Pancreatic Cancer

**Who might be able to join this trial:** - You have been diagnosed with pancreatic cancer (specifically adenocarcinoma) that has spread to other parts of the body (metastatic), confirmed by a tissue or cell sample - Your diagnosis of metastatic disease was made no more than 6 weeks before joining the study - At least...

Who might be able to join this trial: - You have been diagnosed with pancreatic cancer (specifically adenocarcinoma) that has spread to other parts of the body and has not yet been treated. - Your blood counts, kidneys, and liver are working well enough to meet the trial's health requirements. - You are generally able...

**Who might be able to join this trial:** - People who have a tumour that can be measured, that is accessible for a biopsy, and who are willing to have two biopsies (one before treatment and one during treatment), and can provide stored tumour tissue if it is available. - People who are generally well enough to carry...

Who might be able to join this trial: - People who are at least 12 years old (or at least 18 years old for a specific group called Cohort B1) - People who have been diagnosed with one of the following: advanced or metastatic pheochromocytoma/paraganglioma (tumours of the adrenal gland or nearby nerve tissue), pancreati...

**Who might be able to join this trial:** This trial involves a registry called PRECEDE for people being assessed for pancreatic cancer (PDAC) risk. There are several groups that may be eligible: - People with no personal history of pancreatic cancer who have two or more relatives with pancreatic cancer on the same s...

**Who might be able to join this trial:** - Adults aged 18 or older (or the legal age of majority in the country where the trial is being run) at the time of giving consent. - People who are willing and able to understand, sign, and date a written consent form before any trial procedures begin. - People with a general...

**Who might be able to join this trial:** - People who have been diagnosed with metastatic pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer that has spread), confirmed by a tissue or cell sample. - People who have not yet received treatment for their metastatic disease, whose metastatic diagnosis...

Who might be able to join this trial: **General requirements (all modules):** - People whose cancer is currently progressing at the time of enrolment - People who are well enough to carry out daily activities, with no worsening in the two weeks before enrolment (as measured by a standard performance scale) - People wh...

Who might be able to join this trial: - People who are 18 years of age or older. - People who have a locally advanced or spreading solid tumour cancer that has a specific genetic change called a KRAS G12D mutation. - For certain parts of the trial: People whose cancer has continued to grow despite previous standard tre...

**Who might be able to join this trial:** - People who have a confirmed solid tumour (by lab testing of tissue or cells) that has spread or cannot be surgically removed, and whose tumour has a specific genetic change called a KRAS G12C mutation - People whose cancer has continued to grow during or after standard treat...

**Who might be able to join this trial:** - Adults aged 18 or older who had a type of major surgery called a Whipple's procedure (removal of part of the pancreas and surrounding structures) between April 2018 and December 2023, with the goal of curing their condition, and who received their post-surgery care at Royal P...

**Who might be able to join this trial:** - Adults aged 18 or older who have a well or moderately differentiated neuroendocrine tumour (NET) of the mid-gut, hind-gut, or pancreas that has spread to other parts of the body and cannot be removed by surgery, and whose tumour has continued to grow despite receiving a soma...

**Who might be able to join this trial:** - You have colorectal cancer that cannot be removed by surgery or has spread to other parts of the body, and you have already received at least one previous cancer treatment - You have advanced or metastatic pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer...

**Who might be able to join this trial:** **For the colorectal cancer group:** - Adults aged 18 or older (or the legal age of consent in the country where the trial is taking place) - People with a confirmed diagnosis of advanced colon or rectal cancer that cannot be surgically removed, either because it has spread lo...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form - People with breast cancer who have received at least one prior chemotherapy treatment (either before surgery, after surgery, or for advanced/spread disease), and hormone therapy if their cancer...

**Who might be able to join this trial:** - People who are 18 years of age or older (or the legal age of consent in the country where the study takes place) at the time of signing the consent form. - People who have at least one tumour that can be measured using standard imaging criteria (known as RECIST 1.1). - People...

**Who might be able to join this trial:** - You have been diagnosed with a specific type of advanced cancer (non-small cell lung cancer, pancreatic cancer, colorectal cancer, or another solid tumor) that has spread or cannot be surgically removed, and your tumor has been confirmed by a lab test to have a specific gene...

**Who might be able to join this trial:** - People who have been diagnosed (confirmed by laboratory tissue testing) with a neuroendocrine tumour (NET) that started in the pancreas or another part of the body, and the tumour is either advanced, cannot be surgically removed, or has spread to other parts of the body, and...

**Who might be able to join this trial:** - You have signed a consent form agreeing to take part in the study - You have been diagnosed with pancreatic cancer that has spread to other parts of the body (specifically a type called pancreatic ductal adenocarcinoma) - You have been experiencing significant unintentional w...

Who might be able to join this trial: - You must be 18 years of age or older. - You must be willing and able to sign a consent form approved by an ethics review board. - You must have a solid tumor (cancer) that has been confirmed by lab testing to have a specific genetic change called a KRAS G12D mutation, and the can...

**Who might be able to join this trial:** - People who have been assessed and found to have an adjustment disorder (a stress-related condition) based on specific questionnaire scores, including a distress score of 4 or higher on a standard scale. - People whose anxiety has been measured as moderate or higher on a stan...

**Who might be able to join this trial:** - You must be 18 years of age or older (or meet the legal adult age in your country, if that is older than 18). - You have been diagnosed with an advanced or spread-out cancer that has a specific type of gene change (called a "missense mutation") or extra copies of a gene call...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People whose cancer type has no currently available treatment known to be effective - People who have been formally diagnosed (through tissue or cell testing) with an advanced or spreading solid tumour cancer that has stopped responding to...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been diagnosed with metastatic pancreatic adenocarcinoma (a specific type of pancreatic cancer that has spread to other parts of the body), confirmed within the last 12 weeks before screening - People whose general physical hea...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed by laboratory testing of tissue samples - People who have at least one area of cancer that can be measured on a scan, according to a standard set of measure...

Who might be able to join this trial: - Adults aged 18 or older with a body weight between 40 kg and 100 kg. - People who have been diagnosed with a specific type of pancreatic cancer called ductal adenocarcinoma that has spread to other parts of the body (metastatic), diagnosed within the past 4 months (Part A) or wit...

**Who might be able to join this trial:** - You have been diagnosed with a neuroendocrine tumour (NET) of the pancreas or the middle part of the small intestine (midgut), confirmed by a tissue sample, that is either grade 1 or grade 2, and has spread to other parts of the body or cannot be removed by surgery. - Your tu...

**Who might be able to join this trial:** - You have been diagnosed with locally advanced pancreatic cancer, confirmed by a CT or MRI scan and a tissue biopsy - You have not received any treatment for your pancreatic cancer before the radiation treatment used in this trial (called SBRT) - Your doctors expect you to li...

**Who might be able to join this trial:** - You are 18 years of age or older - You own and use a smartphone that works with the Dexcom G6 app - You have access to the internet - You scored above a certain level on a short memory and thinking test (the exact score required depends on your level of education — confirm wi...

**Who might be able to join this trial:** - You are 20 years old or older - You are willing and able to sign and date a consent form agreeing to take part - You are willing to follow all the steps of the registry and are available for the full duration of the study - You have been diagnosed with pancreatic cancer (conf...

**Who might be able to join this trial:** - You have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) that has not spread to other parts of the body, and cannot be removed by surgery straight away (classified as "borderline" or "locally advanced") - You have not yet had any surgery or chemo...

"Who might be able to join this trial: - You must be 18 years of age or older (male or female). - You must have a documented fasting blood sugar level below 55 mg/dl (measured after not eating for a period of time). - You must have lab test results suggesting an insulinoma (a type of tumor on the pancreas) or another t...

**Who might be able to join this trial:** - You have been diagnosed with one of the following inherited bone marrow failure conditions: Fanconi anemia, Diamond Blackfan anemia, Dyskeratosis congenita, Shwachman Diamond Syndrome, Amegakaryocytic thrombocytopenia, Thrombocytopenia absent radii, Severe Congenital Neutrop...

Who might be able to join this trial: - People who have been diagnosed with pancreatic adenocarcinoma (a type of pancreatic cancer), either confirmed by tissue sample or by a CT scan - People who have an abnormal result on an imaging scan of the pancreas area (such as a CT, MRI, or similar scan) - People who have been...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with pancreatic cancer, are suspected of having pancreatic cancer, or have a pre-cancerous growth in the pancreas - Adults aged 18 or older who have had two or more cancers linked to a condition called hereditary nonpolyposis c...

**Who might be able to join this trial:** - People diagnosed with stage I–IV colorectal cancer, or colorectal cancer that has come back (Arm 1) - People who can speak, read, and write in English (Pre-pilot phase, Arms 1–4) - People who are able to give informed consent to participate (Pre-pilot phase, Arms 1–4, PCS st...

Who might be able to join this trial: - You have been diagnosed with a benign (non-cancerous) or malignant (cancerous) tumor, or another condition that your doctor believes can be treated with a highly targeted type of radiation therapy (called stereotactic radiosurgery or stereotactic body radiotherapy). - You are wil...

**Who might be able to join this trial:** - People diagnosed with Hyperinsulinism (HI) who are receiving care at the Cook Children's Congenital Hyperinsulinism Center and are being treated by an Endocrinologist connected to the trial. - People whose Endocrinologist has determined that standard medications have not wor...

**Who might be able to join this trial:** **For pancreatic cancer patients:** - You have been diagnosed with pancreatic cancer that has been confirmed by a tissue sample (biopsy) - Your cancer has not spread to distant parts of the body, but is either too complex to remove with surgery right away ("locally advanced")...

**Who might be able to join this trial:** - You are 18 years of age or older and are scheduled to have surgery to remove part or all of your pancreas, or a nearby structure called the duodenum, for a suspected pancreatic condition - Your condition is one of the following: a type of pancreatic cancer (ductal adenocarcin...

Who might be able to join this trial: - People who are 18 years of age or older - People who have a confirmed inherited gene mutation in one of the following genes: BRCA1, BRCA2, ATM, or PALB2 - People with no close family history of pancreatic cancer (no parent, sibling, child, grandparent, aunt, uncle, niece, or neph...

