning fully active or able to carry out light activities) - People who have been confirmed, through tissue...
NCT06248554 · Chen Xiaoping Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue testing, at an early stage (classified as BCLC stage 0 or A) - People whose cancer has not spread outside the liver - People who showed no si...
NCT06248580 · Yaşar Bayındır, MD Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who have tested positive for the hepatitis B surface antigen (a marker of hepatitis B infection) for at least six months - People who are citizens of the Republic of Türkiye Who may not be able to join: - There are no exclusion criteria listed fo...
NCT06251115 · Shanghai General Hospital, Shanghai Jiao Tong University School of Med... Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old (any gender) - People who are willing to take part and are able to sign a consent form on their own - People diagnosed with advanced liver cancer (hepatocellular carcinoma) confirmed by a tissue or cell sample, at a specific advanced stage, who...
NCT06254248 · Assistance Publique - Hôpitaux de Paris Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 to 90 years who received a liver transplant more than 6 months ago - People who have been diagnosed with liver cancer (HCC) that has come back after their transplant, based on specific recognised diagnostic guidelines - People whose liver cancer has come back...
NCT06257030 · University Hospital of Patras Not Applicable · 1 country
**Who might be able to join this trial:** - People who are older than 18 years of age - Both men and women are eligible - People who have tumours that started in the liver or spread to the liver from elsewhere - People whose cancer is mainly located in the liver - People who have at least one tumour measuring more tha...
NCT06260943 · University of Miami Not Applicable · 1 country
**Who might be able to join this trial:** - Patients who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) and are already enrolled in, or eligible for, a specific liver disease registry at the trial site - Adults aged 18 or older who have been diagnosed with this type of liver cancer, confirm...
NCT06261125 · Mian XI Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma), either confirmed by a tissue biopsy or by standard liver disease diagnostic guidelines - People who have cancer that has spread to lymph nodes in the abdomen, confirmed by CT or MRI scan, where the total...
NCT06261814 · john eisenbrey Phase 2 · 1 country
**Who might be able to join this trial:** - People who are scheduled to receive TACE (a procedure that delivers treatment directly to a liver tumour) for a liver tumour - People who are at least 18 years old - People who are in a stable medical condition - Women of childbearing age who have a negative pregnancy test re...
NCT06280105 · Meng Chao Hepatobiliary Hospital of Fujian Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form before enrolling - People aged over 18 years old, of any sex - People who have been diagnosed with intermediate or advanced liver cancer (hepatocellular carcinoma), confirmed by tissue or pathology testing, or people with liver s...
NCT06280313 · Zhiyong Huang Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 75 years of age (inclusive). - People who have not previously received systemic cancer treatment, or who meet the criteria for spleen removal during treatment. - People diagnosed with liver cancer (hepatocellular carcinoma) that cannot be surgically rem...
NCT06280495 · Sun Yat-sen University Phase 3 · 1 country
Who might be able to join this trial: - Adults aged 18 to 75 years old - People who have been diagnosed with colorectal cancer (a type of bowel cancer) confirmed through laboratory testing of tissue samples - People whose cancer has spread to the liver, with no more than 5 spots (lesions) in the liver, confirmed by sca...
NCT06287723 · University Hospital, Montpellier Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with colorectal cancer that has spread to the liver, as confirmed by a specialist medical team - People whose liver metastases (cancer spread to the liver) appeared either at the same time as or after the origina...
NCT06294548 · University of Alabama at Birmingham Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either by a tissue sample or by standard clinical criteria in people with liver scarring (cirrhosis) - People wh...
NCT06300463 · Weill Medical College of Cornell University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colorectal cancer that has spread (metastasized) to the liver - People who are planning to have surgery to remove their liver metastases - People whose tumor has tested negative for a specific genetic marker called MSI-H/dMMR (confirm with...
NCT06307080 · Shanghai General Hospital, Shanghai Jiao Tong University School of Med... Not Applicable · 1 country
Who might be able to join this trial: - People between 18 and 70 years old (any gender). - People who have been newly diagnosed with pancreatic cancer that has spread to the liver, confirmed by a tissue sample (biopsy) or medical assessment, and has not spread to any other organs. - People whose tumours can be seen on...
NCT06307925 · HC Biopharma Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing to take part voluntarily, understand the study procedures, and sign a consent form - Adults aged 18 to 75 years, of any gender - People who have been diagnosed with an advanced solid tumour (confirmed by laboratory testing of tissue or cells) whose can...
NCT06309485 · Zhejiang Haichang Biotech Co., Ltd. Phase 2 · 2 countries
**Who might be able to join this trial:** - People aged 18 or older who are willing to sign a consent form and follow the study requirements. - People with a confirmed diagnosis of liver cancer (hepatocellular carcinoma, or HCC), either through a tissue sample or by standard clinical criteria. - People whose liver can...
NCT06311851 · Pardis Noor Medical Imaging and Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been confirmed to have liver cancer that has spread (metastatic), either through a tissue biopsy or through specific patterns seen on a CT scan or MRI, and for whom surgery is not an option - People who are generally able to carry out daily activities with li...
NCT06311929 · Chen Xiaoping Phase 4 · 1 country
**Who might be able to join this trial:** - You are between 18 and 75 years old - You have not previously received any local or systemic treatment for liver cancer (hepatocellular carcinoma) - Your liver function is within an acceptable range, based on a scoring system called Child-Pugh (score of 7 or below) - You are...
NCT06313190 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma), either confirmed by a tissue sample or by established medical diagnosis guidelines - People who have liver cancer that has come back or is still present after previous treatment, with no spread to b...
NCT06323382 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue sample, by standard liver cancer diagnostic guidelines, or as a recurrence after surgery - People between 18 and 75 years of age - People whose liver cancer is classif...
NCT06326502 · Etnova Therapeutics Corp. Phase 1 · 1 country
**Who might be able to join this trial:** - Adults aged 19 years or older (male or female) - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma) confirmed by imaging, tissue sample, or fluid sample, whose cancer has continued to grow despite standard treatments, or who cannot tolerate...
NCT06327269 · Chang Gung Memorial Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who are able to start a targeted therapy treatment within 1–2 months after receiving a liver transplant. - People whose anti-rejection medication plan includes three specific drugs: a calcineurin inhibitor, mycophenolate mofetil, and sirolimus. - People who are willin...
NCT06333561 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with a specific type of liver cancer (called infiltrative hepatocellular carcinoma, or HCC) confirmed by MRI or CT scan - Your liver is functioning reasonably well, rated as Child-Pugh class A or B (confirm with trial site), and you are generally able...
NCT06339424 · Chang Gung Memorial Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has been assessed as not suitable for surgery or a liver transplant, with one or more tumours where no single tumour is larger than 15 cm and the total size of all tumours combined is less th...
NCT06341270 · West China Hospital Not Applicable · 1 country
Who might be able to join this trial: - Adults between 18 and 80 years old - People rated as generally healthy to moderately unwell before surgery, based on a standard medical fitness scale (ASA Class I–III) - People who are scheduled for a planned (non-emergency) liver removal surgery Who may not be able to join: - P...
NCT06342414 · City of Hope Medical Center Not Applicable · 2 countries
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of primary liver cancer) confirmed by a tissue sample analysis - People who have been diagnosed with intrahepatic cholangiocarcinoma (a type of bile duct cancer that starts inside the liver) confirmed by a tissu...
NCT06342440 · City of Hope Medical Center Not Applicable · 5 countries
Who might be able to join this trial: - People who have had a colonoscopy at the same time as their blood sample was taken for the study - People who have gone through the standard tests and procedures used in their area to diagnose and determine the stage of their condition, and who had at least one blood sample taken...
NCT06345508 · Centre hospitalier de l'Université de Montréal (CHUM) Not Applicable · 1 country
**Who might be able to join this trial:** - Adults who are already scheduled as part of their regular medical care to have ultrasound or MRI scans to monitor for liver cancer (HCC), or to have an MRI scan to get a closer look at a nodule (small growth) found on the liver. **Who may not be able to join:** - People who...
NCT06349317 · Yongyi Zeng Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent and are able to attend scheduled visits and follow study procedures - People aged 18 to 75 years, of any gender - People diagnosed with liver cancer (hepatocellular carcinoma, or HCC) according to Chinese national guidelines or confirmed...
NCT06349980 · Shanghai Henlius Biotech Phase 2 · 1 country
Who might be able to join this trial: - People who are willing to take part in clinical research, who fully understand the study, and who are able to sign a consent form and complete all required procedures - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnose...
NCT06353126 · RenJi Hospital Phase 4 · 1 country
**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with liver cancer linked to viral hepatitis or cirrhosis, confirmed through scans (such as CT or MRI) or a tissue sample/biopsy, following specific medical guidelines - Your liver function has been rated as reason...
NCT06355895 · University of Pittsburgh Not Applicable · 1 country
Who might be able to join this trial: - People who have a primary cancer in the upper abdomen (such as pancreatic cancer, bile duct cancer, or liver cancer), or cancer that has spread to the upper abdomen (including the liver, adrenal glands, or nearby lymph nodes), and who are scheduled to receive a type of targeted r...
NCT06356584 · Shandong Cancer Hospital and Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People whose general health and ability to carry out daily activities falls within a certain functional range (rated 0–2 on a standard medical scale) - People who have been diagnosed with colorectal cancer that has spread to the liver, confirmed by laboratory testing of tiss...
NCT06360042 · Peking University Cancer Hospital & Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with liver cancer (hepatocellular carcinoma) that has spread to nearby tissues or other parts of the body, or cannot be removed by surgery - People who have not previously received any systemic (whole-body) drug treatment for their liver cancer. Prior use of...
NCT06363006 · Peking Union Medical College Hospital Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a tissue or cell sample, or whose liver cancer has been diagnosed by clinical criteria set by a major liver disease association (AASLD). - People aged 18 to 75 years old. - People who have a...
NCT06363825 · Fujian Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - You are willing to participate, agree to follow-up visits, and have signed a written consent form - You are between 18 and 80 years old (any gender) - You have been officially diagnosed with hepatocellular carcinoma (a type of liver cancer) and have had a tissue sample (biop...
NCT06371157 · Akeso Phase 3 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma), either confirmed by a tissue sample or based on established medical guidelines - Your cancer has not spread to other parts of the body - Surgery, liver transplant, or ablation treatment are not suitable opt...
NCT06374485 · Lee's Pharmaceutical Limited Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old (inclusive). - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma) that cannot be removed by surgery or has spread, confirmed by tissue sample, cell sample, or imaging, and whose cancer has not responded to stan...
NCT06379256 · Chang Gung Memorial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), including those with more than one tumour — confirmed either by a tissue or cell sample test, or by specific patterns seen on a CT or MRI scan - People aged 18 or older at the time of sign...
NCT06382103 · Shanghai Zhongshan Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have recently received their first-ever diagnosis of hepatocellular carcinoma (a type of primary liver cancer). - People with this type of liver cancer who are planned to have surgery, whether or not they are also receiving treatment beforehand to shrink the cancer. -...
NCT06383520 · Union Hospital, Tongji Medical College, Huazhong University of Science... Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing to take part and who, or whose legal representative, can sign a consent form agreeing to participate - Adults aged 18 or older, of any gender - People who have been newly diagnosed with liver cancer (hepatocellular carcinoma), either with strong clinica...
NCT06389422 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that also involves a blood clot in the portal vein or hepatic vein - People aged between 18 and 90 years old - People whose liver measurements meet specific volume and radiation dose thresholds set b...
NCT06397222 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with liver cancer (hepatocellular carcinoma) that cannot be removed by surgery, at a moderate or advanced stage, confirmed either by a biopsy or by clinical assessment - People who have at least one measurable liver tumor that has not yet been treated - Peop...
NCT06397235 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (liver cancer), either confirmed by a tissue sample or diagnosed by their doctor using clinical methods. - People who have at least one measurable liver tumour that can be tracked during the trial. - People whose l...
NCT06398028 · Hospital Universitari Vall d'Hebron Research Institute Phase 4 · 1 country
Who might be able to join this trial: - People who have liver tumors and have been assessed by a hospital's specialist liver tumor team as being suitable for minimally invasive (keyhole) surgery - People who have had a contrast-enhanced MRI scan of the liver within 6 weeks before their planned liver surgery - People wh...
