Prostate Cancer
Plain English clinical trial information, updated daily from ClinicalTrials.gov and public government registries. Not medical advice.
How these figures are counted
- Trials on record is every trial tagged to this condition at any stage, except those withdrawn before starting or terminated early. Most are completed rather than ongoing, so this is a measure of research history, not of current activity. It is also smaller than the sitewide "trials tracked" figure, which does include withdrawn and terminated trials.
- Recruiting now counts only trials whose registry status is "Recruiting". Trials listed as not yet recruiting or enrolling by invitation are excluded, so this understates how many may open to new participants soon.
- Australian sites counts trials counted under "Recruiting now" that list at least one Australian site. A site being listed does not mean it is currently enrolling, and Australian trials registered only on ANZCTR are not counted yet, so this understates local availability.
- Phase 3 trials counts trials counted under "Recruiting now" that are at Phase 3.
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Understanding Prostate Cancer
The prostate is a small gland, roughly the size of a walnut, that sits below the bladder in men and people assigned male at birth. It plays a role in producing fluid that forms part of semen. Prostate cancer occurs when some of the cells in this gland begin to grow in an abnormal, uncontrolled way. It is often a slow-growing cancer, and in many cases it stays contained within the prostate for a long time. However, some forms can grow and spread more quickly, which is why doctors assess each case individually to understand how the cancer is behaving.
Prostate cancer is the most commonly diagnosed cancer among Australian men, with around 24,000 new cases recorded each year. The risk increases with age, and it is most often diagnosed in men over 65. Having a father or brother who has had prostate cancer can also raise a person's risk. Many men are diagnosed through routine PSA blood tests or digital rectal examinations before they have noticed any symptoms at all, which means it is often caught at an early stage.
Treatment options vary widely depending on how advanced the cancer is, how quickly it appears to be growing, and the overall health of the person diagnosed. For slow-growing, early-stage prostate cancer, doctors may recommend a period of careful monitoring called active surveillance, where no immediate treatment is given but the cancer is watched closely over time. Other options that doctors commonly discuss include surgery to remove the prostate, radiation therapy, and hormone therapy, sometimes used on their own or in combination. A specialist medical team will talk through which approaches might be most suitable for each individual situation.
This overview is an AI generated summary written from public medical sources and checked on a sample basis. It is general information, not medical advice or a diagnosis. Always speak with your doctor about your situation. How we use AI
Can you access treatment for Prostate Cancer in Australia right now? Here's what's publicly known.
- 3 PBS-subsidised medicines are mapped to Prostate Cancer on the Pharmaceutical Benefits Scheme, listed below. Your doctor can advise whether a PBS-subsidised option is appropriate for you.
- 47 clinical trials currently recruiting at Australian sites for Prostate Cancer.
Information on this site does not constitute medical advice. Data is sourced from publicly available government registries. Always consult your doctor before making any health decisions. Trial status should be verified directly with the trial site.
PBS-subsidised medicines for Prostate Cancer
3 medicines listed on the PBS for Prostate Cancer. Filter by authority type, or open the full table below.
Full PBS medicines table 3 listed
These medicines are listed on the Pharmaceutical Benefits Scheme (PBS) for the specific indications shown. A listing does not mean a medicine is right for you; your doctor decides what is appropriate. Prices shown are the PBS-determined dispensed price. Most patients pay only the standard co-payment, up to AU$25.00 per script (general) or AU$7.70 (concession or Safety Net) in 2026, with the Australian Government subsidising the rest.
| Medicine | Brand(s) | Listed for | ||
|---|---|---|---|---|
| Apalutamide | Erlyand | Castration resistant non-metastatic carcinoma of the prostate | AU$3553.3 | |
| Darolutamide | Nubeqa | Castration resistant non-metastatic carcinoma of the prostate | AU$3375.64 | |
| Enzalutamide | Xtandi | Castration resistant non-metastatic carcinoma of the prostate | AU$3150.63 |
Source: Pharmaceutical Benefits Scheme (PBS), © Commonwealth of Australia. Data used and redistributed under permission; not modified from its original wording where displayed verbatim.
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Become a founding memberResearch pipeline
Where trials for Prostate Cancer currently sit in the development pipeline. The funnel shape shows how few drugs reach later phases in general; the counts are this condition's actual trial numbers.
Most active research sponsors
Organisations with the most recruiting trials for Prostate Cancer.
Where trials are running
Clinical trial sites for Prostate Cancer by country. Australia is highlighted.
Clinical trials for Prostate Cancer
Showing 789 of 789 trials
The plain English eligibility text on each trial below is an AI generated summary of the official criteria, checked on a sample basis. How we use AI
🇦🇺 NCT00554229 · AstraZeneca Phase 3 · 31 countries
Who might be able to join this trial: - You have been diagnosed with prostate cancer that has spread to the bones - Your PSA (a protein measured in a blood test related to prostate cancer) has been rising over the past month - You have no pain, or only mild pain, caused by your prostate cancer - You are currently havin...
🇦🇺 NCT00617669 · AstraZeneca Phase 3 · 26 countries
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that has spread to the bones. - Your PSA (a protein measured by a blood test used to monitor prostate cancer) levels have been rising, with a test result taken within the last year. - You are currently being treated to lower testos...
🇦🇺 NCT01078662 · AstraZeneca Phase 2 · 6 countries
**Who might be able to join this trial:** - You have been tested and confirmed to carry a harmful (or possibly harmful) change in the BRCA1 or BRCA2 gene (a gene mutation linked to cancer risk), confirmed before joining the study - You have a solid tumour (a type of cancer growth) that has been confirmed, and there are...
🇦🇺 NCT01977651 · Astellas Pharma Global Development, Inc. Phase 4 · 20 countries
Who might be able to join this trial: - You have been diagnosed with prostate cancer that has spread (metastatic) and confirmed by a tissue biopsy to be a specific type called adenocarcinoma. - You are currently receiving hormone therapy to lower testosterone (using injections or implants called GnRH analogues) or have...
🇦🇺 NCT02043678 · Bayer Phase 3 · 19 countries
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by a lab test on tissue) - You are male and at least 18 years old - Your prostate cancer has been shown to be getting worse, either through rising PSA blood test results or through...
🇦🇺 NCT02677896 · Astellas Pharma Global Development, Inc. Phase 3 · 24 countries
**Who might be able to join this trial:** - Adults (as defined by local law at the time of signing consent) may be considered. - People who have been diagnosed with a specific type of prostate cancer confirmed by laboratory testing of tissue or cell samples — specifically adenocarcinoma, but not certain rare subtypes...
🇦🇺 NCT03834519 · Merck Sharp & Dohme LLC Phase 3 · 20 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by lab testing of a tissue or cell sample) - People whose prostate cancer continued to grow or spread while receiving hormone-blocking treatment (or after surgical removal o...
🇦🇺 NCT03840200 · Hoffmann-La Roche Phase 1 · 5 countries
**Who might be able to join this trial:** - People who are reasonably active and able to care for themselves (rated 0 or 1 on a standard activity scale used by doctors) - People with a life expectancy of at least 3 months - People who are able to swallow tablets or capsules - People whose blood counts fall within acce...
🇦🇺 NCT03522064 · St Vincent's Hospital, Sydney Phase 2 · 1 country
**Who might be able to join this trial:** - You are male and have been diagnosed with prostate cancer (specifically a type called adenocarcinoma, confirmed by a tissue test) - Your cancer has a specific type of DNA repair fault called a "homologous recombination defect" (HRD), confirmed by a validated genetic test on...
🇦🇺 NCT04221542 · Amgen Phase 1 · 10 countries
**Who might be able to join this trial:** *(Note: This trial has multiple parts with different requirements. The trial site will determine which part, if any, a person may be considered for.)* **General requirements that apply to all parts:** - People diagnosed with prostate cancer that has spread to other parts of...
🇦🇺 NCT04606446 · Pfizer Phase 2 · 5 countries
**Who might be able to join this trial:** - People who have been diagnosed with locally advanced or metastatic breast cancer that is oestrogen receptor-positive and HER2-negative (ER+HER2-), castration-resistant prostate cancer, or non-small cell lung cancer that has not responded to or cannot tolerate standard treatm...
🇦🇺 NCT05184790 · University of Sydney Not Applicable · 1 country
Who might be able to join this trial: - You are scheduled to receive radiation therapy for cancer of the brain, breast, head and neck, kidney, liver, pancreas, prostate, or spine — or for a heart rhythm condition — at a participating treatment centre. - You will have a CT planning scan and at least one cone beam CT sca...
🇦🇺 NCT05393791 · Leiden University Medical Center Phase 2 · 2 countries
Who might be able to join this trial: - People who are willing and able to give their informed consent to participate - People aged 18 or older - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue or cell sample - People who are currently receivi...
🇦🇺 NCT05521412 · Peter MacCallum Cancer Centre, Australia Phase 2 · 1 country
**Who might be able to join this trial:** - The person has given written consent to participate in the trial. - The person is male and aged 18 or older at the time of signing consent. - The person has a confirmed diagnosis of prostate cancer (adenocarcinoma), or a clear diagnosis of prostate cancer that has spread to...
🇦🇺 NCT05560659 · Peter MacCallum Cancer Centre, Australia Phase 2 · 2 countries
**Who might be able to join this trial:** - Men aged 18 years or older at the time of screening - People who have given written consent to participate in the trial - People who have been diagnosed with prostate cancer (adenocarcinoma type), confirmed through a tissue sample (biopsy) - People who have already had treatm...
🇦🇺 NCT05720130 · AdvanCell Pty Limited Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has spread to other parts of the body (metastatic), confirmed by a tissue biopsy showing a specific type of cancer called adenocarcinoma. - People whose cancer is getting worse, shown by either a significant rise in a...
🇦🇺 NCT05800665 · Genentech, Inc. Phase 1 · 7 countries
Who might be able to join this trial: - People who are generally well enough to carry out daily activities with little to no limitation (this is measured using a standard scale called ECOG, where a score of 0 or 1 is required) - People who have been diagnosed with prostate cancer that has spread to other parts of the b...
🇦🇺 NCT05818683 · Janssen Research & Development, LLC Phase 1 · 3 countries
Who might be able to join this trial: - You have been diagnosed with metastatic prostate cancer that no longer responds to hormone therapy (called castration-resistant prostate cancer, or mCRPC), confirmed by a tissue biopsy, depending on which part of the trial you are being considered for - For some parts of the tria...
🇦🇺 NCT05997615 · Vir Biotechnology, Inc. Phase 1 · 4 countries
Who might be able to join this trial: - People who have prostate cancer that has spread to other parts of the body, confirmed by at least one scan (CT, MRI, or bone scan). - People whose cancer has continued to grow or spread, shown by rising PSA levels on at least two tests taken a week apart, new or growing tumours...
🇦🇺 NCT06095089 · Janssen Research & Development, LLC Phase 1 · 4 countries
Who might be able to join this trial: - People who have been confirmed through a tissue sample (biopsy) to have a type of prostate cancer called adenocarcinoma. Adenocarcinoma that also has small cell or neuroendocrine features is allowed, but purely small cell carcinoma or certain other rare types are not. - People wh...
🇦🇺 NCT06136624 · Merck Sharp & Dohme LLC Phase 3 · 36 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, not small cell type), confirmed by a lab test on a tissue or cell sample. - People whose prostate cancer continued to grow or spread while receiving hormone-suppressing treatment (or...
🇦🇺 NCT06136650 · Merck Sharp & Dohme LLC Phase 3 · 39 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed through a tissue or cell sample - People whose prostate cancer has continued to grow or spread while receiving hormone-suppressing treatment (androgen deprivation therapy, o...
🇦🇺 NCT06267729 · AstraZeneca Phase 2 · 3 countries
**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form. - People who have a confirmed diagnosis of prostate cancer that has spread to other parts of the body (metastatic), is a specific cell type called adenocarcinoma, and does not have certain aggressive features (...
🇦🇺 NCT06279260 · Melbourne Health Not Applicable · 1 country
Who might be able to join this trial: - People who agree to take part and give their consent - People between the ages of 18 and 90 years old - People who have been diagnosed with localised prostate cancer (cancer that has not spread beyond the prostate) - People who are receiving care at a hospital that is partnered w...
🇦🇺 NCT06353386 · Merck Sharp & Dohme LLC Phase 2 · 20 countries
**Who might be able to join this trial:** - People who have a confirmed diagnosis of prostate adenocarcinoma (a specific type of prostate cancer), not including a type called small cell. - People whose prostate cancer has gotten worse, and who have had hormone-suppressing treatment (ADT) or surgical removal of the tes...
🇦🇺 NCT06450106 · SURGE Therapeutics Phase 1 · 2 countries
Who might be able to join this trial: - People who are male and aged 18 years or older at the time of signing consent - People who have a confirmed prostate cancer diagnosis (confirmed through tissue testing) and are scheduled to have their prostate surgically removed within 28 days of the screening visit - People whos...
🇦🇺 NCT06492122 · Full-Life Technologies UK Limited Phase 1 · 4 countries
Who might be able to join this trial: - People who have been diagnosed with prostate cancer that has spread to other parts of the body and is no longer responding to hormone therapy (confirmed by a tissue or cell sample). - People aged 18 years or older. - People who are willing and able to sign a consent form and foll...
🇦🇺 NCT06496256 · Palette Life Sciences, Inc. Not Applicable · 2 countries
**Who might be able to join this trial:** - Adults aged 18 or older - People whose overall health and ability to carry out daily activities is rated at a good level (a score of 0 or 1 on a standard oncology scale) - People whose surgical notes confirm that both nerve bundles alongside the prostate were successfully pr...
🇦🇺 NCT06520345 · Telix Pharmaceuticals (Innovations) Pty Limited Phase 3 · 6 countries
**Who might be able to join this trial:** - Men aged 18 or older who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample test. - People who are reasonably active and able to care for themselves, and whose doctors estimate they have at least 6 months to li...
🇦🇺 NCT06547398 · Royal North Shore Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are over 18 years of age - People who have been diagnosed with prostate cancer confirmed by a biopsy - People whose planned treatment is radiation therapy to the prostate only (no surgery or other treatment) - People who are reasonably active and able to care for thems...
🇦🇺 NCT06594926 · Australian and New Zealand Urogenital and Prostate Cancer Trials Group Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample - People who are 18 years of age or older - People who are generally able to carry out daily activities with no or minimal limitations (as assessed...
🇦🇺 NCT06780670 · Novartis Pharmaceuticals Phase 3 · 12 countries
Who might be able to join this trial: - Adults aged 18 years or older. - People whose general health and ability to carry out daily activities falls within a certain range, as measured by a standard medical scoring system called ECOG (scores 0 to 2, meaning fully active to capable of limited self-care). - People who ha...
🇦🇺 NCT06784193 · Olema Pharmaceuticals, Inc. Phase 1 · 2 countries
Who might be able to join this trial: - People with advanced or spreading breast cancer that is ER-positive and HER2-negative, a type of advanced prostate cancer that no longer responds to hormone treatment (mCRPC), or a type of lung cancer called non-small cell lung cancer (NSCLC) — depending on which part of the tri...
🇦🇺 NCT06830850 · Atridia Pty Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are able to understand what the trial involves, including possible side effects, and who choose to take part voluntarily - People whose bone marrow and other major organs are functioning well enough (as determined by the trial site through testing) - People whose l...
🇦🇺 NCT06863272 · Merck Sharp & Dohme LLC Phase 2 · 19 countries
Who might be able to join this trial: - People who have been diagnosed with a type of prostate cancer called adenocarcinoma, confirmed by a tissue or cell sample, that is not the small cell type. - People whose prostate cancer continued to grow or spread while they were on hormone-reducing therapy (or after surgical re...
🇦🇺 NCT06879041 · AstraZeneca Phase 1 · 3 countries
Who might be able to join this trial: - People who are relatively well and able to carry out daily activities, rated 0 or 1 on a standard health performance scale used in cancer care. - People who have been diagnosed with a specific type of prostate cancer called adenocarcinoma, confirmed by laboratory testing, and wit...
🇦🇺 NCT06907641 · St Vincent's Hospital, Sydney Phase 2 · 1 country
Who might be able to join this trial: - Men aged 18 or older - People who are willing to participate and able to sign a consent form showing they understand what the study involves - People who have previously had their prostate removed (radical prostatectomy) due to a confirmed prostate cancer diagnosis - People whose...
🇦🇺 NCT06952803 · AstraZeneca Phase 3 · 28 countries
**Who might be able to join this trial:** - You are male and have been diagnosed with prostate cancer (confirmed by a tissue sample/biopsy). - You have either newly diagnosed high-risk prostate cancer (cancer that has not spread far, but is considered aggressive) or your cancer has come back after prostate removal sur...
🇦🇺 NCT06991556 · Novartis Pharmaceuticals Phase 2 · 15 countries
**Who might be able to join this trial:** - People whose general physical functioning is reasonably well-preserved, rated on a standard medical scale as 0, 1, or 2 out of 4 (meaning able to carry out at least some daily activities) - People who have been diagnosed with prostate cancer confirmed by tissue testing to be...
🇦🇺 NCT07028853 · Pfizer Phase 3 · 26 countries
**Who might be able to join this trial:** - Male participants who are 18 years of age or older at the time of screening (or the minimum age required by local rules). - People whose prostate cancer has been confirmed by a tissue or cell sample as adenocarcinoma (a specific type of prostate cancer), without certain aggr...
🇦🇺 NCT07052214 · Telix Pharmaceuticals (Innovations) Pty Limited Phase 3 · 1 country
**Who might be able to join this trial:** - Men who are at least 18 years old - Men where prostate cancer is suspected by their doctor, and a template biopsy (a type of prostate tissue sampling procedure) has been planned, based on either a recent MRI scan result or non-imaging risk factors (see below) - Men whose rec...
🇦🇺 NCT07140900 · Amgen Phase 1 · 3 countries
**Who might be able to join this trial:** - People who have been confirmed through lab testing (tissue or cell samples) to have prostate cancer of the adenocarcinoma type — mixed types (such as adenocarcinoma combined with a neuroendocrine component) are not permitted. - People who were diagnosed with prostate cancer...
🇦🇺 NCT07164443 · Janssen Research & Development, LLC Phase 3 · 17 countries
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically adenocarcinoma) confirmed by a tissue sample (biopsy). - People whose prostate cancer has spread to bones or lymph nodes (or both), is no longer responding to hormone-lowering treatment, and has no clear signs of s...
🇦🇺 NCT07223372 · Bayer Not Applicable · 1 country
Who might be able to join this trial: - People who are male and have been diagnosed with prostate cancer that has spread to other parts of the body, and whose cancer still responds to hormone treatment (known as metastatic hormone-sensitive prostate cancer) - People who have been dispensed at least one of the following...
🇦🇺 NCT07225946 · Janssen Research & Development, LLC Phase 3 · 17 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed through a tissue sample test - People whose prostate cancer has spread to other parts of the body at the time of screening, as determined by the study doctor - People who a...
🇦🇺 NCT07226986 · Novartis Pharmaceuticals Phase 2 · 7 countries
Who might be able to join this trial: - Participants must have signed a consent form before taking part in the study. - Participants must be adults aged 18 or older. - Participants must have a reasonable level of physical functioning, rated on a standard medical scale from 0 (fully active) to 2 (able to care for onesel...
🇦🇺 NCT07259213 · Radiopharm Theranostics, Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give informed consent before any study procedures begin, and who are willing to follow all study requirements. - Men aged 18 or older. - People who have a confirmed diagnosis of prostate cancer that has either spread to other parts of the b...
🇦🇺 NCT07277270 · GlaxoSmithKline Phase 1 · 3 countries
Who might be able to join this trial: - People whose general health and ability to carry out daily activities is rated at a good level (scored 0 or 1 on a standard health scale), with no worsening in the 2 weeks before starting the trial - People whose organs (such as kidneys and liver) are functioning adequately - Peo...
🇦🇺 NCT07287150 · Hoffmann-La Roche Phase 2 · 11 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (specifically adenocarcinoma) confirmed by a laboratory tissue or cell test, without certain aggressive subtypes called small-cell or neuroendocrine features - People whose prostate cancer has spread to other parts of the b...
🇦🇺 NCT07529717 · AstraZeneca Phase 2 · 3 countries
Who might be able to join this trial: - People who have been confirmed through a tissue sample (biopsy) to have prostate cancer, either the common gland-cell type (adenocarcinoma) or a less common type involving nerve-like cells (neuroendocrine differentiated prostate cancer). - People whose testosterone has been reduc...
🇦🇺 NCT07552922 · St Vincent's Hospital, Sydney Not Applicable · 1 country
Who might be able to join this trial: - Men who have high-risk prostate cancer that has come back (shown by rising PSA levels after treatment) and have not yet had hormone-blocking therapy, with or without additional hormone-targeting drugs - Men who have already had hormone-blocking therapy, with or without additional...
🇦🇺 NCT07567846 · Genentech, Inc. Phase 2 · 2 countries
**Who might be able to join this trial:** - People who are generally well enough to carry out light activity and care for themselves (a measure called ECOG Performance Status of 0 or 1) - People with a life expectancy of at least 3 months - People whose prostate cancer has been confirmed by a tissue or cell sample (bio...
🇦🇺 NCT07570979 · Novartis Pharmaceuticals Phase 1 · 3 countries
Who might be able to join this trial: - People whose overall health and ability to carry out daily activities meets a certain minimum level, as measured by a standard oncology scoring system (confirm with trial site) - People who have had their prostate cancer confirmed by a tissue or cell sample as a type called adeno...
🇦🇺 NCT07590934 · AstraZeneca Phase 2 · 7 countries
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that has been confirmed by a tissue sample as a specific type called adenocarcinoma (not rare types like small cell, neuroendocrine, or others) - Doctors expect you to live for at least 3 months or more - You are generally able to...
🇦🇺 NCT07608848 · Integrated Haematology and Oncology Network Early Phase 1 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have a confirmed diagnosis of advanced or metastatic breast cancer or prostate cancer (confirmed by a tissue or cell sample test) - You are generally well enough to carry out light activity and care for yourself (your doctor will assess...
NCT00034216 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older and have a known or suspected cancer, as well as healthy volunteers in the same age range. - People whose physical functioning falls within a certain range, rated on a standard medical scale from fully active (0) to limited self-care (3) —...
NCT00451022 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - You have previously received a vaccine or immune-based treatment (such as poxviral vaccines or other gene-based therapies) as part of a cancer research study at the National Cancer Institute or a linked research site. - You are 18 years of age or older. Who may not be able to jo...
NCT00756665 · University of Washington Not Applicable · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer through a biopsy, where the laboratory confirmed it is a specific type called adenocarcinoma. - People whose prostate cancer appears to be contained within or near the prostate and has not spread to nearby lymph nodes or ot...
NCT00923221 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with prostate cancer Who may not be able to join: - Children and anyone under the age of 18 Important: Always verify eligibility with the trial site directly before applying.
NCT00969111 · Proton Collaborative Group Not Applicable · 1 country
Who might be able to join this trial: - You have prostate cancer that was treated mainly with surgery to remove the prostate (whether done through open surgery, keyhole surgery, or robot-assisted surgery). - Your PSA level (a blood marker for prostate cancer) was no higher than 20 ng/ml. Who may not be able to join: -...
NCT01050504 · University of Washington Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with bladder, urothelial, or prostate cancer — whether the cancer is confined to the original organ or has spread — where a tissue sample can be taken from the primary site, a bone deposit, or a soft tissue deposit with low risk of complications - People wit...
NCT01194648 · University College, London Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been confirmed to have prostate cancer through a tissue sample (biopsy) taken via the rectum or through a template procedure - People whose biopsy results (from standard ultrasound-guided, MRI-targeted, or template biopsy) meet specific findings about how muc...
NCT01221168 · Centre de Recherche sur les Pathologies Prostatiques Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People who are part of a family with a known history of hereditary prostate cancer - Healthy men who do not have prostate cancer (as a comparison group) Who may not be able to join: - Peo...
NCT01441089 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - People who are currently enrolled in a clinical trial within the NIH's internal (intramural) research program and are receiving treatment as part of that trial. - People aged 3 years or older. - People who are able to understand and agree to sign a consent form, or who have a leg...
NCT01492972 · Proton Collaborative Group Phase 3 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (confirmed by a tissue sample taken within the past year) that is considered "intermediate risk" based on at least one of the following: a Gleason score of 7, a PSA level between 10 and 20, or a tumour stage of T2b–T2c. - Your can...
NCT01913106 · The Methodist Hospital Research Institute Phase 2 · 1 country
**Who might be able to join this trial:** - Your prostate cancer has come back locally (confirmed by biopsy) without spreading to other parts of the body, after you previously received hormone therapy and radiation treatment that finished at least 2 years ago - You are generally active and able to carry out daily activ...
NCT01961713 · Massachusetts General Hospital Not Applicable · 1 country
Who might be able to join this trial: - You must be male - You must be 18 years of age or older - You must have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by a tissue test) - Your prostate cancer must not have spread to other parts of the body - You must be planning to have yo...
NCT02016248 · MemorialCare Health System Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy). - You have had a biopsy within the last 12 months before signing up, unless your cancer already qualifies you for the higher-risk group in this study (confirm with trial site for details on w...
NCT02064673 · yair lotan Phase 3 · 1 country
**Who might be able to join this trial:** - People who have had a radical prostatectomy (surgical removal of the prostate) for confirmed prostate cancer - People whose cancer was confirmed by a pathologist to be at stage T1, T2, or T3 (meaning the cancer was contained or had only limited spread beyond the prostate) -...
NCT02102477 · Olof Akre Not Applicable · 4 countries
**Who might be able to join this trial:** - People aged 75 or younger at the time of joining the trial - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) confirmed by a tissue sample, who have not yet received any treatment for it - People whose overall health and mental...
NCT02381990 · Urological Research Network, LLC Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 55 and 65 years old who have been diagnosed with low or intermediate risk prostate cancer, where fewer than half of the tissue samples taken from either side of the prostate tested positive for cancer - Men older than 65 years old who have been diagnosed with pro...
NCT02391051 · University of Erlangen-Nürnberg Medical School Phase 2 · 1 country
**Who might be able to join this trial:** - People who are over 18 years old - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy) - People whose cancer has a Gleason Score (a measure of how aggressive the cancer looks under a microscope) of 6 or lower (specifically scored as...
NCT02526368 · Ivan de Kouchkovsky, MD Early Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (a type called adenocarcinoma) confirmed by a tissue sample (biopsy), which may have been done at another hospital as long as detailed results are available. - For Group A only: People who are scheduled to have their prostate su...