Who might be able to join this trial: - You have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) that cannot be removed by surgery, confirmed by a biopsy. - Your cancer is either too difficult to remove surgically, you have health reasons that make surgery unsafe, or you have chosen not to...

Who might be able to join this trial: - Adults (over 18 years old) who have been diagnosed with pancreatic cancer and whose treating doctor has determined they are suitable for a soft tissue ablation procedure. Who may not be able to join: - People who have a cardiac pacemaker or an implanted heart defibrillator (ICD)...

**Who might be able to join this trial:** - You are 18 years of age or older - You have signed a consent form agreeing to take part in the study - You are not currently pregnant or breastfeeding - You are healthy enough to safely receive anesthesia (sedation for surgery) - You are scheduled to have one of two specific...

Who might be able to join this trial: - People who have been diagnosed with a pancreatic neoplasm (a tumour or abnormal growth on the pancreas) Who may not be able to join: - People who have been diagnosed with cholangiocarcinoma (a type of cancer that forms in the bile ducts) Important: Always verify eligibility wit...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer) that has spread to other parts of the body, confirmed by tissue sample and/or imaging scans — those without a tissue-confirmed diagnosis must have a biopsy done before starting...

"Who might be able to join this trial: - Adults over 18 years old - People who are having surgery for pancreatic cancer Who may not be able to join: - People who do not wish to take part in the study Important: Always verify eligibility with the trial site directly before applying."

**Who might be able to join this trial:** - You have been confirmed to have a condition called MEN1 (Multiple Endocrine Neoplasia type 1), whether this was diagnosed through clinical assessment, a genetic test, or because it runs in your family. - You have never previously been diagnosed with a pancreatic neuroendocrin...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with a type of pancreatic tumor (either a pancreatic neuroendocrine tumor or pancreatic ductal carcinoma) that is smaller than 5cm and was confirmed by a specific type of biopsy using a fine needle - You are not suitable for...

**Who might be able to join this trial:** - People who have at least 2 close family members (parents, siblings, or children) who have had pancreatic cancer. - People who have at least 3 family members across multiple generations who have had pancreatic cancer, with at least one of those being a close family member (pa...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed through a tissue or cell sample, with diagnosis made within 8 weeks of signing consent (or, for those joining at the second treatment cycle, from the start of that...

Who might be able to join this trial: - You must be over 18 years old - You have been diagnosed with pancreatic cancer (specifically a type called ductal adenocarcinoma) or a cancer near the opening of the small intestine (called ampullary adenocarcinoma), confirmed by examining tissue from surgery; OR you have had can...

**Who might be able to join this trial:** - You are 18 years of age or older (there is no upper age limit) - You have given written permission to take part and for your health information to be used - You are generally able to care for yourself and carry out some daily activities, even if you cannot do heavy physical...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been referred for a specific type of ultrasound-guided biopsy procedure (called EUS-FNA) to examine a fluid-filled sac (cyst) on your pancreas, and surgery is being considered - Your pancreatic cyst measures at least 2.0 cm (about t...

**Who might be able to join this trial:** - You have been confirmed by a lab test (from a tissue or fluid sample) to have a type of pancreatic cancer called adenocarcinoma. - Your cancer is located only in the pancreas and may be removable by surgery. - You are 18 years of age or older. - You are generally healthy and...

**Who might be able to join this trial:** - People aged 18 years or older - People who have had surgery that completely removed the cancer with no cancer cells left at the edges (called R0 resection) - People who have not previously been treated with a chemotherapy drug called gemcitabine for any cancer - People who a...

**Who might be able to join this trial:** - People aged 18 or older who are able to give written consent to participate - People diagnosed with localised pancreatic cancer where surgery (such as removal of part or all of the pancreas) is possible - People diagnosed with localised pancreatic cancer that cannot be opera...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma or undifferentiated carcinoma of the pancreas, confirmed through a tissue or cell sample - People who have at least one tumour that can be measured using standard imaging guidelines (RECIST v1.1) - People wh...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with advanced pancreatic cancer or liver cancer (hepatocellular carcinoma) that has not spread far beyond its original location, and your doctors are considering treating it with a combination of chemotherapy and radiation,...

Who might be able to join this trial: - People who have been newly diagnosed with pancreatic cancer, bile duct cancer, or gallbladder cancer and are currently receiving some form of treatment, such as surgery, chemotherapy, or palliative care. - People who are 18 years of age or older. Who may not be able to join: - P...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a lab test on tissue or fluid samples. - People whose cancer has not spread to distant parts of the body (no metastatic disease). - People whose scans clearly s...

Who might be able to join this trial: - Adults who have been diagnosed with pancreatic cancer or a type of pancreatic cyst called IPMN (Intraductal Papillary Mucinous Neoplasm) and are scheduled for surgery soon - Adults who are having surgery to remove part of the pancreas because of a suspected IPMN - People who are...

Who might be able to join this trial: - Adults aged between 18 and 75 years old - People who have been diagnosed with pancreatic cancer, bile duct cancer, or cancer of the ampulla (a small opening where the bile and pancreatic ducts meet the small intestine), and who have had a surgical procedure called a pancreatoduod...

**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer), either confirmed through a tissue sample or diagnosed by a specialist medical team without a tissue sample - People whose medical team...

Who might be able to join this trial: - People who have a mass in the pancreas and a suspected diagnosis of pancreatic ductal adenocarcinoma (a type of pancreatic cancer) that requires either an endoscopic ultrasound with a needle biopsy or surgery - People who are 18 years of age or older - People who have not yet rec...

Who might be able to join this trial: - People who have fluid-filled sacs (cysts) in the pancreas that meet specific concern levels known as "Fukuoka worrisome" or "Fukuoka high-risk" criteria (confirm with trial site for what this means in your case) - People who are suspected to have a type of cyst in the pancreas th...

**Who might be able to join this trial:** - People who have been diagnosed with one of the following cancer types, confirmed by laboratory tissue testing: pancreatic cancer, certain virus-linked cancers (such as cervical, head and neck, nasal, or nasopharyngeal cancers), Kaposi's sarcoma, non-small cell lung cancer, s...

**Who might be able to join this trial:** - People who are at least 50 years old. - People diagnosed with diabetes within the past 12 months, where there is a record of previously normal blood sugar levels within the past 2 years, and whose HbA1c (a blood sugar level measure) is 6.5% or above. - People diagnosed with...

**Who might be able to join this trial:** - People who have signed a written consent form agreeing to take part in the study and allowing their personal health information to be shared. - People who have been confirmed through a tissue or cell sample test to have adenocarcinoma of the pancreas (a specific type of panc...

**Who might be able to join this trial:** - People aged 18 or older who are able to understand and willing to sign a consent form - People with a confirmed diagnosis of pancreatic adenocarcinoma (a specific type of pancreatic cancer) that is classified as resectable, borderline resectable, locally advanced, or metasta...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer (including adenocarcinoma or other types of malignant pancreatic tumors) confirmed through tissue or cell testing - People who have at least one tumor that can be measured using medical imaging - People whose cancer was initia...

**Who might be able to join this trial:** - People who have been diagnosed with Von Hippel-Lindau (VHL) disease, either through genetic testing that found a specific gene change, or through clinical diagnosis based on symptoms and medical history. - People who have at least one sign of VHL affecting the pancreas (a gl...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) that has been confirmed by laboratory testing and has not spread to distant parts of the body - People who have had surgery to fully remove their pancreatic cancer - People who have...

Who might be able to join this trial: - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed by tissue or cell testing, or who are strongly suspected of having this condition before surgery aimed at curing it - People who have not yet received any treatme...

**Who might be able to join this trial:** - People who are over 18 years of age - People being treated for pancreatic adenocarcinoma (a type of pancreatic cancer) - People whose medical team considers them suitable for at least one surgery and chemotherapy - People who are willing and able to give their informed consen...

**Who might be able to join this trial:** - People who have been diagnosed with advanced pancreatic cancer that has spread or come back, confirmed by a laboratory test, and who have already received standard chemotherapy (and surgery, if the cancer returned after an operation). - People whose tumour has a specific gen...

Who might be able to join this trial: - Adults aged 18 or older. - People diagnosed with stage IV pancreatic cancer or stage IV breast cancer (including those whose cancer responded completely to prior chemotherapy). - People whose doctor estimates they have at least 6 months life expectancy. - People whose overall hea...

Who might be able to join this trial: - People who are 18 years of age or older, of any gender - People who have been diagnosed with a specific type of pancreatic cancer (adenocarcinoma or adenosquamous carcinoma) that doctors consider possibly removable by surgery, either upfront or after initial chemotherapy and/or r...

**Who might be able to join this trial:** - People who are aged between 50 and 75 years old. - People who have had a CT scan, MRI, or endoscopic ultrasound (a camera procedure to look inside the body) within the past 6 months that found one or more fluid-filled sacs (cysts) on the pancreas, each measuring at least 1 cm...

**Who might be able to join this trial:** - You have been seen at a GI clinic, surgery department, or endoscopy unit and doctors suspect or have confirmed that you have a problem with your pancreas (such as a cyst, growth, cancer, or inflammation), based on your symptoms, scans, or blood tests. - You have not yet had a...

Who might be able to join this trial: - Adults who have been diagnosed with locally advanced pancreatic cancer (confirmed by a biopsy) and whose treating oncologist has determined they are suitable for combination chemotherapy. Who may not be able to join: - People who are pregnant. - People whose pancreatic cancer ha...

Who might be able to join this trial: - Adults aged 30 years or older - People who have been diagnosed with at least one pancreatic cyst through imaging (such as a scan) or a camera procedure, regardless of whether they are currently being treated for it - People with no history of pancreatic cancer - People who can sp...

**Who might be able to join this trial:** - You have been diagnosed (confirmed by a lab test) with a specific type of cancer in or near the digestive system, such as pancreatic cancer, stomach/esophagus cancer, bile duct cancer, gallbladder cancer, or a related type, that has spread locally or to other parts of the bo...

