Phase 3 study for people with Pancreatic Cancer

Recruiting Phase 3

Sources: ClinicalTrials.gov Checked: 12 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 3
Sponsor Revolution Medicines, Inc.
Registry number NCT07491445
Started 9 March 2026 Today 16 October 2026 Estimated completion 1 June 2028

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
St. George Hospital Kogarah NSW Recruiting
Prince of Wales Hospital Randwick NSW Recruiting
Calvary Mater Newcastle Waratah NSW Recruiting
Royal Brisbane and Women's Hospital Herston QLD Recruiting
Epworth HealthCare East Melbourne VIC Recruiting
Austin Health, Olivia Newton-John Cancer Research & Wellness Centre Heidelberg VIC Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 12 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 900

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* At least 18 years old and has provided informed consent.

* Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

* Histologically or cytologically confirmed pancreatic adenocarcinoma.

* Diagnosis of metastatic disease ≤ 6 weeks prior to informed consent.

* Documented RAS mutation status, either mutant or wild-type.

* Measurable disease per RECIST v1.1.

* Adequate organ function (bone marrow, liver, kidney, coagulation).

* Able to take oral medications.

Exclusion Criteria:

* Prior treatment with systemic anticancer therapy in metastatic setting or prior RAS-targeted therapy in any treatment setting.

* Active or known history of untreated central nervous system metastatic disease.

* Any conditions that may affect the ability to take or absorb study drug.

* Major surgery within 28 days prior to randomization.

* Patient is unable or unwilling to comply with protocol-required study visits or procedures.

Dates on the record

Started 9 March 2026
Estimated completion 1 June 2028
Registry last updated 2 October 2026
Checked by Voxsanity 12 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 2 October 2026.
  • This page last checked by Voxsanity: 12 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.