NCT02543905 · Institute of Cancer Research, United Kingdom Not Applicable · 1 country
**Who might be able to join this trial:** - Men of any ethnicity who have a close family history of prostate cancer — for example, a father, brother, or son diagnosed with prostate cancer before age 70; or two relatives on the same side of the family with prostate cancer where at least one was diagnosed before age 70;...
NCT02573636 · Sir Mortimer B. Davis - Jewish General Hospital Not Applicable · 1 country
Who might be able to join this trial: - People with prostate cancer that has grown beyond the outer layer of the prostate (known as T3a or more advanced stage) - People whose PSA level (a protein measured in the blood related to prostate health) is above 20 - People whose cancer has been graded as a Gleason score of 8...
NCT02594202 · National Cancer Institute (NCI) Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with prostate cancer (confirmed by biopsy) or are suspected of having prostate cancer, and who need and are willing to undergo a diagnostic procedure, treatment, or follow-up monitoring as part of their care - People who are re...
NCT02706561 · Memorial Sloan Kettering Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - People diagnosed with early-stage prostate cancer, based on their medical records, with specific cancer severity and grade scores within certain ranges (confirm with trial site for exact values) - People who have had their prostate surgically removed (called a radical prosta...
NCT02724670 · University Hospital Tuebingen Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People whose cancer is considered suitable for treatment aimed at curing the disease - People who are reasonably active and able to carry out daily activities (rated on a standard health s...
NCT02869594 · Institut Paoli-Calmettes Not Applicable · 1 country
"Who might be able to join this trial: - People who have been diagnosed with prostate cancer Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with the trial site directly before applying."
NCT02871726 · Johns Hopkins University Not Applicable · 1 country
Who might be able to join this trial: - People who are scheduled to have their first-ever prostate biopsy (a procedure to check for cancer) - People who have a higher-than-normal PSA blood test result (above 4 ng/ml) and/or an abnormal result from a physical examination of the prostate Who may not be able to join: - P...
NCT02971085 · Seoul National University Hospital Not Applicable · 1 country
Who might be able to join this trial: - Men under 80 years of age - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed through a biopsy that took at least 10 tissue samples - People whose PSA blood test result before biopsy was 10 ng/ml or lower - People whose PSA density...
NCT02997709 · University of Miami Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue test (biopsy or lab analysis). - People at any stage of prostate cancer, including those whose cancer has spread to lymph nodes or other parts of the body — in fact, patients with spread (metastatic) diseas...
NCT03034187 · University Medical Center Groningen Not Applicable · 1 country
Who might be able to join this trial: - People who have been treated for prostate cancer with the goal of curing it, and whose cancer had spread to nearby lymph nodes - People who will be receiving radiation therapy as part of their treatment, including after surgery or as an additional (adjuvant) treatment - People wh...
NCT03079323 · Universitaire Ziekenhuizen KU Leuven Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to sign a consent form and follow the treatment and follow-up schedule - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy or surgery) - People who have not received any previous treatment for prostate cancer - Peo...
NCT03237026 · National Taiwan University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed through a tissue sample examination. - People aged between 30 and 100 years old. - People who agree to undergo at least one of the following treatments for their prostate ca...
NCT03237702 · National Taiwan University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who are planning to have a prostate biopsy, or who have already had one within the past 6 weeks - Men between the ages of 30 and 100 - People who have previously been diagnosed with prostate cancer and are having a repeat biopsy, where testosterone levels are within t...
NCT03258320 · Shanghai Jiao Tong University School of Medicine Phase 3 · 1 country
Who might be able to join this trial: - People aged between 40 and 75 years old who have been diagnosed with prostate cancer confirmed by a tissue biopsy. - People whose major organs (such as the heart, liver, and kidneys) are functioning without severe problems. - People who are generally able to carry out daily activ...
NCT03294889 · University Hospital, Geneva Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to participate before any trial procedures begin - People who have been confirmed through a tissue sample (biopsy) to have prostate adenocarcinoma (a specific type of prostate cancer), without small cell features - People whose cancer st...
NCT03322891 · Emory University Not Applicable · 1 country
Who might be able to join this trial: - People who have had a prostate biopsy reviewed by pathology (laboratory specialists) at one of these locations: Emory University, Grady Memorial Hospital, Saint Joseph's Hospital, or Atlanta VA Medical Center, and whose prostate cancer has been classified as an early stage (stage...
NCT03327675 · Universitaire Ziekenhuizen KU Leuven Not Applicable · 1 country
**Who might be able to join this trial:** **Group 1 (patients planning surgery):** - You are under 75 years old and have been diagnosed with prostate cancer confirmed by a tissue biopsy (specifically a type called invasive adenocarcinoma) - Your cancer is considered intermediate to high risk, with at least a 5% chance...
NCT03354416 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - People who are at higher-than-average risk of prostate cancer due to a strong family history of the disease and/or an inherited genetic mutation affecting DNA repair. - People who have already been diagnosed with prostate cancer, or who have lesions (abnormal areas) that are cons...
NCT03408964 · Oncology Institute of Southern Switzerland Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People with a confirmed tissue diagnosis of prostate adenocarcinoma (a specific type of prostate cancer) at various stages, for whom treatment has been recommended - People who are willing and able to provide written consent to participate - *(For o...
NCT03424850 · Washington University School of Medicine Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with early-stage prostate cancer, confirmed through a tissue or cell sample test. - Your cancer is classified as either "low-risk" or "favorable intermediate-risk" based on specific test results, including your PSA level, Gleason score, and biopsy resu...
NCT03495427 · H. Lee Moffitt Cancer Center and Research Institute Phase 3 · 1 country
**Who might be able to join this trial:** - You must have previously taken part in a specific earlier study called "VANDAAM" (study MCC#18523) - Your genetic test result from that earlier study (called a Decipher score) must have come back as high-risk, meaning a score above 0.45 - You must have had your genetic test s...
NCT03650595 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 40 and 80 years of age - People who have been diagnosed with low- to intermediate-risk prostate cancer, confirmed by tissue testing, with a Gleason score of 7 or less and a primary grade of 4 or less - People whose prostate cancer is at a clinical stage of T1c or...
NCT03678025 · SWOG Cancer Research Network Phase 3 · 5 countries
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a laboratory test on a tissue or cell sample - People who still have their prostate intact, with no prior treatments aimed at the prostate cancer itself (though previou...
NCT03701581 · John Elfar Phase 3 · 1 country
**Who might be able to join this trial:** - Male patients who have prostate cancer that has not spread beyond the prostate (stages cT1c–T2c) and are planning to have a nerve-sparing robotic prostate removal surgery - People whose prostate-specific antigen (PSA) blood test result was below 15 ng/ml in the last 12 month...
NCT03753243 · Mark Garzotto, MD Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form for the trial - People who are able to understand and follow the trial's rules and procedures - People who are 18 years of age or older at the time of signing the consent form - People whose cancer can be measure...
NCT03784924 · University of Michigan Not Applicable · 1 country
Who might be able to join this trial: - Men who are suspected of having prostate cancer but have not yet been diagnosed - Men who are already scheduled for, or are due to be scheduled for, a prostate biopsy as part of their normal medical care Who may not be able to join: - Men from whom blood and urine samples cannot...
NCT03789253 · National Taiwan University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a tissue or cell sample. - You are currently on, or have previously been on, an "active surveillance" plan (a watchful waiting approach instead of immediate treatment) managed a...
NCT03802851 · University of Kansas Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have bothersome urinary symptoms, measured by a standard symptom score of 15 or higher, and/or have a large amount of urine remaining in the bladder after urinating (350mL or more), and/or rely on a catheter to empty their blad...
NCT03805919 · National Cancer Institute (NCI) Not Applicable · 1 country
Who might be able to join this trial: - Men between the ages of 30 and 75 years old - People who have a confirmed harmful or likely harmful genetic variant in a prostate cancer risk-related gene, identified by a certified laboratory — this includes variants in genes such as BRCA1, BRCA2, Lynch syndrome-related genes (M...
NCT03819101 · Gustave Roussy, Cancer Campus, Grand Paris Phase 3 · 6 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (confirmed by a tissue sample) where curative local treatment is no longer considered possible. - People aged 18 or older with a life expectancy of at least 6 months. - People whose prostate cancer has continued to grow or...
NCT03821246 · David Oh Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a laboratory tissue test — not the small cell or neuroendocrine types. - People whose surgeon has determined they are a suitable candidate for prostate removal surgery (...
NCT03824652 · Stephen Freedland Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a laboratory test. - People who had a biopsy with at least 10 tissue samples taken, with each sample examined separately to identify exactly where the cancer is located....
NCT03830788 · Center Eugene Marquis Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a biopsy - People whose prostate cancer is classified as "low risk" based on a standard medical scoring system called d'Amico — meaning the cancer is at an early sta...
NCT03833921 · Martha Mims Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a type called adenocarcinoma) confirmed by a tissue or cell sample, with cancer that has spread to other parts of the body (such as bones or soft tissue). - People who have had scans to assess all areas of disease (includi...
NCT03861676 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Early Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) - People whose general health and ability to carry out daily activities meets a certain standard (confirm with trial site) - People whose cancer is at an early clinical stage, with no...
NCT03880422 · Roswell Park Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a biopsy, at any stage or grade - People who have been prescribed or are already receiving continuous hormone therapy (to reduce testosterone) for less than 5 years - Pe...
NCT03903835 · Karolinska Institutet Phase 3 · 4 countries
**Who might be able to join this trial:** - You are a man who has been diagnosed with prostate cancer (confirmed by a tissue sample) that has spread to other parts of the body, and you are starting your first main treatment for this advanced stage - Your cancer has been found to have spread (to bones or other areas) t...
NCT03908684 · Sunnybrook Health Sciences Centre Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate, rectal, or head and neck cancer (confirmed by a tissue or cell sample), have not yet received any first-line treatment, and are planned to receive radiation therapy. - Your cancer can be measured by ultrasound or MRI scan done within 28...
NCT03914391 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 years or older - People with a PSA (prostate-specific antigen) blood test result above 4 ng/ml, which is considered higher than normal - People who are already scheduled to have a prostate biopsy (a procedure to take a small tissue sample from the prostate) Who may n...
NCT03920033 · Asan Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with intermediate- or high-risk prostate cancer, confirmed by a laboratory test on tissue samples. - People whose PSA levels have risen on more than one test to above 0.2 ng/mL but no higher than 1.0 ng/mL after having their prostate surgically remo...
NCT03972657 · Regeneron Pharmaceuticals Phase 2 · 1 country
**Who might be able to join this trial:** *For men with advanced prostate cancer (mCRPC):* - Men who have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed by lab testing, but not the pure small cell type. - Men whose PSA level is at least 4 ng/mL at the screening visit and has been ris...
NCT04004312 · Fabio Cury Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample - People with an early-stage prostate cancer (T1–T2b based on a specific staging system) with a cancer aggressiveness score (Gleason score) of 6 or...
NCT04038502 · VA Office of Research and Development Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed the required consent and privacy authorization forms - Men over 18 years of age - People with a diagnosis of prostate cancer (certain rare types — pure small-cell or pure high-grade neuroendocrine — are not eligible, but prostate cancer that shows some...
NCT04083937 · University Hospital Heidelberg Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy), with a Gleason Score and PSA level recorded - People who have had their prostate surgically removed and whose doctor has recommended radiation treatment to the area where the prostate was,...
NCT04100174 · Centre hospitalier de l'Université de Montréal (CHUM) Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer through a tissue biopsy, and whose treatment plan includes a type of internal radiation therapy (called HDR brachytherapy) combined with external beam radiotherapy aimed at curing the cancer. - People who are either fully active...
NCT04104607 · University Hospital Tuebingen Phase 1 · 1 country
**Who might be able to join this trial:** - People diagnosed with castration-resistant prostate cancer (a form of prostate cancer that has continued to grow despite hormone-reducing treatment) who have already been through three lines of treatment - People who have given written consent to participate and are able to...
NCT04104776 · Novartis Pharmaceuticals Phase 2 · 7 countries
Who might be able to join this trial: - Adults aged 18 or older who are expected to live for at least 12 weeks - People who are generally well enough to carry out daily activities with little or no limitation (as measured by a standard medical scale called ECOG 0–1) - People who have mostly recovered from side effects...
NCT04146077 · I.M. Sechenov First Moscow State Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a biopsy that collected at least 12 tissue samples - People who understand the purpose of the research, agree to take part, and are willing to sign a consent fo...
NCT04172753 · University Hospital Tuebingen Not Applicable · 1 country
Who might be able to join this trial: - You have already been told by your doctor that you need radiation therapy as part of your treatment - You are 18 years old or older (there is no maximum age limit) - You are able to understand and make your own decisions about taking part - You are willing and able to give your c...
NCT04175431 · University of Washington Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue or cell sample - People who have previously had their prostate surgically removed (radical prostatectomy) - People who have previously had radiation t...
NCT04186585 · Meddoc Phase 1 · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer and are between 18 and 80 years old - You are currently receiving hormonal treatment for your prostate cancer Who may not be able to join: - Your doctors estimate that you are not expected to live for more than 3 months - Your liver i...
NCT04212715 · King Saud University Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that has been confirmed by a tissue sample (biopsy), specifically the type called adenocarcinoma - Your prostate cancer is considered "high-risk," meaning at least one of the following applies: the cancer has grown beyond the prost...
NCT04231006 · Aarhus University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who previously had radiation treatment (either external beam radiotherapy or brachytherapy) for prostate cancer at certain stages, and whose cancer had not spread to distant parts of the body at the time of that treatment - At least 2 years have passed s...
NCT04249154 · McGill University Health Centre/Research Institute of the McGill Unive... Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (confirmed by tissue testing) and have already had their prostate removed as their main treatment, and whose cancer has one or more high-risk features — such as cancer cells found at the edges of the removed tissue, cancer...
NCT04271527 · Shanghai East Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are over 18 years old - People who have a PSA (prostate-specific antigen) blood test result between 4 and 20 ng/ml, and/or an abnormal digital rectal exam (a physical check of the prostate) - People who are willing to sign a consent form agreeing to take part in the tr...
NCT04271579 · Martini-Klinik am UKE GmbH Not Applicable · 1 country
Who might be able to join this trial: - People who are in good general health and are expected to live more than 10 years - People whose prostate cancer has come back after having their prostate surgically removed (including those who previously had a second surgery to remove the prostate, or who have had radiation the...
NCT04287088 · Turku University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who speak Finnish - People whose doctor suspects prostate cancer, based on a blood test result (PSA level) between 2.5 and 20 ng/ml, an abnormal prostate examination by their referring doctor, or both - People who are able to under...
NCT04337580 · Wake Forest University Health Sciences Phase 2 · 1 country
**Who might be able to join this trial:** - People who have prostate cancer that has continued to grow despite hormone therapy (called castrate refractory prostate cancer) and who have previously been treated with a chemotherapy drug called docetaxel for this stage of the disease - People whose cancer has been confirm...
NCT04340024 · National Cancer Centre, Singapore Not Applicable · 1 country
Who might be able to join this trial: - People who have experienced severe side effects from radiotherapy (radiation treatment) - People who have a type of cancer that is known to be particularly sensitive to radiotherapy Who may not be able to join: - People who are under 21 years old, or who are 99 years old or olde...
NCT04363164 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - People who are at least 18 years old - People whose prostate cancer has been confirmed by a tissue sample (biopsy) showing a specific type called adenocarcinoma - People who are reasonably physically active and able to care for themselves — scoring 2 or below on a standard a...
NCT04373564 · Guerbet Phase 4 · 8 countries
**Who might be able to join this trial:** - People who are neurologically normal — meaning free from unstable neurological or psychiatric conditions, as confirmed by a neurological examination at the start of the trial - People who agree to have unenhanced brain MRI scans (MRI scans without contrast dye) at the start...
NCT04402151 · Weill Medical College of Cornell University Phase 2 · 1 country
Who might be able to join this trial: - The person must be male and aged 21 years or older. - The person must be able to understand and sign a consent form, and be willing to follow the study's requirements. - The person must have a confirmed diagnosis of prostate cancer that falls into one of these categories: high-ri...
NCT04420702 · Washington University School of Medicine Not Applicable · 1 country
**Who might be able to join this trial:** - People who are over 18 years of age and are willing and able to give informed consent to participate. - People who have not previously been diagnosed with prostate cancer, and who are already scheduled to have a prostate biopsy as part of their normal medical care — this inc...
NCT04423211 · ECOG-ACRIN Cancer Research Group Phase 3 · 1 country
**Who might be able to join this trial:** - People who are male and at least 18 years old - People who have had their prostate removed (radical prostatectomy) as the main treatment for confirmed prostate cancer - People whose PSA levels have risen again after surgery (called biochemical recurrence), meeting specific P...
NCT04472338 · University of Washington Not Applicable · 1 country
**Who might be able to join this trial:** - People with a prostate who are 40 years of age or older - People who have a documented inherited gene change (found through genetic testing) in a gene known or suspected to be linked to a higher risk of prostate cancer **Who may not be able to join:** - People who have alrea...
NCT04489719 · University of Washington Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with prostate cancer confirmed by laboratory tissue analysis - People whose prostate cancer has continued to grow or spread despite having very low testosterone levels (sometimes called castration-resist...
NCT04549688 · The Hospital of Vestfold Not Applicable · 1 country
**Who might be able to join this trial:** - You are between 55 and 80 years old - Your doctors expect you to live for more than 10 years - Your prostate cancer aggressiveness score (called a Gleason score) is below 8 if you are under 75, or below 9 if you are between 75 and 80 - Your cancer appears to be contained wit...
NCT04552509 · Linda Chan, MD Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue sample (biopsy), with the biopsy taken within 12 months of joining the trial in most cases (confirm with trial site for exceptions) - People whose cancer is...
NCT04556916 · University Hospital, Montpellier Not Applicable · 1 country
**Who might be able to join this trial:** **As a Patient Participant:** - You are a man aged 41 or older who is suspected of possibly having prostate cancer - Your PSA blood test result is 4 or higher and your doctor has recommended a prostate biopsy - You are able to attend all required appointments and follow the tr...
NCT04573231 · University of Wisconsin, Madison Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with metastatic breast cancer that is HER2-negative (a specific tumour type based on lab testing) and whose tumour tests positive for a protein called the androgen receptor (AR) in at least 10% of cells **Who may not be able to join:** - People...
NCT04595019 · Institute of Cancer Research, United Kingdom Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has been confirmed by a tissue sample, and who need radical radiotherapy (high-dose radiation treatment aimed at curing the cancer) - People whose can...
NCT04610372 · British Columbia Cancer Agency Not Applicable · 1 country
**Who might be able to join this trial:** - You have signed a consent form agreeing to take part in the study - You are well enough to carry out daily activities with little or no limitation (your doctor rates your general health as reasonably good) - Your prostate cancer has been confirmed by a tissue sample (biopsy)...
NCT04612907 · Umeå University Not Applicable · 1 country
Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the study - People whose prostate cancer has been confirmed through a tissue sample (biopsy or similar test) - People with prostate cancer that has spread to a limited number of sites in the body — specifically, no mo...
NCT04625556 · Yonsei University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a urological cancer, specifically prostate cancer, kidney cancer, bladder cancer, or ureter cancer - People who have had surgery for one of these urological cancers at Severance Hospital, Sinchon, between October 2020 and October 2030 - People...
NCT04633252 · National Cancer Institute (NCI) Phase 2 · 1 country
**Who might be able to join this trial:** - A diagnosis of prostate cancer must be confirmed by a pathologist's report or tissue sample, or by a clinical history consistent with prostate cancer if no tissue sample is available. - The cancer must have spread (metastasised) to at least one site, shown on a bone scan or...
NCT04638088 · Elsan Not Applicable · 1 country
"Who might be able to join this trial: - People who are admitted to hospital for a planned surgical procedure to remove the prostate (called a radical prostatectomy) Who may not be able to join: - People who have declined or refused to give their consent to participate - People who are protected under specific French...
NCT04646434 · Roswell Park Cancer Institute Not Applicable · 1 country
Who might be able to join this trial: - Adults who have had or are currently having their prostate removed using a robot-assisted surgical procedure - People who had normal bladder control (no leaking or incontinence) before their surgery - People (or their legal representative) who understand the research nature of th...
NCT04654338 · Sunnybrook Health Sciences Centre Phase 3 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed through a tissue sample analysis - People whose cancer is considered low risk, meaning the cancer is contained within or close to the prostate, has a low grade group score (grad...
NCT04692675 · National Cancer Institute (NCI) Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a pathology lab within the last 2 years before joining the study — tissue samples must be reviewed by the NCI's Laboratory of Pathology, and a new biopsy may be coll...
NCT04694924 · Universitaire Ziekenhuizen KU Leuven Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer that is confirmed by pathology tests, where the cancer is localised or locally advanced (has not spread far from the prostate). - People who can speak, read, and understand Dutch, French, or English. - People (or their legally a...
NCT04698564 · University of Maryland, Baltimore Phase 2 · 1 country
Who might be able to join this trial: - People who are older than 40 and younger than 80 years of age - People who have a clinical suspicion or known history of prostate cancer, shown by at least one of the following: a PSA blood test result above 4ng/ml, an abnormal rectal examination finding, or a previous tissue sam...
NCT04700332 · Hoag Memorial Hospital Presbyterian Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma, confirmed by a tissue test) - People who fall into one of two groups: - **Group 1:** People with high-risk prostate cancer (based on a PSA score above 10,...
NCT04704505 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that is confirmed by a lab report to be the type called adenocarcinoma (or a mixed type where more than half is adenocarcinoma). - People who have cancer that has spread to the bones, shown by at least one spot on a bone sc...
NCT04706663 · National Cancer Institute (NCI) Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has been confirmed through laboratory testing of tissue samples. - People who have specific gene changes (variants) in certain genes, detected through any type of genetic testing. The genes involved include PIK3, AKT,...
NCT04725903 · Emory University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with high-risk prostate cancer confirmed by a tissue sample (biopsy), meeting at least one of the following: an aggressive cancer grade (Gleason score of 8 or higher); cancer that has spread to the seminal vesicles or nearby structures; a PSA level ab...
NCT04734730 · City of Hope Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a laboratory test on a tissue or cell sample - People whose prostate cancer has spread to other parts of the body, such as soft tissue or bones - People who have ha...
NCT04765150 · Jonsson Comprehensive Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 years or older - People who either have a clinical suspicion of prostate cancer or have had prostate cancer confirmed through a biopsy - People who have had or are currently having a specific type of prostate MRI scan (multi-parametric 3T MRI) at U...
NCT04794777 · Stefan Carlsson Phase 3 · 1 country
Who might be able to join this trial: - You have had surgery to remove your prostate (radical prostatectomy) to treat prostate cancer, and your PSA levels have risen above 0.2 but below 2.0 ng/mL on two separate measurements, suggesting the cancer may be returning. - A team of medical specialists has reviewed your case...
NCT04797039 · Mayo Clinic Not Applicable · 1 country
"Who might be able to join this trial: - People who have been diagnosed with Gleason 7 prostate cancer confirmed by a biopsy, and have been referred to a specialist for treatment - People for whom surgery or radiation therapy is not considered a suitable treatment option at the time of joining the trial - People whose...
NCT04808427 · National Cancer Institute (NCI) Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer through a specific type of biopsy (using ultrasound guidance with at least 12 tissue samples, plus targeted samples of any areas visible on MRI), with the diagnosis confirmed by the NCI's Pathology Laboratory - People whose...
NCT04831983 · University of Milano Bicocca Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (specifically the type called adenocarcinoma), confirmed through a tissue sample test - People whose cancer is classified as intermediate or high risk, based on a standard medical guideline called the NCCN definition - Peop...
NCT04833426 · Canisius-Wilhelmina Hospital Phase 3 · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People whose primary treatment was surgical removal of the prostate (radical prostatectomy) - People whose surgery included a procedure to spare at least...
NCT04838899 · Sunnybrook Health Sciences Centre Not Applicable · 1 country
**Who might be able to join this trial:** - People who are generally well and able to carry out daily activities with little to no limitation (based on a standard health scoring system called ECOG, at level 0 or 1) - People who have been diagnosed with prostate cancer confirmed by tissue testing, specifically a type c...
NCT04857502 · Jonsson Comprehensive Cancer Center Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer, either as a new diagnosis or as a cancer that has come back - People who have had a specific type of imaging scan called a 68Ga-PSMA-11 PET/CT scan to check the stage or restage of their prostate cancer - People whose 68Ga-...
NCT04858880 · Lund University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People with a life expectancy of more than 10 years - People who are generally well and able to carry out normal daily activities with little or no limitation (known as WHO performance status 0–1) - People whose prostate cancer was confirmed by...
NCT04868604 · Clarity Pharmaceuticals Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given their written agreement to take part in the study - People aged 18 or older - People whose overall health and ability to carry out daily activities falls within an accepted range, as measured by a standard oncology scale (called ECOG performance status...
NCT04886986 · Weill Medical College of Cornell University Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (adenocarcinoma type) confirmed by a tissue or cell sample - People whose prostate cancer has spread to other parts of the body (metastatic) and is continuing to grow despite hormone-lowering treatment, shown by rising PSA...
NCT04890613 · Senhwa Biosciences, Inc. Phase 1 · 2 countries
**Who might be able to join this trial:** **Main study group:** - People who have been diagnosed with cancer of the pancreas, prostate, breast, or ovary, confirmed by laboratory testing of a tissue or cell sample. - People whose cancer has a specific genetic change (mutation) in BRCA1, BRCA2, PALB2, or one of a long l...
NCT04894188 · National Taiwan University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men between the ages of 20 and 75 - People who have signed a consent form showing they understand what the study involves and are willing to follow its rules and requirements - People who have been diagnosed with a specific type of prostate cancer called adenocarcinoma, conf...
NCT04895839 · Gabriela Ilie Not Applicable · 5 countries
**Who might be able to join this trial:** - People who are over 18 years of age - People who have been diagnosed with prostate cancer - People who are considered safe to exercise and do strength training (those who have had a minor stroke or heart condition in the past will need written approval from their family docto...
NCT04916613 · UNICANCER Phase 3 · 12 countries
**Who might be able to join this trial:** - People who have signed a written consent form before any trial procedures begin. - Men who have been confirmed through laboratory testing (biopsy or cell sample) to have prostate cancer of the adenocarcinoma type. - Men who are 18 years of age or older at the time of signing...
NCT04947254 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent before any study procedures begin (consent can be done remotely) - People who agree to have tissue samples collected at specific points during the study - Males aged 18 years or older - People with prostate cancer that has been confirmed...