Who might be able to join this trial: - People who have a mass in the pancreas and are suspected of having a type of pancreatic cancer called pancreatic ductal adenocarcinoma, and who need a procedure where a doctor uses an ultrasound probe and a needle (passed through a small camera into the digestive tract) to take a...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer) confirmed by a biopsy - People whose cancer was not able to be removed by surgery at the time of diagnosis, either because it has spread to nearby areas or to other parts of...

**Who might be able to join this trial:** *For people with lung cancer:* - People diagnosed with locally advanced non-small cell lung cancer (stage I–III) who are not able to have surgery, or those with stage IIIa who are planned for a combination of chemotherapy, radiation, and then surgery - People aged 18 years or...

**Who might be able to join this trial:** - People aged between 18 and 75 years old at the time of signing the consent form. - People whose pancreatic cancer has been confirmed through a tissue or cell sample (biopsy or similar test). - People who are largely able to carry out daily activities with little or no limita...

**Who might be able to join this trial:** - People being treated at Reims University Hospital for a pancreatic tumour that can be surgically removed, or that may become removable after treatment, with or without pre-surgery chemotherapy - People aged 18 or older - People who have read and signed the trial's consent for...

Who might be able to join this trial: **Healthy Volunteers (a small group of 5 people):** - You are 19 years of age or older - You do not have any known major health conditions, including cancer, heart disease, diabetes, high blood pressure, high cholesterol, stroke, breathing problems, or arthritis - People of all ra...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma or adeno-squamous carcinoma (specific types of pancreatic cancer) that has spread to the liver, confirmed through tissue or cell testing. - People whose cancer has spread to other parts of the body as well, as lon...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) confirmed by a tissue or cell sample test - People whose scans show no signs that the cancer has spread to other parts of the body - People aged 18 or older - People who are currently re...

**Who might be able to join this trial:** **Colorectal cancer (CRC) group:** - People who have been diagnosed with colorectal cancer that has spread to the liver (confirmed by tissue or cell testing), classified as stage IV - People for whom surgery and/or chemotherapy has been recommended as a treatment option - Peop...

**Who might be able to join this trial:** - People who are 18 years of age or older - People with a confirmed diagnosis of pancreatic adenocarcinoma (a specific type of pancreatic cancer) that has spread or cannot be surgically removed, and where at least one measurable tumour or affected lymph node is visible on scan...

**Who might be able to join this trial:** - People who have been diagnosed with an advanced or spreading cancer that has either stopped responding to existing treatments, has continued to grow despite standard treatment, or where existing treatments have caused intolerable side effects. - People whose cancer has tumors...

**Who might be able to join this trial:** - You are suspected of having pancreatic cancer and are scheduled for a procedure (endoscopy) to take a tissue sample for diagnosis. - You are willing to have a tissue sample taken during an endoscopic procedure for research purposes, or you can provide a previously collected...

**Who might be able to join this trial:** - People aged 18 to 80 years old - People whose general health and ability to carry out daily activities meets a certain standard, as measured by a medical scoring tool called the ECOG scale (score of 2 or below, meaning the person is able to be up and about for at least half...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of giving consent - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scale (ECOG score of 0–2) - People who have been diagnosed with p...

**Who might be able to join this trial:** - People who are already participating in the PACAP cohort study and have previously given written consent to be included in future randomised studies - People whose pancreatic cancer has come back only in the area where it was originally removed (called a local recurrence), wi...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic cancer confirmed through a tissue or cell sample test - People whose cancer has been classified as "borderline resectable" according to a specific international medical definition from 2017 (confirm with trial site) - People who...

**Who might be able to join this trial:** - You are between 20 and 80 years old - You have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed by a tissue or cell sample - You have had surgery to remove the cancer (either fully or at the edges) at least 2 weeks ago but...

Who might be able to join this trial: - People who have been diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer) and had it confirmed through a biopsy (tissue sample test) - People who have a permanent home address - People who agree to take part in the study - People whose CT scan results are...

**Who might be able to join this trial:** - People with a strong family history of pancreatic cancer — for example, having at least two close blood relatives (such as a parent or sibling) on the same side of the family who had pancreatic cancer, where at least one of those relatives is a parent, sibling, or child of t...

**Who might be able to join this trial:** - People who are considered high risk for developing pancreatic cancer (falling into one of three groups below) and are already taking part in a pancreatic monitoring programme, AND who have an abnormality found on a pancreas scan (such as a pancreatic cyst). - **High Risk Gr...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People diagnosed with locally advanced or metastatic pancreatic cancer that cannot be treated with surgery (excluding a specific type called islet cell carcinoma), confirmed by a tissue or cell sample - People who have not had standard can...

**Who might be able to join this trial:** - People who have a pancreatic neuroendocrine tumour (a type of slow-growing pancreatic tumour) measuring between 2 cm and 3 cm in size. - People who have a tumour between 1.0 cm and 2.0 cm that has been growing at a moderate rate (2–4 mm per year) based on a series of follow-...

**Who might be able to join this trial:** - People who have been diagnosed with a well-differentiated pancreatic neuroendocrine tumour (a specific, slower-growing type of pancreatic tumour) that was surgically removed between 14 and 120 days before joining the trial - People who had a scan within the past 90 days show...

**Who might be able to join this trial:** - People who have been newly diagnosed with exocrine pancreatic cancer, where either a tissue sample or imaging scan suggests it is adenocarcinoma (a specific type of pancreatic cancer) - People whose cancer is classified as resectable or borderline resectable (meaning surgery...

**Who might be able to join this trial:** **Group A (current patients):** - Adults aged 18 or older who have lesions (abnormal growths) in the liver - People with up to five liver tumors that cannot be surgically removed, where at least one of the following applies: the tumor is at least 3 cm in size; the tumor is loc...

**Who might be able to join this trial:** **Group I (no strong family history of pancreatic cancer):** - People who have a documented harmful or likely harmful genetic mutation in one of these genes: BRCA1, BRCA2, ATM, or PALB2 - People who do not have a close family history of pancreatic cancer — meaning no first-deg...

**Who might be able to join this trial:** - People aged 18 to 75 at the time of signing the consent form - People with pancreatic cancer that has spread to other parts of the body (metastatic), confirmed by tissue or cell testing - People who have at least one measurable area of cancer spread, detectable by a chest, a...

**Who might be able to join this trial:** - People who are able to understand the study information and agree to take part voluntarily. - People who are willing and able to attend all required study visits and follow the study procedures. - Adults aged 18 or older. - People whose cancer has not significantly affected...

**Who might be able to join this trial:** - People who have been confirmed by a local pathologist to have a type of pancreatic cancer called adenocarcinoma, located in any part of the pancreas - People whose cancer is classified as "borderline resectable" (meaning surgery is possible but complex), confirmed by a team...

**Who might be able to join this trial:** - People who are able to understand and willing to sign a written consent form - People who have been diagnosed with pancreatic cancer - People who are currently receiving, or who have received within the last 12 weeks, cancer treatment such as surgery, radiation, chemotherapy...

**Who might be able to join this trial:** - People who have been diagnosed with a condition called hyperinsulinemic hypoglycemia (where the body produces too much insulin, causing dangerously low blood sugar levels), confirmed through blood tests or specific medical tests. - People for whom standard medications used to...

**Who might be able to join this trial:** - Adults between 18 and 75 years of age - People who have been diagnosed with primary, relapsed, or spread (metastatic) cancer of the liver, bile ducts, or pancreas, confirmed by a tissue sample - People whose doctors estimate they have a life expectancy of more than 3 months...

Who might be able to join this trial: - Adults aged 18 years or older - People who are able to give their voluntary agreement to participate in writing Who may not be able to join: - People whose symptoms would make an internal examination of the lower bowel unsafe or unsuitable — for example, those with a painful tea...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with a specific type of cancer in the head of the pancreas (pancreatic adenocarcinoma, duodenal adenocarcinoma, ampullary adenocarcinoma, or a cyst-related cancer called IPMN with adenocarcinoma), confirmed by a spec...

Who might be able to join this trial: - People who had surgery to remove part or all of their pancreas or liver at Methodist Dallas Medical Center (MDMC) between January 2006 and December 2020 - People who were 18 years old or older at the time of their surgery Who may not be able to join: - People who did not have su...

**Who might be able to join this trial:** - You have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample. - You are planned to start a first-line chemotherapy treatment called FOLFIRINOX (meaning you have not yet had chemotherapy for your cur...

**Who might be able to join this trial:** - People who are over 18 years old - People who have pancreatic cancer that has been classified as resectable, borderline resectable, or locally advanced, confirmed through CT scan, ultrasound, or other imaging - People who are in reasonably good general health, as measured by...

Who might be able to join this trial: - People who have been recommended surgery for a tumor or cyst in the pancreas or the area around it (called the periampullary region) - People whose relevant medical information is available in electronic health records - People who have given their informed consent to participate...

Who might be able to join this trial: - People who have a medical reason that requires them to have an endoscopic procedure (a procedure where a small camera is used to look inside the body) Who may not be able to join: - People who have not given their formal written agreement to take part in the trial - People under...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic cancer, confirmed through a tissue or cell sample — or, in some cases, through scan findings combined with a raised CA 19-9 blood marker (confirm with trial site) - People whose cancer cannot be fully removed by surgery, either...

Who might be able to join this trial: - People aged 5 to 85 years old - People who, after review by a medical team, are able to have standard surgery, and whose surgical tissue sample confirms pancreatic cancer or another pancreatic condition - People who have not taken antibiotics or consumed yogurt containing probiot...

Who might be able to join this trial: - People who are 18 years of age or older - People who are willing to sign a consent form agreeing to take part in the trial - People who have had a CT scan, MRI, or endoscopic ultrasound (a camera procedure to look inside the body) showing that a pancreatic lesion is locally advan...

Who might be able to join this trial: - People who have given their signed consent to participate - People who have been confirmed through tissue testing to have pancreatic ductal adenocarcinoma (a type of pancreatic cancer) and are planned to start standard first-line treatment, OR people suspected of having locally a...