NCT06405321 · Guangxi Medical University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either confirmed by a tissue sample or by clinical assessment. - People who received certain treatments before surgery as their first treatment, such as chemotherapy delivered directly to the l...
NCT06406634 · Hunan Cancer Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form before taking part in the trial - People who have been confirmed to have hepatocellular carcinoma (a type of liver cancer) through a tissue or cell sample, or who meet established medical diagnostic guidelines for this condition...
NCT06418165 · Medical University of Vienna Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 years or older who are undergoing a liver transplant where the donor liver is kept viable using a special cooling and oxygen machine process (called hypothermic oxygenated machine perfusion). Who may not be able to join: - People who are pregnant. - People receivi...
NCT06418659 · Shanghai Changzheng Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - Adults aged 18 years or older, of any gender - People who have a confirmed diagnosis of hepatocellular carcinoma (liver cancer), confirmed using recognised medical guidelines - People whose liver cancer cannot be removed by surgery - People whose liver cancer has gotten wors...
NCT06420440 · Chen Xiaoping Phase 2 · 1 country
**Who might be able to join this trial:** - You are between 18 and 75 years old - You have not previously received any treatment (local or systemic) for liver cancer - Your liver function is at an acceptable level, based on a scoring system called Child-Pugh (score of 7 or below — confirm with trial site) - You are abl...
NCT06426992 · Seoul National University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have liver function that is rated as "A" or "B" on a standard medical scale (called Child-Pugh Class A or B), meaning your liver is still functioning reasonably well. - You have a suspected liver cancer (either primary liver cancer or cancer that has spread to the liver f...
NCT06430983 · Nanjing Medical University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma) or a different type of liver cancer that is not hepatocellular carcinoma. - People who are able to read, understand, and sign a consent form, or who have a legal representative who can do this on...
NCT06434480 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who are generally well enough to carry out daily activities with little or no limitation (as measured by a standard medical scale called ECOG, scoring 0 or 1) - People who have a confirmed diagnosis of hepatocellular carcinoma (a type of liver can...
NCT06446154 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that cannot be removed by surgery, has spread locally, or has spread to other parts of the body — with the diagnosis confirmed by biopsy, cell testing, or specific med...
NCT06449937 · Anhui Provincial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 80 years of age. - People who are willing to participate, have signed a consent form, and are able to attend follow-up appointments. - People whose primary colorectal cancer (bowel cancer) can be fully removed by surgery, and where the diagnosis has bee...
NCT06454578 · Qilu Hospital of Shandong University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part voluntarily and sign a consent form. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) either through a tissue/cell sample test or according to recognised clinical guidelines (2024 Edition). - People w...
NCT06461624 · Zhejiang University Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 70 years, of any gender - People who have voluntarily agreed to take part and signed a consent form (either themselves or through a guardian) - People with liver cancer (HCC) that cannot be surgically removed, classified as stage B or C under a system calle...
NCT06467799 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - You have been newly diagnosed with liver cancer (hepatocellular carcinoma) and have not yet received any treatment for it - Your tumor is considered larger than usual guidelines allow for standard treatment — either one tumor larger than 5 cm, or 2–3 tumors where the largest...
NCT06475118 · CHU de Reims Not Applicable · 1 country
Who might be able to join this trial: - You have recently been diagnosed with a type of liver cancer called hepatocellular carcinoma (HCC), confirmed by imaging scans and/or a tissue sample, following standard diagnostic guidelines - You have had a specific type of abdominal scan (a three-phase contrast-enhanced CT sca...
NCT06478108 · Second Affiliated Hospital of Guangzhou Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - A laboratory test (tissue or cell sample) must have confirmed a cancer diagnosis. - Participants must be 18 years or older and have an estimated life expectancy of more than 3 months. - Liver function must fall within a specific range, measured by a scoring system called Chi...
NCT06478719 · Febico Biomedical Corp. Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years of any gender - People who are willing and able to give written consent to participate - People who have a confirmed diagnosis of liver cancer (hepatocellular carcinoma), confirmed by imaging, tissue sample, or cell sample - People who are willing...
NCT06478927 · Henan Cancer Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old - People whose general health and ability to carry out daily activities falls within an acceptable range for this trial (confirm with trial site) - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma) that cannot...
NCT06482801 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - A laboratory test (tissue or cell sample) has confirmed a cancer diagnosis. - The person is willing and able to sign a consent form before joining the trial. - The person is aged 18 or older and is expected to live for more than 3 months. - Liver function falls within an acc...
NCT06486454 · HistoSonics, Inc. Not Applicable · 1 country
Who might be able to join this trial: - People who are 22 years of age or older - People who have signed the ethics committee or review board approved consent form before any study-related tests or procedures, and who are willing to follow the study procedures and required check-ups - People whose liver tumor or tumors...
NCT06487559 · AbbVie Phase 1 · 1 country
**Who might be able to join this trial:** - You have liver cancer (hepatocellular carcinoma, or HCC) that has spread to nearby tissues, other parts of the body, or cannot be removed with surgery - Your liver is still functioning reasonably well (a measure called Child-Pugh A — confirm with trial site) - Your liver can...
NCT06487663 · Tianjin Medical University Cancer Institute and Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have a confirmed diagnosis of hepatocellular carcinoma (a type of liver cancer), confirmed either through a tissue sample or through standard clinical assessment - People who are willing and able to sign a consent form agreeing to take part in the trial - People w...
NCT06490757 · Assistance Publique - Hôpitaux de Paris Phase 2 · 1 country
**Who might be able to join this trial:** - People who are women, or men whose liver adenoma has been determined to be non-removable by surgery regardless of its size - People who are willing to provide written consent to take part in the study - People who have a liver adenoma (hepatocellular adenoma) confirmed by ti...
NCT06492395 · Second Affiliated Hospital of Guangzhou Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - People who have a confirmed diagnosis of hepatocellular carcinoma (liver cancer) - People whose largest liver tumour is bigger than 7 cm - People whose scans show a blood clot or tumour growth in the main vein supplying the liver (called portal vein tumour thrombus) - People...
NCT06492408 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that has been confirmed by a tissue or cell sample, and who have not yet received any treatment for it. A biopsy before treatment starts may not be needed if one has already been done, but diagnosis...
NCT06498622 · Anhui Provincial Hospital Phase 2 · 1 country
Who might be able to join this trial: - People aged 18 to 80 years old, of any gender. - People who are willing to take part voluntarily, have signed a consent form, and are able to attend follow-up appointments. - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma) confirmed by tissue t...
NCT06501482 · Assistance Publique - Hôpitaux de Paris Phase 3 · 1 country
**Who might be able to join this trial:** - Your colorectal cancer spread to the liver (liver metastases) and was surgically removed with the goal of curing you, but you could not receive a specific chemotherapy drug called oxaliplatin before or around the time of surgery, either for medical reasons or because you cou...
NCT06515314 · Shanghai Ruiliyuan Biotechnology Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - You are willing to read and sign a consent form agreeing to take part in the study. - You are between 18 and 75 years old. - You have a specific genetic marker called HLA-A 02:03 (this would be confirmed through a blood test). - You have been diagnosed with liver cancer (hep...
NCT06523608 · University Hospital Muenster Not Applicable · 1 country
**Who might be able to join this trial:** - People who are admitted to hospital or attending as an outpatient with advanced chronic liver disease, diagnosed based on a standard set of medical guidelines called the BAVENO criteria **Who may not be able to join:** - People who are pregnant - People who are under 18 year...
NCT06524557 · Xijing Hospital Not Applicable · 1 country
Who might be able to join this trial: - People between 18 and 70 years of age - People who have had a liver examination performed before an ultrasound-guided liver biopsy or surgery - People whose liver tumor can be seen clearly on a standard ultrasound scan - People whose largest tumor image has been saved in a specif...
NCT06526104 · The University of Texas Health Science Center at San Antonio Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with liver cancer (hepatocellular carcinoma/HCC) confirmed either by biopsy or by CT or MRI scan, at a stage where the cancer is either advanced (BCLC stage C) or at an intermediate stage (BCLC stage B) where local treatments are not suitable - People who ha...
NCT06526338 · Robert C. Martin Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing the consent form. - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed either by imaging scans using standard criteria or by a tissue biopsy. - Your treatment plan includes a procedu...
NCT06530251 · Akeso Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent to participate. - People who have a life expectancy of at least 3 months. - People who are generally well enough to carry out daily activities with little or no limitation (as measured by a standard medical scale called...
NCT06537193 · Asan Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have had curative treatment (surgery or local ablation) for liver cancer (HCC) and have had no recurrence for more than two years after that treatment - People who have never received systemic treatment, radiation therapy, or a procedure called trans-arterial chemoembo...
NCT06542796 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
Who might be able to join this trial: - People diagnosed with advanced liver cancer (hepatocellular carcinoma) Who may not be able to join: - People who have serious ongoing health conditions such as severe diabetes, heart failure, or liver and/or kidney failure - People who have a history of schizophrenia - People wh...
NCT06544083 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing to give their voluntary written consent to participate - People aged 18 years or older but under 75 years old, of any gender - People who have been diagnosed with, or are suspected of having, liver cancer for the first time within the past 42 days befo...
NCT06545630 · West China Hospital Phase 1 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with colorectal cancer confirmed by a laboratory test (biopsy or tissue sample) - You are generally able to carry out normal daily activities with little or no restriction (confirm with trial site) - Your tumor has been tested and shown to have a speci...
NCT06550921 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with primary (first-occurring) liver cancer (HCC), confirmed by biopsy or by standard clinical guidelines - People whose liver cancer has spread to a small number of sites (called oligometastasis), with the spread detected within three months o...
NCT06551272 · Center Eugene Marquis Phase 2 · 1 country
**Who might be able to join this trial:** - You are a man or woman aged 18 or older - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed by a biopsy or scan using recognised medical guidelines - Your liver cancer has spread, cannot be surgically removed, or is considered advanced,...
NCT06555003 · Tehran University of Medical Sciences Phase 3 · 1 country
**Who might be able to join this trial:** - People who have colorectal cancer that has spread to the liver, where the cancer cannot be fully removed by surgery or is on the borderline of being removable. - People who have not yet received chemotherapy for their metastatic (spread) disease. - People who are reasonably w...
NCT06555133 · Brown University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with colorectal cancer (a type of bowel cancer) that has been confirmed by a tissue sample analysis, specifically the type called adenocarcinoma. - People whose cancer has spread to the liver and cannot be removed by surgery, with the liver bei...
NCT06558227 · Suzhou Zelgen Biopharmaceuticals Co.,Ltd Phase 2 · 1 country
Who might be able to join this trial: - People who fully understand the study and are willing to sign a consent form agreeing to take part. - People aged between 18 and 75 years old. - People who are rated as largely able to carry out daily activities with little to no limitation, based on a standard medical assessment...
NCT06559761 · Chinese PLA General Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) based on tissue testing, classified according to World Health Organization standards. - People whose first planned treatment is surgery aimed at fully removing the liver cancer (curative-intent...
NCT06561399 · Fujian Provincial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing to take part and able to sign a consent form agreeing to join the study - People aged between 18 and 75 years old, of any gender - People whose liver is functioning at a level that doctors classify as "Child-Pugh class A" (a measure of how well the liv...
NCT06567353 · Ruijin Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Women between 18 and 75 years of age - People who have been diagnosed through a tissue/cell test (pathology) with breast cancer that has spread to the liver, and who are unable to have surgery or have chosen not to have surgery - People who have no more than 3 liver tumours,...
NCT06571396 · Qilu Hospital of Shandong University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing to take part voluntarily and have signed a consent form. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) either through a tissue/cell test or through clinical guidelines. - People who have already received immuno...
NCT06581315 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who had surgery to fully remove a liver cancer tumour within the 4 weeks before being enrolled in the trial - People whose tumour characteristics show a high risk that the cancer could come back - People who did not receive any cancer treatment before surgery, except...
NCT06590246 · Shanghai AbelZeta Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who voluntarily agree to take part and sign a consent form (or have a legal guardian sign on their behalf) - People aged 18 to 75 years old at the time of signing the consent form - People who have been confirmed by tissue or cell testing to have advanced liver cancer...