NCT04954599 · Maastricht University Medical Center Phase 2 · 3 countries
**Who might be able to join this trial:** - Adults aged 18 or older who are willing and able to sign a consent form - People with a life expectancy of at least 3 months - People who are willing to have a biopsy (a small tissue sample taken for testing) - People who are well enough to carry out basic daily activities w...
NCT04986423 · Zenith Epigenetics Phase 2 · 2 countries
**Who might be able to join this trial:** - People who are male and aged 18 or older - People who have prostate cancer that has spread to other parts of the body (metastatic), is no longer responding to hormone-lowering treatment (castration-resistant), and has been confirmed by a tissue sample (biopsy) - People who h...
NCT04992728 · University of California, San Diego Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed through a tissue test) - People who have already had, or are scheduled to have, a prostate MRI and/or surgery to remove the prostate as part of their standard c...
NCT04995198 · Prostate Cancer Clinical Trials Consortium Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer at any stage, confirmed through a tissue biopsy, a PSA blood test result greater than 100 ng/dL, or clear imaging scans showing the disease. - People who currently live in the United States, including Puerto Rico, Guam, American...
NCT05000827 · Canisius-Wilhelmina Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a biopsy showing a specific type called adenocarcinoma - People for whom doctors have determined that an extended removal of lymph nodes in the pelvis, combined with robotic surgery to remove the prostate, is the re...
NCT05001477 · Profound Medical Inc. Not Applicable · 1 country
**Who might be able to join this trial:** - You are male - You are older than 18 years of age - You have already been considered a suitable candidate for a specific prostate treatment called TULSA-PRO (confirm with trial site) - You are willing and able to read and sign a consent form agreeing to take part in the study...
NCT05011383 · VA Office of Research and Development Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to sign a consent form agreeing to follow the study schedule, attend all visits, and allow their health information to be used for research - Men aged over 18 years - People who have been diagnosed with prostate cancer (adenocarcinoma type) confirmed b...
NCT05019846 · Marco Lorenzo Bonu Phase 3 · 1 country
**Who might be able to join this trial:** - A tissue sample (biopsy) has confirmed a specific type of prostate cancer called acinar adenocarcinoma, and at least 10 biopsy samples were taken - An MRI scan of the prostate has been done to assess the local spread of the cancer - The cancer falls into the "intermediate un...
NCT05022914 · Azienda Ospedaliero-Universitaria Careggi Not Applicable · 1 country
Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the study - People who are over 18 years of age - People who have previously had their prostate surgically removed and whose laboratory results confirmed prostate adenocarcinoma (a common type of prostate cancer), who...
NCT05033301 · University Health Network, Toronto Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have finished treatment aimed at curing their prostate cancer - People who are receiving prostate cancer survivorship care at one of these specific hospitals: University Health Network (UHN), Trillium Health Partners (THP), Nia...
NCT05036226 · Medical University of South Carolina Phase 2 · 1 country
**Who might be able to join this trial:** - People who have advanced solid tumour cancer of any type (Phase I of the trial) or advanced prostate cancer with a PSA level of at least 0.1 ng/mL (Phase II of the trial) - People whose cancer diagnosis has been confirmed by a pathology report or documented clinical note - P...
NCT05038332 · University of Michigan Rogel Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who have been diagnosed with prostate cancer (confirmed through a tissue sample) and have already had their prostate surgically removed, with a PSA blood test result of 0.1 ng/mL or higher - At least 6 months must have passed between the prostate removal...
NCT05043012 · M.D. Anderson Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 or older - People who have been diagnosed with intermediate or high-risk prostate cancer (confirmed by biopsy), specifically a Gleason grade group of 2 or higher - People whose doctor is considering surgery to remove the prostate (radical prostatec...
NCT05054296 · M.D. Anderson Cancer Center Phase 2 · 1 country
Who might be able to join this trial: - People who are willing and able to give written consent to participate - People who have been confirmed through a tissue or cell sample to have prostate adenocarcinoma (a specific type of prostate cancer) - People who have cancer that has spread to other parts of the body, shown...
NCT05054413 · M.D. Anderson Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who are 21 years of age or older - People who hold board certification in Radiation Oncology, Radiation Physics, Urology, and/or Medical Oncology - People who currently work in a practice that includes treating prostate cancer patients - People who speak English Who may n...
NCT05097274 · Institute of Cancer Research, United Kingdom Not Applicable · 1 country
Who might be able to join this trial: - People who have a confirmed harmful genetic mutation in one of the following genes: BRCA1, BRCA2, MSH2, MSH6, MLH1, PMS2, CHEK2, PALB2, or ATM - People who are over 18 years of age - People who have been diagnosed with prostate cancer and are at a point where imaging to check the...
NCT05109910 · The Netherlands Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 years or older - People who have prostate cancer with a calculated risk (using a tool called the Briganti nomogram) of cancer spreading to the lymph nodes of between 5% and 20%, and whose pre-surgery scan (called a PSMA PET/CT) shows no signs o...
NCT05113537 · Vadim S Koshkin Phase 2 · 1 country
Who might be able to join this trial: - People who have been confirmed (through a tissue or cell sample) to have prostate cancer, either from a new biopsy or stored tissue. - People aged 18 years or older. - People whose prostate cancer has spread to other parts of the body (metastatic), is no longer responding to horm...
NCT05116579 · Sun Yat-sen University Not Applicable · 1 country
**Who might be able to join this trial:** - A person must be willing and able to give their informed consent to participate. - Male adults between 18 and 75 years of age may be eligible. - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has been confirmed by laboratory...
NCT05125016 · Regeneron Pharmaceuticals Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a lab test, and you do not have a type called "pure small cell carcinoma" - Your prostate cancer has spread to other parts of the body, is no longer responding to hormone-loweri...
NCT05129605 · Massachusetts General Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men between the ages of 35 and 74 - People who have not been diagnosed with prostate cancer - People whose general health suggests they are expected to live more than 10 years - People who meet the criteria for one of three groups: - **Group A:** People who have had geneti...
NCT05155501 · Weill Medical College of Cornell University Not Applicable · 1 country
Who might be able to join this trial: - People who are male - People who are aged between 40 and 80 years old - People who are scheduled to have surgery to fully remove the prostate due to prostate cancer that has not spread beyond the prostate - People who can read and speak English or Spanish - People who are willing...
NCT05163197 · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Not Applicable · 1 country
"Who might be able to join this trial: - People who are male and have a confirmed diagnosis of localized prostate cancer (confirmed through a tissue sample/biopsy) - People who are receiving a specific prostate cancer treatment called TPLA (Transperineal Laser Ablation) Who may not be able to join: - People under 18 y...
NCT05168618 · University of Utah Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - People who have been confirmed through tissue or cell testing to have prostate adenocarcinoma (a specific type of prostate cancer), but not the small cell type - People whose cancer has spread (metastatic) and continued to grow despite ongoing hormone-...
NCT05169112 · Ottawa Hospital Research Institute Phase 3 · 1 country
**Who might be able to join this trial:** - People who had prostate surgery and had a PSA level that was undetectable (below 0.02 ng/ml) within 16 weeks after the operation. - People whose risk of PSA returning within 5 years of surgery is calculated at 25% or higher, based on a specific medical scoring tool called the...
NCT05183074 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People whose prostate cancer has been confirmed through a tissue sample (biopsy or similar test) - People with localised prostate cancer (cancer that has not spread beyond the prostate) that falls into certain risk categories — low-risk,...
NCT05191680 · Cambridge University Hospitals NHS Foundation Trust Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to take part in the trial. - People aged 18 or older. - People with a general health and activity level rated as reasonably functional (scored 0–2 on a standard oncology scale called ECOG — confirm with trial site if unsure what this mea...
NCT05209243 · Instituto de Investigación en Oncología Radioterápica - Fundación Espa... Not Applicable · 1 country
**Who might be able to join this trial:** - People who have a confirmed diagnosis of prostate cancer based on a tissue sample (biopsy). - People whose prostate cancer is still responding to hormone therapy that lowers testosterone (known as castration-sensitive prostate cancer). - People with a limited number of areas...
NCT05225428 · Dana-Farber Cancer Institute Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - You have been diagnosed with, or previously had, breast cancer, ovarian cancer, pancreatic cancer, prostate cancer, colorectal cancer, kidney cancer, melanoma, or sarcoma - You are able to understand spoken or written English or Spanish in a...
NCT05241236 · Urological Research Network, LLC Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 50 to 65 who have been clinically diagnosed with low or intermediate risk prostate cancer, where fewer than half of the tissue samples taken from each side of the prostate tested positive for cancer - Men aged over 65 who have been clinically diagnosed with prostate...
NCT05242744 · Abramson Cancer Center at Penn Medicine Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with prostate cancer confirmed through laboratory testing of tissue samples - People who have prostate cancer that has spread to other parts of the body, with at least one affected area visible on standa...
NCT05295407 · Endeavor Health Not Applicable · 1 country
Who might be able to join this trial: - People who are scheduled to have a prostate biopsy to check for prostate cancer - People between the ages of 40 and 69 years old - People who identify as one of four specific ethnic backgrounds: Caucasian, African American, East Asian, or Latino - People whose PSA level (a protei...
NCT05306600 · Hospital Moinhos de Vento Not Applicable · 1 country
**Who might be able to join this trial:** **For people with breast cancer (Arm 1):** - You are a woman aged 18 or older - You are a Brazilian national - Your breast cancer diagnosis has been confirmed by a tissue biopsy and reviewed at Hospital Moinhos de Vento, and your cancer is either HER2-positive (a specific prot...
NCT05327465 · Dana-Farber Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older (children under 18 are not eligible due to how rare this disease is in that age group) - People who have been diagnosed with prostate cancer (either localised or spread to other parts of the body), confirmed through a tissue sample - People who have be...
NCT05328505 · University Health Network, Toronto Not Applicable · 1 country
Who might be able to join this trial: - Men aged over 18 years old. - People with a confirmed diagnosis of prostate adenocarcinoma (a specific type of prostate cancer) proven through tissue testing. - People who have previously had their prostate removed through surgery (radical prostatectomy). - People whose cancer ha...
NCT05348876 · Bayer Phase 4 · 1 country
**Who might be able to join this trial:** - People who are able to give their signed agreement to take part in the study. - People who are male and aged 18 years or older. - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed by a tissue or cell sample, without certain rar...
NCT05350475 · University of Aarhus Not Applicable · 1 country
**Who might be able to join this trial:** - People with prostate cancer that has been confirmed by a tissue sample (biopsy), where the cancer is localised or locally advanced and has not spread to distant parts of the body (specific staging criteria apply — confirm with trial site) - People whose cancer type is adenoc...
NCT05352178 · Universitaire Ziekenhuizen KU Leuven Phase 3 · 1 country
**Who might be able to join this trial:** - A diagnosis of prostate cancer (adenocarcinoma type) confirmed by a tissue sample (biopsy). - The original prostate tumour has already been treated and is under control. - A rise in PSA (a prostate-related protein measured in the blood) after surgery to remove the prostate f...
NCT05354375 · The Affiliated Hospital of Xuzhou Medical University Phase 1 · 1 country
**Who might be able to join this trial:** - Men between 18 and 75 years old - People whose general physical condition is rated at a certain level of functioning (ECOG score of 2 or below — confirm with trial site) - People who have prostate cancer that has stopped responding to hormone-lowering treatments (castration-...
NCT05361798 · National Cancer Institute (NCI) Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with localised intermediate-risk or high-risk prostate cancer, confirmed through a tissue or cell sample test (intermediate-risk means a Gleason score of 7 and PSA under 10; high-risk means a Gleason score of 8–10, PSA over 10, or cancer that has gr...
NCT05381103 · Five Eleven Pharma, Inc. Phase 3 · 1 country
Who might be able to join this trial: - People diagnosed with prostate cancer that meets certain severity levels based on how the cancer cells look under a microscope (called a Gleason score), ranging from moderately aggressive to highly aggressive (confirm with trial site for exact score requirements) - People who cur...
NCT05396872 · University of California, San Francisco Not Applicable · 1 country
Who might be able to join this trial: **Patients (Stage 1):** - Adults aged 18 or older - Able to understand and follow the study procedures for the full duration of the study - Able to understand and willing to sign a written consent form - Able to speak, read, and understand English - Has a confirmed diagnosis of lo...
NCT05398302 · Jonsson Comprehensive Cancer Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who have prostate cancer that has been confirmed through laboratory testing of tissue samples - People whose cancer has been determined eligible for a specific treatment called 177Lu-PSMA-617, either through a special access program or as part of an approved trial - P...
NCT05403177 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with a blood cancer or a solid tumor (a growth/lump), confirmed by a lab test of a tissue or cell sample - If your type of cancer doesn't usually require a biopsy before surgery to confirm the diagnosis, you may still join, but your eligibility will b...
NCT05423860 · HALO Diagnostics Not Applicable · 1 country
**Who might be able to join this trial:** - Men who are 45 years of age or older. - People who have been diagnosed with a specific type of prostate cancer called prostate adenocarcinoma. - People whose cancer has been classified at an early stage (T1c or T2a). - People whose cancer has a Gleason score (a measure of ho...
NCT05438563 · Mayo Clinic Not Applicable · 1 country
**Who might be able to join this trial:** - You are male and between 45 and 80 years old, with an expected life expectancy of more than 10 years - You have been diagnosed with intermediate-risk prostate cancer, confirmed by a biopsy, falling into specific risk categories (confirm with trial site) - Your cancer has not...
NCT05443412 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older - People where doctors suspect prostate cancer may be present - People with a prostate-specific antigen (PSA) blood test result between 4 and 20 ng/mL - People whose rectal examination results suggest the cancer, if present, appears to be contained within the...
NCT05448547 · Sven Löffeler Phase 3 · 4 countries
**Who might be able to join this trial:** - People who are 75 years of age or older at the time of signing the consent form - People who are considered healthy or only mildly frail based on a medical check-up and two standard geriatric assessments (called G8 and miniCOG™), which measure overall health and thinking abi...
NCT05454488 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You are a male adult who speaks English - Your doctor believes you are expected to live for more than 10 years - You have had an MRI-guided biopsy of a visible area on your prostate MRI before joining the trial (including additional biopsy samples taken in a standard pattern...
NCT05478694 · University of Texas Southwestern Medical Center Not Applicable · 1 country
Who might be able to join this trial: - Men who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed through a prostate biopsy - Men who have had prostate cancer come back in the same area (local recurrence), confirmed by biopsy and standard imaging tests that show the cancer has n...
NCT05487846 · Thomas Jefferson University Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to sign and date a consent form agreeing to take part in the study - People who speak English - People who are willing to follow all study procedures and are available for the full duration of the study - People who are 18 years of age or older - A...
NCT05488548 · Epigenetix, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - You have prostate cancer that has stopped responding to hormone therapy and has come back or not responded to at least one anti-androgen treatment and a chemotherapy regimen containing docetaxel. - You have a rare cancer called NUT midline carcinoma that has spread or cannot...
NCT05497024 · M.D. Anderson Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** *Patients:* - Men aged 65 or older - People who have been diagnosed with localised prostate cancer (cancer that has not spread beyond the prostate) - People who have been on an active surveillance program for their prostate cancer for 12 months or more - People who are fluent...
NCT05520255 · University of Alberta Phase 3 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who have had their prostate removed (radical prostatectomy) for prostate cancer, and whose PSA blood test result is 0.2 mcg/L or higher - Adults aged 18 or older who have had radiation therapy, cryotherapy, or brachytherapy for prostate cancer, and wh...
NCT05530655 · University of Rochester Early Phase 1 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) and are scheduled to receive external beam radiation therapy, possibly with or without hormone therapy, at the Wilmot Cancer Institute Department of Radiation Oncology - Your cancer has not...
NCT05534646 · Edwin Posadas, MD Phase 2 · 1 country
**Who might be able to join this trial:** - People who have prostate cancer that has stopped responding to hormone therapy (called castration-resistant prostate cancer) and whose PSA levels are rising while taking one of these specific medications: abiraterone, enzalutamide, or darolutamide. - People who have previous...
NCT05539677 · N.N. Petrov National Medical Research Center of Oncology Not Applicable · 1 country
**Who might be able to join this trial:** - People who have signed an informed consent form agreeing to take part - People whose tumour has been confirmed by laboratory testing of a tissue sample - People who are currently receiving a treatment that works throughout the body (such as chemotherapy or similar) for their...
NCT05549024 · Peking Union Medical College Hospital Early Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with, or are suspected to have, breast, brain, or prostate cancer - People who are able to undergo specific PET/CT scans (using 68Ga-RM26-RGD and 18F-FDG, or related imaging agents) within a 2-week period (confirm with trial site for details on whic...
NCT05558007 · Biozeus Biopharmaceutical S.A. Phase 2 · 1 country
**Who might be able to join this trial:** - Men between the ages of 40 and 65 years - Men who identify as exclusively heterosexual, regardless of race or social background - Men who had their prostate removed (radical prostatectomy, or RP) as treatment for prostate cancer that had not spread to other parts of the body...
NCT05563558 · Fundacion Oncosur Phase 2 · 1 country
**Who might be able to join this trial:** - People who are male and at least 18 years old at the time of signing the consent form - People who have been diagnosed with a type of prostate cancer called adenocarcinoma and/or neuroendocrine carcinoma, confirmed through a tissue sample examination - People whose cancer ha...
NCT05568550 · Zin W Myint Phase 2 · 1 country
**Who might be able to join this trial:** - Male patients who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed through a tissue test - People whose prostate cancer is classified as high-risk or very high-risk according to standard medical guidelines (called NCCN guidelines...
NCT05574647 · Imperial College London Not Applicable · 1 country
**Who might be able to join this trial:** **First stage (initial scan):** - You are 18 years of age or older (there is no upper age limit) - You have a prostate (this includes men born male, or transgender women who have never used hormone therapy to reduce testosterone) - Your doctor has referred you for a prostate M...
NCT05582772 · University Health Network, Toronto Not Applicable · 1 country
Who might be able to join this trial: - People who are starting, or have recently started (within the last 2 weeks), a type of prostate cancer hormone therapy called an androgen receptor axis-targeted therapy (ARAT), or who are switching to a different ARAT because their previous one stopped working or caused side effe...
NCT05582876 · Medical University of Bialystok Not Applicable · 1 country
**Who might be able to join this trial:** **Group 1 – Newly diagnosed prostate cancer (before treatment):** - You have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - Your cancer has been classified as medium or high risk based on specific scoring systems used by doctors (Gleason score, can...
NCT05590624 · Case Comprehensive Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - Men whose urologist strongly suspects they may have prostate cancer, based on clinical assessment - Men with a BMI greater than 18.5 - Men who have not previously been diagnosed with prostate cancer or received hormonal therapy for it - Men who are abl...
NCT05593497 · VA Office of Research and Development Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older, of any race or ethnic background - People who have signed a consent form agreeing to take part and follow the study requirements - People who have been confirmed through a tissue test (biopsy) to have prostate cancer that has not spre...
NCT05597852 · Sunnybrook Health Sciences Centre Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with locally returning prostate cancer, confirmed by both tissue biopsy and imaging scans - People who are willing to give their agreement to take part in this clinical trial - People who are able and willing to fill out two health-related quest...
NCT05600400 · Sunnybrook Health Sciences Centre Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by a tissue sample reviewed by a central laboratory) - People whose prostate cancer is classified as "low risk" — meaning the cancer is at an early, localised stage (T1–T2b)...
NCT05603559 · Peking Union Medical College Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have prostate cancer that has spread to other parts of the body, is no longer responding to hormone-suppressing treatments and/or chemotherapy, and is getting worse over time. - People whose cancer has been confirmed by a specific type of scan (called a 68Ga-PSMA P...
NCT05608694 · University of Chicago Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 or older - People with no known history of prostate cancer - People who have not previously had prostate surgery or tissue removal procedures (such as TURP or photovaporization) Who may not be able to join: - People who are unable to have an MRI s...
NCT05613738 · Peking Union Medical College Hospital Not Applicable · 1 country
Who might be able to join this trial: - You have prostate cancer that has spread to other parts of the body, is getting worse, and is no longer responding to hormone therapy. - Your tumors show high levels of a protein called PSMA, confirmed by a special type of scan called a 68Ga-PSMA PET/CT scan. Who may not be able...
NCT05616650 · National Cancer Institute (NCI) Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with low or intermediate risk prostate cancer, confirmed by a tissue sample (biopsy), with the diagnosis verified by the NIH Laboratory of Pathology. - People whose prostate cancer appears in only one single spot, as seen on both MRI and a spec...
NCT05629494 · Albany Medical College Phase 4 · 1 country
**Who might be able to join this trial:** - Men between 18 and 80 years old whose PSA blood test result is above 3 ng/ml and who are being considered for further testing such as an MRI or prostate biopsy - Men who have had a normal prostate exam (done by a doctor feeling the prostate through the rectum) within the pas...
NCT05647564 · University of Wisconsin, Madison Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma, confirmed by a tissue test). - People who have at least one sign of cancer that has spread, visible on a CT scan or bone scan. - People whose prostate cancer is getting worse, shown b...
NCT05649943 · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano Not Applicable · 1 country
**Who might be able to join this trial:** - You must be over 18 years old. - You must have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a tissue sample (biopsy). - Your cancer must have spread to at least one area in the bones, confirmed by a special bone scan; if only...
NCT05652686 · Phanes Therapeutics Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older who are able to give written consent and follow the study requirements - People whose cancer can be measured using standard imaging criteria (known as RECIST v1.1) - People with a confirmed diagnosis of small cell lung cancer (SCLC), large cell neuroe...
NCT05656573 · Nova Therapeutics LLC Phase 1 · 1 country
**Who might be able to join this trial:** - People who are able to understand and are willing to sign a written consent form agreeing to participate - People who have been diagnosed with prostate cancer confirmed by a tissue sample - People whose cancer cells produce a protein called PSMA, confirmed by laboratory test...
NCT05665738 · University of California, San Francisco Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (adenocarcinoma type), confirmed by a tissue or cell sample. - Your prostate cancer is classified as low to intermediate risk according to standard cancer guidelines. - You have not received any previous treatment for prostate canc...
NCT05672485 · First Affiliated Hospital Xi'an Jiaotong University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who are highly suspected of having prostate cancer based on one or more of the following: a notable rise in their PSA blood test results over time (specific thresholds apply depending on their PSA level); a close family member (parent, siblin...
NCT05691465 · National Cancer Institute (NCI) Phase 2 · 1 country
**Who might be able to join this trial:** - You have prostate cancer that has spread (metastatic) and shows signs of a specific type called neuroendocrine prostate cancer, confirmed by biopsy, blood tests, or certain molecular features - You are 18 years of age or older (there is no upper age limit) - You are well eno...
NCT05698576 · Urological Research Network, LLC Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written informed consent to participate - People who are able and willing to attend all required procedures and follow-up visits as set out in the study plan - People who do not have urinary retention (the inability to empty the bladde...
NCT05710380 · University of Chicago Not Applicable · 1 country
Who might be able to join this trial: - People with known or suspected prostate cancer who have been referred for a prostate MRI scan, to be followed by a type of biopsy that uses MRI imaging as a guide. - People who are willing and able to give written consent to take part before the MRI scan takes place. Who may not...
NCT05714774 · Hospices Civils de Lyon Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been fully informed about the study and have agreed to take part by signing a consent form, after having enough time to think it over. - Men aged 50 years or older. - People whose PSA blood test result is 15 ng/mL or below. - People who have been diagnosed wi...
NCT05715502 · The Greater Poland Cancer Centre Not Applicable · 1 country
**Who might be able to join this trial:** - People who have had prostate cancer come back after previous radiation treatment (such as brachytherapy, external beam radiotherapy, or stereotactic radiotherapy), confirmed by a biopsy - People whose cancer has been assessed by MRI scan (or ultrasound and CT scan if MRI is n...
NCT05722392 · Sun Yat-sen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a prostate biopsy - People whose cancer has been assessed by imaging scans as being contained within the prostate (not spread to other areas) - People whose prostate is larger than 70mL in size, as measured by ultra...
NCT05726292 · University of Chicago Phase 2 · 1 country
**Who might be able to join this trial:** - A diagnosis of prostate cancer (adenocarcinoma type) confirmed by a tissue or cell sample, without a small cell type. - The cancer must be localised (contained to the prostate area), with a surgeon confirming it can be removed by surgery before joining. - No signs of cancer...
NCT05739565 · Centre Hospitalier Universitaire de Saint Etienne Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with prostate cancer for at least one year - People who currently do less than 150 minutes of physical activity per week (which the World Health Organization considers inactive) - People who are covered by a social secu...
NCT05740956 · Jiangsu Hansoh Pharmaceutical Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - Adults between 18 and 75 years old (inclusive) - People who have at least one measurable area of cancer that can be tracked during the trial - People in the Phase Ia part (Cohort A): those with an advanced solid tumour that has a specific DNA repair gene change (called an HR...
NCT05745844 · GCS Ramsay Santé pour l'Enseignement et la Recherche Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been receiving medication to lower androgen (male hormone) levels as treatment for prostate cancer for more than 26 weeks. - People who are fully active or have only minor limitations in daily physical activity (based on a standard health performance scale sco...
NCT05753566 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medic... Phase 2 · 1 country
**Who might be able to join this trial:** - People who are male and aged 40 or older - People who have been diagnosed with prostate cancer (adenocarcinoma type), confirmed by a tissue test - People whose lymph nodes were found to be cancer-free, or whose lymph nodes could not be fully assessed, at the time of surgery...
NCT05754580 · University of Nebraska Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by tissue testing, classified as unfavorable intermediate risk or higher risk according to standard medical guidelines (NCCN criteria). - People who have not yet received any definitive treatment for their prostat...
NCT05754658 · Fox Chase Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 to 85 years old who have been diagnosed with cancer (of any type or stage), confirmed by a medical test such as a biopsy. - Both men and women are eligible. - People who have had a previous cancer diagnosis in the past may also be eligible, as this will be taken in...
NCT05762198 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 50 and 80 years of age - People whose urinary retention (inability to pass urine) has not improved with standard treatments and is caused by a condition called benign prostatic hyperplasia (BPH), which is a non-cancerous enlargement of the prostate gland - People...
NCT05766371 · University of California, San Francisco Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) that has spread to other parts of the body, is no longer responding to hormone-lowering treatments, and is getting worse over time. - People who are male and are at least 18 years...
NCT05767307 · Aarhus University Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who can understand spoken and written Danish - People who have been referred for an MRI scan (either a full multi-parametric or a bi-parametric type) due to a suspicion of prostate cancer at one of three specific hospitals: Aar...