**Who might be able to join this trial:** - People who have been fully informed about the study and have voluntarily agreed to take part by signing a consent form - People whose pancreatic cancer has been confirmed by laboratory tissue or cell testing, and whose cancer cannot be surgically removed, has spread to nearb...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have been diagnosed with a pancreatic neuroendocrine tumor (a specific type of pancreatic tumor) confirmed by a tissue sample taken during an internal ultrasound procedure, and whose tumor is classified as a lower-grade t...

**Who might be able to join this trial:** - People who are scheduled to have a surgical procedure called a pancreaticoduodenectomy (removal of part of the pancreas and surrounding structures) or total pancreatectomy (removal of the entire pancreas), for any medical reason - People who are scheduled to have a distal pan...

**Who might be able to join this trial:** - People who have had surgery as part of their treatment. **Who may not be able to join:** - People who lost more than 10% of their body weight in the 6 months before their surgery. - People who have cancer that has spread to distant parts of the body (known as distant metasta...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) that cannot be removed by surgery and has either spread to nearby areas or to other parts of the body, confirmed by laboratory testing of tissue or cell samples - Peop...

**Who might be able to join this trial:** - You are scheduled to have planned (non-emergency) surgery to remove part or all of the pancreas due to pancreatic cancer **Who may not be able to join:** - You have previously had surgery for cancer - You have lost more than 10% of your body weight in the 6 months before sur...

Who might be able to join this trial: - People who have signed a written consent form before any study procedures begin (or whose legal representative has signed on their behalf) - People who have a solid tumour that has been confirmed by lab testing, is locally advanced or has spread to other parts of the body, and ca...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma), confirmed by a biopsy, and your doctors believe surgery to remove the cancer may be possible - You are willing to have small tissue samples (biopsies) ta...

Who might be able to join this trial: - People aged 18 years or older - People diagnosed with borderline resectable or locally advanced pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), as defined by standard oncology guidelines (confirm with trial site) - People whose cancer diagnosis has been c...

**Who might be able to join this trial:** - People aged 18 or older - People who have at least one fluid-filled sac (cyst) in the pancreas, measuring 5mm or larger, that has been identified by a scan (CT, MRI, or endoscopic ultrasound) as a possible IPMN or MCN (specific types of pancreatic cysts) — or people who are g...

Who might be able to join this trial: - You are at least 18 years old - You have been diagnosed with pancreatic cancer that has spread to other parts of the body, and you have not yet received any treatment for it (meaning you are eligible for your first round of treatment) - You are able to give verbal agreement to ta...

**Who might be able to join this trial:** - People who have a confirmed or suspected pancreatic tumour that has grown into surrounding tissue - People whose tumour has been classified as either "borderline resectable" (potentially removable by surgery) or "locally advanced" (has spread nearby but not to distant parts o...

**Who might be able to join this trial:** - People diagnosed with pancreatic cancer that has not spread to other parts of the body, who are about to start chemotherapy before surgery - People aged 18 or older - People who speak English or Spanish - People who are willing and able to sign a consent form agreeing to take...

Who might be able to join this trial: - People who are willing to sign a consent form allowing their personal health information to be used by the Levine Cancer Institute and Atrium Health - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with pancreatic...

**Who might be able to join this trial:** - Your cancer must be an advanced solid tumor that has been confirmed by a lab test (biopsy), with a specific genetic change (mutation) in a gene called KRAS G12 or RAS, found through DNA testing — or, for one part of the trial, a pancreatic cancer without a RAS mutation - You...

Who might be able to join this trial: - People who are over 18 years old, of any gender - People who have pancreatic cancer (a specific type called PDAC) that has spread or is at an advanced stage - People who have received no more than one previous chemotherapy treatment for their advanced or spread cancer (radiation...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer (stage I–IV) or colorectal cancer (stage III–IV) through a laboratory test on tissue samples, and who are planning to receive treatment. - People who have previously had surgery, radiation therapy, or chemotherapy that did not...

Who might be able to join this trial: - People aged 18 or older (children are not included in this trial because safety information for that age group is not yet available). - People whose general health and ability to carry out daily activities meets a minimum functional level, as assessed by their doctor (confirm wit...

**Who might be able to join this trial:** *For the dose escalation and combination treatment parts of the trial:* - People who are 18 years of age or older - People who have been diagnosed with a specific type of ovarian cancer (high-grade serous or endometrioid epithelial ovarian cancer), triple-negative breast canc...

Who might be able to join this trial: - People who are able to understand and sign a written consent form agreeing to take part in the study - People who have been diagnosed with a specific type of pancreatic cancer called ductal adenocarcinoma, confirmed by a tissue or cell sample test - People whose cancer has not sp...

**Who might be able to join this trial:** - People who have pancreatic cancer where the tumour has been assessed by a specialist medical team as removable by surgery, or close to being removable by surgery - People whose CT scan shows no cancer spread to the liver - People who are at least 18 years old and are able to...

Who might be able to join this trial: - People who have at least one tumour that can be measured using standard imaging guidelines - For Part A: People who have been confirmed (by lab testing of tissue or cells) to have an advanced or spreading solid tumour that cannot be surgically removed, and who have already tried...

Who might be able to join this trial: - People who have been clinically diagnosed with IPMN (a type of pancreatic cyst condition) - People who do not have any other type of cancer or malignant tumour - People who are willing to sign a consent form agreeing to take part in the trial Who may not be able to join: - Peopl...

**Who might be able to join this trial:** - People who are over 18 years old. - People who have been diagnosed with an advanced solid tumour (confirmed by lab testing of tissue or cells) that has not responded to standard treatments, where standard treatments are not tolerated, or where no standard treatment exists —...

**Who might be able to join this trial:** - Adults aged 18 years or older who weigh more than 30 kg (about 66 pounds) - People with an expected survival of at least 12 weeks - People who have been diagnosed with advanced pancreatic cancer, liver cancer (hepatocellular carcinoma), or bile duct/gallbladder cancer (bilia...

**Who might be able to join this trial:** - A diagnosis of pancreatic adenocarcinoma (a specific type of pancreatic cancer) that has been confirmed by a tissue sample — other types of pancreatic cancer are not eligible - Cancer that has been staged as T1–T3, N0–N2, M0, meaning it has not spread to distant parts of the...

**Who might be able to join this trial:** - People who carry known gene changes (mutations) that raise their risk of developing cancer - People with a personal or family history that suggests a higher-than-average cancer risk, even if genetic testing came back negative or has not been done - People who have been clini...

**Who might be able to join this trial:** - You are willing and able to sign a consent form before any trial-related procedures begin. - You are willing and able to follow the trial schedule, including all visits, treatments, and check-ups. - Your pancreatic cancer has been confirmed by a lab test (biopsy or cell samp...

Who might be able to join this trial: - People with a confirmed diagnosis of lymphoma, colorectal cancer, or pancreatic cancer - People whose treatment plan includes surgery, chemotherapy, or radiation therapy - People who have agreed to take part by signing an informed consent form Who may not be able to join: - Peop...

**Who might be able to join this trial:** - Adults over 18 years old who have been diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer), either confirmed by a tissue sample (biopsy) or by imaging scans such as CT, MRI, or PET, and have not yet received any treatment for it - People whose cancer...

Who might be able to join this trial: - People aged 18 years or older. - People who have been diagnosed with locally advanced pancreatic cancer (cancer that has grown into nearby blood vessels but has not spread to other parts of the body), confirmed by a pathology test. - People whose cancer has not grown or spread (a...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People whose ability to carry out daily activities falls within a certain range, meaning they are fully active or have some limitations but are still able to care for themselves (confirm with trial site) - People who have been diagnosed wi...

**Who might be able to join this trial:** - People aged 19 to 80 years old - People with a good general health and activity level, as measured by a standard medical scoring tool called the ECOG scale (score of 0 or 1), meaning they are fully active or have only minor limitations in physical activity - People whose pan...

Who might be able to join this trial: **Cancer Arm (people with a recent cancer diagnosis):** - People aged 40 to 75 years old. - People who are able to sign a written consent form. - People who have not yet received any cancer treatment, and either have a confirmed cancer diagnosis made within the past 42 days, or ar...

Who might be able to join this trial: - People who have had surgery and received a confirmed medical diagnosis of a solitary pulmonary nodule (a small spot found on the lung) based on the surgical findings - People who have given their agreement to take part in the trial - People whose questionnaire responses are compl...

**Who might be able to join this trial:** *People with pancreatic cancer (12 spots):* - Adults aged 18 or older who have recently been diagnosed with pancreatic cancer (whether it has spread or not) and who have been on tube feeding or IV nutrition for 14 days or less *Within that group, people with cachexia (signifi...

**Who might be able to join this trial:** - People aged 18 or older who are male, or female and neither pregnant nor breastfeeding at the time of signing consent forms. - People who are well enough to carry out most daily activities, as measured by a standard health performance scale (a score of 70% or higher on the K...

Who might be able to join this trial: - People who are 18 years of age or older - People who meet the criteria for one of the specific groups being studied in this trial (confirm with trial site) - People who are able to understand and agree to participate in the study - People who are able to provide a blood sample W...

**Who might be able to join this trial:** - You are between 18 and 75 years old (inclusive) - Your doctor expects you to live for at least 3 more months - You have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample - Your cancer is locally advance...

**Who might be able to join this trial:** - People who have been diagnosed with locally advanced pancreatic cancer (a type of cancer that has not spread to distant parts of the body), confirmed by laboratory testing of tissue or cell samples, as defined by National Comprehensive Cancer Network guidelines. - People who...

Who might be able to join this trial: - People who have been diagnosed (through a tissue or cell sample) with pancreatic neuroendocrine tumors (PNETs) that have spread or cannot be surgically removed, of any grade (1, 2, or 3) - People whose tumors show up on a special type of scan (SSR PET/CT) that confirms the tumor...

**Who might be able to join this trial:** - Adults who are 18 years of age or older at the time of signing the consent form - People who identify themselves as African American or Non-Hispanic White - People who are visiting a GI (digestive health) clinic, surgery department, or endoscopy unit at a participating Florid...