NCT06590259 · Shanghai 6th People's Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People between 18 and 75 years of age (any gender) - People who have been diagnosed with colorectal cancer that has spread to the liver, where the liver tumours cannot be surgically removed, or where surgery is not tolerated or has been declined - People whose original bowel...
NCT06590948 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are at high risk of liver cancer, including those with liver cirrhosis, chronic hepatitis B, a current or past diagnosis of liver cancer, or adults who have had a liver transplant or are being monitored after a liver transplant - People who had two specific types...
NCT06593964 · Zhongda Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with liver cancer at a certain stage (Chinese Liver Cancer Staging Scheme, stage IIb–IIIa), or those at an earlier stage (Ia–IIa) whose treating doctor has determined that surgery, transplant, or ablation is not suitable or who do not wish to have those trea...
NCT06595108 · Yonsei University Not Applicable · 1 country
Who might be able to join this trial: - People aged between 19 and 80 years old - People whose liver is functioning at a level that doctors classify as "Child-Pugh class A," meaning the liver is still working reasonably well (confirm with trial site) - People with a physical fitness and activity level that falls within...
NCT06600321 · Alnylam Pharmaceuticals Phase 1 · 3 countries
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed by a biopsy, lab test, or — if you have liver scarring (cirrhosis) — by specific medical guidelines - You have already tried at least one type of systemic treatment (such as drug therapy g...
NCT06601231 · Erasmus Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have cirrhosis (scarring of the liver at its most advanced stage) - People with chronic hepatitis B (without cirrhosis) who have a family history of liver cancer, or who score in the intermediate-to-high risk range on certain liver cancer risk scoring tools used by doc...
NCT06605664 · Chang Gung Memorial Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that cannot be removed with surgery or treated with a liver transplant, and who are planned to receive radiation therapy along with the medicines atezolizumab and bevacizumab. Tumours must me...
NCT06607107 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) — confirmed by tissue sample, cell sample, or clinical assessment — at a stage classified as BCLC A or B that falls outside the Milan criteria (a standard used to assess liver cancer spread...
NCT06607120 · Zhongda Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by imaging scans, tissue sample, or cell testing - People whose liver cancer is classified as an advanced stage (BCLC Stage C), meaning the cancer has spread outside the liver and/or h...
NCT06609850 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People aged between 18 and 75 years old - People who have been diagnosed with recurring liver cancer (cancer that has come back after previous treatment), confirmed by imaging scans - People whose recurring liver cancer is at an intermediate stage, meaning they have either two to...
NCT06609863 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been clinically diagnosed with hepatocellular carcinoma (a type of liver cancer) - People aged between 18 and 75 years - People whose largest tumor measures 10 cm or more - People whose liver cancer is classified as intermediate-advanced stage with a large tumor,...
NCT06609876 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People between 18 and 75 years of age - People whose liver cancer (hepatocellular carcinoma, or HCC) has come back after previous treatment, and this is either the first or second time it has returned - People whose returned cancer meets specific size limits — either one tum...
NCT06620302 · Children's Oncology Group Phase 2 · 1 country
"Who might be able to join this trial: - For Phase 1: People who are at least 1 year old and no older than 21 years old at the time of joining the study. - For Phase 2: People who are at least 1 year old and no older than 39 years old at the time of joining the study. - For Phase 1: People who have a solid tumour that...
NCT06621472 · Cairo University Not Applicable · 1 country
**Who might be able to join this trial:** - People whose overall physical health before surgery is rated as either "ASA II" (mild systemic disease) or "ASA III" (serious systemic disease) — a classification assigned by an anaesthesiologist (confirm with trial site) - People with a Body Mass Index (BMI) between 20 and 3...
NCT06622031 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma), confirmed by a biopsy or by standard clinical diagnostic guidelines - People who have a blood clot or tumour invasion in the main vein supplying the liver (called portal vein tumour thrombus), ra...
NCT06623474 · Nanfang Hospital, Southern Medical University Not Applicable · 1 country
Who might be able to join this trial: - People between 18 and 80 years old who are having surgery to remove part of their liver because of a type of liver cancer called hepatocellular carcinoma. - People who are willing to sign a consent form agreeing to take part in the study. Who may not be able to join: - People wh...
NCT06628661 · Chang Gung Memorial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have a single liver cancer tumour that can be treated with surgery **Who may not be able to join:** - People whose cancer has spread beyond an early stage (specifically, those whose cancer does not fall into the pT1N0M0 or pT2N0M0 categories — confirm with trial s...
NCT06630624 · M.R. Meijerink Phase 2 · 1 country
**Who might be able to join this trial:** **Criteria that apply to all phases:** - People who have colorectal cancer that has spread to other parts of the body, with tumors that can be measured on scans using standard criteria - People whose original bowel tumor has already been surgically removed, or whose original t...
NCT06632093 · First Hospital of China Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed by a scan, tissue sample, or cell sample - Your liver cancer is at an advanced stage (known as BCLC stage C) and has spread into a major blood vessel near the liver (the portal vein) - You...
NCT06632717 · National Taiwan University Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to give signed agreement to take part and follow the study's requirements - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either by tissue sample or by specific liver scan results on CT or MRI - People whose liver...
NCT06638502 · HepaRegeniX GmbH Phase 2 · 5 countries
Who might be able to join this trial: - People who have liver metastases (cancer that has spread to the liver) that originally came from colon cancer, and who are planned to have surgery to remove those metastases with the goal of removing all of the cancer - For Part 1 of the trial only: people who are in a stable con...
NCT06641713 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been clinically diagnosed with primary liver cancer (hepatocellular carcinoma, or HCC) — meaning the cancer started in the liver, not spread there from elsewhere - People aged between 18 and 75 years - People whose largest liver tumour measures 10 cm or more -...
NCT06644430 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma, or HCC), confirmed by a tissue sample or by clinical assessment using recognised liver disease guidelines - People whose liver cancer has spread to the lungs in a limited way (called oligometastas...
NCT06644937 · Zhujiang Hospital Phase 3 · 1 country
Who might be able to join this trial: - People who are willing to take part and have signed a consent form agreeing to participate in the study - Adults aged 18 to 75 years old (male or female) - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue testing - People w...
NCT06652243 · Shanghai General Hospital, Shanghai Jiao Tong University School of Med... Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who are aged 18 to 70 years old, of any gender, and are able to agree in writing to take part and follow the trial schedule - People who have been diagnosed with liver cancer (specifically hepatocellular carcinoma) according to 2024 Chinese guidelines, and whose tumor...
NCT06653062 · Tongji Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) - People whose liver cancer diagnosis was made following recognised international guidelines for liver cancer management - People who have at least one tumour that is large enough to be measured...
NCT06664996 · West China Hospital Phase 2 · 1 country
Who might be able to join this trial: - Adults over 18 years old, of any gender. - People who are willing and able to attend scheduled visits, follow the treatment plan, and complete required tests and procedures, confirmed by signing a consent form. - People who have been diagnosed with liver cancer (hepatocellular ca...
NCT06669377 · Zhongda Hospital Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 years or older - People who have been diagnosed with hepatocellular carcinoma (liver cancer) confirmed by tissue or cell testing, or by recognised clinical features - People whose liver cancer has spread into the main portal vein (the large blood vessel that carrie...
NCT06676982 · Zhejiang University Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 80 years, of any gender - People who are willing to take part voluntarily and are able to sign a consent form themselves, or have a guardian sign on their behalf - People who have been formally diagnosed with hepatocellular carcinoma (liver cancer) at stage...
NCT06681818 · Englewood Hospital and Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who are planning to have surgery to remove part of their liver, either due to a primary liver condition or cancer that has spread to the liver - People who are able to understand and are willing to sign a consent form agreeing to take part Who may not be able to join: - P...
NCT06687941 · Aptamer Sciences, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - You are male or female and are 19 years old or older - You have been diagnosed with an advanced or returning solid tumor cancer, confirmed by laboratory testing of tissue or cell samples - Your tumor tests positive for a protein called GPC3, confirmed by a special lab test (c...
NCT06689540 · Shen Lin Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a tissue or cell sample, but not the fibrolamellar, sarcomatoid, or mixed liver-bile duct cancer types - People whose liver cancer tumour tests positive for a protein called GPC3, detect...
NCT06689670 · inTumo Therapeutics, Inc. Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with primary or secondary liver cancer (cancer that started in the liver, or cancer that has spread to the liver from elsewhere). - People whose overall health and activity level falls within a moderate range — specifically, an ECOG Performance...
NCT06690528 · Azienda Ospedaliera di Padova Phase 2 · 1 country
**Who might be able to join this trial:** - Adults who were between 18 and 75 years old when they were diagnosed - People who have been confirmed by laboratory testing (from a tissue or cell sample) to have pancreatic adenocarcinoma (a specific type of pancreatic cancer) that was considered removable by surgery or bor...
NCT06694636 · Zhongda Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either based on clinical assessment or confirmed by a tissue sample. - People whose liver cancer has spread to other parts of the body or has grown in ways that make surgical removal not possib...
NCT06695026 · Rznomics, Inc. Phase 2 · 1 country
Who might be able to join this trial: - Adults of any gender may be considered for this trial - People who have been diagnosed with liver cancer (hepatocellular carcinoma) at a specific stage of progression known as BCLC stage B or C - People whose cancer cells test positive for a specific protein marker called hTERT,...
NCT06698146 · Northwestern University Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older of any gender who are listed as liver transplant candidates at Northwestern and have liver metastases (cancer that has spread to the liver) from colorectal cancer. - People who are able to provide their own informed consent, without needing a legal rep...
NCT06698250 · Anwaar Saeed Phase 2 · 1 country
**Who might be able to join this trial:** - People who have liver cancer (hepatocellular carcinoma) that cannot be removed by surgery. - People who have not yet received any systemic (whole-body) treatment for their unresectable liver cancer. - People aged 18 or older who are in reasonably good general health and able...
NCT06710223 · University of California, San Diego Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form before any study procedures begin - People aged 18 years or older - People who have been diagnosed with locally advanced, metastatic, or inoperable liver cancer (hepatocellular carcinoma), confirmed either by tis...
NCT06711211 · Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) Not Applicable · 1 country
Who might be able to join this trial: - You are 18 years old or older and have been diagnosed with one of the following cancers: oesophageal cancer, stomach cancer, pancreatic cancer, liver cancer, gallbladder or bile duct cancer, small intestine cancer, appendix cancer, gastrointestinal stromal tumour, colorectal canc...
NCT06717919 · Philipp Dutkowski Phase 4 · 17 countries
**Who might be able to join this trial:** - Adults (over 18 years old) who are listed to receive a liver transplant and have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed by a specific scan result or a tissue biopsy - People whose liver cancer meets a size and number rule called the...
NCT06718153 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 years or older - People who have had surgery to remove a liver cancer (hepatocellular carcinoma, or HCC) - People for whom next-generation sequencing (a type of detailed genetic testing) data is available from their cancer tissue - People for whom preserved tissue...
NCT06718530 · Centro di Riferimento Oncologico - Aviano Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 or older who have a long-term (chronic) hepatitis C infection, liver scarring (fibrosis), severe liver scarring (cirrhosis), or liver cancer linked to hepatitis C - People who are able to understand and are willing to sign a consent form agreeing to take part in th...
NCT06725121 · University Health Network, Toronto Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged between 18 and 70 years old - People weighing more than 30 kg - People whose liver function falls within a specific range, known as Child-Pugh score A5 to B7 (confirm with trial site) - People who have large blood vessel involvement from their liver cancer, class...
NCT06726161 · RayzeBio, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People who have a confirmed diagnosis of liver cancer (HCC) through a tissue or cell sample test - People whose liver cancer is classified as BCLC Stage C, or BCLC Stage B that cannot be treated with local tum...
NCT06737913 · Sun Yat-sen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part and have signed a consent form agreeing to join the study - People aged 18 or older at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) through clinical assessment...
NCT06740370 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma, or HCC) confirmed either by biopsy or by standard clinical imaging guidelines - People whose CT scan shows that bleeding from the tumor has stopped (hemostasis is present) - People whose tumo...
NCT06742424 · West China Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either confirmed through a tissue sample or through standard clinical diagnosis methods - People whose liver cancer has spread outside the liver (metastases) and cannot be removed with surgery,...