NCT05781217 · Instituto de Investigación en Oncología Radioterápica - Fundación Espa... Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy and have had their prostate surgically removed (radical prostatectomy), including those who did not have lymph nodes removed during that surgery. - People whose PSA blood test levels have risen...
NCT05786742 · CHU de Quebec-Universite Laval Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a biopsy, specifically a type called adenocarcinoma - People whose cancer is at an early stage (T1c or T2), meaning it is contained within or just around the prostate - People whose cancer has not been found in...
NCT05790213 · University of Chicago Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with intermediate-risk prostate cancer, either "favorable" or "unfavorable" type, based on specific measurements of cancer stage, cancer grade (Grade Group 2 or 3), PSA level, and how many biopsy samples contained cancer cells. - People whose MRI scan shows...
NCT05792722 · Johns Hopkins University Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with bladder cancer (confirmed by a lab test) and are scheduled to have your bladder surgically removed - Unusual or rare types of bladder cancer are also allowed - Having received treatment (such as chemotherapy) before surgery is allowed - You are ov...
NCT05802121 · Western University Early Phase 1 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has spread to other parts of the body and is planned to be treated with hormone-blocking therapy (called ADT) - People who have had recent imaging of the body, eithe...
NCT05803941 · Novartis Pharmaceuticals Phase 4 · 11 countries
Who might be able to join this trial: - The person must have agreed to take part by signing a consent form before joining the study. - The person must have already received at least one dose of a treatment called AAA617 as part of a separate Novartis-sponsored clinical trial (Phase I through IV) for prostate cancer, an...
NCT05805371 · City of Hope Medical Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have given written consent to take part (or whose legal representative has done so on their behalf). - People who agree to allow stored tumour tissue samples from a previous biopsy to be used for research purposes. - Peop...
NCT05806515 · SWOG Cancer Research Network Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue biopsy. - Your cancer is considered high or very high risk, meaning at least one of the following applies: the tumor has grown into nearby tissue (cT3a–cT4), your...
NCT05810467 · Institute of Cancer Research, United Kingdom Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older who are currently being monitored through an Active Surveillance clinic for prostate cancer. - Men who have been diagnosed with prostate cancer and whose medical team has agreed at a specialist group meeting that Active Surveillance (monitoring rather than im...
NCT05838716 · University of Rochester Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with Stage I to Stage IV prostate cancer that has not spread to the bones (involvement of lymph nodes is allowed, and a previous diagnosis of another cancer is also allowed) - People aged 50 years or older - People who are about to start, or ha...
NCT05847166 · NCBJ Polatom: Narodowe Centrum Badań Jądrowych Polatom Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People whose general health and ability to carry out daily activities meets a certain minimum level, as assessed by a standard medical scale called the ECOG Performance Status (score must be below 2) (confirm with trial site) - People who have alrea...
NCT05850182 · Oncology Institute of Southern Switzerland Not Applicable · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form before registering for the trial - People aged 18 years or older - People whose prostate cancer has been confirmed by biopsy or tissue testing to be a type called adenocarcinoma - People with prostate cancer who are currently rece...
NCT05851547 · Ottawa Hospital Research Institute Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) showing a specific type called adenocarcinoma - Your cancer is classified as either "unfavourable intermediate-risk" or "high-risk" localised prostate cancer (meaning it has not spread beyond...
NCT05864196 · NYU Langone Health Phase 1 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with a specific type of prostate cancer called adenocarcinoma that is contained within the prostate (localized) - People whose prostate cancer diagnosis has been confirmed through a biopsy - People whose cancer is clas...
NCT05869682 · City of Hope Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a laboratory test of tissue or cells - People who have measurable signs of the disease visible on a CT scan, MRI, bone scan, or a specialised PET scan (such as Axumin or PSMA-PET) - People whose doctor has plan...
NCT05879913 · Indiana University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are able to provide written consent and agree to the release of their personal health information - People who are 40 years of age or older at the time of joining - People who have been diagnosed with prostate cancer and are either currently receiving hormone ther...
NCT05888532 · Rahul Aggarwal Phase 2 · 1 country
**Who might be able to join this trial:** - People with a confirmed diagnosis of a solid tumour cancer that has spread (metastatic) or is locally advanced, as seen on standard imaging scans — the specific cancer type depends on which group (cohort) a person is being considered for: - **Group A:** Any metastatic soli...
NCT05893381 · Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. I... Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with prostate cancer that has spread to 1 to 3 areas in the body (with no symptoms from those spread areas), where each affected area is no larger than 5.0 cm or 250 cm³, confirmed by a CT, MRI, or whole-body MRI scan. - People whose PSMA-PET/CT scan (a spec...
NCT05912764 · GCS Ramsay Santé pour l'Enseignement et la Recherche Not Applicable · 1 country
**Who might be able to join this trial:** - People who are scheduled to have a laser procedure through a scope to remove excess prostate tissue - People with an enlarged prostate causing bothersome symptoms that have not improved with medication - People with an enlarged prostate that has led to the inability to fully...
NCT05918263 · Fred Hutchinson Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with localised prostate cancer (cancer that has not spread beyond the prostate), confirmed by a tissue sample test - People who are currently on active surveillance (monitoring the cancer rather than treating it immedia...
NCT05919329 · OHSU Knight Cancer Institute Phase 4 · 1 country
**Who might be able to join this trial:** - The participant, or their legal representative, must be willing and able to provide written consent before any study procedures begin. - A confirmed diagnosis of prostate adenocarcinoma (a type of prostate cancer) is required, confirmed through tissue testing or a combinatio...
NCT05923684 · Cedars-Sinai Medical Center Not Applicable · 1 country
Who might be able to join this trial: - Men attending their first treatment consultation for prostate cancer that has not spread beyond the prostate - Men who were on an active monitoring program for prostate cancer and whose cancer has been found to have progressed, and who are now considering switching to a more acti...
NCT05931419 · Comprehensive Cancer Centre The Netherlands Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a new (not previously treated) high-risk prostate cancer that has not spread to other parts of the body, confirmed by a tissue sample (biopsy) - People whose cancer meets at least one of the following high-risk features: the tumour has gro...
NCT05933876 · Institut Investigacio Sanitaria Pere Virgili Not Applicable · 1 country
Who might be able to join this trial: - People whose cancer started in the breast, prostate, lung, or bowel (colorectal), confirmed by a tissue test (biopsy). - People aged 18 or older. - People who have up to five areas where cancer has spread (metastases), located in the bones, lungs, lymph nodes, liver, or brain. -...
NCT05936736 · IRCCS San Raffaele Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a type called adenocarcinoma), confirmed by a tissue biopsy, across a range of grades from low to high - People who are over 18 years of age - People who have signed a consent form agreeing to take part in the trial - Peop...
NCT05940259 · Peking University First Hospital Not Applicable · 1 country
"Who might be able to join this trial: - People who have been diagnosed with cancer, or where cancer is suspected but not yet confirmed. - People who have signed a written informed consent form agreeing to take part in the trial. Who may not be able to join: - No exclusion criteria have been listed for this trial (con...
NCT05942001 · Jiangsu HengRui Medicine Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent to participate. - People aged between 18 and 80 years old, of any gender. - People whose general physical functioning is rated as fully active or restricted only in strenuous activity (as measured by a standard medical s...
NCT05946213 · NRG Oncology Phase 3 · 4 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue or cell sample from a biopsy - People whose cancer is considered "high-risk" based on at least one of the following: the tumour has grown to a certain size...
NCT05956639 · The First Affiliated Hospital with Nanjing Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 or older. - People whose general health and ability to carry out daily activities meets a standard level (rated 0 or 1 on a scale used by doctors to measure this). - People who have been confirmed through lab testing of tissue or cells to have...
NCT05958082 · Henry Ford Health System Not Applicable · 1 country
**Who might be able to join this trial:** - You are a man aged 18 or older. - You racially identify as Black, or as multiracial including Black. - You have been diagnosed with prostate cancer of any type. - You have low-risk or intermediate-risk prostate cancer AND have a relevant family history — meaning a father, br...
NCT05965180 · University of Michigan Rogel Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - A prostate biopsy is already planned as part of the person's regular medical care. - The person is between 41 and 79 years old. Who may not be able to join: - The person has a known history of bleeding disorders. - The person is currently taking blood-thinning medications (antic...
NCT05975775 · GCS Ramsay Santé pour l'Enseignement et la Recherche Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 or older - People who have been diagnosed with prostate cancer that has not spread beyond the prostate (localised prostate cancer) - People whose case has been reviewed and approved for curative (aimed at curing) treatment by a multidisciplinary me...
NCT05983783 · The First Affiliated Hospital with Nanjing Medical University Phase 3 · 1 country
**Who might be able to join this trial:** - Men between 40 and 80 years of age - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue or cell sample - People whose prostate cancer has spread to other parts of the body (metastatic disease) - People...
NCT06001255 · Hansoh BioMedical R&D Company Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - People with locally advanced or spreading (metastatic) solid tumour cancers that have been confirmed by laboratory testing, where standard treatments have stopped working, are not available, or caused intolerable side effects - People who have at le...
NCT06001619 · Turku University Hospital Phase 4 · 1 country
Who might be able to join this trial: - People who have signed and dated a consent form agreeing to take part. - People who are able and willing to follow all study procedures and are available for the full duration of the study. Who may not be able to join: - People who have ever had a fecal (stool) transplant. - Peo...
NCT06014255 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (adenocarcinoma type) confirmed by a tissue sample, where the cancer is at an early-to-locally advanced stage and has not spread to the lymph nodes, bones, or other organs — though a small number of lymph node findings on a...
NCT06022822 · National Cancer Institute (NCI) Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a laboratory test on tissue samples, including those whose cancer is being monitored without immediate treatment (called active surveillance) — a biopsy taken within th...
NCT06027892 · Rabin Medical Center Not Applicable · 1 country
**Who might be able to join this trial:** - You are male and at least 18 years old - You have been diagnosed with low-risk or "favorable intermediate-risk" prostate cancer (a specific, less aggressive form of prostate cancer) - Your cancer is at an early stage, has not spread widely in the prostate, and your PSA (a pro...
NCT06029036 · Peking University First Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - You are male and at least 18 years old - You are able to sign a consent form on your own, without assistance - You have been diagnosed with prostate cancer (specifically adenocarcinoma) that has not spread to distant parts of the body - Your cancer is considered "high-risk,"...
NCT06031805 · AstraZeneca Not Applicable · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 or older - People who have prostate cancer that has spread to other parts of the body and is no longer responding to hormone-lowering treatment - People who have started taking a medication called olaparib within at least the last two months b...
NCT06037954 · Memorial Sloan Kettering Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** *For patients:* - People who have been diagnosed with breast, colorectal, lung, or prostate cancer at age 65 or older, based on medical records or their own report - People who are currently receiving cancer treatment (such as radiation, chemotherapy, immunotherapy, or surgery...
NCT06039085 · Ryan J. Halter Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer and need a type of robotic surgery to remove the prostate (called robot-assisted radical prostatectomy) - People who are able to understand the study information and are willing to sign a written consent form agreeing to take pa...
NCT06039371 · University of Washington Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to give written consent before any study-related procedures begin - People aged 18 or older - People who have been diagnosed with prostate cancer (adenocarcinoma type), confirmed by a tissue sample - People whose prostate cancer has stopped responding...
NCT06040125 · Dana-Farber Cancer Institute Not Applicable · 1 country
Who might be able to join this trial: - People who are able to understand and are willing to sign a consent form before any study procedures begin. - People who have been diagnosed with prostate cancer that has spread to other parts of the body (metastatic prostate cancer). - People who are aged 18 or older. - People w...
NCT06044025 · University of Arkansas Phase 1 · 1 country
Who might be able to join this trial: - People aged 18 or older. - People who have previously had their prostate removed (prostatectomy) and/or received radiation treatment to the prostate. - People whose PSA level is rising — specifically at or above 0.2 ng/ml after prostate removal, or at least 2 points above their l...
NCT06044857 · University of Texas Southwestern Medical Center Phase 1 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (confirmed by a tissue sample within the last 180 days) that is considered "high risk" based on at least one of the following: the cancer has spread to certain nearby tissues (stage cT3a or higher), your PSA level is above 20 ng/m...
NCT06046040 · University of Pennsylvania Phase 1 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form agreeing to take part in the study - Adults aged 18 or older - People who have prostate cancer that has spread to other parts of the body and is no longer responding to hormone-lowering treatments (known as metastatic castrate-re...
NCT06046131 · Centre Hospitalier Universitaire de la Guadeloupe Not Applicable · 2 countries
**Who might be able to join this trial:** - Adults who have recently been diagnosed with prostate cancer (a new, first-time diagnosis) - People who attend appointments at either the University Hospital of Guadeloupe or the University Hospital of Rennes - People who live in Guadeloupe, Martinique, the community of Saint...
NCT06052683 · CHU de Quebec-Universite Laval Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been confirmed by biopsy to have prostate adenocarcinoma (a specific type of prostate cancer) diagnosed within the last 8 months — including people on active surveillance whose cancer has shown signs of progression and who have had a recent biopsy within 8 mo...
NCT06059118 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a tissue sample. - People whose cancer has spread to other parts of the body, as shown on a CT scan or bone scan. - People...
NCT06059859 · European Institute of Oncology Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically adenocarcinoma, confirmed by biopsy) that has not yet been treated - People aged 18 years or older - People whose prostate cancer is classified as low or intermediate risk based on European guidelines, meaning thei...
NCT06064149 · Vivek Narayan Not Applicable · 1 country
Who might be able to join this trial: - Men over 18 years old who have prostate cancer and are currently receiving, or are about to receive, at least 6 months of hormone-blocking treatment (called ADT) - People who are able to read and understand English Who may not be able to join: - No specific exclusion criteria ha...
NCT06067269 · Jonsson Comprehensive Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) - You are 18 years of age or older - Your prostate cancer has been classified as "unfavorable intermediate risk" based on specific combinations of your PSA level, tumor stage, and biopsy...
NCT06067295 · University of Southern California Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older, of any racial or ethnic background - Men who have been diagnosed with advanced (spread) prostate cancer and are about to start a new round of treatment (whether it is their first treatment or a later one) - Men who have previously taken part in other clinica...
NCT06067841 · Bristol-Myers Squibb Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically the type called adenocarcinoma), confirmed through a tissue or cell sample. - People who are generally able to carry out daily activities with no or minimal limitations (based on a standard medical scale called ECO...
NCT06072911 · University of Alberta Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer at any stage (stage I to IV) - People who are scheduled to have surgery to remove the prostate (any surgical method) - People who have no restrictions on doing at least light physical activity, based on a standard health screeni...
NCT06084338 · VA Office of Research and Development Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older at the time they sign the consent form - People who are willing and able to give written consent to participate (or have a legal representative do so on their behalf) - People who have been diagnosed with prostate cancer of a specific...
NCT06085664 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - People who have been diagnosed with a specific high-grade prostate cancer (Gleason score of 8 or higher), confirmed by a biopsy showing cancer in at least 3 tissue samples, with at least one sample containing 8 mm or more of high-grade cancer — and the...
NCT06085729 · M.D. Anderson Cancer Center Phase 2 · 1 country
Who might be able to join this trial: - People who have signed an informed consent form before any study procedures begin. - People who agree to have tissue samples collected at specific points during the study. - People who agree to a specific laboratory research protocol used at MD Anderson (PA13-0291). - Men aged 18...
NCT06099093 · Brigham and Women's Hospital Phase 4 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a laboratory test on tissue or cell samples. - People who are 18 years of age or older. - People who are already planned to receive a standard treatment called 177Lu-Vipivotide Tetraxetan following a specific ty...
NCT06100705 · Yale University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent before any study procedures begin. - People whose prostate cancer meets the US FDA-approved criteria for a treatment called Sipuleucel-T — meaning the cancer causes no symptoms or only mild symptoms, as determined by th...
NCT06101290 · University of California, Davis Not Applicable · 1 country
Who might be able to join this trial: - People who have been confirmed by lab testing to have one of three types of cancer: prostate cancer (Cohort A), urothelial carcinoma — a cancer of the bladder or urinary tract (Cohort B), or renal cell carcinoma — a type of kidney cancer (Cohort C). - People who are willing and a...
NCT06111313 · University of Miami Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with a type of prostate cancer called adenocarcinoma (including intraductal adenocarcinoma), confirmed by a biopsy — small cell carcinoma is not included - People whose cancer is classified as stage T1, T2, or T3 based on a physical examination and...
NCT06111781 · Yale University Phase 2 · 1 country
**Who might be able to join this trial:** - You are willing to sign a consent form and take part in all parts of the study for its full duration - You have been diagnosed with prostate cancer (adenocarcinoma) confirmed by a tissue or cell sample - You were assigned male at birth and are 18 years of age or older (trans...
NCT06112990 · University of Utah Phase 3 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have prostate cancer that has spread to other parts of the body (metastatic) and is still responding to hormone-lowering treatment, with no signs of the disease getting worse according to standard prostate cancer guidelin...
NCT06117059 · NHS Lothian Not Applicable · 1 country
Who might be able to join this trial: - People diagnosed with low-risk or "favorable intermediate-risk" prostate cancer, based on standard cancer risk guidelines - People whose prostate gland is smaller than 80cc in size - People with a urinary symptom score (IPSS) below 20, meaning relatively mild to moderate urinary...
NCT06126731 · Institute of Cancer Research, United Kingdom Phase 2 · 2 countries
Who might be able to join this trial: - People who have been confirmed by laboratory testing to have metastatic castration-resistant prostate cancer or a related form that has stopped responding to standard treatment, or for whom no standard treatment is available or who have chosen not to pursue standard treatment. -...
NCT06130995 · University of Oklahoma Phase 1 · 1 country
**Who might be able to join this trial:** - People who are able to give their signed agreement to participate in the trial. - People who are 18 years of age or older at the time of signing the consent form. - Men who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a t...
NCT06134232 · Dendreon Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who have prostate cancer that has spread to other parts of the body, is no longer responding to hormone treatment, and causes no symptoms or only mild symptoms. - Men whose doctors have determined they are appropriate candidates for treatment with PROVEN...
NCT06138067 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years old or older - You must currently have a diagnosis of a primary solid tumor, specifically prostate cancer or kidney cancer - You must be receiving care at the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins University or at a Wellspan Healt...
NCT06141993 · Duke University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue biopsy — those with a pure small cell or neuroendocrine type of prostate tumour are not included - People who have imaging scans (CT, MRI, or PET) showing...
NCT06145633 · Fred Hutchinson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (adenocarcinoma type), confirmed by a tissue biopsy. - Your prostate cancer has continued to grow or spread even though your testosterone levels are very low (a stage called "castration-resistant prostate cancer"), shown by rising...
NCT06150417 · Case Comprehensive Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older. - People whose overall health and ability to carry out daily activities meets a certain fitness level (confirm with trial site). - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has sp...
NCT06155084 · Hinova Pharmaceuticals Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - You must be male and at least 18 years old - You must have a specific genetic change in your prostate cancer cells involving the androgen receptor (a protein that helps cancer grow) — this applies to the later stage of the trial (confirm with trial site) - Your prostate canc...
NCT06161506 · National Cancer Institute (NCI) Phase 2 · 1 country
**Who might be able to join this trial:** - Participants must be male. - Participants must have had urinary leakage or loss of bladder control for at least 6 months after receiving treatment for prostate cancer (such as surgery or radiation). - Participants must experience at least one of the following: leaking urine...
NCT06163924 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 18 and 80 years old - People who have been diagnosed with prostate cancer, either confirmed through a tissue sample (biopsy) or through clinical assessment by a doctor - People who are planned to receive hormone-blocking treatment (called ADT) for at least one yea...
NCT06165302 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not Applicable · 1 country
**Who might be able to join this trial:** - Men who have been diagnosed with metastatic prostate cancer (a type called adenocarcinoma, where the cancer has spread beyond the prostate) - People currently receiving hormone-blocking treatment (androgen deprivation therapy), either alone or combined with one of these medic...
NCT06171139 · University of California, San Francisco Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years old or older - You identify as Black or African American (including mixed-race with Black or African American heritage) — this can be based on your own self-report - You have been told you have prostate cancer that has spread to other parts of the body (meta...
NCT06172283 · State University of New York at Buffalo Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form agreeing to take part in the trial. - People who were male at birth and are at least 18 years old at the time of signing the consent form. - People who have measurable prostate cancer and whose condition makes the...
NCT06173362 · University of California, Davis Phase 2 · 1 country
**Who might be able to join this trial:** - You are able to understand and willing to sign a consent form agreeing to take part in the study - You have been diagnosed with prostate cancer (confirmed by a tissue sample/biopsy) - Your doctor has decided that your prostate cancer is advanced enough to be treated with one...
NCT06177093 · Sunnybrook Health Sciences Centre Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 years or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a tissue sample, where radical radiotherapy (a curative course of radiation treatment) is recommended - People whose cancer has a Gleason score of...
NCT06184464 · Consorci Sanitari de Terrassa Not Applicable · 1 country
Who might be able to join this trial: - Men who have had a prostate biopsy that came back positive for cancer - People who are able to read, understand, and sign a consent form agreeing to take part in the study - People whose treatment plan requires hormone therapy before starting radiation treatment Who may not be a...
NCT06190899 · Celcuity Inc Phase 2 · 4 countries
**Who might be able to join this trial:** - Men aged 18 years or older - People who have a confirmed diagnosis of prostate cancer (adenocarcinoma type), with less than 10% of a specific cell type called neuroendocrine cells, and no small cell component - People whose prostate cancer has spread to other parts of the bo...
NCT06200103 · Mayo Clinic Phase 2 · 1 country
**Who might be able to join this trial:** - People scheduled at Mayo Clinic Rochester to receive a treatment called 177Lu PSMA-617 (a type of radioligand therapy for prostate cancer) - People who have been diagnosed with prostate cancer that has spread to other parts of the body and is no longer responding to hormone...
NCT06200259 · Covenant Health Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People who have had a physical examination and health history review to determine how far the cancer has spread - People whose cancer is at an early local stage (T1 to T2c based on a stand...
NCT06201078 · Maria Sklodowska-Curie National Research Institute of Oncology Phase 2 · 1 country
**Who might be able to join this trial:** - People who have had prostate cancer come back in the same area after receiving radiation therapy as their main treatment, confirmed either by a biopsy and/or by consistent MRI and PSMA-PET scan results along with rising PSA levels - People whose original radiation treatment...
NCT06202248 · Alpha Tau Medical LTD. Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has come back in the prostate (after previous treatment), confirmed by a tissue biopsy, and where the cancer is limited to at least one side of the prostate, with matching biopsy and scan results from within the last 6...
NCT06204341 · Haaglanden Medical Centre Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older who have been diagnosed with high-risk prostate cancer within the last 6 months - The cancer must meet at least one of these high-risk features: a tumour that has grown beyond the prostate (found during a physical exam), an aggressive cancer grade (Grade 4 or...
NCT06205316 · Mayo Clinic Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been confirmed by laboratory testing to have prostate adenocarcinoma (a specific type of prostate cancer) at the time of their surgery - People whose cancer was found to be at certain stages (T2 through T3b, with specific lymph node and spread classifications...
NCT06215508 · University of Chicago Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma of the prostate) confirmed by a tissue or cell sample, without certain rare cell types present. - People whose cancer has spread (metastasised) to at least one other part of the body, as seen o...
NCT06217822 · Bayer Phase 1 · 10 countries
**Who might be able to join this trial:** - People diagnosed with metastatic castration-resistant prostate cancer (a form of prostate cancer that has spread and no longer responds to hormone-lowering treatment), confirmed by a lab test to be a specific type called adenocarcinoma, without certain aggressive features (c...
NCT06219746 · Turku University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to give written consent and follow the study requirements - People who are male and aged 18 or older at the start of the study - People who have been diagnosed with high-risk prostate cancer confirmed by a tissue sample, meeting at least one of the...
NCT06220188 · Medical University of Vienna Phase 2 · 1 country
Who might be able to join this trial: - People with prostate cancer whose PSA levels are rising after both surgical removal of the prostate and radiotherapy, with PSA levels doubling within 12 months or less. - People who have not had hormone therapy in the past 12 months, or whose testosterone levels have returned to...
NCT06236139 · Fred Hutchinson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - A tissue sample (biopsy) has confirmed a diagnosis of prostate adenocarcinoma (a specific type of prostate cancer). - The cancer is detectable either through standard imaging measurements or through bone-only spread with a PSA blood level of at least 1 ng/mL. - The cancer ha...
NCT06236789 · Yonsei University Not Applicable · 1 country
Who might be able to join this trial: - Adults who are male and aged 19 years or older - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People whose prostate cancer has continued to grow despite hormone-reducing treatment (known as castration-resistant prostate cancer) - Peo...
NCT06237179 · Virginia Commonwealth University Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with stage II, III, or IV prostate cancer - People who are currently receiving androgen deprivation therapy (ADT), whether taken on and off or continuously - People who have already completed a primary treatment aimed at curing the cancer, such as s...
NCT06238713 · Shanghai Changzheng Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 18 and 75 years of age - People who have had a prostate biopsy within the last 6 months that confirmed prostate cancer that has not spread beyond the prostate, with a cancer stage of T1c to T2b, N0M0 - People whose cancer has a Gleason Score (a measure of cancer...
NCT06241846 · MediLink Therapeutics (Suzhou) Co., Ltd. Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand the study information and are willing to sign a consent form before the study begins. - People aged 18 or older. - People who have been diagnosed with prostate cancer confirmed by a tissue or cell sample, where the main cancer type found on...
NCT06242119 · Jagiellonian University Not Applicable · 1 country
Who might be able to join this trial: - People who have been referred by their doctor for a PET/CT scan to examine the whole body, for an accepted medical reason - People who are over 18 years of age - People who have given their free and informed agreement to take part in the study Who may not be able to join: - Peop...
NCT06242509 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older at the time of joining the trial - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue or cell sample - People whose prostate cancer has spread to other parts of the body and is no lo...
NCT06244004 · Northwestern University Phase 2 · 1 country
Who might be able to join this trial: - People who have prostate cancer that has spread to other parts of the body, confirmed by CT scan, MRI, and/or bone scan (even if those spread areas are no longer visible on scans after starting hormone therapy, as long as they were visible before hormone therapy began). - People...
NCT06249750 · Pengyuan Liu Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer, confirmed by a tissue/biopsy test, and your cancer has stopped responding to hormone therapy (known as castration-resistant prostate cancer) - You have complete and reliable medical records available - You do not have any other pr...