Who might be able to join this trial: - You must be 18 years of age or older - You either have been diagnosed with pancreatic cancer at any stage, or your doctor suspects you may have pancreatic cancer and is planning to investigate it further - You must be willing and able to agree to take part by signing a consent fo...

**Who might be able to join this trial:** - You are scheduled to have a planned surgery to remove part of your pancreas (the left side), with or without also having your spleen removed - You are 18 years old or older - You are able to understand the study information and are willing to sign a consent form agreeing to t...

Who might be able to join this trial: - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed through a tissue biopsy. - People who have had a CT scan or MRI showing the pancreatic cancer measures at least 1 cm at its widest point. - People whose general h...

Who might be able to join this trial: - You must already be registered on a specific Italian registry for people with a family history of pancreatic cancer (called the IRFARPC registry). - You must have a known family connection to pancreatic cancer, as defined by specific guidelines used by that registry. - You must b...

**Who might be able to join this trial:** - People of any gender aged 18 or older - For the VAPOR 1 part of the trial: people who have been diagnosed with pancreatic cancer (confirmed by tissue testing), people who have recently developed diabetes or have chronic pancreatitis, or people with general digestive symptoms...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People who have had imaging tests (such as ultrasound, CT scan, or MRI) that identified a cyst or suspected cystic tumour on the pancreas - People who have agreed to undergo surgical removal of the pancreatic cystic tumour - People (or...

**Who might be able to join this trial:** - People who have been diagnosed with, or are suspected to have, a type of pancreatic cancer called pancreatic adenocarcinoma. - People who are currently a patient at the University of Pennsylvania. - People who are able to understand and agree to take part in the study (give i...

**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with a pancreatic neuroendocrine neoplasm (a type of tumour in the pancreas), confirmed by a tissue sample taken from any location in the body, such as the original tumour site or a spread (metastatic) site. - Both newly diagnos...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are healthy enough to undergo a planned surgical removal of part of the pancreas, or to receive palliative (comfort-focused) treatment - People who have been diagnosed with a specific type of pancreatic cancer called pancre...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) that is either borderline removable by surgery, too advanced for surgery, or where surgery is not safe for medical reasons, confirmed by a tissue or cell sample. - People who are general...

**Who might be able to join this trial:** - People who have been newly diagnosed with metastatic pancreatic adenocarcinoma (a specific type of pancreatic cancer that has spread to other parts of the body) that has been confirmed by biopsy and has not yet been treated. - People who have at least one measurable tumor th...

**Who might be able to join this trial:** - People who have advanced cancer where the tumour cells carry a protein called Mesothelin. - People who are expected to live for more than 12 weeks. - People whose heart, lungs, liver, kidneys, and blood are all functioning well enough to meet the trial's requirements. - Peop...

Who might be able to join this trial: - People who are scheduled to have a planned (non-emergency) surgical procedure called a pancreatoduodenectomy (a major operation involving the pancreas and nearby organs), and who have a higher chance of having bacteria in their bile — either because they had a tube placed before...

"Who might be able to join this trial: **Sub-study 1:** - You are suspected of having pancreatic cancer (at an early to intermediate stage, not yet spread widely) and are scheduled for surgery to remove part of the pancreas, with or without receiving chemotherapy beforehand. **Sub-study 2:** - You have been diagnosed...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic cancer through a tissue sample (biopsy), where the tumour is either on the borderline of being removable by surgery, or has grown into nearby areas but has not spread to distant parts of the body. - People for whom doctors have p...

**Who might be able to join this trial:** - People who have given written consent to take part in the study and its related tests. - People who have been diagnosed with pancreatic cancer (PDAC) that has spread to other parts of the body, confirmed by a tissue or cell sample. - People who have not yet received any trea...

**Who might be able to join this trial:** - People who fully understand the study and are willing to sign a consent form agreeing to take part. - Adults aged 18 or older at the time of signing the consent form. - People who have been diagnosed with a specific type of pancreatic cancer (pancreatic ductal adenocarcinoma...

Who might be able to join this trial: - People who have been diagnosed (confirmed by biopsy) with advanced or spread (metastatic) solid tumours of specific cancer types: breast cancer (all subtypes), non-small cell lung cancer, gastrointestinal cancers including pancreatic cancer, bladder cancer, kidney cancer, melanom...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample - People whose pancreatic cancer cannot be surgically removed, either because it has spread to nearby areas or...

**Who might be able to join this trial:** - People who are suspected of having or have been diagnosed with a tumour near the area where the pancreas meets the small intestine (called a periampullary tumour), and for whom a specific type of pancreatic surgery (called a Whipple procedure or pylorus-preserving pancreatic...

**Who might be able to join this trial:** - You were diagnosed with pancreatic cancer at age 55 or younger. - You are at least 18 years old. - You are willing and able to sign a written consent form to take part in the study. **Who may not be able to join:** - You have a type of pancreatic or nearby tumor that is not...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People whose tissue biopsy results confirm one of three specific types of pancreatic tumour: a non-functional pancreatic neuroendocrine tumour, pancreatic ductal adenocarcinoma, or solid pseudopapillary tumour - People who have not rec...

Who might be able to join this trial: - Adults aged 18 or older who are planned to have surgery to remove part or all of the pancreas, with the goal of curing their condition, at one of the hospitals in the Dutch Pancreatic Cancer Group that performs this type of surgery - People whose surgery may or may not include tr...

Who might be able to join this trial: - People who are able to understand and willingly sign a consent form before any study procedures begin - People aged 18 to 75 years old at the time of signing the consent form - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic can...

**Who might be able to join this trial:** - People aged 18 to 80 years old - People who have been confirmed, through clinical assessment, imaging, and tissue testing, to have Stage IV pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) that has spread to distant parts of the body, with tumours that...

Who might be able to join this trial: - Adults aged 18 years or older - People who are being treated for a pancreatic tumour using a procedure called radiofrequency ablation, which uses heat delivered through a fine needle guided by ultrasound - People whose case has been reviewed and approved for this procedure by a t...

Who might be able to join this trial: - Adults aged 18 or older who have one or more cysts on their pancreas - People who are scheduled to have surgery or a tissue sample taken from a pancreatic cyst - People who are able to understand the study and are willing to sign a consent form - Both English-speaking and non-Eng...

**Who might be able to join this trial:** - People who are willing and able to give written consent to participate - People aged 18 to 75 years old, of any gender - People whose general health and ability to carry out daily activities is rated at a good level (ECOG score of 0 or 1 — confirm with trial site if unsure w...

Who might be able to join this trial: - People who are willing to take part voluntarily, have been fully informed about the study, and have signed a consent form - People aged 18 to 79 years - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed through...

Who might be able to join this trial: - Adults aged 18 or older. - People who have been diagnosed with pancreatic cancer that has been confirmed through laboratory testing of tissue samples. - People who are able to understand and willing to sign a written consent form. Who may not be able to join: - People under the...

**Who might be able to join this trial:** - People who have voluntarily agreed to take part and are willing and able to follow the study's procedures, as judged by the research team - People who are 18 years of age or older at the time of signing the consent form, of any gender - People who have been diagnosed with lo...

**Who might be able to join this trial:** - People who have been diagnosed with metastatic pancreatic cancer, confirmed by a tissue or cell sample analysis. - People whose cancer has been stable (not grown or spread) after receiving at least 8 cycles of a chemotherapy regimen called FOLFIRINOX, based on standard measu...

**Who might be able to join this trial:** - People aged 21 or older - People who have been diagnosed with pancreatic cancer confirmed by a tissue or cell sample - People whose cancer is at an advanced stage and cannot be fully removed by surgery (either locally advanced or spread to other parts of the body) - People w...

Who might be able to join this trial: - People who have been clinically diagnosed with pancreatic cancer on the left side of the pancreas that doctors have determined can be removed with surgery. - People whose tumor measures 4 cm (about 1.5 inches) or less in size on imaging scans. - People whose tumor is located at l...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been diagnosed with a pancreatic cyst (known as a pancreatic cystic neoplasm) confirmed through specific specialist procedures, including fluid testing and/or imaging techniques performed during an endoscopic ultrasound - Peopl...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed by laboratory testing of tissue - People whose cancer has been staged at certain levels — not too advanced — based on the size of the tumor, whether it has...

**Who might be able to join this trial:** - People who have voluntarily agreed to take part and have signed a consent form - People with pancreatic cancer that cannot be removed by surgery, or that has spread locally or to other parts of the body, confirmed by a tissue or cell sample test - People aged between 18 and...

Who might be able to join this trial: - People who are planning to receive radiotherapy (radiation treatment) for either cervical cancer or pancreatic cancer - People who are reasonably able to carry out daily activities with little to no limitation from their illness (this is measured on a standard scale used by docto...

**Who might be able to join this trial:** *For patients with pancreatic cancer (Part A):* - You are 18 years of age or older - You have been diagnosed with pancreatic cancer that has been treated with pre-surgery therapy (neoadjuvant treatment) and you are scheduled to have surgery to remove the tumour - You are able...

**Who might be able to join this trial:** - People who are reasonably well and able to carry out daily activities with little or no limitation (as measured by a standard medical scale called ECOG, scored 0 or 1). - People with a life expectancy of more than 3 months. - People who have been confirmed (through tissue or...

Who might be able to join this trial: - Adults aged 18 or older at the time of joining the study - People whose general health and ability to carry out daily activities is rated as 0 or 1 on a standard oncology scale (meaning fully active or able to do light work) - People diagnosed with a specific type of pancreatic c...

**Who might be able to join this trial:** - People who have a specific genetic mutation called KRAS G12C, confirmed through an approved diagnostic test. - People who have been diagnosed with a locally advanced (cannot be surgically removed) or metastatic solid tumour (cancer that has spread), in any organ except the l...

Who might be able to join this trial: - People who are able to understand the study and are willing to sign a written consent form - People aged 18 to 80 years old - People whose general physical functioning is rated at a level that allows them to carry out daily activities with little to moderate limitation (confirm w...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form. - People aged between 18 and 80 years old. - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard oncology...