NCT06742892 · Shanghai Henlius Biotech Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part in clinical research, who fully understand the study, and who are able to sign a consent form and complete all required procedures - People aged 18 to 75 years old (any gender) - People who have been diagnosed with hepatocellular carcinoma...
NCT06745895 · H. Lee Moffitt Cancer Center and Research Institute Not Applicable · 1 country
**Who might be able to join this trial:** - You receive your healthcare at one of the clinics taking part in this study. - You are between 45 and 75 years old. - You are not up to date with colorectal cancer (bowel cancer) screening — for example, you have not had a colonoscopy in the last 10 years or a stool blood te...
NCT06746194 · Ruijin Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with advanced hepatocellular carcinoma (liver cancer) that cannot be removed by surgery. - People who have signed and dated a consent form agreeing to take part in the trial. - People who are willing and able to follow all the study procedures t...
NCT06753136 · Istituto Oncologico Veneto IRCCS Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who are able to understand the proposed treatment and who agree to take part by signing a consent form - People who have been diagnosed with cancer that has spread to internal organs (either as a primary location or spread from elsewhere), of any...
NCT06753903 · IRCCS San Raffaele Not Applicable · 1 country
**Who might be able to join this trial:** - You are over 18 years old - You have a suspected colon or colorectal cancer that has **not** yet been confirmed by a biopsy - You have had a CT scan performed on a specific type of scanner called a Photon-Counting Detector CT (PCD-CT) (confirm with trial site) - You have had...
NCT06762782 · The First Affiliated Hospital with Nanjing Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 80 years old, of any gender - People who had surgery to fully remove liver cancer between 4 and 8 weeks before joining the trial, where the surgery met specific requirements: no visible tumour spread into major blood vessels, bile ducts, or nearby...
NCT06764316 · Bayer Phase 1 · 8 countries
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma) that has spread or cannot be surgically removed, confirmed by a biopsy or scan, or by specific liver disease guidelines if you also have cirrhosis. - A test on your tumor tissue has shown a positive result...
NCT06766643 · Tianjin Medical University Cancer Institute and Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed written consent before any trial procedures begin - People aged 18 to 75 years - People whose liver disease severity and overall physical function fall within acceptable ranges, as measured by the Child-Pugh score (≤7) and Karnofsky Performance Scale s...
NCT06767579 · Yonsei University Not Applicable · 1 country
Who might be able to join this trial: - Adults who are 19 years of age or older - People who are having a liver transplant and are planned to receive either sevoflurane (a gas used to keep patients asleep during surgery) or propofol (an intravenous medication used to keep patients asleep during surgery) as their anesth...
NCT06774690 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a type of liver cancer called hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (iCCA) - People whose doctors have recommended, or who have already received, one of these liver cancer treatments: trans-arterial embolization (TAE...
NCT06777017 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with chronic (long-term) liver disease, confirmed through medical tests and imaging. - People whose liver cancer (hepatocellular carcinoma, or HCC) has been assessed as suitable for a heat-based treatment called radiofrequency ablation (RFA), based...
NCT06777485 · Anhui Provincial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older, of any gender - People who have been diagnosed with one of the following liver cancers — hepatocellular carcinoma, intrahepatic cholangiocarcinoma, mixed hepatocellular-cholangiocarcinoma, or metastatic hepatocellular carcinoma — either through imagi...
NCT06777628 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) - People whose lab tests, treatments, and follow-up care are carried out at the trial centre - People who have given written consent to take part in the study Wh...
NCT06777914 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed (by imaging or tissue sample) with a primary liver or bile duct cancer (such as hepatocellular carcinoma, cholangiocarcinoma, or a combined type) that occurred either without a known underlying chronic liver disease, or alongside a liver disease with...
NCT06778317 · Central Hospital, Nancy, France Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 years or older. - People who have been diagnosed with cirrhosis (scarring of the liver), confirmed through clinical assessment, blood tests, imaging, or a liver biopsy. - People whose cirrhosis is linked to one or more of the following causes: alcohol use, hepa...
NCT06781242 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with PFIC (Progressive Familial Intrahepatic Cholestasis), CCLDs (Childhood Cholestatic Liver Diseases), or HBCs (Hereditary Biliary Conditions) (confirm with trial site for exact diagnoses covered) - Pe...
NCT06787183 · Fujian Cancer Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years, of any gender - People who have been diagnosed with rectal cancer that has spread to the liver (stage M1), confirmed by a pathology test - People whose general health and ability to carry out daily activities meets a minimum threshold score (calle...
NCT06787625 · Regina Elena Cancer Institute Not Applicable · 1 country
Who might be able to join this trial: - People who are over 18 years old - People who have been diagnosed with colorectal cancer (confirmed through tissue or cell testing) that has spread to the liver - People whose medical team has identified them as suitable candidates for surgery to treat colorectal cancer that has...
NCT06788002 · Hunan Cancer Hospital Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 to 70 years, who are male or not currently pregnant - People whose cancer has been confirmed by a tissue biopsy as a specific type of nasopharyngeal (back-of-the-nose/throat) cancer classified as WHO Type II or III - People whose cancer is classified as Stage IVB...
NCT06789757 · Inova Health Care Services Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People who have been newly diagnosed with liver cancer (hepatocellular carcinoma) that has been confirmed by biopsy or imaging, and who have not yet received any treatment for it. At least one measurable tumour must be present. A previous liver can...
NCT06789848 · University of Texas Southwestern Medical Center Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with either hepatocellular carcinoma (a type of liver cancer) or biliary tract cancer (cancer of the bile ducts or gallbladder), confirmed through a tissue sample or by accepted medical diagnostic standards. - People whose cancer has spread or cann...
NCT06794073 · Shanghai Zhongshan Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 80 years, of any gender - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either through clinical assessment or tissue testing - People whose liver cancer has been classified at a specific advanced stage (CNLC IIb–IIIa...
NCT06794086 · Jun Huang Phase 3 · 1 country
Who might be able to join this trial: - People who are willing and able to sign and date a written consent form before any study-related procedures begin. - People who have a specific type of colorectal cancer (bowel cancer) that is classified as pMMR/MSS — a subtype identified through laboratory testing. - People aged...
NCT06795022 · AstraZeneca Phase 2 · 7 countries
**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form. - People whose tumour tests positive for a protein called GPC3, confirmed by a central laboratory. People who have previously had treatment targeting GPC3 must have new tumour tissue tested after that prior tre...
NCT06806579 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People who have liver cancer (hepatocellular carcinoma) that cannot be treated with local procedures targeting the tumour directly - People whose doctors have identified them as candidates for a first-line (initial) systemic treatment using atezolizumab-bevacizumab or other immun...
NCT06812039 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People who give voluntary written consent to participate - People aged 18 to 75 years, of any gender - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has not been treated before — either confirmed through a tissue sample or diagnos...
NCT06813508 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with a liver condition called MASLD (a type of metabolic liver disease caused by fat buildup), confirmed using the latest medical guidelines - You are 18 years old or older - If a liver biopsy (a small tissue sample taken from the liver) is needed for your...
NCT06821958 · Charite University, Berlin, Germany Not Applicable · 1 country
**Who might be able to join this trial:** - People who are being treated with a combination of two specific types of immunotherapy drugs that target PD-L1 and CTLA-4 - People who are 18 years of age or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by laboratory...
NCT06828380 · National Cancer Center, Korea Phase 2 · 1 country
Who might be able to join this trial: - People who have signed a consent form to participate in the study - People aged 19 or older at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) based on standard Korean medical guidelines, either through...
NCT06829290 · Universitatsmedizin Mainz - 1. Medizinische Klinik Not Applicable · 1 country
Who might be able to join this trial: - People who have a cancer diagnosis related to the gastrointestinal system (such as cancers of the stomach, bowel, or other digestive organs) - People who have been diagnosed with liver cirrhosis (scarring of the liver) - People who are currently receiving care in an intensive car...
NCT06841172 · Shandong Cancer Hospital and Institute Phase 3 · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma), confirmed either through a tissue sample or by established medical guidelines. - People whose liver cancer was classified as BCLC stage C when their first round of systemic (whole-body) treatment...
NCT06844357 · Zhejiang Raygene Pharmaceuticals Co., Ltd Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma) using a specific set of recognised diagnostic guidelines. - People whose cancer has not spread outside the liver, has not affected nearby lymph nodes, and has no blood vessel involvement from...
NCT06848465 · Daping Hospital and the Research Institute of Surgery of the Third Mil... Phase 1 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old. - People whose colon or rectal cancer has been confirmed by tissue testing to be a specific type called MSS/pMMR adenocarcinoma. - People with rectal cancer where scans (MRI, CT, or rectal ultrasound) show the cancer has reached certa...
NCT06848842 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People who have been diagnosed with colorectal cancer (a type of bowel cancer) confirmed by a tissue sample (biopsy). - People whose cancer has spread to the liver only, as confirmed by scans. Small spots outside the liver (1 cm or smaller) that have no...
NCT06849180 · Zhongda Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with combined hepatocellular-cholangiocarcinoma (a type of liver cancer) confirmed by a tissue or cell sample test - People with this cancer that cannot be surgically removed or has spread, who have already received at least on...
NCT06852820 · Melissa Lumish Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has spread or cannot be surgically removed, confirmed through tissue testing or imaging. - People who have already received one prior treatment for their advanced liver cancer, which m...
NCT06856837 · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Phase 2 · 2 countries
**Who might be able to join this trial:** - People who have signed an informed consent form agreeing to participate. - People who are 18 years of age or older at the time of giving consent. - People who have been diagnosed with a specific type of colorectal cancer (cancer of the colon or rectum that has spread to othe...
NCT06857773 · The Netherlands Cancer Institute Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with colorectal cancer that has been confirmed by a tissue sample (biopsy) - People whose colorectal cancer has spread to the liver in a way that cannot be surgically removed (based on a CT scan done within 4 weeks bef...
NCT06860490 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older. - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) confirmed by imaging, biopsy, or cell testing, and your cancer is at an advanced stage or a stage where curative or local treatments are not suitable. - You have...
NCT06860815 · City of Hope Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to participate (or whose legal representative has done so on their behalf) - People who agree to allow the trial to use stored tissue samples from a previous tumor biopsy (exceptions may be possible with approval from the lead researcher...
NCT06864221 · Nanfang Hospital, Southern Medical University Not Applicable · 1 country
Who might be able to join this trial: - You are willing to take part and have signed a consent form agreeing to join the study. - You are between 18 and 80 years old. - You have been diagnosed with primary liver cancer (cancer that started in the liver) based on current medical guidelines. - Your doctor has decided tha...
NCT06864481 · University Hospital, Montpellier Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People who are willing to take part in the study - People who have cancer and are receiving treatment before surgery (neoadjuvant), after surgery (adjuvant), or as ongoing maintenance treatment - People who are being treated with a type of cancer dr...
NCT06867172 · Carol Davila University of Medicine and Pharmacy Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who have at least one cyst on the pancreas measuring 5mm or larger, identified through CT scan and internal ultrasound, OR people who are healthy with no pancreatic condition, OR people who have been diagnosed with pancreatic cancer confirmed by a...
NCT06870942 · Shanghai Zhongshan Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - A person must have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), either confirmed by a tissue or cell sample, or by liver scarring (cirrhosis) combined with characteristic scan findings. - The liver cancer must have shown limited progression (in 5 or f...
NCT06875128 · Delcath Systems Inc. Phase 2 · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with metastatic breast cancer (cancer that has spread beyond the breast), confirmed by a tissue sample analysis. - People whose breast cancer tests negative for a protein called HER2 (including a type called triple negative breast cancer). - Pe...
NCT06876753 · Zhongda Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (liver cancer) confirmed by a scan, tissue sample, or cell sample - People whose liver cancer is at an advanced stage (BCLC Stage C) and has spread to areas outside the liver - People who have not previously received an...
NCT06877637 · Region Skane Not Applicable · 1 country
Who might be able to join this trial: - People who are over 18 years of age - People who have been clinically diagnosed with a bile duct cancer (either inside the liver, near the liver's main ducts, or further along the duct), gallbladder cancer, or a mixed liver and bile duct cancer, and who are planned to have surger...