NCT06259123 · Medical University of Vienna Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with oligometastatic prostate cancer (cancer that has spread to a limited number of sites) detected by a specific type of scan called a PSMA PET scan, with no more than 5 bone metastases and/or no more than 3 lung metastases - People who are gen...
NCT06262139 · Songqi Gao Phase 2 · 1 country
**Who might be able to join this trial:** - You are male and over 18 years old. - You have been diagnosed with high-grade prostate cancer (Gleason score 8–10), confirmed by at least one specialist MRI scan and one prostate biopsy. - You are able to lie still for an MRI scan. - You are able and willing to sign a written...
NCT06262633 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - Men between the ages of 45 and 75 years - People with a life expectancy of more than 10 years at the time of joining the trial - People who are able to understand the trial and can provide signed, written consent before enrolling or completing any trial-related tests - Peopl...
NCT06273345 · Istituto Oncologico Veneto IRCCS Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been recently diagnosed with prostate cancer for the first time (any level of risk) - People whose prostate cancer has been confirmed through a tissue sample (biopsy), showing a specific type of prostate cancer cell (not a rare type called neuroendocrine) - P...
NCT06274047 · M.D. Anderson Cancer Center Phase 3 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy or surgical specimen). - People whose PSA level is 0.1 or higher after having their prostate surgically removed. - People whose treating doctor has determined them to be a suitable candi...
NCT06274892 · University Health Network, Toronto Not Applicable · 1 country
Who might be able to join this trial: - People who have been clinically diagnosed with breast cancer or prostate cancer - People who are about to start a full course of radiation therapy (either as the main treatment or as a follow-up treatment) as an outpatient at Princess Margaret Cancer Centre - People who are able...
NCT06276465 · UNICANCER Phase 3 · 1 country
**Who might be able to join this trial:** - People who have signed a written informed consent form before any trial procedures begin (if someone is physically unable to sign, a trusted person of their choice may confirm consent in writing on their behalf) - People aged 18 years or older - People who have been diagnose...
NCT06282588 · Cancer Research Antwerp Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy (laboratory analysis of a tissue sample). - People whose prostate cancer is considered high-risk or locally advanced, meaning at least one of the following applies: a PSA blood test result above...
NCT06292897 · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer Who may not be able to join: - There are no specific exclusion criteria listed at this time (confirm with trial site) Important: Always verify eligibility with the trial site directly before applying.
NCT06296147 · University of Pittsburgh Not Applicable · 1 country
Who might be able to join this trial: - You are 18 years old or older - You are male - You are scheduled to have a transperineal prostate biopsy (a procedure to take a small tissue sample from the prostate through the area between the scrotum and rectum) - You have signed and dated a consent form agreeing to take part...
NCT06303622 · Chinese University of Hong Kong Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older - People whose doctor suspects they may have prostate cancer and has recommended a prostate biopsy - People whose prostate-specific antigen (PSA) blood test result is below 20 ng/mL (a measure used to help detect prostate issues) - People whose rectal examina...
NCT06305390 · IRCCS San Raffaele Phase 2 · 1 country
Who might be able to join this trial: - Men aged 18 or older who have been referred by a doctor due to a suspicion of prostate cancer and are being considered for a prostate biopsy - People who are able to complete all of the procedures required by the trial - People who are able to give written consent to participate...
NCT06305832 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medic... Phase 2 · 1 country
Who might be able to join this trial: - You are male and at least 40 years old. - After surgery, your prostate tissue was confirmed to be a type of prostate cancer called adenocarcinoma. - After surgery, your lymph node results showed either no cancer in the lymph nodes, or lymph nodes were not tested. - Your PSA level...
NCT06315595 · Mayo Clinic Not Applicable · 1 country
Who might be able to join this trial: - Adults (18 years of age or older) Who may not be able to join: - People who have a cardiac pacemaker, as this is not compatible with MRI scanning - People who experience claustrophobia (fear of enclosed spaces), which may make MRI scanning difficult - People who have an implante...
NCT06318559 · Fondazione del Piemonte per l'Oncologia Not Applicable · 1 country
Who might be able to join this trial: - People who have signed a written consent form agreeing to take part and to the use of their personal data - People who are male and over 40 years of age - People who have had an MRI scan of the prostate done following specific guidelines, with results reported using a standard sc...
NCT06320067 · University College, London Phase 3 · 1 country
**Who might be able to join this trial:** **General eligibility (all participants):** - People who are at least 18 years old - People who have been confirmed by tissue testing to have prostate adenocarcinoma, or who are strongly suspected to have prostate cancer with a plan to confirm this before joining a treatment c...
NCT06320223 · University Hospital, Essen Not Applicable · 1 country
Who might be able to join this trial: - People who are adults diagnosed with prostate cancer that has been confirmed through a biopsy or tissue sample - People who have had a PSMA PET scan (any type) done to check the stage of their cancer or to re-check it at any point - People for whom at least 3 years of survival fo...
NCT06325774 · Changhai Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People whose general health and ability to carry out daily activities meets a certain minimum level, based on a standard medical scoring system called the ECOG scale (score of 2 or lower, meaning able to carry out basic self-care) - People who have b...
NCT06330805 · Ohio State University Comprehensive Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue sample taken within the past 270 days. - People whose prostate cancer is classified as "unfavorable intermediate risk," meaning it meets all of the followin...
NCT06330909 · University Hospital Freiburg Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer confirmed by a tissue biopsy (if the biopsy was done more than 12 months ago, a new one may be needed) - Your prostate cancer is localised (has not spread to lymph nodes or other parts of the body), and is classed as high-risk, ve...
NCT06331013 · European Institute of Oncology Not Applicable · 1 country
**Who might be able to join this trial:** - You are between 18 and 80 years old - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by a tissue sample) - Your prostate cancer falls into the low, intermediate, or high-risk category based on standard medical guidelines - Your...
NCT06334120 · Bayer Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 19 years or older - People with high-risk non-metastatic castration-resistant prostate cancer (a stage of prostate cancer that has not yet spread but is no longer responding to hormone-lowering treatment), where testosterone levels in the blood are very low and the...
NCT06335693 · Changhai Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People whose general health and ability to carry out daily activities falls within an acceptable range, as rated on a standard medical scale called the ECOG scale (scores 0–2, meaning fully active to capable of basic self-care) - People who have been diagnosed with prostate...
NCT06335914 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - People who have been confirmed through tissue or cell testing to have prostate cancer (specifically a type called adenocarcinoma) - People who are considered "poor risk" and have prostate cancer that has spread to other parts of the body (metastatic),...
NCT06343038 · University Hospital, Basel, Switzerland Phase 1 · 1 country
**Who might be able to join this trial:** - The patient has signed a consent form to take part in the trial - The patient is male and over 18 years of age - The patient has prostate cancer that has spread and no longer responds to hormone treatment (mCRPC), tests positive for PSMA, and has already received both a horm...
NCT06347705 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to sign a written consent form agreeing to take part and allowing their health information to be used for research purposes. - Men aged 18 years or older. - Men whose blood testosterone level is at or above 150 ng/dL, unless they are already o...
NCT06350825 · The First Affiliated Hospital with Nanjing Medical University Phase 3 · 1 country
Who might be able to join this trial: - Men aged 18 to 75 years old - People whose prostate cancer has been confirmed by a tissue biopsy to be a specific type called adenocarcinoma - People whose cancer has spread (metastasised) to other parts of the body, confirmed by imaging scans or biopsy - People whose cancer has...
NCT06353321 · University of Texas Southwestern Medical Center Not Applicable · 1 country
**Who might be able to join this trial:** - Men who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) and are already scheduled to have a standard PSMA-PET scan as part of their routine care, either to check the cancer at the time of first diagnosis or to look for signs that the cance...
NCT06355050 · Jena University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have not received hormone therapy (androgen deprivation therapy) in the 2 months before starting radiation treatment - People who are in good general health and able to carry out daily activities with little to no limitation (known as ECOG performance status 0 or 1) -...
NCT06355336 · Cincinnati Cancer Advisors Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer that has been confirmed by a tissue sample (biopsy or pathology test) - Your prostate cancer diagnosis was made on or after January 1st, 2023 - You are willing and able to sign a consent form to take part in the study - You are 18 year...
NCT06357416 · Royal Marsden NHS Foundation Trust Not Applicable · 1 country
Who might be able to join this trial: **Main Study** - People who are attending the Man Van mobile outreach clinic run by The Royal Marsden Hospital - People who are male and aged 45 or older **MV-POCT (Point-of-Care Testing sub-study)** - People who are having a PSA (prostate-specific antigen) and/or blood sugar (Hb...
NCT06362577 · RenJi Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men over the age of 40 - Men who have prostate cancer that has not spread beyond the prostate, and who are having a specific type of biopsy performed (either a transperineal template biopsy or an MRI-guided biopsy combined with a systematic biopsy) - Men whose cancer is at a...
NCT06363266 · St. Mary's Research Center, Canada Not Applicable · 1 country
Who might be able to join this trial: **For the person with prostate cancer:** - People who have been diagnosed with prostate cancer - People who have started or are about to start prostate cancer treatment (not including active surveillance), either coming up or received within the last 2 years - People who are able...
NCT06363435 · Elin Tragardh Not Applicable · 1 country
Who might be able to join this trial: - People who have been referred by their doctor for a specific type of PET-CT scan (called an 18F-PSMA-1007 PET-CT scan) at Skåne University Hospital in either Lund or Malmö, Sweden, as part of their normal medical care Who may not be able to join: - People who are under 20 years...
NCT06369246 · M.D. Anderson Cancer Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue or cell sample taken within the past year, with final confirmation done at MD Anderson Cancer Center. - People whose cancer is at a locally contained stage...
NCT06369610 · Mayo Clinic Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with high-risk prostate cancer (a specific type called adenocarcinoma), confirmed by a tissue sample test - People whose cancer has been staged at certain levels (T1c through T4, with lymph nodes ranging from not affected to affected, and either no...
NCT06378346 · University of Illinois at Chicago Phase 2 · 1 country
Who might be able to join this trial: - People who are 18 years of age or older at the time of signing consent - People whose general health and ability to carry out daily activities falls within an acceptable range as rated by a standard medical scale (ECOG score of 0, 1, or 2) - People who have been diagnosed with pr...
NCT06380738 · AstraZeneca Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to sign a written consent form agreeing to take part - People who are 18 years of age or older - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a tissue or cell sample test - People who...
NCT06384222 · Ivan de Kouchkovsky, MD Phase 2 · 1 country
Who might be able to join this trial: - People who are 18 years of age or older. - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer confirmed by a biopsy taken within the past 12 months) and have that tissue sample available if needed for future testing. - People whose can...
NCT06387056 · The First Affiliated Hospital of Xiamen University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 or older. - People who are willing to sign a consent form before joining the trial, as required by local regulations. - People whose imaging scans (including MRI, bone scan, and a special PET/CT scan called PSMA PET/CT) have confirmed locally...
NCT06391034 · Robert Bok, MD, PhD Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a biopsy. - People who have already had radiation therapy to the prostate, or who are currently thinking about or scheduled for external beam radiation therapy (EBRT). - Peop...
NCT06392295 · University of Miami Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue sample - Men aged 18 or older - People whose cancer has returned in a limited way, with no more than 5 spots of disease showing up on a PSMA PET/CT scan, all loc...
NCT06392737 · Peking University First Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 45 and 85 years old. - People who have had a complete prostate MRI scan (a detailed imaging test called mpMRI) with acceptable image quality, showing a suspicious area scored 3 or higher on a standard rating system called PI-RADS V2.1. - People whose test...
NCT06397703 · NYU Langone Health Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer through a biopsy, classified as "unfavorable intermediate risk," which includes at least one of the following: a Gleason score of 4+3; more than 50% of biopsy samples showing Gleason 7 cancer; or two to three specific inter...
NCT06398639 · Adam S. Kibel, MD Not Applicable · 1 country
**Who might be able to join this trial:** - You are able to understand the study information and are willing to sign a consent form agreeing to take part. - You are expected to live for more than 10 years based on your current health. - You have never been diagnosed with prostate cancer. - You are between 40 and 69 yea...
NCT06401980 · Swiss Cancer Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to participate, as required by Swiss law and international clinical trial regulations - People who have a confirmed diagnosis of prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue or cell sample - Pe...
NCT06402357 · University of Florida Phase 2 · 1 country
**Who might be able to join this trial:** - You have chosen to have a focused ultrasound treatment (called HIFU) for prostate cancer that has come back after radiation therapy - You are male and 18 years of age or older - You are able to carry out some or all of your normal daily activities (your doctor can confirm th...
NCT06406803 · Maastricht University Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer at Stage I, II, or III - People who are scheduled to have surgery to remove the prostate (called a prostatectomy) - People whose body weight falls within a healthy-to-moderate range (BMI between 18.5 and 35 kg/m²) (confirm with...
NCT06408298 · Lionel.D.Lewis, MD Early Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a pathologist, with a Gleason score of 6 or higher (a measure of how the cancer cells look under a microscope). - People whose prostate cancer is considered removable by surgery, and who already have a planned surge...
NCT06409910 · University Health Network, Toronto Phase 2 · 1 country
Who might be able to join this trial: - You are 18 years old or older - You are able to understand and agree to take part in the study (give informed consent) - You have been diagnosed with prostate cancer (specifically a type called adenocarcinoma, confirmed by a tissue test) - You are generally well enough to carry o...
NCT06419348 · First Affiliated Hospital of Chongqing Medical University Early Phase 1 · 1 country
Who might be able to join this trial: - People who are at least 18 years old. - People with suspected, newly diagnosed, or previously diagnosed prostate cancer, where tests (such as MRI, CT scan, or tissue biopsy results) show a positive PSMA expression. - People who are willing and able to sign a consent form agreeing...
NCT06429813 · Paul Viscuse Not Applicable · 1 country
Who might be able to join this trial: - People who are willing to sign and date a consent form agreeing to take part in the study. - People who are willing to follow all study procedures and are available for the full duration of the trial. - Men aged 18 years or older. - People who have been diagnosed with metastatic...
NCT06437574 · Cedars-Sinai Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed and dated a consent form agreeing to take part in the study. - People who are willing to follow all study procedures and are available for the full duration of the trial. - People who have at least one risk factor for cardiovascular (heart and blood ve...
NCT06441994 · Osaka University Phase 1 · 1 country
**Who might be able to join this trial:** - People diagnosed with prostate cancer that has stopped responding to hormone therapy (castration-resistant prostate cancer) and is getting worse, shown either by rising PSA levels (at least 2 ng/mL, measured three times at least one week apart, with two readings more than 50...
NCT06446401 · Uppsala University Not Applicable · 1 country
"Who might be able to join this trial: - You must have started a triple or double hormone therapy treatment no more than 3 months before beginning the main hormone-blocking therapy (ADT). - You must have prostate cancer that has spread to other parts of the body (with a high number of areas affected) at the time of joi...
NCT06449664 · The Swedish School of Sport and Health Sciences Not Applicable · 1 country
Who might be able to join this trial: - You are willing and able to sign a consent form to take part in the study - You have been diagnosed with prostate cancer that is confined to or near the prostate (confirmed by a tissue biopsy or similar test) - You are planned to receive radiation therapy combined with hormone th...
NCT06449781 · Maria Sklodowska-Curie National Research Institute of Oncology Phase 2 · 1 country
Who might be able to join this trial: - People who have signed a written consent form agreeing to take part in the study - People who have been diagnosed with high or very high risk prostate cancer, confirmed by a laboratory examination of tissue - People who have completed radical local treatment for their prostate ca...
NCT06451445 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - People who are over 50 years of age - People who are expected to live for at least 10 more years - People who have been diagnosed with prostate cancer through a tissue sample (biopsy), where the cancer is contained within the prostate and is at a clinical stage of T2c or low...
NCT06457919 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older who are able to give written consent to participate - People who have been confirmed through a tissue sample (biopsy) to have prostate cancer (certain subtypes with neuroendocrine features are allowed, but pure small cell carcinoma is not) - People wh...
NCT06461793 · Samsung Medical Center Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample taken within 6 months of joining the study - People whose prostate cancer is classified as high risk or higher, based on the tumour having spread to near...
NCT06461819 · Samsung Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer, confirmed by a tissue biopsy within the last 6 months before joining the study - Your prostate cancer is considered low-risk or medium-risk (meaning the cancer has not spread far, the cancer cells look relatively normal under a mi...
NCT06465966 · University of Florida Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer - People whose treatment area is the prostate only, or the prostate and seminal vesicles (a nearby part of the reproductive system), with no cancer spread to nearby lymph nodes - People whose body weight is under 350 lbs (a...
NCT06468332 · Azienda Ospedaliero Universitaria Maggiore della Carita Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 80 years of age - People who have signed a consent form showing they understand the study's purpose and are willing to take part, including allowing their MRI scans and tissue samples to be used for genetic and other analyses, and agreeing to attend reg...
NCT06473259 · Santa Chiara Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) that has spread to other parts of the body, and who have not previously received treatment for the spread of cancer (except for hormone therapy started no more than 4–6 months before a...
NCT06474806 · Curasight Phase 2 · 3 countries
"Who might be able to join this trial: - People whose prostate cancer has been confirmed by a pathology test and diagnosed as prostate adenocarcinoma (a specific type of prostate cancer) - People whose cancer is graded as ISUP grade 1, 2, or 3 (a scale used to describe how the cancer cells look under a microscope) - Pe...
NCT06480110 · Rigshospitalet, Denmark Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma or poorly differentiated carcinoma) confirmed by laboratory testing of tissue — note that cancers made up entirely of small-cell or high-grade neuroendocrine cells are not eligible, though...
NCT06482489 · University of Lausanne Hospitals Not Applicable · 1 country
Who might be able to join this trial: **Group 1 – Healthy volunteers (for MRI development):** - Healthy male volunteers aged 18 or older with no history of prostate cancer - Willing to be contacted if something unexpected is found during the scan - Able to provide signed consent to participate **Group 2 – Men with me...
NCT06482645 · Peking University First Hospital Not Applicable · 1 country
Who might be able to join this trial: - People aged between 45 and 85 years old - People who have never had a prostate biopsy before - People who have a single suspicious area in the prostate, with complete MRI scan data of acceptable quality, and a prostate imaging score (PI-RADS V2.1) greater than 3, meaning the susp...
NCT06487507 · University of Miami Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 18 and 80 years old who are already scheduled to have their prostate surgically removed as part of their standard medical care. - People with a body mass index (a measure of body weight relative to height) between 18.5 and 40. - People who are able to read, write...
NCT06490328 · Dongkook Pharmaceutical Co., Ltd. Phase 3 · 1 country
**Who might be able to join this trial:** - Adult males aged 19 or older - People whose prostate cancer has been confirmed through a tissue or cell sample (biopsy or lab test) - People whose testosterone (a hormone) level in the blood is above 150 ng/dL - People who are reasonably active and able to care for themselves...
NCT06491056 · Singapore General Hospital Not Applicable · 1 country
Who might be able to join this trial: - People diagnosed with a specific type of prostate cancer called prostate adenocarcinoma - People whose cancer has a Gleason score (a measure of how aggressive the cancer looks under a microscope) of no more than 4+4 - People whose cancer volume (the size of the cancerous area) is...
NCT06496581 · UNICANCER Phase 3 · 1 country
**Who might be able to join this trial:** - People who have signed a written consent form before any trial procedures begin (a trusted representative — not the trial doctor or sponsor — may sign on their behalf if they are physically unable to do so) - People aged 18 or older - People whose doctor estimates they have...
NCT06497283 · Gangnam Severance Hospital Not Applicable · 1 country
Who might be able to join this trial: - You are scheduled to have surgery under general anesthesia - You are between 20 and 60 years old - You are considered generally healthy or have only mild health conditions (as assessed by your anesthesiologist) - Your ideal body weight is between 50 and 80 kg (roughly 110 to 176...
NCT06500169 · University of Southern California Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer for the first time (not a recurring or second diagnosis) - People who have been receiving hormone therapy (to reduce testosterone) and/or hormone-blocking medication for more than 6 months - Men aged between 55 and 85 years old...
NCT06506643 · Vector Vitale LLC Phase 2 · 1 country
**Who might be able to join this trial:** **For the solid tumour groups (Phase I and Phase II):** - Adults aged 18 or older - People who have signed a consent form before any study procedures begin - People who are willing to be available and follow study procedures for the full duration of the trial - People whose g...
NCT06508567 · University Health Network, Toronto Not Applicable · 1 country
Who might be able to join this trial: - People who have previously had radiation therapy to the prostate bed area, with or without treatment to the pelvic lymph node regions - People whose prostate cancer has come back in the prostate bed area, confirmed by biopsy, MRI scan, and/or a PSMA-PET scan - People who have had...
NCT06509919 · Shanghai Changzheng Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are male and between 18 and 80 years old - Your PSA blood test result is between 4 and 10 ng/ml (a measure of a protein linked to prostate health) - You are already scheduled to have a prostate biopsy, AND at least one of the following applies: a specific ratio of your PS...
NCT06517719 · Novartis Pharmaceuticals Not Applicable · 1 country
Who might be able to join this trial: - People who are adult males diagnosed with metastatic castration-resistant prostate cancer (a form of prostate cancer that has spread and no longer responds to hormone-lowering treatments), where their treating doctor has decided to start them on a specific radioactive drug therap...
NCT06517901 · Albany Medical College Not Applicable · 2 countries
Who might be able to join this trial: - Men who are having a prostate biopsy (through either the rectum or the perineum) as part of their regular medical care because prostate cancer is suspected - Men who are medically suitable to undergo a prostate biopsy procedure, either a standard cognitive type or a fusion type t...
NCT06521710 · Sir Mortimer B. Davis - Jewish General Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are having robotic surgery to remove the prostate for high-risk localised prostate cancer, where "high-risk" is defined by at least one of the following: a Gleason grade (cancer aggressiveness score) of 8 or higher, a PSA level of 20 or higher, or imaging showing the c...
NCT06526299 · University of Washington Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and sign a consent form agreeing to take part in the study. - People who are able to follow all the requirements of the study. - People who are 18 years of age or older. - People who are reasonably active and able to care for themselves, bas...
NCT06533644 · Syncromune, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older. - People who are able to give written consent and follow the study procedures. - People with advanced or metastatic prostate cancer (adenocarcinoma type, confirmed by tissue or cell testing), without small cell or neuroendocrine features. - People on an...
NCT06534918 · University of Miami Not Applicable · 1 country
**Who might be able to join this trial:** **For patients:** - Adults aged 18 or older, of any sex or gender - People who are able to give their own consent to participate - People who can read and understand English or Spanish - People who have been diagnosed with breast, prostate, or colorectal cancer, have finished...
NCT06535802 · Mayo Clinic Not Applicable · 1 country
Who might be able to join this trial: - Consumer advocates who are part of a group called the iCCaRE Consortium - Clinicians (healthcare professionals) who are part of a program called Translational Research & Clinical Intervention Services (TRaCIS) - Certain iCCaRE consumer advocates taking part in early testing phase...
NCT06536725 · Tianjin Medical University Second Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer that has spread to internal organs (such as the liver or lungs), either through clinical assessment or laboratory/pathology testing - People aged 18 years or older - People whose general physical health and ability to carry out...
NCT06541210 · Mayo Clinic Not Applicable · 1 country
Who might be able to join this trial: **For Study Parts 1 and 3 (Program Staff and Community Members):** - People who are in one of these specific roles: Community Principal Investigator, CoLLab Program Manager, CoLLab Site Manager, CoLLab Community Advisory Board (CAB) member, or Community Health Worker at a particip...
NCT06542757 · NYU Langone Health Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with intermediate-risk prostate cancer, based on national guidelines - Your PSA blood test result is between 10 and 20 ng/ml, OR your Gleason score (a measure of cancer aggressiveness) is 7, OR your cancer has spread within the prostate to more than h...
NCT06543420 · Peking University First Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer at a specific stage (known as clinical stage cT2 to cT3a, with no spread to lymph nodes or other parts of the body) before surgery - People whose condition meets the medical requirements for a type of robotic-assisted prostate r...
NCT06546267 · IRCCS San Raffaele Not Applicable · 1 country
Who might be able to join this trial: - Adults over 18 years old who have prostate cancer and are being treated with one of the following radiation therapy techniques: image-guided radiation therapy (IGRT), intensity-modulated radiation therapy (IMRT), or stereotactic body radiation therapy (SBRT) Who may not be able...
NCT06549465 · Convergent Therapeutics Phase 2 · 1 country
**Who might be able to join this trial:** - People with castrate-resistant prostate cancer (a form of prostate cancer that keeps growing despite very low testosterone levels) that is getting worse, shown by rising PSA blood test results, growing tumours on scans, new or worsening bone disease, or new lesions found on...
NCT06559059 · NYU Langone Health Not Applicable · 1 country
**Who might be able to join this trial:** **For patients:** - People who are Veterans - People who are 18 years of age or older - People who have been newly diagnosed with lung, prostate, breast, or colon cancer within the past 3 months of a telemedicine visit - People who have attended an oncology (cancer care) appoi...
NCT06563388 · Roswell Park Cancer Institute Phase 3 · 1 country
**Who might be able to join this trial:** - You are 1 year of age or older - You are willing to give your consent to participate in the study - You are well enough to carry out some daily activities (your doctor can confirm this based on your overall health score) - Your doctor expects you to live for more than 6 mont...
NCT06567314 · M.D. Anderson Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and are willing to sign a consent form before the study begins. - People aged 18 or older. - People with advanced skin cancer (cutaneous squamous cell carcinoma, or cSCC) that cannot be removed by surgery and/or has spread to other parts of...
NCT06568094 · Jiangsu HengRui Medicine Co., Ltd. Phase 2 · 1 country
Who might be able to join this trial: - People who are able to give informed consent and are willing and able to attend scheduled medical visits and follow the study requirements. - Men aged 18 years or older (up to 80 years old during the early dose-testing phase) at the time of signing the consent form. - People with...
NCT06568562 · University of Utah Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who have been diagnosed with a specific type of prostate cancer (prostatic adenocarcinoma, not the small cell type), confirmed through a tissue or cell sample - People whose cancer has spread to other parts of the body, as shown on imaging scans -...
NCT06574880 · Angela Y. Jia, MD PhD Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older. - People whose general health and ability to carry out daily activities meets a certain fitness level (confirm with trial site). - People who have been confirmed through a tissue sample (biopsy) to have prostate cancer of a specific t...