**Who might be able to join this trial:** *For people with pancreatic cancer that cannot be removed by surgery:* - You are at least 20 years old at the time of signing the consent form - Your pancreatic cancer has been confirmed by a lab test to be a specific type called adenocarcinoma, diagnosed within the last 60 da...

Who might be able to join this trial: - People who have been diagnosed with metastatic pancreatic cancer (a type of cancer that has spread beyond the pancreas), confirmed by a tissue test. - People who are not able to receive a chemotherapy combination called FOLFIRINOX and are about to start first-line treatment with...

**Who might be able to join this trial:** - People whose general physical condition is rated as fully active or restricted only in physically strenuous activity (this is measured using a standard health performance scale called ECOG, scores 0–1) - People who have been confirmed by tissue testing to have locally advanc...

Who might be able to join this trial: - People who are 18 years of age or older - People who have had tests or treatment for a suspected or confirmed pancreatic condition (either non-cancerous or cancerous) and whose information is already recorded in a Dutch medical database called the PACAP audit, or healthy people w...

Who might be able to join this trial: - You must be 18 years of age or older - You have been recommended for surgery with the goal of curing pancreatic or periampullary cancer (a type of cancer near the pancreas) - You are willing and able to sign a consent form agreeing to take part Who may not be able to join: - You...

Who might be able to join this trial: - People who have been diagnosed with either advanced (stage IV) or inoperable non-small cell lung cancer, pancreatic adenocarcinoma (a type of pancreatic cancer), or colorectal cancer — a cachexia (muscle-wasting) diagnosis is not required to be considered. - People who are about...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed through laboratory testing of tissue or cell samples. - People whose pancreatic cancer is advanced — meaning it cannot be surgically removed or has spread to other...

Who might be able to join this trial: - People who have been diagnosed with advanced, inoperable, or metastatic pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue sample from the pancreas or another affected area. - People whose cancer can be measured on scans, according to standard...

Who might be able to join this trial: - People who are scheduled to have an open surgical procedure on the pancreas (either removing the head of the pancreas or the tail/body of the pancreas) for any medical reason - People who are 18 years of age or older - People who are able to understand what the trial involves and...

**Who might be able to join this trial:** - People aged 18 to 75 years old, both male and female, who are willing to give written consent to participate. - People who have been diagnosed with pancreatic cancer that cannot be removed by surgery and has either spread to nearby areas or to other parts of the body, confirm...

Who might be able to join this trial: - You are having surgery to remove a specific type of pancreatic tumor called a non-functioning pancreatic neuroendocrine tumor (a type of slow-growing tumor in the pancreas that does not produce excess hormones) - You are 18 years old or older - You have given your written agreeme...

**Who might be able to join this trial:** - People who carry a harmful gene change in *STK11* and are aged 30 or older - People who carry a harmful gene change in *CDKN2A* and are aged 40 or older — or aged 10 years younger than the earliest pancreatic cancer diagnosis in their family, whichever age comes first - Peop...

**Who might be able to join this trial:** - People who have a mass (lump or growth) in the pancreas that has been examined using a procedure called endoscopic ultrasound (a camera with sound waves), which may have included taking a small tissue or fluid sample - People who have a mass in the pancreas that has been exam...

Who might be able to join this trial: - People aged 19 years or older who have been diagnosed with pancreatic or bile duct cancer that cannot be surgically removed, and whose doctor has planned for them to receive a specific combination chemotherapy treatment called nal-IRI/5-FU/LV Who may not be able to join: - Peopl...

**Who might be able to join this trial:** *Cancer Group:* - You are between 40 and 75 years old on the day you sign up for the study - You are able to read and sign a consent form agreeing to take part - You have been diagnosed with liver, bile duct, or pancreatic cancer, confirmed by a medical test - You have not had...

**Who might be able to join this trial:** - You have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma) that is either "borderline resectable" (possibly removable by surgery) or "locally advanced" (spread nearby but not to distant parts of the body), and surgery is not expected to require re...

Who might be able to join this trial: - You must be 18 years of age or older - You have been diagnosed with pancreatic cancer that has been confirmed through a tissue or cell sample (biopsy), and your doctors have planned for you to have surgery either straight away or after chemotherapy treatment first - Women who cou...

**Who might be able to join this trial:** - You have suspected pancreatic cancer that doctors believe can be removed with surgery - You are being considered for surgery with the goal of curing the cancer - You are willing and able to sign a consent form agreeing to take part - You are at least 18 years old - If you ar...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with pancreatic cancer Who may not be able to join: - Children and anyone under the age of 18 are not eligible to register - People who are unable to give their own informed consent to participate are not eligible to...

Who might be able to join this trial: - People who are able to give signed consent and are willing and able to follow the study requirements. - People who are 18 years of age or older. - People who have been newly diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed by a pat...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form - People aged 18 to 80 years old - People whose general physical ability and daily functioning falls within an acceptable range, as measured by a standard oncology scale (confirm with t...

Who might be able to join this trial: - People who are 18 years of age or older - People who are able to read, understand, and sign a consent form agreeing to take part in the trial - People who meet the trial's specific definition of being a "High-Risk Individual" (confirm with trial site for exact details) Who may n...

**Who might be able to join this trial:** - People aged between 18 and 75 years old - People with a good general health and activity level (rated 0 or 1 on a standard medical scale called the ECOG scale, meaning largely able to carry out normal daily activities) - People whose doctors expect them to live for at least 1...

**Who might be able to join this trial:** - People who are willing and able to give written consent to take part and to allow their personal health information to be shared as part of the study. - People who are 18 years of age or older at the time of giving consent. - People who have a relatively good level of physic...

**Who might be able to join this trial:** **Criteria that apply to all participants:** - A BRAF gene fusion or rearrangement has been detected through an approved genetic test, including blood-based tests. - The cancer cannot be fully removed by surgery, or it has come back after previous treatment. - Any brain, spin...

**Who might be able to join this trial:** *For "exceptional survivors" (people who lived much longer than expected with their cancer):* - People who were 18 years old or older when they were diagnosed - People diagnosed with one of three specific cancers in an advanced (spread) stage: pancreatic ductal adenocarcinoma...

Who might be able to join this trial: - People who have been diagnosed with a non-cancerous or low-risk tumour of the pancreas (such as pancreatic neuroendocrine tumours, solid pseudopapillary tumours, or cystadenomas) that has not spread to nearby blood vessels or other parts of the body - People whose tumour is locat...

Who might be able to join this trial: **Cancer Arm (for people with pancreatic cancer):** - People between 40 and 75 years old - People who have been diagnosed with pancreatic cancer through clinical assessment and/or laboratory/tissue testing - People who have not received, and are not currently receiving, any cancer...

Who might be able to join this trial: - People who are 19 years of age or older. - People who have been recently diagnosed with borderline resectable pancreatic cancer (a form of pancreatic cancer that may be on the border of being removable by surgery) and have not yet received any treatment for it. - People who have...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form. - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer) that has spread to other parts of the body (stage IV), confirmed by a tissue or cell sample. - For the firs...

**Who might be able to join this trial:** - You are able to understand and willing to sign a consent form agreeing to take part in the study. - You are between 18 and 80 years old. - You are able to carry out basic daily activities and care for yourself, with at most some limitations (confirm with trial site). - Your c...

Who might be able to join this trial: - People who are having open pancreaticoduodenectomy (a major surgery to remove part of the pancreas and nearby structures) at the participating hospital during the study period Who may not be able to join: - People who have a known allergy to indocyanine green (a dye used during...

**Who might be able to join this trial:** - People aged 18 or older - People who are largely able to care for themselves day-to-day, with only occasional help from others - People who have a confirmed diagnosis of a neuroendocrine tumor originating in the gastrointestinal tract, pancreas, or chest with specific tumor...

Who might be able to join this trial: - Adults aged over 18 years old - People whose general health and ability to perform daily activities is rated at a reasonably functional level (a medical score called ECOG Performance Status below 2 — confirm with trial site) - People who have a confirmed tissue-based diagnosis of...

**Who might be able to join this trial:** - You are willing to sign a consent form and agree to follow all study requirements for the full duration of the trial - You have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed by a tissue or cell sample - You are older th...

**Who might be able to join this trial:** - People aged 18 or older - People diagnosed with non-small cell lung cancer, colorectal cancer, pancreatic cancer, endometrial cancer, or another type of solid tumour - People whose tumour has a specific genetic change called a KRAS G12D mutation, and who also carry certain i...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People with an advanced solid tumour (such as pancreatic cancer, non-small cell lung cancer, stomach cancer, or colorectal cancer, among others) that has been confirmed by laboratory testing of tissue or cell...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with pancreatic cancer confirmed by a laboratory test (not the neuroendocrine type) - People whose pancreatic tumor has been surgically removed, and who have either received additional treatments such as chemotherapy o...

**Phase I – Dose Escalation (for people with various solid tumours)** Who might be able to join this trial: - People aged 18 to 70 years (male or female) who are able to understand the study risks, are willing to follow the study procedures, and have signed a consent form - People with a solid tumour (confirmed by lab...

**Who might be able to join this trial:** - People who are able to understand and are willing to sign a written consent form - People aged 18 to 80 years old - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scoring system (confi...

Who might be able to join this trial: - People aged 18 to 80 years old. - People who are able to understand the study and are willing to sign a consent form. - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scoring system (called...

Who might be able to join this trial: - You must be willing and able to give your consent to take part in the study - You must be 18 years old or older - You must be able to speak English - You must be able and willing to take part in a one-hour interview - You must have been diagnosed with pancreatic cancer at some po...

**Who might be able to join this trial:** **Based on family history or genetics:** - People aged 50 or older who have two or more relatives on the same side of the family diagnosed with pancreatic cancer, where at least two of those relatives are closely related to each other and at least one is a close blood relative...

Who might be able to join this trial: - People who have a narrowing in their bile duct that doctors have not yet been able to identify the cause of - People for whom a procedure called ERCP (a type of internal examination of the bile ducts) has been recommended by their doctor Who may not be able to join: - People in...