NCT06880523 · Canadian Cancer Trials Group Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older with a body weight above 30 kg. - People with a life expectancy of at least 12 weeks. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either by tissue biopsy or by standard clinical criteria in people...
NCT06885879 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People with a confirmed diagnosis of hepatocellular carcinoma (a type of liver cancer) - People whose liver cancer tumour measures at least 3cm in size - People who are planned to receive a specialised form of targeted radiation treatment called St...
NCT06888063 · Erasmus Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years old or older - You are generally in good health and able to carry out daily activities with little or no limitation (confirm with trial site) - Imaging scans show a liver cancer (specifically intrahepatic cholangiocarcinoma) that can be surgically removed — a...
NCT06891742 · Peking University Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old at the time of signing the consent form - People diagnosed with liver cancer (hepatocellular carcinoma) according to recognised diagnosis guidelines - People whose liver tumour tissue or spread (metastatic) tissue, tested within the past year,...
NCT06893887 · Nanjing Tianyinshan Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People who have been diagnosed with a specific type of liver cancer called hepatocellular carcinoma (confirmed by biopsy or tissue sample, or by meeting standard clinical diagnosis guidelines), where curative treatments such as surger...
NCT06898398 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma, or HCC), either through clinical assessment or confirmed by tissue testing - People whose liver tumor measures more than 10 cm across on medical imaging taken before joining the trial - People age...
NCT06899854 · Fondazione IRCCS Policlinico San Matteo di Pavia Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with primary liver cancer (specifically hepatocellular carcinoma or intrahepatic cholangiocarcinoma). - People who are willing and able to sign a consent form agreeing to take part in the trial. - People whose doctor has determined they are ready to...
NCT06902389 · Eastern Hepatobiliary Surgery Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People with advanced liver cancer (hepatocellular carcinoma, or HCC) that cannot be treated with surgery or local treatments, and whose cancer has continued to grow or who could not tolerate one or two previous lines of cancer treatment, and who have either a tissue/cell-bas...
NCT06904014 · Lei ZHAO Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form before any trial-related procedures begin. - Adults aged 18 to 70 years (male or female). - People whose general physical functioning is rated at a level where they are fully active, restricted in physically strenuous activity, o...
NCT06904170 · UNICANCER Phase 3 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either by a tissue sample (biopsy) or by imaging scans using accepted medical guidelines - People with a high level of tumour spread in the liver, meaning at least on...
NCT06904183 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have a confirmed diagnosis of hepatocellular carcinoma (a type of liver cancer) - People whose largest liver tumour is bigger than 7 cm - People who have a tumour clot present in the main vein leading to the liver (as seen on medical imaging) - People whose liver...
NCT06904196 · Second Affiliated Hospital of Guangzhou Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), either confirmed by a tissue sample or by clinical assessment - Your liver cancer has stopped responding to a procedure called TACE (a treatment that delivers medicine directly to liver tumours thr...
NCT06905262 · National Cancer Institute, Naples Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with primary liver cancer (HCC) or another type of cancer, confirmed by a tissue diagnosis from an approved medical facility - People aged 18 years or older (for those with a cancer diagnosis) - People who are able to sign a consent form agreei...
NCT06909708 · Zhongda Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are generally well enough to carry out daily activities with little or no limitation (a standard measure of physical fitness used in cancer care must be 0 or 1) - People with an expected survival of at least 3 months - People who have been diagnosed with liver cancer (...
NCT06911255 · Yoon Jun Kim Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 19 years or older who are able to give written consent to participate and follow the study requirements - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed either by a tissue sample (biopsy) or by medical imaging scans...
NCT06914635 · Fondazione IRCCS Policlinico San Matteo di Pavia Not Applicable · 1 country
**Who might be able to join this trial:** - Adults who are older than 18 years of age at the time of signing the consent form - People who have a primary liver tumor (a tumor that started in the liver) - People who are willing and able to sign a consent form agreeing to take part in the trial **Who may not be able to...
NCT06915753 · Tyra Biosciences, Inc Phase 1 · 4 countries
Who might be able to join this trial: **All participants (all parts of the trial):** - Adults aged 18 or older - People whose cancer has not significantly reduced their ability to carry out daily activities (as measured by a standard medical scale called ECOG, with a score of 0 or 1) - People whose liver, kidneys, and...
NCT06929845 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not Applicable · 1 country
Who might be able to join this trial: - People who are able to understand and agree to participate in the study on their own behalf - People aged 18 years or older - People who have imaging scans suggesting possible liver cancer (HCC), or who have already been diagnosed with liver cancer and have been recommended for s...
NCT06930573 · The First Affiliated Hospital of Zhengzhou University Phase 4 · 1 country
**Who might be able to join this trial:** - People who have given written consent before any trial-related procedures begin - People aged between 18 and 75 years (male or female) - People who are fully active or have only minor restrictions in physical activity (as measured by a standard performance scale called ECOG,...
NCT06938880 · Suzhou Zelgen Biopharmaceuticals Co.,Ltd Phase 2 · 1 country
Who might be able to join this trial: - People who fully understand the study and are willing to sign a consent form agreeing to take part. - People aged between 18 and 75 years old, with no restriction on gender. - People with advanced solid tumour cancers (confirmed by laboratory testing of tissue or cell samples) wh...
NCT06944483 · Seoul National University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by biopsy and/or imaging scans - Your liver tumor is 5 centimeters or larger - The abnormal blood vessels inside your tumor are 3 millimeters or smaller in size - Your liver function falls into a...
NCT06950814 · West China Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who had surgery to remove part of their liver. - People whose tissue samples, examined in the lab after surgery, confirmed a diagnosis of primary hepatic sarcoma (a rare type of cancer that starts in the liver). Who may not be able to join: - People who received any anti-...
NCT06950827 · West China Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People whose liver tumour is located only in the right side of the liver and has been confirmed as hepatocellular carcinoma (a specific type of liver cancer) through laboratory tissue analysis - People who are scheduled for a planned, non...
NCT06954467 · Shanghai Junshi Bioscience Co., Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part and sign a consent form agreeing to participate. - Adults aged 18 or older, of any gender. - People who have been diagnosed with liver cancer (HCC) confirmed by a tissue or cell sample, or with liver cirrhosis meeting specific liver diseas...
NCT06960863 · Tanta University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with advanced liver cancer (hepatocellular carcinoma), confirmed by two imaging scans or a liver biopsy, and are considered suitable for immunotherapy treatment. - Your liver is still functioning reasonably well — if you have liver scarring (cirrhosis)...
NCT06960954 · Tanta University Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older, of any gender. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), with or without spread into nearby blood vessels, confirmed by two imaging scans, or one imaging scan alongside a raised blood protein marker or...
NCT06961617 · Lion TCR Pte. Ltd. Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed either by a tissue sample or by clinical assessment - People whose liver cancer cannot be treated with surgery or local treatments, or whose cancer has continued to grow after those tre...
NCT06978933 · RenJi Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed either by a tissue or cell sample test, or by meeting recognised medical diagnostic guidelines for this type of cancer - People whose liver cancer has continued to grow or spread after rec...
NCT06979219 · Seoul National University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with a type of liver cancer called hepatocellular carcinoma, confirmed by a tissue sample or by specific imaging scan results - Your liver tumor(s) are 5 cm (about 2 inches) or smaller in size - You have 3 or fewer tu...
NCT06986486 · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with a specific type of bile duct cancer (called unresectable peripheral cholangiocarcinoma) that cannot be surgically removed, is located at least 1 centimeter above the upper edge of the pancreas, and has a tumor no larger than 3 centimeters - The diagnosis...
NCT06986785 · Sichuan Baili Pharmaceutical Co., Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to sign a consent form and follow the study requirements - People of any gender aged 18 to 75 years old - People with a life expectancy of at least 3 months - People diagnosed with advanced liver cancer (hepatocellular carcinoma) confirmed by a tissue...
NCT06990659 · University Hospital, Angers Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People diagnosed with hepatocellular carcinoma (a type of liver cancer) or intrahepatic cholangiocarcinoma (a type of bile duct cancer), confirmed either through standard liver association guidelines or through a tissue biopsy. - People whose cancer has...
NCT06995105 · Zhejiang University Phase 2 · 1 country
Who might be able to join this trial: - People who are aged 18 to 75 years (any gender) and willing to sign a consent form - People whose liver cancer has been diagnosed using the 2018 American Association for the Study of Liver Diseases (AASLD) guidelines, and whose cancer is considered inoperable or has spread, at ce...
NCT06999174 · University Hospital Muenster Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with, or are suspected to have, a type of liver cancer called hepatocellular carcinoma (HCC) - You are already planned to receive one of two types of liver treatment — a procedure that delivers chemotherapy directly t...
NCT06999694 · Chang Gung Memorial Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma/HCC) that has been assessed as not suitable for surgery or a liver transplant, with tumours meeting specific size limits (no single tumour larger than 15 cm, and the total size of all tumours less tha...
NCT06999707 · Chang Gung Memorial Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has been assessed as not suitable for surgery or liver transplant, with tumours confirmed either by tissue biopsy or by specific patterns seen on CT or MRI scans. - People whose liver ca...
NCT06999837 · Nantes University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are willing and able to give written consent to take part - You are 18 years old or older - For Group A: You have liver cancer (HCC) either confirmed by tissue sample or by scan results, and are scheduled for a biopsy; OR for Group B: You have known liver cancer and need...
NCT07001085 · Medical University of Warsaw Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years, of any sex - People with colorectal cancer that has spread to the liver (either at the same time as the original diagnosis or later), where the original bowel tumour has already been fully removed, and who have been assessed as suitable f...
NCT07010198 · Zhongshan People's Hospital, Guangdong, China Not Applicable · 1 country
Who might be able to join this trial: - You are willing to voluntarily sign a consent form to take part in the study. - You are officially registered as a resident of Zhongshan City, Guangdong Province. - You are 35 years old or older. - A recent screening test showed that you carry a marker for Hepatitis B (called HBs...
NCT07010315 · M.D. Anderson Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who are at least 18 years old - People who are patients at the HOPE Clinic - People who can speak and read English or Spanish - For the usability testing part of the trial: people who are able to use and browse websites on their own smartphone or on a study computer Who m...
NCT07010497 · Asan Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and sign a voluntary consent form before any trial procedures begin, and who are willing to attend study visits and follow the study schedule. - People aged 19 or older at the time of signing the consent form. - People who have been diagnose...
NCT07014150 · Peking Union Medical College Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part voluntarily, sign a consent form, follow the study requirements, and attend follow-up visits - People who are at least 18 years old at the time of signing the consent form (any gender) - People who have been diagnosed with liver cancer (he...
NCT07018947 · Fundacion Clinic per a la Recerca Biomédica Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older who have signed a consent form agreeing to take part - People whose liver cancer (HCC) has been confirmed by a tissue sample (biopsy) examined in a lab - People whose liver cancer is considered removable by surgery with the goal of removing all of the...
NCT07019844 · VA Office of Research and Development Not Applicable · 1 country
**Who might be able to join this trial:** - You must be an adult aged 18 or older who receives care through the VA (Veterans Affairs) medical system - You must have been recently diagnosed with liver cancer (called HCC) that is at an intermediate or advanced stage (known as BCLC B or C), and you must not have received...
NCT07036874 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have a known chronic liver disease - People who have been diagnosed with hepatocellular carcinoma (a type of primary liver cancer) — either confirmed by imaging scans or tissue testing — and whose doctors have planned surgery or a local pr...
NCT07039201 · Zhejiang University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have read and understood the possible risks and benefits of the trial and have signed a consent form agreeing to take part. - People aged between 18 and 75 years old (including those aged exactly 18 or 75). - People with advanced liver cancer (hepatocellular carci...
NCT07042919 · Devalingam Mahalingam Phase 2 · 1 country
**Who might be able to join this trial:** - People who have a confirmed diagnosis of hepatocellular carcinoma (liver cancer) that cannot be treated with curative intent. - People whose liver cancer has shown clear signs of growing or spreading during or after at least one prior treatment, or who were unable to tolerat...
NCT07044362 · Case Comprehensive Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - People who have colorectal cancer that has spread to the liver only, or who have a small amount of spread to the lungs in addition to the liver - People who are currently receiving a first course of chemotherapy that includes a drug called 5-FU combined with either oxaliplat...