NCT06575257 · Xijing Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old. - People who have been diagnosed with prostate cancer through a tissue or cell sample test, and whose doctors have determined that surgery to remove the prostate (radical prostatectomy) is an appropriate treatment option. - People who are larg...
NCT06579417 · University of California, San Diego Not Applicable · 2 countries
Who might be able to join this trial: - People who are 18 years of age or older - People who have been referred for a specialised prostate MRI scan because their doctor suspects prostate cancer - People whose MRI scan will be carried out using a specific standardised scanning method called the ART-Pro acquisition proto...
NCT06582446 · German Oncology Center, Cyprus Phase 2 · 1 country
**Who might be able to join this trial:** - A person whose prostate cancer has been confirmed by a tissue biopsy showing a specific type called adenocarcinoma (a re-biopsy may be needed if the original biopsy is more than 12 months old) - The cancer is considered a primary (original site) prostate cancer, confirmed by...
NCT06582628 · Fundacion Oncosur Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older. - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a tissue sample, without certain rare features (neuroendocrine differentiation or small cell features). - People who are willing and able to...
NCT06584279 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medic... Not Applicable · 1 country
Who might be able to join this trial: - People whose PSA (a prostate-related protein measured in the blood) level is above 4 ng/ml. - People whose prostate MRI scan shows either a suspicious area rated 4 or higher on a standard scoring system, or a suspicious area rated 3 on that scoring system combined with a relative...
NCT06585007 · Universitaire Ziekenhuizen KU Leuven Phase 3 · 1 country
**Who might be able to join this trial:** - Written agreement to take part in the trial has been provided by the person or their legal representative before any screening begins. - The person has a specific type of prostate cancer called acinar adenocarcinoma (including cases where the cancer cells have changed in a p...
NCT06592924 · Canadian Cancer Trials Group Phase 3 · 4 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has spread to other parts of the body (metastatic disease), confirmed either by a tissue or cell sample, or by a very high PSA level (above 100 ng/ml) combined with imaging showing spread. - People whose metastatic dis...
NCT06600698 · Milton S. Hershey Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** **Phase I (early safety phase):** - People who are willing and able to give informed consent and agree to follow all study procedures and attend all required visits - Men aged 40 years or older - People with a history of prostate cancer diagnosis, including those who have been...
NCT06600802 · Centre Jean Perrin Not Applicable · 1 country
**Who might be able to join this trial:** - You are male and older than 18 years of age - You are able to carry out basic daily activities with minimal or no limitations (confirm with trial site regarding activity level assessment) - You have been diagnosed with prostate cancer that has spread to other parts of the bo...
NCT06609005 · Shenzhen Ionova Life Sciences Co., Ltd. Phase 2 · 2 countries
**Who might be able to join this trial:** - You have given written agreement to take part in the trial. - You are male and aged 18 or older. - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a tissue test. - Your prostate cancer has stopped responding to hormone-lowerin...
NCT06610825 · Washington D.C. Veterans Affairs Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (specifically a type called adenocarcinoma) confirmed by a lab test - Your prostate cancer has spread to other parts of your body and is no longer responding to hormone treatments (this is called metastatic castration-resistant pr...
NCT06612580 · First Affiliated Hospital of Fujian Medical University Early Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer, whether they have already received treatment or not - People who have signed a written consent form agreeing to take part in the study Who may not be able to join: - People who have a known allergy to PSMA (a protein found on...
NCT06615752 · Charles Drew University of Medicine and Science Phase 2 · 1 country
**Who might be able to join this trial:** - You are willing to sign a consent form and agree to follow all study procedures for the full duration of the trial - You are male and 18 years of age or older - You have been diagnosed with prostate cancer that has spread to other parts of the body (metastatic prostate cancer...
NCT06616155 · University of Michigan Rogel Cancer Center Phase 2 · 1 country
Who might be able to join this trial: - Adult males aged 18 or older who have prostate cancer that has spread to other parts of the body, is no longer responding to hormone-lowering treatment, and has previously been confirmed as a specific type called adenocarcinoma. - People who have had their testosterone lowered to...
NCT06616597 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - Males aged 18 years or older - People diagnosed with a specific type of prostate cancer called prostate adenocarcinoma - People whose PSA level (a prostate cancer marker measured in blood) is 2.0 ng/mL or higher at the screening visit - People whose PSA levels have risen — wi...
NCT06617481 · AdventHealth Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with a localised prostate cancer (a type called adenocarcinoma) and have already had their prostate removed as a curative treatment. - People whose PSA blood test result is between 0.1 and less than 0.5 ng/ml (a measure of a protein that can indicat...
NCT06625034 · Mayo Clinic Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) - People whose cancer falls within certain stages of spread, as classified by a standard medical staging system (confirm with trial site if unsure about stage)...
NCT06625970 · UNICANCER Phase 3 · 2 countries
**Who might be able to join this trial:** - People who have signed a written consent form before any trial procedures begin (a trusted representative, who is not the investigator or sponsor, may sign on behalf of someone who is physically unable to do so) - Men aged 18 to 80 years - People who are fully active or have...
NCT06626022 · University of Alberta Phase 3 · 5 countries
Who might be able to join this trial: - You are male - You are between 50 and 70 years old - You have a PSA blood test result between 3 and 20, and/or your doctor found something unusual during a rectal examination - You have never had a prostate biopsy before Who may not be able to join: - You have previously been di...
NCT06626386 · Heinrich-Heine University, Duesseldorf Not Applicable · 1 country
Who might be able to join this trial: - Men between the ages of 45 and 70 years old - People who have agreed to have their PSA (a blood marker related to prostate health) measured as part of prostate cancer screening Who may not be able to join: - People who are not able to give their own consent to participate Impor...
NCT06629779 · Pfizer Phase 3 · 27 countries
Who might be able to join this trial: - A diagnosis of prostate cancer (a specific type called adenocarcinoma, confirmed by a tissue or cell sample) that does not have small cell features. - Cancer that has spread to the bones (seen on a bone scan) or to other soft tissues in the body (seen on a CT or MRI scan). - Canc...
NCT06632977 · Alliance for Clinical Trials in Oncology Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue or cell sample, including less common types such as neuroendocrine, small cell, or sarcomatoid prostate cancer. - People who have measurable or detectable cancer that has spread to other parts of the body,...
NCT06633380 · University of Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - Women who have gone through menopause, were born female, and have been diagnosed with stage I, II, or III breast cancer, and have been taking aromatase inhibitor medication for at least 3 months before the study begins - People with a body mass index (BMI) of 25 or higher (a...
NCT06636123 · Virginia Commonwealth University Phase 1 · 1 country
**Who might be able to join this trial:** - People diagnosed with prostate cancer who have been treated with androgen deprivation therapy (a treatment that lowers male hormones) and at least one additional hormone-blocking medication (such as abiraterone, enzalutamide, apalutamide, or darolutamide). - People whose tes...
NCT06636526 · Institute of Cancer Research, United Kingdom Not Applicable · 1 country
Who might be able to join this trial: - People who were born male (and therefore have a prostate). - People aged between 40 and 55 years old. - People of Black African, Black African-Caribbean, White European, South Asian, or East Asian ancestry — defined as having all four grandparents from the same ancestry backgroun...
NCT06636682 · Cellvax Therapeutics Inc Phase 2 · 1 country
**Who might be able to join this trial:** - People diagnosed with localized high-risk or very high-risk prostate cancer, based on a standard cancer classification system (NCCN v4.2023). - People whose prostate biopsy results show cancer in 3 or more biopsy samples, with cancer covering at least half of each of those s...
NCT06636747 · The First Affiliated Hospital with Nanjing Medical University Not Applicable · 1 country
Who might be able to join this trial: - You have had a standard MRI scan of the prostate that included specific types of imaging (called T2WI, cDWI, hrDWI, and ADC maps) (confirm with trial site if unsure which scans you had) - Your medical records and health information are complete and available Who may not be able...
NCT06637267 · Kantonsspital Aarau Not Applicable · 1 country
Who might be able to join this trial: - Male patients between 45 and 80 years old who are already scheduled to have a prostate MRI scan followed by a prostate biopsy as part of their normal medical care - Patients who have signed a consent form agreeing to take part in the trial Who may not be able to join: - Patients...
NCT06638541 · Royal Marsden NHS Foundation Trust Not Applicable · 2 countries
**Who might be able to join this trial:** - Men aged 18 or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that requires treatment with radiation therapy - People whose cancer has been graded as Gleason score 3+3, 3+4, or 4+3 (also called Grade Groups 1, 2, or 3 — me...
NCT06640959 · The Christie NHS Foundation Trust Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who are able to give their consent to participate - People who have recently been diagnosed with prostate cancer that has been confirmed by a tissue sample (biopsy), is contained within or near the prostate (has not spread to lymph nodes or other parts o...
NCT06650579 · Emory University Phase 3 · 1 country
Who might be able to join this trial: - Men aged 18 or older - People with prostate cancer that has not spread to other parts of the body - People with prostate cancer that has not spread but where a specific blood marker (PSA) has risen again after previous treatment - People for whom a doctor has planned radiation th...
NCT06652607 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older - Men who have been diagnosed with prostate cancer (specifically adenocarcinoma) that has spread to other parts of the body, confirmed through a tissue or cell sample - People whose general health and ability to carry out daily activities meets a certa...
NCT06654336 · Ontario Clinical Oncology Group (OCOG) Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with localised prostate cancer (confirmed by biopsy) and were treated with radiotherapy at least 2 years before joining the study. - People whose prostate cancer has come back and spread to no more than 5 sites in the body, as seen on imaging scans...
NCT06655259 · Fudan University Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part and have signed a consent form agreeing to participate. - People aged between 18 and 80 years old. - People who have been confirmed through laboratory testing (from tissue or fluid samples) to have a specific type of prostate cancer called...
NCT06657131 · Heinrich-Heine University, Duesseldorf Not Applicable · 1 country
Who might be able to join this trial: - People who have given their informed consent to participate. - People who are already having a specific type of nuclear medicine scan called a \[18F\]PSMA-1007 PET scan as part of their regular medical care. Who may not be able to join: - People whose scan was affected by techni...
NCT06659614 · Abramson Cancer Center at Penn Medicine Not Applicable · 1 country
"Who might be able to join this trial: **Group 1 – Carriers:** - People who have been confirmed to carry a gene change (variant) known to be linked to a higher risk of prostate cancer - People who are having a prostate biopsy as part of prostate cancer screening, or who are having a biopsy or prostate removal surgery...
NCT06659926 · The Netherlands Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that has been confirmed by a tissue sample (biopsy). - Your cancer has been getting worse despite previous treatment, shown by rising PSA levels or new growth seen on scans. - A bone scan has shown cancer has spread to the bones, w...
NCT06661122 · Bayer Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed through a tissue or cell sample test. - People whose prostate cancer has spread to other parts of the body (metastatic), but only at a low level — meaning they do not have c...
NCT06666270 · Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd Phase 1 · 1 country
Who might be able to join this trial: - People who have signed the written consent form agreeing to take part in the trial - People aged 18 years or older, of any sex - People with a life expectancy of at least 12 weeks - People with a general health and activity level rated as 0 or 1 on a standard medical scale called...
NCT06672926 · University Hospitals of North Midlands NHS Trust Not Applicable · 1 country
Who might be able to join this trial: - MRI radiographers (medical imaging specialists) who work at University Hospitals of North Midlands (UHNM) or University Hospitals of Derby and Burton (UHDB) and have more than 5 years of experience performing MRI scans of the prostate. - Radiographers from UHNM or UHDB who have c...
NCT06674863 · Emory University Not Applicable · 1 country
Who might be able to join this trial: - People who identify as Black or African American men, as recorded in medical records and by self-report, who have finished their main surgery and/or radiation treatment for prostate cancer that was localised or had spread to only a small number of areas, and who completed that tr...
NCT06675357 · University of Wisconsin, Madison Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You are able and willing to give your formal agreement to take part in the study - You have been diagnosed with prostate cancer - You are scheduled for, or have recently had (within the last 4 weeks), a standard PSMA PET scan as part of your...
NCT06678828 · Nanostics Not Applicable · 1 country
Who might be able to join this trial: - People who are male and 18 years of age or older - People who have been referred to a urology specialist due to a suspected prostate cancer - People who have never previously been diagnosed with prostate cancer - People who are willing to take part in the study - People who are a...
NCT06683066 · The Affiliated Hospital of Qingdao University Phase 1 · 1 country
Who might be able to join this trial: - People who are willing to take part voluntarily and sign a consent form showing they understand the trial, its process, and possible side effects - Men aged 18 or older who weigh at least 50 kg and have a body mass index (BMI) between 19 and 30 - Men diagnosed with prostate cance...
NCT06687421 · Andreas Josefsson Not Applicable · 1 country
Who might be able to join this trial: - Men who are being checked by doctors for possible prostate cancer - People who have signed a consent form agreeing to take part Who may not be able to join: - People who have difficulty understanding information about the study, for example due to language barriers, cognitive ch...
NCT06691776 · The Netherlands Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** **General requirements (all groups):** - Adults aged 18 or older who have been referred for a radiotherapy treatment plan that matches one of the specific cancer groups in the trial - People with a general health and activity level that falls within a certain range (rated 0–3...
NCT06700057 · Institut Bergonié Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People with prostate cancer that has spread to other parts of the body, is no longer responding to hormone-lowering treatments, and has high levels of a protein called PSMA on the cancer cells. - People whose prostate cancer has been treated with taxane...
NCT06702995 · Evopoint Biosciences Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and sign the official consent form for the study - People aged 18 or older at the time of signing the consent form - People with a life expectancy of at least 3 months - People with a good general level of physical functioning, as measured b...
NCT06705686 · TechnoGenesys, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has spread to other parts of the body and is no longer responding to hormone-lowering treatments (confirmed by a tissue or cell sample). - People who have visible signs of cancer spread on standard scans such as CT, MR...
NCT06709326 · Umeå University Not Applicable · 1 country
**Who might be able to join this trial:** **General requirements for all groups (Arms 1, 2, and 3):** - People whose veins are suitable for an apheresis procedure (a process where blood is drawn out, filtered, and returned to the body) - People with a general health and activity level rated as ECOG 0–2 (meaning they a...
NCT06714630 · University of Edinburgh Not Applicable · 1 country
Who might be able to join this trial: - You must have received external beam radiotherapy (a type of radiation treatment) delivered using a machine called a linear accelerator - Your PSA (a prostate-related protein measured by a blood test) must have been regularly recorded after your radiotherapy treatment - You must...
NCT06717295 · Javier Toledo Not Applicable · 3 countries
**Who might be able to join this trial:** **Phase 1 (CCANED):** - Adults aged 40 years or older. - People who have a confirmed diagnosis of one of these cancer types: Non-Small Cell Lung Cancer, Glioblastoma Multiforme (a type of brain tumour), Colorectal Cancer, Liver Cancer (Hepatocellular Carcinoma), Breast Cancer,...
NCT06717711 · Regina Elena Cancer Institute Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 to 75 years old - People whose PSA blood test result is below 10 ng/mL before surgery - People whose prostate cancer has been graded as ISUP grade 2 or lower, and has not spread beyond the prostate (stage cT2 or lower), based on a biopsy - People who are havin...
NCT06719206 · Mälardalen University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with breast, prostate, or colorectal cancer and are planned to start, or have recently started, treatment such as chemotherapy, radiotherapy, or hormone therapy at hospitals in Uppsala or Västerås, Sweden. Who may not be able to join: - People who...
NCT06730243 · Ministry of Science and Technology of the People´s Republic of China Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer for the first time, confirmed by a tissue test (biopsy) - People for whom doctors have recommended surgery to remove the prostate as the main treatment with the aim of curing the cancer - People aged 80 years or younger - Pe...
NCT06733350 · Roswell Park Cancer Institute Phase 4 · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - Men who have been diagnosed with localized prostate cancer that falls into the very low, low, or favorable intermediate risk categories according to NCCN guidelines, and whose cancer is being managed with active surveillance (monitoring rather tha...
NCT06737588 · Anhui Provincial Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been advised to consider a prostate biopsy based on standard medical guidelines - You have had a recent PSA blood test showing a result below 100 ng/ml (a measure of a protein linked to prostate health) - Your prostate concern appears to be a new, primary issue with...
NCT06738303 · Case Comprehensive Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer that has spread to other parts of the body, is no longer responding to hormone therapy (castrate-resistant), and has previously been treated with a specific type of hormone-blocking medication called an androgen receptor pa...
NCT06740071 · The University of Hong Kong Not Applicable · 2 countries
"Who might be able to join this trial: - People aged between 18 and 85 years who have been diagnosed with prostate cancer and have already had their prostate removed through a keyhole (laparoscopic) surgical procedure Who may not be able to join: - People who are currently taking part in another clinical trial - Peopl...
NCT06748456 · University of Copenhagen Not Applicable · 1 country
Who might be able to join this trial: - Your group (called a "quality cluster") has a coordinator who oversees it - Your quality cluster is willing to hold a group meeting in 2025 focused on the topic of PSA (confirm with trial site) Who may not be able to join: - Your quality cluster has already scheduled and planned...
NCT06754085 · HTA Co., Ltd. Phase 3 · 1 country
**Who might be able to join this trial:** - People who have fully understood the study details and risks, and have agreed to take part by signing a consent form - Men aged 18 or older - People who have been confirmed through tissue testing to have a type of prostate cancer called prostate adenocarcinoma, and who have...
NCT06754488 · Suzhou Municipal Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer confirmed by a needle biopsy before surgery - Your cancer is at an early stage (classified as stage T1 or T2, meaning it is still contained within or very close to the prostate) **Who may not be able to join:** - You have a seriou...
NCT06756334 · Anhui Provincial Hospital Early Phase 1 · 1 country
**Who might be able to join this trial:** - Be between 18 and 90 years old - Have complete MRI scans and medical records available (such as PSA blood test results and cancer grading information) - Have prostate cancer found through a PSA blood test or imaging scan, or be suspected of having the cancer come back after s...
NCT06758882 · Marco Oderda Phase 2 · 1 country
**Who might be able to join this trial:** - You are between 18 and 79 years old - You have signed a consent form showing you understand and agree to take part in the study - Your prostate cancer has been confirmed by a tissue biopsy as a type called adenocarcinoma - Your cancer is considered high-risk, with a Gleason...
NCT06759701 · M.D. Anderson Cancer Center Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer through a tissue biopsy, where the cancer is contained within the prostate (no spread to other areas), and the cancer falls into an intermediate-risk category based on specific test results (confirm with trial site for full...
NCT06762379 · European Institute of Oncology Not Applicable · 1 country
Who might be able to join this trial: - You have prostate cancer that has spread to other parts of the body (metastatic), and there is not enough tumor tissue available to do genetic/molecular testing. - You are willing and able to sign a written consent form before joining the trial. Who may not be able to join: - Yo...
NCT06773598 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older at the time of the examination - People who have given their written agreement (informed consent) to take part - People who have one or more areas of concern found on a prostate MRI scan, rated on a standard scoring system (PI-RADSv2.1) wit...
NCT06773806 · Institut National de la Santé Et de la Recherche Médicale, France Not Applicable · 1 country
**Who might be able to join this trial:** *For people newly diagnosed with prostate cancer (main study group):* - Men newly diagnosed with prostate cancer in Martinique, identified through multi-specialist medical meetings, across all public and private healthcare services over a three-year period - Men aged under 75...
NCT06774781 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - People who have one or more areas of concern in the prostate identified on a specific type of MRI scan, rated at a level of 3 or higher on a standard prostate imaging scoring system (called PI-RADS v2.1), assessed at a particular hospital in Bologna, Italy - People for whom their...
NCT06776172 · University Hospital, Basel, Switzerland Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 or older with a life expectancy of more than 15 years - People with prostate cancer confirmed by biopsy, classified as WHO/ISUP grade group III, IV, or V - People with high-risk prostate cancer, which includes either a biopsy-confirmed WHO/ISUP grade group III–...
NCT06783127 · Santa Chiara Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have prostate cancer that has spread to other parts of the body, is no longer responding to hormone therapy, carries a BRCA gene mutation, and are being treated with olaparib as part of their regular medical care (not as part of a clinical trial) Who may not be able t...
NCT06783829 · Jiangsu HengRui Medicine Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are male and between 18 and 85 years old - People whose general physical health is rated as good to fully active (a score of 0 or 1 on a standard medical scale used to measure daily functioning) - People who are expected to live for at least 6 months - People who h...
NCT06784986 · Brazilian Institute of Robotic Surgery Phase 4 · 1 country
Who might be able to join this trial: - People who have prostate cancer and are scheduled to have their prostate removed using robotic surgery Who may not be able to join: - People who are older than 65 or younger than 18 years of age - People who have a known allergy to anti-inflammatory pain medicines (NSAIDs), morp...
NCT06785636 · Pathos AI, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma, confirmed by tissue testing) - People whose cancer has spread to other parts of the body (metastatic disease), confirmed by imaging taken...
NCT06788886 · Mayo Clinic Not Applicable · 1 country
**Who might be able to join this trial:** **Study 1:** - You must be physically healthy enough to do light exercise. - You must be able to read and understand English well enough to give consent, follow instructions, and complete any forms or questionnaires. - You must have access to a smartphone or tablet. **Study 2...
NCT06798558 · Hackensack Meridian Health Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed through a tissue sample. - People whose cancer is considered high-risk, based on a biopsy score of Gleason Score 8 or higher (also called Grade G...
NCT06800313 · Janssen Research & Development, LLC Phase 2 · 2 countries
Who might be able to join this trial: **For all parts of the trial:** - Men aged 18 or older - People whose prostate cancer has been confirmed by laboratory testing of tissue or cell samples - People whose blood counts, kidney function, and liver function are at adequate levels - People who are able to swallow tablets...
NCT06801236 · Acerand Therapeutics (Hong Kong) Limited Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent to participate - People who have prostate cancer that has spread to other parts of the body (metastatic) and is no longer responding to hormone-reducing treatments, and who are either on ongoing hormone-suppression thera...
NCT06804785 · Northwestern University Not Applicable · 1 country
Who might be able to join this trial: - People who have a PSA level between 4.0 and 10.0 ng/ml, or an abnormal prostate exam with a PSA level between 2.0 and 10.0 ng/ml, as shown in their lab results. - People who have never had a prostate biopsy before, confirmed by their own report or medical records. - Men aged 18 t...
NCT06807359 · SpectraCure AB Phase 2 · 2 countries
Who might be able to join this trial: - Adults aged 18 years or older. - People with prostate cancer (specifically a type called adenocarcinoma) that has been confirmed by a tissue sample (biopsy) taken within the last 9 months, where the cancer is contained within the prostate gland. - People who are on active surveil...
NCT06815354 · AIQ Solutions Not Applicable · 1 country
Who might be able to join this trial: - People aged 18 or older who are willing and able to give their informed consent to participate. - People who have been diagnosed with prostate cancer that has spread to other parts of the body (metastatic prostate cancer). - People whose doctor has planned for them to start a tre...
NCT06818682 · Tata Memorial Centre Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy, and whose doctors consider them suitable for radiotherapy aimed at curing the cancer - People whose cancer has been assessed using specialist scans (PSMA-PET/CT and MRI) and found to be at a ce...
NCT06820333 · Heinrich-Heine University, Duesseldorf Not Applicable · 1 country
Who might be able to join this trial: - You are older than 18 years of age - You have been recently diagnosed with prostate cancer for the first time and have a planned PET/CT scan using a special imaging agent called PSMA-1007 - You are willing and able to give your consent to take part in the trial Who may not be ab...
NCT06822036 · St. Antonius Hospital Gronau Not Applicable · 1 country
Who might be able to join this trial: - People aged 45 years or older, up to 68 years of age - People who have been diagnosed with prostate cancer confirmed by biopsy and have been treated with a robotic-assisted surgical removal of the prostate - People whose surgery involved a technique that aimed to preserve the ner...
NCT06822452 · Elsan Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older who have prostate cancer for which a specialist medical team has recommended surgical removal of the prostate (with or without removal of nearby lymph nodes) as a treatment option - People who are willing and able to follow all medical instructions given duri...
NCT06824818 · University of Chicago Not Applicable · 1 country
Who might be able to join this trial: - People who have prostate cancer and have been on a type of hormone therapy called LHRH agonist therapy for more than 3 years - People who are aged 70 years or older - People whose general health and ability to carry out daily activities meets a certain level, known as an ECOG per...
NCT06825091 · University Health Network, Toronto Phase 3 · 1 country
Who might be able to join this trial: - People who are over 18 years old - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer confirmed by a tissue sample) - People whose prostate cancer has not spread beyond the prostate (localized cancer) - People whose cancer falls into t...
NCT06825715 · VA Office of Research and Development Not Applicable · 1 country
Who might be able to join this trial: - People who are VA (Veterans Affairs) patients with lung or prostate cancer and are receiving care at an oncology clinic Who may not be able to join: - People whose cancer started somewhere other than the prostate or lung (for example, a cancer that spread to the lung or prostate...
NCT06826924 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) - People with a general health and activity level rated as fully active or restricted only in physically strenuous activity (ECOG score of 0 or 1) - People whose...
NCT06828263 · University Hospital, Grenoble Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with prostate cancer of a specific type called adenocarcinoma - People whose prostate cancer has spread to other parts of the body, is no longer responding to treatments that lower testosterone (castration-resistant), and is getting...
NCT06834152 · University of Zurich Not Applicable · 2 countries
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that is confirmed by a tissue sample (biopsy) and has not spread beyond the prostate area - Your planned treatment is a specific type of focused radiation therapy (called SBRT) delivered in 5 weekly sessions, following an establis...
NCT06834321 · baotai Liang Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 85 years old - People whose prostate cancer has been confirmed by a tissue sample (biopsy), and does not have a specific subtype called "small cell" features - People whose prostate cancer has spread to other parts of the body (bone or lymph nodes), with 5...
NCT06835725 · British Columbia Cancer Agency Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People who are able to give informed consent to participate. - People who are generally well enough to carry out daily activities with little or no limitation (this is measured using a standard medical scale called ECOG, scores 0–2). - People who a...
NCT06841211 · Peking University First Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People aged between 18 and 85 years old - People who have never had a prostate biopsy before - People who have more than one suspicious area visible on their prostate MRI scan - People where every suspicious area on the MRI meets specific guidelines for biopsy (rated PI-RADS...
NCT06842498 · Kyntra Bio Phase 2 · 1 country
**Who might be able to join this trial:** - People who have had their prostate cancer confirmed as adenocarcinoma (a specific type of prostate cancer) through a tissue or cell sample from all previous biopsies. - People with tumours in soft tissue who have an accessible lesion must agree to a biopsy during the screeni...