**Who might be able to join this trial:** - People aged 18 to 80 years old who are able to understand and sign a consent form - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample - People whose cancer has been assessed by a doctor...

Who might be able to join this trial: - People who are 18 years of age or older. - People who are willing to sign a consent form approved by an Ethics Committee before any trial-related tests or procedures, and who are willing to follow the trial steps and attend required follow-up visits. - People who have been diagno...

Who might be able to join this trial: - People diagnosed with a specific type of pancreatic cancer called pancreatic ductal adenocarcinoma, confirmed by a specialist medical team. - People aged 18 years or older. - People who are scheduled to have surgery with the goal of fully removing the cancer. Who may not be able...

**Who might be able to join this trial:** - People who have pancreatic cancer or invasive breast cancer, and who are planning to start or have already started cancer treatment - People who report experiencing fatigue at any level - People aged 18 or older at the time of signing consent - People who are able to read and...

**Who might be able to join this trial:** - Men and women who are over 18 years old - People who have a cyst on their pancreas that has been assessed as high risk and needs to be removed by surgery - People who are able to understand and agree to take part in the study by giving informed consent **Who may not be able...

**Who might be able to join this trial:** - People who are willing to take part voluntarily and sign a consent form - People aged 18 to 75 years old - People whose cancer has been confirmed by a tissue or cell sample to be pancreatic ductal adenocarcinoma or adenocarcinoma - People who have not yet received any system...

**Who might be able to join this trial:** - You are 19 years of age or older - You have been diagnosed with a specific type of non-cancerous pancreatic cyst called a mucinous cystic neoplasm (MCN) that can be measured on a scan - Your doctors are not planning surgery to remove the cyst, either because of the cyst's fea...

Who might be able to join this trial: - People who are willing to take part in the study and sign a consent form agreeing to participate. - People who are 18 years of age or older at the time they sign the consent form. - People who have a pancreatic tumour that scans suggest can be fully removed by surgery and that ap...

**Who might be able to join this trial:** - Adults aged 18 or older. - People who have finished surgery and all related treatments around the time of their operation, following standard international guidelines. - People who completed their main cancer treatments (such as surgery, chemotherapy before or after surgery)...

Who might be able to join this trial: - People who are 18 years of age or older - People who are already scheduled to have an internal ultrasound procedure (called EUS) to examine the pancreas, bile duct, lymph nodes in the chest or abdomen, or abnormal growths in the food pipe, stomach, small intestine, or large bowel...

Who might be able to join this trial: - People aged 18 to 75 years old. - People with a good general health and activity level (rated as fully active or restricted only in physically demanding activity, confirmed with trial site). - People who have been diagnosed with a specific type of pancreatic cancer (pancreatic du...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of a specific type of pancreatic cancer called pancreatic ductal adenocarcinoma (PDAC). - People whose main pancreatic tumour can be surgically removed, as shown on a specialised type of CT scan. - People with no more than 3 cancer spots...

**Who might be able to join this trial:** - People who have signed and dated a consent form agreeing to take part in the study - People aged 18 to 75 years old - People who have been confirmed through tissue or cell testing to have pancreatic adenocarcinoma (a specific type of pancreatic cancer) - People who have had...

**Who might be able to join this trial:** - People who have signed a consent form after being fully informed about the trial's purpose, expected effects, and risks - People who have been diagnosed with locally advanced pancreatic adenocarcinoma confirmed by tissue or cell testing, or people who have pancreatic cancer...

**Who might be able to join this trial:** - You are willing to take part voluntarily and able to follow the study requirements after signing a consent form - You are between 18 and 75 years old (inclusive) - You have been diagnosed with pancreatic cancer confirmed by a tissue or cell sample test - Your pancreatic cance...

**Who might be able to join this trial:** - You are between 18 and 80 years old (any gender) - You have been diagnosed with pancreatic cancer confirmed by a tissue sample (biopsy or surgery), and you had surgery to remove the cancer within the last 12 weeks before joining the trial - You did not receive any treatment b...

**Who might be able to join this trial:** - You have been diagnosed with a type of pancreatic cancer called pancreatic ductal adenocarcinoma, confirmed by a biopsy or medical imaging scan - You are 18 years of age or older (any gender) - You are currently receiving a treatment that includes a medication called irinotec...

**Who might be able to join this trial:** - You have been diagnosed with pancreatic cancer (a specific type called adenocarcinoma), confirmed by a tissue or cell sample - You are 18 years of age or older - Your cancer is considered removable by surgery, or "borderline" removable (meaning it may be possible with treatm...

**Who might be able to join this trial:** - People who fully understand what the study involves and have signed the consent form voluntarily. - People who are at least 18 years old at the time of signing the consent form (and no older than 75 for certain groups in this trial). - People who have a life expectancy of at...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender. - People who have been diagnosed with pancreatic adenocarcinoma (a type of pancreatic cancer), either confirmed through a tissue or cell sample, or diagnosed based on scan results combined with a specific blood marker (CA 19-9) above a...

Who might be able to join this trial: - People who are 20 years of age or older at the time of signing the consent form - People who are planned to receive a chemotherapy treatment called FOLFIRINOX after surgery for pancreatic cancer - People who have a good general health and activity level, rated as 0 or 1 on a stan...

Who might be able to join this trial: - People who are willing to give their informed consent to take part in the trial - People who are over 18 years old - People who have pancreatic cancer that has not spread beyond the pancreas and where upfront surgery is planned Who may not be able to join: - People who have anot...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People whose pancreatic cancer (specifically pancreatic ductal adenocarcinoma) has been confirmed through a tissue or cell sample test - People who have not yet received any systemic (whole-body) treatment for locally advanced or meta...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with pancreatic or colon cancer that has been confirmed through a tissue or cell sample (biopsy or lab test) - You have at least one tumor that can be safely biopsied more than once, and you are willing to have a tum...

Who might be able to join this trial: - Adults aged 18 or older who are having a specific type of pancreatic surgery (called open pancreaticoduodenectomy) at the University of Minnesota Who may not be able to join: - People for whom a nerve-blocking procedure would be considered unsafe — for example, those with blood...

Who might be able to join this trial: - People aged 65 or older - People diagnosed with advanced (Stage III or IV) epithelial ovarian cancer or fallopian tube cancer - People diagnosed with pancreatic cancer (Stage I, II, or III) who are receiving chemotherapy before surgery or other main treatment - People diagnosed w...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) through a tissue or cell sample, where the tumour is considered removable by surgery or is on the borderline of being removable — this is assessed using detailed scan...

**Who might be able to join this trial:** - You are willing to take part and have signed a consent form - You are between 18 and 75 years old (male or female) - You have been diagnosed with advanced pancreatic cancer (either spread to other parts of the body or unable to be removed by surgery), and you have at least o...

Who might be able to join this trial: - People aged between 18 and 75 years old - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed by a pathology test - People whose pathology results show at least one of the following: cancer spread to nearby lymph n...

Who might be able to join this trial: - People aged between 18 and 75 years old - People who have been diagnosed with a confirmed cancer of the lung, liver, pancreas, or retroperitoneal area (the space at the back of the abdomen) - People with metastatic cancer where the cancer has spread to only a limited number of si...

**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who are generally active and able to carry out daily activities with little or no limitation (confirmed by a doctor using a standard scale called ECOG, with a score of 0 or 1) - People whose tumor is located in the pancr...

**Who might be able to join this trial:** - People who have been diagnosed (through tissue or cell testing) with an advanced, inoperable, and/or spreading or returning solid tumour cancer. - People who have a good general health and activity level, able to carry out everyday activities with little or no limitation (EC...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of signing the consent form. - People with an advanced or metastatic solid tumour (one that has spread or cannot be cured) that has stopped responding to standard treatments, or where standard treatments are not tolerated. Specific cancer...

Who might be able to join this trial: - People who have been diagnosed with locally advanced pancreatic cancer (cancer confirmed by tissue or cell testing). - People whose pancreatic tumour measures less than 8.0 cm at its widest point at the time of treatment planning (final confirmation depends on meeting certain rad...

**Who might be able to join this trial:** - People who have given written consent to participate, or whose legally authorised representative has done so on their behalf (adults who are unable to consent themselves may be eligible if they have a caregiver who can ensure they take their medication as required). - People...

**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who have been confirmed through a biopsy or cell sample to have pancreatic cancer that started in the ductal lining of the pancreas, and whose cancer has spread to other parts of the body (stage IV) - People who have not...

**Who might be able to join this trial:** - People who have been confirmed by a tissue biopsy to have a slow-growing (Grade 1 or Grade 2) neuroendocrine tumour (NET) that started in the digestive system, pancreas, lungs, or an unknown location in the body. - People whose cancer has spread to other parts of the body, o...

**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed through a tissue or cell sample — a tissue sample is preferred - People whose cancer has been assessed by the tria...

**Who might be able to join this trial:** - You are willing and able to sign a consent form agreeing to take part in the study. - You are between 18 and 75 years old (any gender). - Your doctors expect you to live for at least 3 more months. - You are generally well enough to carry out daily activities with little or...

**Who might be able to join this trial:** - People who have been diagnosed with locally advanced, unresectable, or metastatic pancreatic cancer that is not suitable for curative treatment, confirmed by a tissue biopsy. - People who have received at least one round of chemotherapy (using gemcitabine, 5-fluorouracil/cap...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing consent. - People who are in generally good functional condition, rated 0 or 1 on a standard oncology scale (meaning fully active or able to carry out light work). - People with a confirmed diagnosis of pancreatic adenocarcinoma...

**Who might be able to join this trial:** - People who have voluntarily agreed to sign a consent form to take part in the study - People aged 18 to 70 years old (inclusive), of any gender - People who have been diagnosed with advanced pancreatic cancer or colorectal cancer, whose cancer has not responded to — or who c...

**Who might be able to join this trial:** - People who are willing and able to give written consent and follow all study requirements and procedures. - People who have a confirmed diagnosis of pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), including a related type called adenosquamous carcino...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer confirmed by a laboratory test of tissue or cell samples - People whose general health and ability to carry out daily activities meets a certain minimum level (a doctor will assess this using a standard scale called the ECOG s...