NCT07052253 · Akeso Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years - People whose liver cancer has been confirmed through a tissue or cell sample, or who meet the accepted medical standards for diagnosing liver cancer without a biopsy - People whose cancer is classified as BCLC stage C, or BCLC stage B where the t...
NCT07053072 · West China Hospital Phase 1 · 1 country
**Who might be able to join this trial:** - Adults aged 18 to 70 years old - People who have liver cancer (hepatocellular carcinoma) that has come back or spread to other parts of the body, and where two rounds of standard treatment have already been tried without success - People who have at least one tumour that is...
NCT07053488 · AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC Phase 2 · 1 country
**Who might be able to join this trial:** - Adults between 16 and 85 years old who have severe liver disease or sudden liver failure and have been assessed as needing a liver transplant. - A donor liver from a deceased donor has been allocated and is available to be used in the study after the gene editing process. -...
NCT07059494 · Icahn School of Medicine at Mount Sinai Phase 4 · 1 country
Who might be able to join this trial: - People aged 18 or older who have signed a consent form and are able to follow the study schedule and requirements - People with a newly diagnosed liver cancer (hepatocellular carcinoma, or HCC) that has been confirmed by a tissue sample (biopsy) - People who can provide a suitabl...
NCT07059936 · Union Hospital, Tongji Medical College, Huazhong University of Science... Not Applicable · 1 country
Who might be able to join this trial: - People who were treated for liver cancer (hepatocellular carcinoma) at Wuhan Union Hospital between July 2025 and July 2026 - People who are older than 18 years of age - People who had at least one CT scan or MRI scan taken before their treatment began - People whose liver cancer...
NCT07064681 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years - People who have liver cancer (hepatocellular carcinoma, or HCC) that doctors have determined can be removed by surgery, and which falls into an early-to-intermediate stage (classified as BCLC A or B) - People who have not yet received any treatme...
NCT07070076 · Li Qiang Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old - People in generally good health, able to carry out normal daily activities with little or no limitation (as measured by a standard health performance scale) - People whose liver cancer falls into one of the following categories based on the Ch...
NCT07075120 · University of Hawaii Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a tissue or cell sample - People whose liver cancer is locally advanced or on the borderline of being surgically removable, meeting at least one of these descriptions: a single tumour la...
NCT07091942 · National Taiwan University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either through a tissue sample or through liver cirrhosis plus characteristic scan findings on CT or MRI. - People whose first treatment for liver cancer (using the drug combination atezol...
NCT07099274 · Tianjin Medical University Cancer Institute and Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who are able to understand the study and are willing to sign a consent form voluntarily - People aged 18 or older, of any gender - People who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed either by tissue testing or through clinical assessment...
NCT07100392 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - You must be at least 18 years old. - You must be willing and able to sign a consent form agreeing to take part. - You have been diagnosed with liver cancer (hepatocellular carcinoma/HCC) that has spread or cannot be removed by surgery, confirmed by a tissue sample or by stan...
NCT07100405 · Fudan University Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with liver cancer (hepatocellular carcinoma) - Your liver cancer is at an advanced stage, or at an intermediate stage that cannot be treated with surgery or other local treatments - At least one area of cancer in your...
NCT07101237 · Peking Union Medical College Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are older than 18 and no older than 70 years of age - Both men and women are eligible - People who have been diagnosed with primary liver cancer (HCC) or bile duct cancer within the liver (ICC) - People who are planned to have surgery to remove the tumour, or treatment...
NCT07105748 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to participate in the study. - People aged 18 or older at the time of joining the study. - People whose cancer cannot be treated with surgery or other local treatments aimed at a cure. - People who have had a biopsy confirming a specific...
NCT07106814 · Anhui Provincial Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - The patient or their legal guardian must be willing to sign a consent form agreeing to take part. - Adults aged over 18 and up to 70 years old, of any gender, may be considered. - People with advanced solid tumours confirmed by laboratory testing of tissue or cell samples, w...
NCT07109440 · Jules Bordet Institute Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People who have cancer that has spread to the liver, confirmed by standard scans such as MRI or FDG PET/CT - People who have either not yet received any cancer treatment, or who have completed chemotherapy given before surgery - People whose medica...
NCT07116486 · M.D. Anderson Cancer Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed through specific imaging results, blood test findings, or a tissue biopsy - People whose liver cancer has been identified through detailed scan results that meet certain recognis...
NCT07118202 · Barbara Ann Karmanos Cancer Institute Not Applicable · 1 country
Who might be able to join this trial: - People who have advanced liver cancer (a liver tumour that cannot be treated with local treatments due to how far it has spread, or a liver tumour that came back after local treatment was done) - People whose cancer has not responded to at least two previous treatments, who are n...
NCT07119957 · University Hospital, Angers Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a fatty liver disease related to metabolic causes, alcohol use, or a combination of both (known by terms such as MASLD, ALD, or MetALD) - People who have had a liver biopsy within the last 2 months, or who have one planned, either to confirm ci...
NCT07122089 · Center Eugene Marquis Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People whose general health and ability to carry out daily activities meets a certain minimum standard (rated 0 or 1 on a medical scale called ECOG — confirm with trial site what this means for a specific situation) - People who have been diagnosed...
NCT07123545 · Zhejiang University Phase 2 · 1 country
Who might be able to join this trial: - People aged 18 to 75 years old - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma) confirmed by a tissue biopsy or sample - People whose cancer can be measured on a scan using standard medical criteria - People whose cancer has continued to grow...
NCT07132515 · Mansoura University Phase 4 · 1 country
Who might be able to join this trial: - People who have a blood clot in the portal vein (the main vein carrying blood to the liver) - People who have cirrhosis (scarring of the liver) - People with or without liver cancer (hepatocellular carcinoma) - People whose liver disease is rated as Child-Pugh class A or B, meani...
NCT07141056 · Guilin Medical University, China Not Applicable · 1 country
Who might be able to join this trial: This trial has three groups (cohorts). Each group has its own set of criteria. **Group 1 (SOLACE-1):** - Adults aged 18 or older - Able to complete psychological questionnaires - Liver function rated as Child-Pugh class A (a measure showing the liver is still working reasonably w...
NCT07142213 · Haitao Zhao, MD Not Applicable · 1 country
Who might be able to join this trial: - Adults between 18 and 75 years of age - People who have been diagnosed with a liver or bile duct cancer (such as hepatocellular carcinoma or cholangiocarcinoma) and whose doctors have assessed them as suitable for a specific two-stage liver surgery called ALPPS - People whose liv...
NCT07145177 · University of California, San Francisco Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy). - People whose prostate cancer has continued to grow or spread, as measured by specific medical criteria (called PCWG3) at the time of joining. - Male participants who are 18 year...
NCT07145801 · Thomas Jefferson University Phase 2 · 1 country
Who might be able to join this trial: - You are scheduled to receive a specific type of liver-targeted radiation treatment (called TARE) for liver cancer that has not been treated before and can be seen on an ultrasound scan. - You are at least 18 years old. - You are in a generally stable condition of health. - If you...
NCT07147101 · Fudan University Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older when you enter the study - You have been diagnosed with liver cancer (HCC) that is at an advanced stage, or at an intermediate stage that cannot be treated with surgery or local treatments - Your liver cancer has been confirmed by a scan, biop...
NCT07147335 · The First Affiliated Hospital of University of South China Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cirrhosis and chronic hepatitis (long-term liver inflammation) - People aged between 18 and 75 years, of any gender - People who are willing to take part in the study and have signed a consent form agreeing to participate - People who...
NCT07148050 · Seattle Children's Hospital Phase 1 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with a solid tumour that has a specific protein on it called GPC3. - You are able to carry out at least some daily activities independently, as measured by a standard performance score (confirm with trial site). - Doctors expect you to live for more t...
NCT07148310 · Epiliquid Holding, Inc Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a tissue sample, OR you have been diagnosed with liver cirrhosis (scarring of the liver) without liver cancer (as a comparison group) - You are willing and able to give your informed agreement to ta...
NCT07150624 · Anhui Provincial Hospital Phase 4 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) through scans and blood tests, and your doctors believe you can have keyhole (laparoscopic) surgery to remove part of your liver - Your planned surgery involves removing either a larger portion of t...
NCT07154082 · Wei Zhang Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue or cell sample test. - People who have not yet received any treatment for their cancer, including surgery, radiation, chemotherapy, immunotherapy, or targeted therapy. - Pe...
NCT07157969 · Peking Union Medical College Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who are willing to take part voluntarily, sign a consent form, and attend follow-up appointments as required. - People aged 18 or older at the time of signing the consent form, of any gender. - People who have been diagnosed with hepatocellular carcinoma (a type of liver c...
NCT07159048 · Fudan University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with primary liver cancer (hepatocellular carcinoma) or cancer that has spread to the liver from elsewhere, confirmed either by clinical assessment or tissue testing - People whose liver tumours are eac...
NCT07160946 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who test positive for the Hepatitis B surface antigen (a marker showing Hepatitis B infection) AND who also meet at least one of the following conditions: - Imaging scans (ultrasound, CT, or MRI) show signs of liver cirrhosis (scarring of the liver) - A diagnosis of Type 2...
NCT07169656 · The First Affiliated Hospital of Zhengzhou University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have had a chronic hepatitis B infection for 6 months or more (confirmed by a positive HBsAg test) - People aged 18 years or older - People who are currently receiving, or are planned to receive, one of the following hepatitis B treatments in routine clinical care:...
NCT07170345 · Chinese Academy of Sciences Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have a confirmed diagnosis of hepatocellular carcinoma (a type of primary liver cancer), diagnosed according to specific Chinese clinical guidelines - People whose liver cancer has been assessed as suitable for surgery — ei...
NCT07172282 · Northwell Health Early Phase 1 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who are able to give written consent to participate in the study. - People who have been confirmed by imaging to have colon or rectal cancer that has spread (metastasized) to the liver, and where surgery to remove those liver tumors is considered poss...
NCT07173868 · Samsung Medical Center Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 19 years of age or older - People who have been diagnosed through a tissue sample (biopsy) with breast cancer that has spread to other parts of the body or has grown locally to a point where surgery or radiation to remove it fully is not possible - People who h...
NCT07174570 · Emory University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by laboratory analysis of tissue or cell samples, and who are planned for treatment at Emory University's Winship Cancer Institute or Grady Cancer Center. - People whose cancer can be measu...
NCT07175441 · Riboscience, LLC. Phase 2 · 1 country
Who might be able to join this trial: - People who are at least 18 years old at the time of signing the consent form - People with advanced liver cancer that cannot be surgically removed, who are suitable to receive a specific combination treatment called the STRIDE regimen as their first treatment - People who are wil...
NCT07176650 · Shanghai Henlius Biotech Phase 1 · 2 countries
**Who might be able to join this trial:** - People who have signed a written consent form approved by the relevant ethics board. - People aged between 18 and 65 years old at the time of signing the consent form. - People who weigh between 50 kg and 85 kg. - People who have been diagnosed with hepatocellular carcinoma...
NCT07177742 · Mu-qing Yang Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 19 and 80 years old (any gender) - People who are able to attend all required study visits and follow the study plan - People who are willing to take part and sign a consent form - People who have been diagnosed with colon adenocarcinoma (a specific type o...
NCT07178093 · Taichung Tzu Chi Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a consent form agreeing to take part in the trial - People aged between 20 and 80 years old - People whose liver function falls into Category A or B on a standard liver health scoring system called Child-Pugh (confirm with trial site) -...
NCT07186010 · Asan Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (called HCC) confirmed by a tissue sample test - People whose liver cancer has spread, come back, or cannot be removed, and where surgery, liver transplant, or a heat-based tumour treatment (radiofrequency ablation) have been ruled...
NCT07186621 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 3 · 1 country
**Who might be able to join this trial:** - You had surgery to completely remove liver cancer (hepatocellular carcinoma), and the edge of tissue removed around the tumor was less than 1 cm wide, confirmed by lab results, surgical notes, and scans - Your surgery took place within the last 4 months - You have at least o...
NCT07193862 · Northwell Health Early Phase 1 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with colorectal cancer (confirmed by a lab test on tissue) and scans show it may have spread to the liver - The liver tumor is at least 2 cm in size, as seen on a CT or MRI scan - Your doctors have already planned surgery to remove part of your liver...