NCT06844383 · Prostate Cancer Clinical Trials Consortium Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give written consent before any screening takes place (or have a legal representative do so on their behalf). - People who are 18 years of age or older. - People who are willing to be assigned to either treatment group and follow the study...
NCT06849544 · Clinton Bahler Phase 2 · 1 country
Who might be able to join this trial: - People who have signed and dated a consent form and a HIPAA privacy form - Men aged 18 years or older - People with a confirmed diagnosis of prostate cancer that is Grade Group 3 to 5 (a higher-risk grade) or has spread beyond the prostate, OR has spread into the outer layer of t...
NCT06854250 · Sun Yat-sen University Phase 2 · 1 country
Who might be able to join this trial: - Men between 18 and 80 years old - People whose prostate cancer has been confirmed by a tissue sample (biopsy) as a specific type called acinar adenocarcinoma - People whose prostate cancer had already spread to other parts of the body at the time it was first diagnosed, based on...
NCT06856694 · Cedars-Sinai Medical Center Not Applicable · 1 country
Who might be able to join this trial: - Patients who are attending their first treatment consultation for prostate cancer that has not spread beyond the prostate - Patients who were previously on active surveillance (monitoring without treatment) for prostate cancer but whose cancer has been upgraded and are now consid...
NCT06859203 · Technical University of Munich Not Applicable · 1 country
Who might be able to join this trial: - The person must be male and older than 18 years of age. - The person must have a history of localised prostate cancer (a specific type called adenocarcinoma) that was previously treated with the aim of curing it, and the cancer must now be showing signs of returning based on a bl...
NCT06861192 · baotai Liang Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 to 85 years old - People whose prostate cancer has been confirmed by a tissue sample (biopsy), and whose cancer does not have a specific aggressive cell type called "small cell" features - People whose prostate cancer has spread to other parts of the body (such...
NCT06862856 · Massachusetts General Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (specifically adenocarcinoma) confirmed by biopsy, and who have already had their prostate surgically removed (radical prostatectomy) as a curative treatment. - People who have a detectable but very low PSA level after surg...
NCT06863090 · East and North Hertfordshire NHS Trust Not Applicable · 1 country
**Who might be able to join this trial:** - Adults aged 18 years or older - People receiving a specific type of internal radiation treatment called HDR brachytherapy (using a radioactive source called iridium-192), either on its own or combined with external radiation, for prostate cancer that has been confirmed by bi...
NCT06864533 · Peking University First Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a biopsy or surgery, with a high-grade cancer score (Gleason score of 9–10, or containing the most aggressive grade components) - People whose scans show no signs that the cancer has spread to distant parts of t...
NCT06865768 · Emory University Phase 2 · 1 country
**Who might be able to join this trial:** - You are male and over 18 years old - You have a suspected prostate cancer diagnosis and are already scheduled to have a prostate biopsy to confirm this - You are able to lie still during an MRI scan - You are willing and able to sign a written consent form to participate **W...
NCT06866782 · Fundacio Puigvert Not Applicable · 8 countries
Who might be able to join this trial: - Adults who are male and aged 18 or older, with no upper age limit - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy) - People who need imaging scans to check for signs of cancer spread, either at the time of first diagnosis or after c...
NCT06867588 · Jules Bordet Institute Not Applicable · 1 country
Who might be able to join this trial: - Men aged 18 or older - People who have had a specific type of prostate scan (called a multiparametric MRI) within the last 6 months - People whose MRI scan showed at least one area of concern rated as "PI-RADS 3" (a mid-level finding that is considered unclear or uncertain) - Peo...
NCT06875258 · The Netherlands Cancer Institute Phase 4 · 1 country
**Who might be able to join this trial:** - People aged between 18 and 70 years old - People who have a naturally developed penis, with no prior surgical changes to it - People who have been diagnosed with prostate cancer confirmed by a laboratory tissue test - People who are scheduled to have their prostate surgicall...
NCT06877598 · University Health Network, Toronto Not Applicable · 1 country
**Who might be able to join this trial:** - People with localised prostate cancer who are scheduled to have their prostate removed (by open or robotic surgery) or to receive radiation treatment (such as brachytherapy or external beam radiation), either alone or combined with hormone therapy - People who are currently...
NCT06893783 · Inkeun Park Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given written consent to participate before any study-related activities begin. - People aged 19 years or older at the time of signing the consent form. - People who have been diagnosed (confirmed by tissue testing) with a type of cancer called extra-pulmonar...
NCT06904313 · Akiva Mintz Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 years or older. - People who are able to give informed consent and follow the study procedures. - Women of childbearing potential must not be pregnant or breastfeeding, and a negative pregnancy test is required. Who may not be able to join: - People whose total ra...
NCT06904625 · Institut Claudius Regaud Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with breast cancer (of any type, including triple-negative, hormone receptor-positive/HER2-negative, or HER2-positive) or prostate cancer that has spread to multiple sites in the body, and where a new round of treatment is being considered. - People...
NCT06907446 · University of California, Davis Not Applicable · 1 country
Who might be able to join this trial: - Adults over the age of 18 who are scheduled to have a prostate biopsy procedure Who may not be able to join: - People who are unable to give their own consent to take part in the trial - People with other health conditions that, in the opinion of the trial doctor, could interfer...
NCT06908694 · Hamilton Health Sciences Corporation Phase 4 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer by a doctor - People who are currently receiving, or are planned to receive, a hormone therapy called androgen deprivation therapy (ADT), which may be used alone or combined with other prostate cancer medications - People with a...
NCT06914544 · University Hospital Schleswig-Holstein Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer that has not spread beyond the prostate (confirmed by a tissue biopsy) - Your cancer is at an early, localised stage (stages cT1 to T2c, with no spread to lymph nodes or other parts of the body) - Your cancer grade is considered lo...
NCT06915909 · East and North Hertfordshire NHS Trust Not Applicable · 1 country
**Who might be able to join this trial:** - People who are scheduled for a non-emergency robotic prostate removal surgery - People (or their legal representatives) who are able to give written consent to take part in the study - Males between 18 and 75 years of age - People who do not have significant mental health con...
NCT06922318 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by a tissue sample) - You are physically able to carry out basic daily activities, with only mild limitations at most (confirm with trial site) -...
NCT06923657 · First Affiliated Hospital of Fujian Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People whose blood test shows a PSA (prostate-specific antigen) level above 4 ng/mL - People who have had at least one prostate biopsy in the past that came back negative (no cancer found) - People whose PSA levels, and/or PHI (a related prostate health marker) levels, have...
NCT06926283 · Hangzhou DAC Biotechnology Co., Ltd. Phase 1 · 1 country
**Who might be able to join this trial:** - People who are willing to sign a consent form and follow the study requirements - Adults aged 18 to 75 years (male or female) - People with a life expectancy of at least 6 months - People who are well enough to carry out daily activities with little to no limitation (based o...
NCT06927635 · University Health Network, Toronto Phase 2 · 1 country
Who might be able to join this trial: - Adults older than 18 years of age - People who are able to give their informed consent to participate - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by tissue testing) - People whose prostate cancer has continued to grow or...
NCT06931340 · Alliance for Clinical Trials in Oncology Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed by laboratory testing of tissue or cell samples, not including a rare type called small cell prostate cancer - People who have evidence of prostate cancer that has spread (metas...
NCT06941363 · University of Milano Bicocca Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - People who have given their written, voluntary consent to participate before the study begins - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) and have had their prostate surgically removed (any surgic...
NCT06945315 · Icahn School of Medicine at Mount Sinai Phase 3 · 1 country
Who might be able to join this trial: - People who are over 18 years old at the time of signing the consent form - Men who are currently sexually active and have normal erectile function (based on a standard questionnaire score), and who are planned to have a type of prostate surgery (robotic-assisted) that aims to pre...
NCT06946771 · Zhen Li Not Applicable · 1 country
Who might be able to join this trial: - Adult males who have an elevated PSA (a prostate blood test result above 4.0 ng/ml), an abnormal prostate check done by a doctor's physical examination, or a suspicious finding on a prostate ultrasound, CT scan, or MRI - People who are willing to take part in the trial and have s...
NCT06949254 · Istituto Clinico Humanitas Not Applicable · 1 country
**Who might be able to join this trial:** - People who are older than 18 years of age - People whose general health and ability to carry out daily activities meets a certain minimum level (confirm with trial site) - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy - People whose prostate...
NCT06960291 · University of Calgary Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with cancer, or who have had a cancer diagnosis in the past - People who are 18 years of age or older - People who are able to take part in at least low-intensity physical activity (such as gentle movement or light exercise) - People who are awa...
NCT06960798 · University of Oklahoma Not Applicable · 1 country
Who might be able to join this trial: - You must be willing and able to sign and date a consent form before any study procedures begin. - You must be at least 18 years old when you sign the consent form. - You must identify yourself as Native American. - You must have a confirmed diagnosis of prostate cancer (any stage...
NCT06970119 · Yunhe Pharmaceutical (Tianjin) Co., Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to take part, understand what the study involves, and are able to sign a consent form in person. - People who are at least 18 years old at the time of signing the consent form. - People who have been diagnosed with prostate cancer confirmed by a tissue...
NCT06971211 · Jianbin Bi Phase 2 · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 or older - People whose general health and ability to carry out daily activities meets a specific standard (called ECOG score 0 or 1 — confirm with trial site if unsure what this means) - People with metastatic castration-resistant prostate ca...
NCT06972511 · RenJi Hospital Phase 3 · 1 country
**Who might be able to join this trial:** - You must be younger than 75 years old. - Your quality of life score, measured using a standard questionnaire called the EORTC QLQ-C30, must be at a level of 2 (confirm with trial site). - You are expected to have a life expectancy of at least 10 years. - You have been diagnos...
NCT06972628 · Ebrahim S Delpassand Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and sign a consent form agreeing to take part in the study. - People who are willing and able to follow all study requirements. - People who are 18 years of age or older. - People whose bone scan shows a specific pattern called a "superscan,...
NCT06972875 · University of Vermont Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who are currently receiving Androgen Deprivation Therapy (ADT) for prostate cancer — this includes men who have had surgical removal of the testicles, or who are taking hormone-blocking injections or pills (such as leuprolide, degarelix, or relugolix). -...
NCT06981377 · Santa Chiara Hospital Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer - You are eligible to receive medication-based treatment for prostate cancer - You have agreed to take part in the study and given your consent Who may not be able to join: - Your cancer diagnosis (confirmed by tissue sample) is somet...
NCT06982469 · Clinica Universidad de Navarra, Universidad de Navarra Not Applicable · 1 country
Who might be able to join this trial: - People with prostate cancer who have had their prostate surgically removed and whose PSA levels are rising again, with imaging scans (PET and MRI) showing the cancer has come back only in the area where the prostate used to be. - The area where the cancer has returned must be vis...
NCT06985238 · Stratagen Bio, Inc. Not Applicable · 1 country
Who might be able to join this trial: - People whose prostate has been identified as one that a doctor would consider biopsying - People aged between 40 and 90 years old - People with a PSA blood test result of 2.5 or higher - People who have been fully informed about the study and have signed a consent form agreeing t...
NCT06990542 · University of California, San Diego Phase 2 · 1 country
**Who might be able to join this trial:** - People who are at least 18 years old - People who have signed and dated a consent form agreeing to take part - People who are willing and available to follow all study procedures for the full duration of the trial - People who have been diagnosed with prostate adenocarcinoma...
NCT06990880 · GlaxoSmithKline Phase 2 · 5 countries
**Who might be able to join this trial:** - Men aged 18 or older who are able to read, understand, and sign a consent form agreeing to take part in the study. - Men who agree not to donate sperm during the treatment period and for at least 195 days after the last dose, and who agree to either remain completely abstine...
NCT06992232 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medic... Phase 2 · 1 country
Who might be able to join this trial: - People who have been confirmed through tissue or cell testing to have prostate adenocarcinoma (a specific type of prostate cancer), with cancer that has spread to distant parts of the body but to no more than 10 sites, detected using a specialised scan (PSMA PET/CT or PSMA PET/MR...
NCT06995053 · Jonsson Comprehensive Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has been confirmed by a tissue sample and appears to be contained to the local area - There is no sign that the cancer has spread to lymph nodes in the upper abdomen, bones, or other org...
NCT07001241 · University of Colorado, Denver Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 89 years old - People who have been diagnosed with breast cancer or prostate cancer - People who finished cancer treatment aimed at curing the cancer more than 3 months ago but less than 5 years ago - Treatment must have included hormone therapy, radiation,...
NCT07002320 · Institute of Cancer Research, United Kingdom Phase 2 · 2 countries
**Who might be able to join this trial:** - People who are able to give written consent and are able to cooperate with the treatment process. - People aged 18 or older. - People with a confirmed diagnosis of prostate adenocarcinoma (a specific type of prostate cancer), with tumour tissue available for research, or who...
NCT07004582 · Maastricht Radiation Oncology Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with prostate cancer - People who are scheduled for a specific internal radiation treatment (called HDR brachytherapy) for high-risk or returning prostate cancer, or who are scheduled for a needle biopsy...
NCT07005154 · Astellas Pharma Global Development, Inc. Phase 2 · 12 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a tissue or cell sample, specifically the type called adenocarcinoma, without certain rare aggressive features (neuroendocrine differentiation or small cell features). - People whose general health and ability...
NCT07006727 · Novartis Pharmaceuticals Phase 1 · 3 countries
Who might be able to join this trial: - Adults aged 18 or older - People with small cell lung cancer (SCLC) that has spread or cannot be surgically removed, where the cancer has continued to grow or worsened after at least one previous treatment (including a platinum-based chemotherapy, unless that type of treatment wa...
NCT07007910 · Haisco Pharmaceutical Group Co., Ltd. Phase 1 · 1 country
Who might be able to join this trial: - People who are male and aged 18 years or older - People whose general health and ability to carry out daily activities meets a certain standard, and who are expected to live for at least 3 months (confirm with trial site) - People whose prostate cancer has been confirmed by tissu...
NCT07014618 · University of Oklahoma Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with breast cancer or prostate cancer, confirmed through a tissue or cell sample test. - People who are 18 years of age or older. - People who identify as African American, Native American, or Hispanic. - People who are scheduled to receive radiatio...
NCT07015138 · Peking University First Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - You are a male aged between 18 and 85 years old - Your prostate cancer has been confirmed by a tissue biopsy as a specific type called acinar adenocarcinoma (certain minor variations of this cancer type are still allowed — confirm with trial site) - A special type of scan ca...
NCT07025369 · Mayo Clinic Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older. - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample test. - People whose prostate cancer has been classified as high risk or very high risk based on standard medical guideli...
NCT07027124 · Icahn School of Medicine at Mount Sinai Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older at the time of giving consent - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer) confirmed by a laboratory tissue test - People whose prostate cancer is classified as unfavorable intermediate or high-risk,...
NCT07038304 · University Medical Center Groningen Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a type of prostate cancer called adenocarcinoma. - People whose prostate cancer has spread to other parts of the body and is no longer responding to hormone therapy, with testosterone levels confirmed to be very low (below 50 ng/dl). - Peop...
NCT07042256 · University of Zurich Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with localised prostate cancer that a medical team has determined is suitable for a specific type of targeted radiation treatment called SBRT. - People who have artificial hip replacements on both sides that have been labelled as safe or conditional...
NCT07048314 · The Methodist Hospital Research Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People scheduled to have robotic-assisted laparoscopic prostate surgery (a type of minimally invasive prostate removal) performed by Dr. B. Miles at Houston Methodist - Men between the ages of 40 and 70 (inclusive) - People diagnosed with prostate cancer that has not spread...
NCT07050433 · Duke University Not Applicable · 1 country
Who might be able to join this trial: - People who are willing and able to sign a written consent form and authorize the release of their personal health information for this study - People who are over 18 years of age - People who are already participating in the SYNERGY-201 clinical trial Who may not be able to join...
NCT07052578 · AstraZeneca Not Applicable · 1 country
Who might be able to join this trial: - You must be a male aged 18 or older - You must be willing to sign a consent form, including agreeing to provide blood samples for DNA testing - You must have prostate cancer that has spread to other parts of the body and still responds to hormone treatment (either newly diagnosed...
NCT07054346 · Thomas Hope Phase 1 · 1 country
**Who might be able to join this trial:** - A diagnosis of prostate cancer that has been confirmed through tissue testing (biopsy). - Willingness to have the prostate surgically removed (with or without removal of nearby lymph nodes), and a surgical team has determined this is a suitable option. - High-risk prostate c...
NCT07055165 · University of Oklahoma Not Applicable · 1 country
Who might be able to join this trial: - You currently live in Oklahoma - You identify as Black or African American - You identify as male - You are between 45 and 69 years old - You have not been diagnosed with prostate cancer Who may not be able to join: - You are not willing or interested in using a phone app for 30...
NCT07057375 · Chinese University of Hong Kong Not Applicable · 1 country
**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed with prostate cancer that has been confirmed through a tissue sample (biopsy or surgery) - Your prostate cancer has not spread to distant parts of the body - You have been receiving hormone therapy (a treatment that lowe...
NCT07068555 · Shenzhen Geno-Immune Medical Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a laboratory tissue test - People who are generally healthy and active, or have only mild limitations in daily activity (this is measured by a standard medical scale...
NCT07071207 · University of Rochester Not Applicable · 1 country
Who might be able to join this trial: - People who are planning to have a radical prostatectomy (surgery to remove the prostate) or a laser procedure to remove prostate tissue - People who are patients at URMC Urology - Adult males aged 18 years or older - People who are able to read, write, and speak in English (the q...
NCT07073794 · Mayo Clinic Phase 2 · 1 country
**Who might be able to join this trial:** - You must be 18 years of age or older - You must be a Black or African American man with prostate cancer that is locally advanced, high risk, has come back (based on a PSA blood test), or has spread to other parts of the body - You must currently be receiving, or be about to...
NCT07077239 · Jonsson Comprehensive Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that was confirmed by a tissue biopsy, was contained to the prostate area, and you have already had surgery to remove the prostate (radical prostatectomy). - At least ONE of the following ap...
NCT07089550 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with advanced prostate cancer (a specific type that is not neuroendocrine carcinoma, which is a rarer form) - You are scheduled to have a PSMA PET scan to check how far your cancer has spread before starting treatment - You are being considered for one or...
NCT07093801 · Novartis Pharmaceuticals Not Applicable · 1 country
**Who might be able to join this trial:** - Adults who have been diagnosed with metastatic castration-resistant prostate cancer (a type of prostate cancer that has spread and no longer responds to hormone treatment) and whose treating medical team has assessed them as suitable and prescribed a specific treatment called...
NCT07096128 · Jinming Zhang Phase 1 · 1 country
**Who might be able to join this trial:** - You must be able to understand and sign a consent form agreeing to take part in the trial. - You must be between 18 and 80 years old. - You must be reasonably active and able to carry out daily activities with little or no limitation (confirm with trial site regarding exact...
NCT07096999 · University of Michigan Rogel Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who have been scheduled to receive a treatment called 177Lu-PSMA-617 for prostate cancer that has spread and is no longer responding to hormone therapy - People who have been assessed as clinically stable by their nuclear medicine doctors - People who are male - People who...
NCT07103018 · K36 Therapeutics, Inc. Phase 1 · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People who are fully active or have only minor restrictions in physical activity, as measured by a standard oncology performance scale (called ECOG score 0 or 1) - Male participants diagnosed with metastatic castration-resistant prostate cancer (a form...
NCT07109427 · Washington University School of Medicine Not Applicable · 1 country
Who might be able to join this trial: - People who receive their medical care within the BJC Health System - People who have had at least one appointment with a primary care doctor in the same calendar year as their PSA screening - People who are male - People who do not have a history of prostate cancer - People who f...
NCT07111507 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People whose blood oxygen level is 90% or higher while breathing normal room air - People who have been diagnosed with prostate cancer confirmed by a tissue sample (any type of prostate cancer is accepted) - People whose cancer has spread to other p...
NCT07112599 · Anhui Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 50 or older - People who have been diagnosed with a specific type of prostate cancer (prostate adenocarcinoma) confirmed through a tissue or cell sample - People whose PSA level is 20 ng/ml or higher, or whose cancer has a Gleason score of 8 or higher (a measure...
NCT07112781 · Branch Office of "Hadassah Medical Ltd" Not Applicable · 1 country
**Who might be able to join this trial:** - People who have signed a consent form specific to this study - People whose prostate cancer has been confirmed as adenocarcinoma (a specific type of prostate cancer) through a biopsy - People whose biopsy Gleason score (a measure of cancer aggressiveness) is 7 or lower - Peop...
NCT07115446 · Hansoh BioMedical R&D Company Phase 1 · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - People who are willing to take part and have signed and dated a consent form - People who have prostate cancer that has spread to other parts of the body, is no longer responding to hormone-lowering treatments (called castration-resistant), and h...
NCT07115914 · University of Chicago Not Applicable · 1 country
Who might be able to join this trial: - People who were assigned male at birth and are 18 years of age or older. - People who are able to understand the study information and sign a written consent form. - People who have been diagnosed with prostate cancer confirmed through a specific type of biopsy procedure, where t...
NCT07115992 · Ruijin Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men between 18 and 80 years of age who have signed and dated a consent form agreeing to take part. - Men who are able to commit to following the study's procedures throughout the entire trial. - Men who are healthy enough to undergo the procedures involved in the study, inclu...
NCT07130682 · Hong Kong Sanatorium & Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - Men under 18 years of age whose prostate cancer has been confirmed by a tissue biopsy and classified as low- or intermediate-risk according to established medical guidelines (NCCN) - People whose general physical health and ability to carry out daily activities meets a certa...
NCT07130708 · AdventHealth Not Applicable · 1 country
**Who might be able to join this trial:** - Adults between 18 and 90 years old, of any gender - People with a confirmed diagnosis of localised prostate cancer that a medical team has determined is suitable for robotic-assisted surgical removal of the prostate - People with a confirmed diagnosis of a non-cancerous (ben...
NCT07131956 · University of Erlangen-Nürnberg Medical School Not Applicable · 1 country
Who might be able to join this trial: **Arm 1 (first-time treatment group):** - People receiving their first treatment for prostate cancer using a specific type of radiation called I-125 seeds or high-dose-rate brachytherapy (a form of internal radiation) - People who have not had any previous treatment for prostate c...
NCT07142551 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 · 1 country
Who might be able to join this trial: - Adults aged 18 or older. - People with a general health status rated at a certain level, meaning they are reasonably able to carry out daily activities (confirm with trial site for specific performance status rating). - People who have been diagnosed with prostate cancer (a speci...
NCT07142967 · NYU Langone Health Not Applicable · 1 country
**Who might be able to join this trial:** - You are a male aged 18 or older - A biopsy has confirmed prostate cancer that has come back inside the prostate after you previously received external beam radiation therapy (a type of radiotherapy) - Your biopsy results show active, living cancer cells that can be graded by...
NCT07144228 · Duke University Not Applicable · 1 country
**Who might be able to join this trial:** - You are a man aged 40 or older - You are being seen at Duke Health/Urology and your doctor suspects you may have prostate cancer (but you have not been diagnosed yet) **Who may not be able to join:** - Men who have already been treated for prostate cancer at any point in the...
NCT07145255 · MBrace Therapeutics Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People who are able to read, understand, and sign a consent form, and who are willing and able to follow all study procedures - Women who are at least 2 years past menopause, or who have had a surgical procedu...
NCT07149831 · Sinotau Pharmaceutical Group Phase 1 · 1 country
Who might be able to join this trial: - People who are able to understand what the study involves and are willing to sign a consent form agreeing to take part. - Healthy men or women between 18 and 60 years of age (inclusive). - People whose body weight falls within a healthy range for their height, specifically a BMI...
NCT07156045 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Early Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with metastatic castration-resistant prostate cancer (prostate cancer that has spread and is no longer responding to hormone-lowering treatment) - People whose testosterone levels in the blood are very low, at a level consistent with castration...
NCT07156903 · Charite University, Berlin, Germany Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer and are receiving radiotherapy with the goal of curing the cancer - People who are at least 18 years old - People who have a sufficient understanding of the German language to take part in interviews - People who are able to giv...
NCT07162987 · Odense University Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer - People who are at least 18 years old - People who are receiving androgen deprivation therapy and radiation therapy as their treatment - People who live in Vejle Municipality or Esbjerg Municipality in Denmark - People who are...
NCT07163910 · baotai Liang Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 to 85 years old - People whose prostate cancer has been confirmed through a tissue or cell sample (biopsy or lab test) - People whose prostate cancer falls into one of these categories: high-risk or very high-risk cancer that has not spread to lymph nodes or o...
NCT07164027 · Jonsson Comprehensive Cancer Center Early Phase 1 · 1 country
**Who might be able to join this trial:** - Men between the ages of 18 and 90 at the time of enrolling in the study - People who have had an MRI scan in the past 12 months that showed at least one area of concern on the prostate, rated on a scale used by radiologists (called PI-RADS, scores 3 to 5) **Who may not be ab...
NCT07164456 · M.D. Anderson Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** **For cancer survivors:** - You are 18 years old or older - You identify as Black or African American - You were diagnosed with early to mid-stage prostate cancer (stage 0 through stage 3), including those being monitored without active treatment - You have finished your prost...
NCT07168616 · Istanbul University - Cerrahpasa Not Applicable · 1 country
**Who might be able to join this trial:** - People who had a specific type of prostate scan (called an mpMRI) within the 3 months before joining the trial - People who have had a prostate biopsy, either guided by the MRI scan or using the standard method - People whose biopsy confirmed a low-risk, early-stage prostate...
NCT07172685 · Qilu Hospital of Shandong University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing to take part and have signed a consent form agreeing to participate - Men aged 18 or older - People whose prostate cancer has been confirmed through a tissue or cell sample (biopsy or similar test) - People whose scans (bone scan, CT, or MRI) show eith...
NCT07179783 · Tianjin Medical University Second Hospital Phase 2 · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with a specific type of prostate cancer called AVPC or NEPC, based on recent tissue testing and/or clinical assessment - People who have previously received one o...
NCT07180381 · St. Antonius Hospital Not Applicable · 1 country
**Who might be able to join this trial:** - People with a life expectancy of more than 10 years - People whose PSA blood test result was below 20 ng/ml at the start - People with no signs that the prostate condition has spread beyond the prostate gland, based on a physical examination - People whose MRI scan results an...
NCT07182279 · The Methodist Hospital Research Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a biopsy showing a type called adenocarcinoma. - People whose scans (bone scan and CT scan, or a special PSMA-PET scan) show no signs that the cancer has spread to other parts of the body. - People whose cancer...