**Who might be able to join this trial:** - People aged 18 or older, of any gender, who are willing and able to follow the study procedures as judged by the research team - People who have been diagnosed with a cancerous tumour of the pancreas through pathology testing, and who had surgery to remove the tumour between...

Who might be able to join this trial: - People aged 18 or older. - People who had planned surgery to remove part or all of the pancreas and duodenum (a section of the small intestine), with or without additional blood vessel or liver surgery performed through an open abdominal incision, at Strasbourg University Hospita...

**Who might be able to join this trial:** - People aged between 18 and 75 years old (inclusive), of any gender. - People who have been diagnosed with a specific type of pancreatic cancer (pancreatic ductal adenocarcinoma or IPMN carcinosis) confirmed by laboratory testing of tissue or cells, and whose cancer has not r...

**Who might be able to join this trial:** - Adults aged 18 or older, of any sex - People who have been diagnosed with an advanced gastroenteropancreatic neuroendocrine tumour (a type of tumour affecting the digestive system or pancreas), confirmed by tissue testing - People who have at least one measurable tumour that...

Who might be able to join this trial: - You are between 18 and 75 years old (any gender) and are willing to sign a consent form after understanding what the trial involves - You are well enough to carry out basic daily activities, with an activity/health status score in the acceptable range (confirm with trial site) -...

**Who might be able to join this trial:** **For patients:** - The person must provide documented informed consent (or have a legally authorized representative do so) - The person must be 18 years of age or older - The person must have a performance status of ECOG 2 or below, meaning they are able to carry out some dai...

Who might be able to join this trial: - People who are willing and able to give written consent to participate - People who are 18 years of age or older - People who have no history of cancer outside of the pancreas - People who did not have a bile duct drainage procedure before surgery - People who have confirmed panc...

**Who might be able to join this trial:** - People who are willing to participate and have signed a consent form agreeing to take part in the study - People aged 18 to 75 years old (male or female) - People who have been diagnosed with pancreatic cancer that has spread to the liver, confirmed by a tissue sample (biops...

Who might be able to join this trial: - People aged 18 to 80, of any gender, who have signed a consent form to participate - People who have been diagnosed with a specific type of pancreatic cancer called pancreatic ductal adenocarcinoma, confirmed by laboratory testing of tissue - People whose pancreatic cancer has no...

**Who might be able to join this trial:** - You must be 18 years old or older. - You must have been diagnosed with a specific type of pancreatic cancer (carcinoma, adenocarcinoma, or ductal adenocarcinoma) that is either locally advanced, resectable (able to be removed by surgery), or borderline resectable — confirmed...

**Who might be able to join this trial:** - People aged 50 or older who have been diagnosed with pancreatic cancer - People who have high blood pressure, with a reading of 140/90 mmHg or higher - People whose pancreatic cancer has been confirmed by laboratory testing of tissue samples, and whose cancer has either sprea...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic head cancer (either confirmed by tissue biopsy or agreed upon by a specialist medical team), who have yellowing of the skin caused by the tumour blocking the bile duct, and who are planned to have a major surgery to remove the a...

Who might be able to join this trial: - People who have chosen to take part voluntarily and have signed a consent form - Adults aged 18 to 75 years old, of any gender - People diagnosed with advanced pancreatic cancer (either spread to other parts of the body or unable to be removed by surgery), with at least one measu...

Who might be able to join this trial: - People aged 18 or older - People with pancreatic cancer (PDAC) that has spread or cannot be surgically removed, and whose cancer has continued to grow after chemotherapy, or who were unable to tolerate or were not eligible for chemotherapy - People with non-small cell lung cancer...

Who might be able to join this trial: - Adults aged 18 years or older - People who are already scheduled to have an endoscopic ultrasound examination (a procedure where a small camera with a sound-wave device is passed into the digestive tract to look at nearby organs) Who may not be able to join: - People under the a...

**Who might be able to join this trial:** - People who have been diagnosed with a slow-growing, non-aggressive type of pancreatic cyst called an IPMN (intraductal papillary mucinous neoplasm) that is currently being monitored - People who have been diagnosed with a more serious form of IPMN, or a type of pancreatic can...

**Who might be able to join this trial:** - People aged 18 years or older. - People who have been diagnosed with pancreatic cancer (PDAC) that has been assessed by tissue sample or imaging as removable by surgery, borderline removable, or locally advanced (spread within the area but not to distant parts of the body)....

**Who might be able to join this trial:** - You have been diagnosed with advanced pancreatic cancer (adenocarcinoma type) that has spread to other parts of the body, confirmed by a biopsy or lab test. - You have at least one tumor that can be measured on a CT scan, MRI, or PET scan. - If you are a woman who could beco...

**Who might be able to join this trial:** - You must be 18 years of age or older at the time of signing the consent form - You have been diagnosed with an advanced solid tumor (such as pancreatic cancer or non-small cell lung cancer) that has been confirmed by a tissue or cell sample, and your cancer has gotten worse o...

Who might be able to join this trial: - People aged 18 to 75 years old - People who have been confirmed through a tissue or cell sample to have pancreatic cancer that started in the ductal lining of the pancreas, and whose cancer cannot be removed by surgery and has either spread locally or to other parts of the body (...

Who might be able to join this trial: - People who identify as Chinese (male or female) - People aged 18 years or older - People with pancreatic cancer who are planned to have pancreas surgery at the hospital running this trial - People who have agreed to take part in the Pancreatobiliary Surgery Cohort Study and have...

Who might be able to join this trial: - People who fully understand the study and are willing to sign a consent form agreeing to take part - People aged 18 to 80 years old - People who have been diagnosed with pancreatic neuroendocrine tumours (any grade) through a tissue or cell sample, and whose condition has continu...

Who might be able to join this trial: - People aged 18 or older. - People who have been diagnosed with a specific type of pancreatic cancer called pancreatic ductal adenocarcinoma, confirmed by a tissue or cell sample. - People whose cancer has spread to a limited number of places in the body — between one and five sep...

**Who might be able to join this trial:** - People who are able to give voluntary, informed consent and are willing to follow all study procedures from start to finish. - People aged 18 or older (or the adult age as defined by local rules). - People with a cancer diagnosis confirmed by tissue or cell testing, where th...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form. - People aged 18 to 80 years old. - People whose general physical health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical...

**Who might be able to join this trial:** - People aged 18 or older. - People who have been diagnosed with a specific type of pancreatic cancer called pancreatic ductal adenocarcinoma, confirmed through a tissue or cell sample. - People whose cancer has spread to nearby areas or to other parts of the body. - People wh...

Who might be able to join this trial: - People who have been diagnosed with pancreatic cancer through laboratory testing and whose doctors have determined they need combination immunotherapy based on clinical guidelines - People who have signed and dated a consent form agreeing to take part in the trial - People who ar...

Who might be able to join this trial: - People who are able to understand the study and are willing to sign a written consent form. - People aged 18 to 80 years old. - People with a general health and activity level rated as fairly good (rated 0–2 on a standard scale used by doctors to measure how cancer affects daily...

Who might be able to join this trial: - Adults aged 18 years or older. - People with a confirmed solid tumour diagnosis (proven by biopsy or lab testing) that fits into one of the trial's specific cancer groups or the general "Mix of Solid Tumors" group. - People whose cancer is being treated with the aim of a cure, wi...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of enrollment - People who have been diagnosed with pancreatic or colorectal cancer confirmed through a tissue or cell sample (note: neuroendocrine tumors of the pancreas or colon are not included) - People whose cancer is at an advanced s...

Who might be able to join this trial: - People who are already scheduled for a routine chest and/or abdominal CT scan (without contrast dye) for a reason unrelated to the pancreas. Who may not be able to join: - People who have a history of pancreatic cancer. - People who have previously had surgery on the chest or ab...

**Who might be able to join this trial:** - You are able to understand and are willing to sign a consent form agreeing to take part in the study. - You are 18 years of age or older. - You are generally healthy enough to be active and care for yourself, with only minor limitations on physical activity (confirm with tri...

Who might be able to join this trial: - People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer), confirmed by a lab test, who have not yet received any systemic treatment for advanced or spread disease. Tumors with mixed cell types are allowed if the pancreatic adenoc...

Who might be able to join this trial: - You are between 18 and 80 years old (male or female) - You have a growth or abnormal area in your pancreas that was seen on a scan (such as an ultrasound, MRI, CT, or PET-CT) and doctors strongly suspect it could be pancreatic cancer that needs a biopsy to help confirm the diagno...

**Who might be able to join this trial:** - You have been diagnosed with pancreatic cancer (PDAC) confirmed by a tissue or cell sample test - A recent CT scan and MRI (done within the last month) has shown that the cancer has not spread to other parts of the body - You are already enrolled in, or able to enroll in, a s...

**Who might be able to join this trial:** - Adults aged 18 or older. - People who are scheduled for a procedure called echo-endoscopy (a scan using a camera and ultrasound inside the body) where a fine needle biopsy — taking a small tissue sample — is planned or being considered. - People where a pancreatic lesion (an...

**Who might be able to join this trial:** - Imaging results that suggest borderline resectable or locally advanced pancreatic ductal adenocarcinoma (a type of pancreatic cancer), confirmed or to be confirmed through tissue or cell samples - A doctor has determined that a laparoscopy (a procedure to look inside the abd...

**Who might be able to join this trial:** - People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer) that, based on scans (CT or MRI) and an internal ultrasound procedure, appears to be limited to the pancreas and nearby lymph nodes. - People who have had one previous round...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with a condition called IPMN (a type of pancreatic cyst), whether or not they are having surgery for it - People who are willing to sign a consent form agreeing to take part in the study - For patients whose data is being collected...

**Who might be able to join this trial:** - You have been newly diagnosed with pancreatic cancer that has either spread to nearby areas and cannot be removed by surgery (Group 1), or has spread to other parts of the body (Group 2), confirmed by a tissue or cell sample. - You are able to receive an initial course of ch...