NCT07219459 · CatalYm GmbH Phase 2 · 4 countries
Who might be able to join this trial: - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that cannot be surgically removed or has spread, and where curative treatment is not possible. - People whose cancer can be measured on scans, as assessed by the treating doctor and a radiologist....
NCT07224724 · City of Hope Medical Center Not Applicable · 1 country
Who might be able to join this trial: - You must be an adult aged 18 or older - You have been diagnosed with colorectal cancer that has spread to other parts of the body, confirmed through a tissue or cell sample test - Blood samples taken before treatment are available for use in the study - You are willing and able t...
NCT07226869 · NE Scientific INC Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who are expected to live for at least one year - People who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed through specific imaging results, a tissue biopsy, or through a combination of liver scarring (cirrhosis) and a rai...
NCT07227012 · Pfizer Phase 2 · 4 countries
**Who might be able to join this trial:** - People who are 18 years of age or older at the time of screening - People who have been diagnosed with advanced or metastatic liver cancer (hepatocellular carcinoma), confirmed either by tissue/cell sample testing or, for those with liver scarring (cirrhosis), by established...
NCT07235410 · Union Hospital, Tongji Medical College, Huazhong University of Science... Not Applicable · 1 country
Who might be able to join this trial: - People who were diagnosed with hepatocellular carcinoma (a type of liver cancer) between January 1, 2018 and May 31, 2024 - People who were over 18 years old at the time of diagnosis Who may not be able to join: - People whose medical imaging scans are of poor or unusable qualit...
NCT07239245 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed, or are able to sign, an informed consent form for the study - People aged 18 to 75 years old at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by a tissue biopsy -...
NCT07242417 · Beijing GoBroad Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - You are willing and able to sign a consent form agreeing to take part in the study - You are between 18 and 75 years old (inclusive) - Your doctors expect you to live for at least 12 weeks - You are generally well enough to carry out light activity and care for yourself (conf...
NCT07246668 · Yonsei University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by biopsy or imaging, at a stage classified as BCLC B or C, where curative surgery or a liver transplant is not an option - People who have at least one...
NCT07252323 · Yonsei University Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 20 or older who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed by imaging or tissue testing - People who have had a previous TARE treatment (a type of internal radiation therapy for liver cancer) and still have remaining cancer, or wh...
NCT07263217 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with cholangiocarcinoma (a type of cancer affecting the bile ducts in the liver). - Your liver is functioning at a good level, classified by doctors as "Child-Pugh Class A" (confirm with trial site). - You are planned to receive a specific combination...
NCT07265271 · City of Hope Medical Center Not Applicable · 1 country
Who might be able to join this trial: - Adults between 18 and 100 years of age - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed through a laboratory tissue test - People who have a clinically diagnosed long-term liver condition, such as chronic hepatitis or liver cirrhosis, but wi...
NCT07267806 · Linhui Peng Phase 3 · 1 country
**Who might be able to join this trial:** - People who have voluntarily agreed to take part and have signed a consent form. - Adults aged 18 or older, of any gender. - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue or cell testing, or by clinical diagnosis. -...
NCT07272200 · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with non-alcoholic fatty liver disease (NAFLD) or an unexplained liver condition, including those who drink moderate amounts of alcohol (up to 60g per day for men or 40g per day for women) - Male patients who have type 2 diabetes or obesity and...
NCT07274774 · Shandong Cancer Hospital and Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 70 years - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed either by tissue testing or according to national clinical guidelines - People whose liver cancer is classified as an advanced stage (BCLC st...
NCT07275073 · Shanghai JMT-Bio Inc. Phase 1 · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People who have been diagnosed with an advanced solid tumour, confirmed through a tissue or cell sample. - People whose cancer has not responded to at least one standard treatment, for whom no standard treatment is available, or who were unable to toler...
NCT07280143 · University of Bern Not Applicable · 1 country
Who might be able to join this trial: - You must be willing and able to sign a consent form to take part in the study - You must be 18 years old or older - You must have been diagnosed with breast cancer or colorectal cancer at least 5 years ago, but no more than 10 years ago, with no return of cancer or new cancer dia...
NCT07282184 · Tongji Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People between 18 and 75 years of age who are able to understand and sign a consent form voluntarily. - People who have been diagnosed with early-stage liver cancer (BCLC stage 0 or A), confirmed by tissue testing or approved imaging methods. - People who are already schedul...
NCT07284836 · Zhejiang Cancer Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who have breast cancer that has spread to the liver, confirmed by surgery or biopsy. - People with advanced breast cancer where the cancer that has spread to organs is found only in the liver, as confirmed by medical imaging. - People who have already tried at least two pr...
NCT07285850 · Eastern Hepatobiliary Surgery Hospital Phase 3 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older (any gender) - You are generally able to carry out light activity and care for yourself, but may not be able to do heavy physical work (confirm with trial site) - Scans have shown you have advanced liver cancer that is not suitable for surger...
NCT07291141 · Mattias Ekstedt Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cirrhosis (scarring of the liver), confirmed through methods such as an elastography scan, symptoms, a biopsy, or imaging scans. - People aged 18 to 84 years old. - People who are willing and able to provide written consent to take part....
NCT07295262 · West China Hospital Early Phase 1 · 1 country
Who might be able to join this trial: - You are between 18 and 75 years old - You have been newly diagnosed with liver cancer (hepatocellular carcinoma) for the first time — not a recurrence - Your tumor is a single tumor measuring 5 cm or less in size - At least two experienced senior liver surgeons have agreed that y...
NCT07295275 · West China Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are between 18 and 80 years old - After your surgery, tests on the removed tissue confirmed you have liver cancer (specifically hepatocellular carcinoma, or HCC) - You had a type of keyhole (laparoscopic) liver surgery that used a special glowing dye (ICG fluorescence) to...
NCT07302919 · University Hospital, Basel, Switzerland Phase 3 · 1 country
**Who might be able to join this trial:** - People who have signed a consent form agreeing to take part in the study - People aged 18 or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either by a tissue biopsy or by CT or MRI scan using standard diagnostic crite...
NCT07303712 · Palo Alto Veterans Institute for Research Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by imaging scans, at an early to intermediate or locally advanced stage (classified as BCLC stage 0, A, B, or C) - People whose case has been...
NCT07303725 · Palo Alto Veterans Institute for Research Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have a tumor in an area of the body that has not previously been treated with surgery or ablation (a procedure that destroys tissue) - People who have at least one tumor that measures more than 1.5 cm (roughly half an inch) at...
NCT07305428 · The University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with liver cancer (hepatocellular carcinoma/HCC) based on specific imaging scans (CT or MRI) showing a liver nodule larger than 1cm with particular patterns, and you have either liver scarring (cirrhosis) or chronic hepatitis B infection - Your liver tumor...
NCT07310173 · Zhejiang Hisun Pharmaceutical Co. Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma) confirmed by a pathology test. - People whose cancer has continued to grow or spread after receiving prior treatment that included immunotherapy (immune checkpoint inhibitors), confirmed by...
NCT07310537 · Erasmus Medical Center Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 21 years of age or older - People who have a confirmed diagnosis of colorectal adenocarcinoma (a type of bowel cancer), including cases that have spread to other parts of the body - People who currently have colorectal cancer that has spread to the liver and is...
NCT07312292 · Niek Wijnen Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver tumors, either starting in the liver or spreading there from elsewhere in the body (any tumor type). - People for whom a liver treatment called radioembolization (a procedure that delivers radiation directly to liver tumors through b...
NCT07315633 · University Hospital, Ghent Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with liver cancer (called HCC) through medical imaging, and who are receiving or are planned to receive treatment. - People who are being treated (or will be treated) with a procedure called TARE, which involves delivering tiny radioactive beads thr...
NCT07322848 · First Affiliated Hospital, Sun Yat-Sen University Phase 3 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with liver cancer (hepatocellular carcinoma) that is beyond certain size limits — either a single tumor larger than 5 cm, or three or more tumors with at least one being 3 cm or larger, all within the liver and without spread to other parts of the body...
NCT07324824 · Sun Yat-sen University Phase 2 · 1 country
Who might be able to join this trial: - People who are able to understand the study and are willing to sign a consent form - People who are 18 years of age or older - People who have been diagnosed (either through clinical assessment or tissue testing) with liver cancer (hepatocellular carcinoma) that can be removed by...
NCT07327034 · Abbisko Therapeutics Co, Ltd Phase 2 · 1 country
Who might be able to join this trial: - People aged 18 or older at the time of signing the consent form who are willing and able to attend study visits and follow the study procedures - People with advanced or inoperable liver cancer (hepatocellular carcinoma, or HCC) confirmed by biopsy, cell testing, or clinical asse...
NCT07327489 · Elephas Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to agree to take part in the trial by giving their consent. - People who are 18 years of age or older at the time they give consent. - People who have a suspected or confirmed cancer diagnosis that a doctor has recommended investigating with a biop...
NCT07327788 · Nanfang Hospital, Southern Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to sign a consent form agreeing to take part in the study - Adults aged 18 or older — both men and women are eligible - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either through clinical assessment or laborat...
NCT07328009 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of joining the study. - People who have given written consent to participate. - People with liver cancer (hepatocellular carcinoma, or HCC) that has spread locally, to other parts of the body, or cannot be removed by surgery, confirmed by...
NCT07331883 · Ruijin Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years (any gender) who are willing and able to give written consent before any trial procedures begin, or whose legal representative is able to do so on their behalf. - People whose liver cancer (hepatocellular carcinoma, or HCC) was confirmed by a patho...
NCT07337421 · Northern Jiangsu People's Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a tissue or cell sample, and you have not received any treatment for it before surgery (such as chemotherapy, targeted therapy, immunotherapy, radiation, o...
NCT07337460 · Northern Jiangsu People's Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by laboratory testing of tissue or cells, and who have not received any treatment for this cancer before surgery (including chemotherapy, targeted...
NCT07343960 · AstraZeneca Phase 1 · 1 country
**Who might be able to join this trial:** - People who weigh at least 50 kg and have a Body Mass Index (BMI) between 18 and 40. - People who are willing to use contraception in line with local guidelines for clinical trial participants (or whose partners will do so). - People who have veins that are suitable for blood...
NCT07345247 · Ankara University Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People who have had a type of liver-targeted radiation treatment (called radioembolization) aimed at fully treating the cancer, with either a single tumor or fewer than 3 tumors located in the same or nearby areas of the liver - People who have can...
NCT07351669 · Zhongda Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed either by a tissue sample or by standard medical imaging and clinical assessment - Your liver cancer is classified as an early or intermediate stage (known as...
NCT07356531 · JIANGSU SHENMING Medical Technology CO., Ltd Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 to 80 years old, of any gender - People who have been diagnosed with a type of liver cancer called hepatocellular carcinoma (either confirmed by tissue testing or by clinical assessment) and whose doctors have determined that a procedure called TACE (a treatment th...
NCT07358910 · Institut Pasteur du Cambodge Not Applicable · 1 country
Who might be able to join this trial: - You must have been living in the village for more than 6 months - You must be between 2 and 75 years old at the time of joining the trial - Adults must be able to provide written consent to participate - For children aged 2 to 17 years, a parent or guardian must provide written c...
NCT07364357 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Phase 1 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old. - People who have been diagnosed with liver cancer (hepatocellular carcinoma) that has been confirmed by a tissue sample, and whose cancer is at an advanced stage or cannot be treated with curative intent. - People who have hepatitis...
NCT07364474 · Massachusetts General Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been confirmed by laboratory testing (tissue or cell sample) to have uveal melanoma (a type of eye cancer) that has spread to the liver, and who have been assessed as a suitable candidate for a liver perfusion procedure using a chemotherapy drug called melpha...
NCT07365527 · Zealand University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People who are able to give written consent to participate - People who have been diagnosed with colorectal adenocarcinoma (a specific type of bowel cancer), confirmed through tissue testing - People who are scheduled for surgery or ablation (a proc...
NCT07365930 · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has been confirmed by a tissue sample, and where the cancer has spread or cannot be surgically removed. - People whose liver cancer is also accompanied by liver cirrhosis (scarring of th...
NCT07377487 · Boston Scientific Corporation Not Applicable · 1 country
**Who might be able to join this trial:** - Adults who are 18 years of age or older at the time of giving consent - People who are willing and able to take part and have signed a written consent form - People whose case has been reviewed by a specialist team (multidisciplinary board) and who have been found to have no...
NCT07378709 · University of Belgrade Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either through specialised liver imaging (CT or MRI) or a tissue biopsy - People whose liver cancer has been assessed by their medical team as suitable f...
NCT07391839 · Suzhou Mednovo Yi Medical Technology Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing to take part and sign a consent form agreeing to join the study. - People aged 18 to 80 years old (inclusive), of any gender. - People who have been diagnosed with liver cancer (hepatocellular carcinoma) either through clinical assessment or confirmed...
NCT07392567 · Tongji Hospital Not Applicable · 1 country
Who might be able to join this trial: - People aged between 18 and 75 years, of any gender - People who have been diagnosed with primary colon or rectal cancer (a specific type called adenocarcinoma) at an early to intermediate stage (Stage I, II, or III), and who are planned to have surgery to remove the cancer with t...
NCT07393074 · Hospices Civils de Lyon Not Applicable · 1 country
**Who might be able to join this trial:** **Group A (people with cirrhosis, without suspected liver cancer):** - Adults aged 18 or older - Enrolled in the French social security system - Able to hold a conversation and read in French - Willing and able to sign a consent form - Diagnosed with a stable, well-managed for...
NCT07398326 · Shanghai Changzheng Hospital Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with advanced colorectal cancer (a type of bowel cancer) confirmed by laboratory testing of tissue or cell samples. - People whose cancer has spread to areas other than the liver, and who have clearly decided they do not want chemotherapy. - People...
NCT07399236 · Tongji Hospital Not Applicable · 1 country
Who might be able to join this trial: - People between 18 and 75 years old, of any gender - People who have been diagnosed with colon or rectal cancer (specifically a type called adenocarcinoma), confirmed through laboratory testing of tissue - People who have had surgery to fully remove their colorectal cancer, with t...
NCT07405086 · OHSU Knight Cancer Institute Phase 4 · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form before any study procedures begin - People aged 18 years or older - People who have been diagnosed (through laboratory tissue testing) with an advanced or spreading solid tumour that is one of the following types:...
NCT07408804 · Bangladesh Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with liver cancer (hepatocellular carcinoma), confirmed by specialist imaging (such as a CT scan or MRI) or a tissue biopsy, and whose cancer falls into an early, intermediate (a specific subgroup), or a...
NCT07413354 · Tongji Hospital Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) confirmed by tissue testing - People whose liver cancer is at an advanced stage (BCLC stage C), or at an intermediate stage (BCL...
NCT07413640 · Central Hospital, Nancy, France Not Applicable · 1 country
Who might be able to join this trial: - People who are adults (18 years or older) - People who have had a liver treatment called microwave ablation, carried out through the skin using CT or ultrasound imaging as a guide - People who were treated for one or more lesions (abnormal areas) in the liver - People who have fo...
NCT07417800 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a laboratory examination of tissue - You are older than 18 years of age - You have had surgery to completely remove your liver cancer, with no cancer cells left at the edges of the removed tissue (k...
NCT07419841 · Compass Therapeutics Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 years or older. - People who have been diagnosed with one of four specific cancer types — kidney cancer (renal cell carcinoma with clear cell component), liver cancer (hepatocellular carcinoma), stomach or oesophageal cancer (gastroesophageal cancer), or uteri...
NCT07422753 · Second Affiliated Hospital, School of Medicine, Zhejiang University Phase 2 · 1 country
Who might be able to join this trial: - People who have signed and dated a written consent form before any trial-related procedures begin - People who have been clinically confirmed to have liver cancer (hepatocellular carcinoma) that cannot be surgically removed or has spread to other parts of the body - People aged 1...
NCT07429864 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not Applicable · 1 country
Who might be able to join this trial: - People who have chronic hepatitis or mild, stable liver cirrhosis caused by the hepatitis D virus (HDV) - People who have tested positive for HDV in their blood within the 24 weeks before joining the trial - People who are already taking antiviral medication for hepatitis B (HBV)...
NCT07445412 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - You must be willing and able to give your consent to take part in the trial - You have a tumour in your liver (either non-cancerous or cancerous) and your medical team has decided that not enough healthy liver tissue would remain after surge...
NCT07459309 · Fudan University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 to 80 years, of any gender - People who have been diagnosed with liver cancer (either starting in the liver or spreading to the liver from elsewhere), confirmed by tissue testing or clinical assessment - People who have at least one liver tumour that can be me...
NCT07467434 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People diagnosed with a specific type of rectal cancer (adenocarcinoma) located in the middle and/or lower part of the rectum, with certain tumour or lymph node characteristics (classified as pMMR T3, T4, and/or N+) (confirm with trial site) - Peop...
NCT07469319 · University of Aarhus Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with cirrhosis (scarring of the liver) - You do not have a history of chronic hepatitis B or C - Your cirrhosis is considered "compensated," meaning you have not had recent bleeding from swollen veins in your digestive tract, your fluid build-up in the abd...
NCT07473687 · Taipei Veterans General Hospital, Taiwan Not Applicable · 1 country
Who might be able to join this trial: - You are 18 years of age or older - You are scheduled to have a surgery that requires general anesthesia (being fully asleep during the procedure) - Your overall health falls within a certain range as assessed by your doctor (this is a standard health rating system used by anesthe...
NCT07476651 · Seoul National University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 19 years or older - People who have been diagnosed with liver cancer (hepatocellular carcinoma) through imaging or biopsy, bile duct cancer within the liver (intrahepatic cholangiocarcinoma) confirmed by biopsy, or cancer that has spread to the liver from elsewhe...
NCT07478302 · Suzhou Suncadia Biopharmaceuticals Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with advanced liver cancer (hepatocellular carcinoma), confirmed by tissue testing, cell testing, or medical assessment - People whose liver cancer has been staged as Barcelona stage B or C (a system doctors use to asse...
NCT07482059 · West China Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have liver cancer (hepatocellular carcinoma, or HCC) that cannot be surgically removed, or who have chosen not to have surgery, with no spread of cancer outside the liver (although spread to nearby lymph nodes is permitted) - People whose liver cancer has been con...
NCT07485114 · Daniel Keizman Not Applicable · 1 country
**Who might be able to join this trial:** - People who are able to read, understand, and follow the study's consent and requirements - People aged 18 years or older - People who have been diagnosed with one of these cancers: renal cell carcinoma (a type of kidney cancer), transitional cell carcinoma (a cancer affecting...
NCT07489976 · Ju Dong Yang Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older at the time of signing the consent form. - People diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has grown beyond certain size/spread limits (called UCSF criteria), confirmed by tissue sample, imaging, or standard clinical assessment,...
NCT07493668 · CHA University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has spread or cannot be surgically removed, confirmed by imaging, tissue sample, or cell sample - People who have already received at least 2 rounds of a first-line immunotherapy combina...
NCT07495215 · Yinghua Xu Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old at the time of signing the consent form. - People who have been diagnosed with liver cancer (hepatocellular carcinoma) confirmed by a lab test, where the cancer was able to be fully removed by surgery with clear margins, no spread to blood vess...
NCT07500220 · Beijing Biotech Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years. - People with liver cancer (hepatocellular carcinoma) that has been confirmed by tissue or cell testing, or by imaging scans with mandatory tissue confirmation before joining. - People whose liver cancer cannot be removed by surgery, has spread, o...
NCT07536789 · Fudan University Phase 2 · 1 country
Who might be able to join this trial: - People who have given written agreement to take part in the study. - People aged 18 or older at the time of joining the study. - People who have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC) that has spread or cannot be surgically removed, confirmed either t...
NCT07538882 · Beijing Tsinghua Chang Gung Hospital Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People who have been recently diagnosed with, or are suspected of having, primary liver cancer (a cancer that started in the liver), later confirmed by tissue testing or according to recognised Chinese liver cancer guidelines. - People who have a comple...
NCT07544784 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People who have been confirmed through a tissue or cell sample to have colorectal cancer (bowel cancer) - People who have cancer that has spread to the liver, with at least one measurable area of cancer spread plus one liver tumour th...
NCT07547553 · Huahui Health Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years (inclusive), of any gender, who are willing to take part and have signed a consent form. - People who have been diagnosed with advanced or inoperable liver cancer (hepatocellular carcinoma, or HCC), confirmed either by tissue biopsy or by clinical...
NCT07560488 · Tianjin Medical University Cancer Institute and Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent before any study procedures begin - People aged 18 to 75 years, of any gender - People who have been diagnosed with hepatocellular carcinoma (a type of primary liver cancer), either through clinical assessment or confirmed by tissue or c...
NCT07587216 · Tongji Hospital Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older at the time of signing the consent form - People who have been diagnosed with liver cancer, either through medical assessment or confirmed by a laboratory tissue test - People who are receiving treatment and follow-up care at Tongji Hospital Who may not b...
NCT07589244 · Guangzhou Virotech Pharmaceutical Co., Ltd. Phase 3 · 1 country
**Who might be able to join this trial:** - You are willing to sign a consent form, understand what the study involves, and agree to follow all study procedures. - You are between 18 and 75 years old (inclusive) on the date you sign the consent form, regardless of gender. - You have been diagnosed with advanced liver c...
NCT07601464 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People who have been diagnosed with liver cancer (hepatocarcinoma), confirmed either through specific imaging scans or a tissue biopsy. - People for whom a heat-based tumour destruction treatment (called radiofrequency ablation) has been recommended by...
NCT07602504 · Anhui Provincial Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with cancer that has spread to the liver, confirmed either by tissue testing or imaging scans. - People who are 18 years of age or older. - People who have willingly agreed to take part and signed a consent form. - People who have a complete set of...
NCT07607769 · AstraZeneca Not Applicable · 1 country
Who might be able to join this trial: - You must be willing and able to sign a consent form to take part in the study. - You must be 18 years old or older. - You must have been diagnosed with advanced or inoperable liver cancer (hepatocellular carcinoma, or HCC), confirmed by tissue sample or imaging scans. - Your live...
NCT07610551 · Air Force Military Medical University, China Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years old or older - You have been diagnosed with liver cancer (HCC) that cannot be removed by surgery, either confirmed by a doctor's assessment or by a tissue sample - You have received at least one dose of the drug combination Atezolizumab plus Bevacizumab and c...
NCT07623265 · Universitaire Ziekenhuizen KU Leuven Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older, of any sex - People who have been diagnosed with, or are suspected to have, a type of liver cancer called hepatocellular carcinoma (HCC), based on medical scans **For Group 1 (people with past treatment records — may include historical data):** - Pe...
NCT07639138 · Shunda Du Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 to 75 years old - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), either through clinical assessment or tissue testing - People whose liver cancer cannot be removed by surgery, has spread to nearby areas, or has spread to othe...
NCT07642336 · Nguyen Toan Thang Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 80 years of age. - People whose overall physical health before surgery falls within a standard medical fitness range known as ASA Class I to III (confirm with trial site for what this means in your situation). - People who are already scheduled to have a...
NCT07657897 · Iuliu Hatieganu University of Medicine and Pharmacy Not Applicable · 1 country
**Who might be able to join this trial:** - People who have liver cancer (hepatocellular carcinoma) that is suitable for treatment with a procedure called radiofrequency ablation (RFA), which uses heat to destroy cancer cells - People whose tumor is no larger than 3 cm (about the size of a grape) across - People who ha...
NCT07677774 · The First Affiliated Hospital of Xiamen University Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have suspected, newly diagnosed, or previously treated liver cancer (hepatocellular carcinoma), supported by imaging results or pathology reports - People who are willing and able to provide signed consent, or who have a parent...
NCT07679061 · Bristol-Myers Squibb Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that cannot be removed by surgery and is not suitable for — or has continued to grow after — local treatmen...
Advocacy and support in Australia
Organisations that can offer information, support, or connection for Liver Cancer. Where more than one is listed, they serve different needs or regions, so choose whichever fits your situation.
The Liver Foundation is the national body for liver cancer, alongside its broader liver health work.
This is a starting point, not medical advice or an endorsement. Contact details change; search the organisation name to find its current website.