NCT07184970 · NYU Langone Health Not Applicable · 1 country
Who might be able to join this trial: - Men between 40 and 95 years of age who have been diagnosed with prostate cancer that has been confirmed by a biopsy and has not spread beyond the prostate. - People whose cancer has been graded at a certain level of aggressiveness (Grade Group 2 or higher, also known as a Gleason...
NCT07189403 · Daiichi Sankyo Phase 1 · 3 countries
**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with a specific type of cancer (either adrenocortical carcinoma or prostate adenocarcinoma), confirmed by a tissue sample test - You are reasonably active and able to care for yourself day-to-day, with only minor lim...
NCT07189871 · Radiopharm Theranostics, Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing and able to give their informed consent before any study procedures begin, and who are willing to follow all study requirements. - People who are 18 years of age or older. - People who have a confirmed diagnosis (proven by tissue biopsy) of one of the...
NCT07192120 · Minghui Pharmaceutical (Hangzhou) Ltd Phase 2 · 1 country
**Who might be able to join this trial:** - You are willing to take part and have signed the consent form agreeing to participate. - You are 18 years old or older (any gender can apply). - You are able to carry out daily activities with little to no limitation, as measured by a standard health scale (confirm with trial...
NCT07192614 · AstraZeneca Phase 2 · 9 countries
**Who might be able to join this trial:** - People who are able to give signed consent and are willing to follow the study rules and schedule. - People who are willing to sign a separate consent form related to optional genetic research. - People who are 18 years of age or older at the time of signing the consent form...
NCT07196488 · National Taipei University of Nursing and Health Sciences Not Applicable · 1 country
Who might be able to join this trial: **For patients:** - People who have been diagnosed with prostate cancer by a qualified urologist - People who have either already decided on a treatment plan or have finished treatment within the last two years - People who are generally healthy and able to carry out daily activit...
NCT07197723 · Memorial Sloan Kettering Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People who do not currently have prostate cancer (for those not being treated at the trial site, this may be based on self-report) - People aged between 45 and 70 years old - People who were assigned male sex at birth (for those not being treated at the trial site, this may be ba...
NCT07200830 · Alliance for Clinical Trials in Oncology Phase 3 · 1 country
Who might be able to join this trial: - People who have been confirmed through biopsy or lab testing to have prostate adenocarcinoma (a specific type of prostate cancer) - People who have had a specific type of nuclear imaging scan (PSMA PET/CT) that showed positive results, meaning the cancer showed up clearly on the...
NCT07201194 · Vejle Hospital Not Applicable · 1 country
Who might be able to join this trial: - You are 18 years old or older - You are currently receiving chemotherapy and are still feeling nauseous even though you are taking your prescribed anti-sickness medications as directed - You can understand and speak Danish - You are willing and able to give your consent to take p...
NCT07203482 · NYU Langone Health Not Applicable · 1 country
**Who might be able to join this trial:** - People who are male and between the ages of 40 and 95 - People who have prostate cancer that is contained within the prostate, confirmed by MRI scan and biopsy - People whose prostate cancer has not spread outside the prostate, and who have chosen a treatment called focal HIF...
NCT07209878 · First Affiliated Hospital of Fujian Medical University Phase 3 · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a biopsy - People who have not received any cancer treatment before the PET scan involved in this trial - People who are willing and able to follow all the requirements of th...
NCT07210086 · City of Hope Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - Adults aged 18 or older who have given their written consent to participate (or whose legal representative has done so on their behalf) - People who are in reasonably good general health, able to carry out normal daily activities with little or no difficulty (confirm with tr...
NCT07218718 · City of Hope Medical Center Not Applicable · 1 country
Who might be able to join this trial: - The person must be an English speaker - The person must be reasonably well and able to carry out daily activities (assessed using a standard medical scale called ECOG, with a score below 2 — confirm with trial site if unsure what this means) - The person must have a diagnosis of...
NCT07219147 · City of Hope Medical Center Phase 1 · 1 country
**Who might be able to join this trial:** - People who have given written consent to take part (or whose legal representative has done so on their behalf) - People who agree to allow stored tumour tissue from a previous biopsy to be used for the study (exceptions may be possible with approval from the study's lead doc...
NCT07219303 · Fox Chase Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (adenocarcinoma) confirmed by a tissue biopsy, at an intermediate or favorable high-risk stage (classified as stage IIA–IIC under a specific staging system) - People aged 18 or older - People whose general physical health a...
NCT07220720 · University of Florida Phase 2 · 1 country
**Who might be able to join this trial:** - You are willing to sign a consent form and are able to follow all the steps required by the study. - You are male and at least 18 years old. - You have never had a prostate biopsy before. - You had a special type of MRI scan of your pelvis (called an mpMRI) within the last 90...
NCT07222436 · University of Pittsburgh Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a laboratory test of tissue samples - People aged 18 years or older - People who are fully active or have only minor restrictions in physical activity (this is measured by a standard scale called ECOG; scores 0...
NCT07223385 · Cedars-Sinai Medical Center Phase 2 · 1 country
Who might be able to join this trial: - People who have prostate cancer that is localised, very high risk, has spread to nearby lymph nodes, or has spread to other parts of the body (Stage IV). - People who are currently being treated with a type of hormone-based cancer therapy called an androgen receptor pathway inhib...
NCT07231159 · AdventHealth Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - People seeking care at a participating clinic or emergency department - People who meet the screening criteria for at least one of the following cancers: lung cancer (adults aged 50 to 80 who have smoked at least 20 pack-years and currently smoke or quit...
NCT07231627 · University of Arkansas Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 40 years of age or older - People who have had a prostate MRI scan (pMRI) within the last 12 weeks - People whose general health and activity level falls within a certain range, rated 0 or 1 on a standard scale used by doctors (confirm with trial site) - Peopl...
NCT07237269 · University of Nebraska Phase 2 · 1 country
Who might be able to join this trial: - People who have been diagnosed with localised prostate cancer, confirmed through tissue testing (biopsy). - People who have a lymph node in the pelvic area that shows up on a PSMA scan and measures less than 1 centimetre across at its narrowest point. - People who have not yet re...
NCT07242014 · The First Affiliated Hospital of Xiamen University Not Applicable · 1 country
Who might be able to join this trial: - You must be 18 years of age or older - You have been newly diagnosed with prostate cancer that has spread to other parts of the body, or your doctor suspects your cancer has come back, or you have previously been treated for prostate cancer that has spread (evidence may include s...
NCT07243834 · Royal Marsden NHS Foundation Trust Not Applicable · 1 country
**Who might be able to join this trial:** - People who are 18 years of age or older at the time of joining the trial - Men who have been diagnosed with prostate cancer (confirmed by a tissue sample) and are currently receiving or are planned to receive a hormone therapy called ADT (androgen deprivation therapy) using...
NCT07244341 · Daiichi Sankyo Phase 1 · 4 countries
Who might be able to join this trial: - Men aged 18 or older at the time of signing the consent form (or older if local laws require a higher age of consent for trial participation). - People with a confirmed diagnosis of prostate adenocarcinoma (a specific type of prostate cancer confirmed through tissue testing), inc...
NCT07247175 · Seong Soo Jeon Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 19 years or older - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy), at an early to moderate stage (T1 to T3a, with no spread to lymph nodes or other parts of the body) - People who are scheduled to have a robot-assisted surg...
NCT07250542 · baotai Liang Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 years or older but under 85 years old - People whose prostate cancer has not responded to at least one chemotherapy treatment containing docetaxel, and at least one standard hormone-based therapy - People diagnosed with castration-resistant prostate cancer (CR...
NCT07252726 · Ottawa Hospital Research Institute Phase 4 · 1 country
**Who might be able to join this trial:** **Breast Cancer Group (Cohort A):** - People who have breast cancer that has spread to other parts of the body, and whose cancer is driven by hormones (hormone receptor positive) - People whose doctor plans to treat them with hormone therapy and a specific type of targeted the...
NCT07255664 · CuraCell TX AB Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a consent form agreeing to take part in the trial before any trial procedures begin. - People who are 18 years of age or older at the time of signing the consent form. - People who live within 50 km of a hospital that can provide care during the trial....
NCT07260435 · Nick Beije Phase 3 · 1 country
Who might be able to join this trial: - People who are male and at least 18 years old - People who are able to understand the trial requirements and sign a consent form - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through a tissue sample - People whose ca...
NCT07271017 · Johns Hopkins University Phase 1 · 1 country
**Who might be able to join this trial:** - Men between the ages of 40 and 75 - Men who have at least one of the following risk factors: a PSA blood test result above 4.0 ng/ml, an abnormal prostate exam performed by a doctor using their finger (called a digital rectal exam), or a previous biopsy that found unusual but...
NCT07282808 · Singapore General Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a specific type of prostate cancer called prostate adenocarcinoma - People whose cancer falls within a mid-range severity level (Grade Group 2, 3, or 4 out of 5) - People whose cancer lesion, as seen on MRI scan, is small — no larger than 3ml f...
NCT07285694 · Arsenal Biosciences, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - You must be at least 18 years old at the time you sign the consent form - You have been diagnosed with prostate cancer (adenocarcinoma type) that has been confirmed by a tissue sample (biopsy) - Your prostate cancer has spread to other parts of the body (metastatic), is no l...
NCT07290270 · Novartis Pharmaceuticals Not Applicable · 1 country
Who might be able to join this trial: - Adults who are male and have been diagnosed with either metastatic castration-resistant prostate cancer (a form of prostate cancer that has spread and no longer responds to hormone therapy) or metastatic hormone-sensitive prostate cancer (a form of prostate cancer that has spread...
NCT07292168 · Kidney Cancer Research Bureau Phase 2 · 1 country
**Who might be able to join this trial:** - You have signed and dated a consent form agreeing to take part in the study voluntarily - You are 18 years old or older at the time of signing the consent form - You weigh at least 50 kg (about 110 lbs) - You have been diagnosed with one of the following cancers that has spr...
NCT07293585 · Jonsson Comprehensive Cancer Center Phase 3 · 1 country
Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has been confirmed by a tissue sample and has not spread beyond the prostate area - People who have had the recommended scans and tests to as...
NCT07296887 · Washington University School of Medicine Not Applicable · 1 country
Who might be able to join this trial: **For healthcare and support staff ("Implementation Champions"):** - You work as part of a cancer care team (such as a doctor, nurse, research coordinator, financial navigator, or social worker) supporting patients with gynecologic, lung, prostate, or colorectal cancer, OR you wor...
NCT07298239 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Early Phase 1 · 1 country
Who might be able to join this trial: - People who are male and aged 18 or older - People who have been diagnosed with prostate cancer that has spread to other parts of the body and is no longer responding to hormone therapy (castration-resistant), confirmed by very low testosterone levels in the blood - People whose c...
NCT07300631 · Sheffield Teaching Hospitals NHS Foundation Trust Not Applicable · 2 countries
**Who might be able to join this trial:** - People who have been clinically diagnosed with prostate cancer and are planned to receive treatment aimed at curing the condition at one of the selected trial sites in the UK or France, where a SpaceOAR device is already being used as part of their standard care. - People age...
NCT07308990 · N.N. Alexandrov National Cancer Centre Not Applicable · 1 country
Who might be able to join this trial: - People who are over 18 years old - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, without a neuroendocrine component) confirmed through laboratory testing of tissue - People whose cancer has not spread to other parts of the body - Peop...
NCT07311694 · Jiangsu HengRui Medicine Co., Ltd. Phase 3 · 1 country
**Who might be able to join this trial:** - People who are willing to take part, understand what the study involves, and are able to sign a written consent form - People who are male and aged 18 years or older - People whose general health and ability to carry out daily activities meets a specific standard set by doct...
NCT07313241 · University of Texas Southwestern Medical Center Phase 2 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older who have been diagnosed with prostate cancer (confirmed by tissue biopsy) and had their prostate surgically removed to treat localised cancer within the past 10 years, and whose PSA level after surgery is 0.05 ng/mL or higher (either remaining elevated o...
NCT07319871 · Janssen Research & Development, LLC Phase 1 · 2 countries
**Who might be able to join this trial:** - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a laboratory test on tissue. Certain rare types of prostate cancer are not allowed, but adenocarcinoma with some mixed features may still be eligible (confirm with...
NCT07324798 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a urological (urinary system or related organ) tumour that is either newly diagnosed, has spread to other parts of the body, or has come back, and where the diagnosis has been confirmed through laboratory testing of tissue - People whose medica...
NCT07325721 · Medical University of South Carolina Phase 2 · 1 country
**Who might be able to join this trial:** - People who are willing to sign and date a consent form agreeing to take part in the study. - People who are willing and able to follow all study procedures for the full duration of the trial. - Biologically male patients aged 18 years or older. - People who are able to recei...
NCT07332000 · Candel Therapeutics, Inc. Phase 2 · 1 country
**Who might be able to join this trial:** - People who have given their written agreement to take part in this specific study before enrolling - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed through a tissue sample test - People whose prostate cancer is classifi...
NCT07332455 · GlaxoSmithKline Phase 2 · 4 countries
**Who might be able to join this trial:** - People who have metastatic castration-resistant prostate cancer (prostate cancer that has spread and no longer responds to hormone-lowering treatment), confirmed by a laboratory test of tissue or cells showing a specific type called adenocarcinoma. - People whose prostate can...
NCT07333066 · Alianza multidisciplinar para la investigación de los tumores genitour... Phase 3 · 5 countries
Who might be able to join this trial: - People who have signed a consent form showing they understand the study and agree to take part - Men aged 18 or older - People who have been diagnosed with prostate cancer confirmed by a tissue or cell sample, specifically the type called adenocarcinoma - People whose prostate ca...
NCT07334275 · Radboud University Medical Center Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 years or older - People who have been diagnosed with high-risk prostate cancer, which the trial defines in one of two ways: either high-risk cancer that is still contained within or near the prostate (based on specific PSA levels, biopsy scores, or...
NCT07335224 · Inova Health Care Services Not Applicable · 1 country
**Who might be able to join this trial:** - People who are male - People who are at least 18 years old - People who have been diagnosed with prostate cancer (adenocarcinoma) at any stage (Stage I through Stage IV), confirmed through a tissue or cell sample test - People who are currently receiving hormone-blocking trea...
NCT07339267 · Astellas Pharma Global Development, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma, confirmed by laboratory testing of tissue or cells, without certain aggressive features). - People whose general health and ability to carry out daily activities falls within a certai...
NCT07343349 · Rigshospitalet, Denmark Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy, with no signs that the cancer has spread to distant parts of the body - People whose prostate cancer is classified as intermediate or high risk, based on at least one of the following: the cancer ha...
NCT07344363 · Centro di Riferimento Oncologico - Aviano Not Applicable · 1 country
**Who might be able to join this trial:** - People who are currently being treated with one of the following medications: abiraterone, apalutamide, darolutamide, or enzalutamide, taken at the doses specified in the official medication guidelines, and whose body levels of the medication have reached a stable, consistent...
NCT07344844 · Clinique Sainte Clotilde Not Applicable · 1 country
Who might be able to join this trial: - Men aged 60 years or older - People diagnosed with prostate cancer that is contained within the prostate (has not spread) and is classified as low or intermediate risk (stages T1 or T2) - People whose prostate cancer has a Gleason score of 6 or 7 (a measure of how the cancer cell...
NCT07348367 · Henry Ford Health System Not Applicable · 1 country
**Who might be able to join this trial:** - People with prostate cancer who are being treated at Henry Ford Health by the trial's lead or co-investigator, and who have chosen surgery as their treatment. - People whose PSA (a prostate-related protein measured in the blood) is 20 or below. - People whose cancer is at an...
NCT07351461 · University Hospital, Lille Not Applicable · 1 country
Who might be able to join this trial: - People who are 18 years of age or older. - People who began active monitoring (instead of immediate treatment) for prostate cancer that had not spread beyond the prostate, starting sometime between 2007 and 2023, and who are currently being followed up at the Urology Department o...
NCT07357259 · IRCCS Azienda Ospedaliero-Universitaria di Bologna Not Applicable · 1 country
**Who might be able to join this trial:** - People who have recently been diagnosed with prostate cancer and are in the process of having their cancer staged (assessed for spread) - People whose prostate cancer has shown signs of returning through a rise in PSA blood test levels after previously receiving surgery and/...
NCT07363382 · First Affiliated Hospital of Fujian Medical University Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer, whether or not they have already received treatment for it - People who have signed a written consent form agreeing to take part **Who may not be able to join:** - People who have a known allergy to PSMA (a protein found o...
NCT07365423 · Swiss Cancer Institute Phase 2 · 1 country
**Who might be able to join this trial:** - People who have already completed a full course of treatment for localised prostate cancer (such as surgery to remove the prostate, radiation therapy, or brachytherapy), and where standard curative treatment options have been exhausted - People who have previously had target...
NCT07365995 · BioNTech SE Phase 3 · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 or older (or meet the minimum age required by local rules at the time of agreeing to join). - People who have prostate cancer that has been confirmed to be getting worse, shown by rising PSA blood test results, new or growing soft tissue tumou...
NCT07369570 · University of Eastern Finland Not Applicable · 1 country
**Who might be able to join this trial:** - People who are suspected of having localised prostate cancer (cancer that has not spread beyond the prostate) - People who have 1 or 2 areas of concern (rated PI-RADS 3–5) seen on a specific type of prostate MRI scan called a biparametric MRI - People whose initial biopsy (e...
NCT07370597 · Jules Bordet Institute Not Applicable · 1 country
Who might be able to join this trial: - People who are male, aged 18 or older, and have been diagnosed with prostate cancer (a specific type called adenocarcinoma). - People whose prostate cancer has spread to other parts of the body and is getting worse, shown by two rising PSA blood test results in a row, or by chang...
NCT07391982 · The Netherlands Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 18 years or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a tissue sample, where the treating doctor has recommended radiation treatment to the whole prostate - People whose cancer has a Gleason scor...
NCT07393867 · Martin T. King, MD, PhD Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People whose general health and ability to carry out daily activities meets a standard medical performance rating of 0 or 1 (meaning fully active or able to carry out light activity) — confirm with trial site if unsure - People who have been d...
NCT07395804 · Bayer Not Applicable · 1 country
Who might be able to join this trial: - People who are male and aged 18 years or older - People who have been diagnosed with metastatic hormone-sensitive prostate cancer (a type of prostate cancer that has spread to other parts of the body and still responds to hormone treatment), confirmed through a tissue or cell sam...
NCT07398690 · In Gab Jeong, MD Not Applicable · 1 country
**Who might be able to join this trial:** - People who are male and aged 20 years or older - People whose PSA blood test result is between 3.0 and 20.0 ng/mL, or who have had an abnormal prostate examination by a doctor (confirm with trial site) - People who have never had a prostate biopsy before - People whose cancer...
NCT07406282 · Bayer Not Applicable · 1 country
Who might be able to join this trial: - People who are male and were newly diagnosed with prostate cancer that had already spread to other parts of the body at the time of diagnosis (known as de novo metastatic hormone-sensitive prostate cancer) - People who started a specific type of prostate cancer hormone therapy ca...
NCT07407283 · Jiangsu HengRui Medicine Co., Ltd. Phase 2 · 1 country
Who might be able to join this trial: - People who are male and between 18 and 85 years old at the time of signing the consent form (the upper age limit is 80 years during the early dose-finding phase of the trial). - People whose general health and ability to carry out daily activities is rated as fully active or rest...
NCT07407608 · University of Milano Bicocca Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a tissue sample test - People whose prostate cancer is classified as intermediate or high risk, based on a standard medical risk system called NCCN - People who have a suspici...
NCT07407959 · Mayo Clinic Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 or older - For the prostate group: people referred for a prostate MRI for screening purposes who have not had any prior prostate-related treatment or biopsy - For the endometriosis group: people referred for evaluation of possible endometriosis before surgery Who...
NCT07410494 · Essen Biotech Phase 2 · 1 country
**Who might be able to join this trial:** - People between 18 and 75 years of age. - People who have an advanced, inoperable, or spread (metastatic) solid tumour that has stopped responding to standard treatments, has come back after treatment, or where no standard treatment exists. - People whose tumour tissue or blo...
NCT07414940 · University College, London Phase 2 · 1 country
**Who might be able to join this trial:** - People aged 18 or older at the time of giving consent to participate. - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through laboratory testing of tissue or cell samples, including cases with small cell or neuroe...
NCT07422597 · Norwegian University of Science and Technology Not Applicable · 1 country
Who might be able to join this trial: - People expected to live more than 10 more years - People with suspected prostate cancer that has not spread beyond the prostate gland - People whose physical prostate examination (a test where a doctor checks the prostate by touch) shows a suspicious finding at a stage called cT2...
NCT07424547 · Conjupro Biotherapeutics, Inc. Phase 1 · 1 country
**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing the consent form - You have been diagnosed with an advanced, inoperable, or spreading (metastatic) solid tumour, confirmed by a tissue or cell sample, and your cancer has come back or gotten worse during or after standa...
NCT07426055 · Affidea Nu-med Center of Oncological DIagnostics and Therapy Phase 3 · 1 country
**Who might be able to join this trial:** - Men aged 18 or older - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy) - People whose prostate cancer is contained within or close to the prostate, with no spread to nearby lymph nodes or other parts of the body, based on a speci...
NCT07426094 · Affidea Nu-med Center of Oncological DIagnostics and Therapy Phase 3 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer confirmed by a tissue biopsy, specifically the type called adenocarcinoma. - People whose prostate cancer has spread to nearby lymph nodes in the pelvis, but not to other parts of the body. - People whose affected lymph nod...
NCT07427043 · Brigham and Women's Hospital Phase 3 · 1 country
Who might be able to join this trial: - You are a man aged 45 or older - You are scheduled to have a type of prostate removal surgery using a robotic-assisted technique at Brigham and Women's Hospital (BWH) or Brigham and Women's Faulkner Hospital (BWFH) - You are able to understand and sign a consent form agreeing to...
NCT07432360 · Virdx, Inc. Not Applicable · 1 country
Who might be able to join this trial: - People who have a prostate and are 18 years of age or older. - People who have been diagnosed with prostate cancer through a biopsy and are scheduled to have their prostate surgically removed. - People who have read and signed a consent form showing they understand what the study...
NCT07436078 · Barbara Ann Karmanos Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - People who are already enrolled in a research study called the Detroit Research on Cancer Survivors (Detroit ROCS) - People who were diagnosed with breast cancer, prostate cancer, or colorectal cancer on or after January 1, 2013 - People who have received or are currently re...
NCT07441889 · University of Virginia Phase 2 · 1 country
Who might be able to join this trial: - People who are willing and able to sign a consent form and take part in all study activities for the full duration of the trial - People aged 18 or older at the time of signing the consent form - People whose doctor estimates they are expected to live for at least 3 months - Peop...
NCT07450599 · Bayer Phase 2 · 1 country
Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with localised prostate adenocarcinoma (a specific type of prostate cancer), have not previously taken the drug darolutamide, and are planning to have their prostate s...
NCT07451002 · Janssen Cilag S.A.S. Not Applicable · 1 country
**Who might be able to join this trial:** - People who were born male (based on chromosomal composition at birth) and are 18 years of age or older - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed through laboratory testing of tissue or cell samples - People...
NCT07451795 · Fudan University Phase 2 · 1 country
Who might be able to join this trial: - People aged between 18 and 80 years old. - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has spread to other parts of the body, confirmed by a tissue or cell sample, and detected by bone scan, CT, or MRI. - People who have had, o...
NCT07455058 · Francis Medical Inc. Not Applicable · 1 country
Who might be able to join this trial: - People who a doctor has determined are a suitable candidate for Vanquish therapy, or who have already completed a company-sponsored study involving Vanquish therapy. - People who are willing and able to sign a written consent form agreeing to take part. Who may not be able to jo...
NCT07455903 · Baptist Health South Florida Phase 2 · 1 country
**Who might be able to join this trial:** - People who have signed a consent form before the study begins - Men aged 18 years or older - People whose general health and ability to carry out daily activities meets a certain level of functioning (confirm with trial site what this means for a specific situation) - People...
NCT07463092 · University of Sao Paulo Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged 40 years or older - People who have been diagnosed with localised prostate cancer confirmed by a tissue or cell sample test - People who have been receiving treatment to lower testosterone levels — either through surgical removal of the testicles or hormone-blocking...
NCT07463833 · UNC Lineberger Comprehensive Cancer Center Not Applicable · 1 country
Who might be able to join this trial: **For healthcare providers:** - Providers who are 18 years of age or older - Providers who attend peer-review meetings at the clinics taking part in the trial **For patients:** - Patients who are 18 years of age or older - Patients with prostate cancer who are receiving radiation...
NCT07468708 · FindCure Biosciences (ZhongShan) Co., Ltd. Early Phase 1 · 1 country
Who might be able to join this trial: - You must be willing to take part in the study and sign a consent form agreeing to participate - You must be 18 years old or older - Group A: You may be eligible if you are a healthy person with no relevant medical conditions - Group B: You may be eligible if you have been diagnos...
NCT07468903 · Jonsson Comprehensive Cancer Center Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a tissue sample taken within the past 90 days - People whose prostate cancer has been identified on a specialised MRI scan (called a multiparametric MRI) - People whose c...
NCT07477626 · Sun Yat-sen University Phase 3 · 1 country
**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a tissue biopsy or sample - People who have had their prostate surgically removed (radical prostatectomy) along with nearby lymph nodes, and...
NCT07484971 · Société Algérienne de Formation et Recherche en Oncologie Not Applicable · 1 country
Who might be able to join this trial: - People aged 19 years or older. - People who have been diagnosed with prostate cancer confirmed through a tissue sample (biopsy) and/or biological testing. - People whose cancer care is being managed within one of the oncology departments taking part in this trial. - People who ha...
NCT07493512 · Amgen Phase 1 · 1 country
Who might be able to join this trial: - People who have been confirmed through laboratory testing (tissue or cell samples) to have prostate adenocarcinoma (a specific type of prostate cancer), but not a mixed type that includes a neuroendocrine component. - People who have prostate cancer that has spread to other parts...
NCT07500701 · Samsung Medical Center Phase 3 · 1 country
**Who might be able to join this trial:** - People who have had surgery to fully remove the prostate (called a radical prostatectomy) to treat prostate cancer - People aged 20 years or older - People whose PSA blood test levels remain elevated after prostate removal surgery — specifically, levels between 0.1 and 1.0 ng...
NCT07504835 · OHSU Knight Cancer Institute Not Applicable · 1 country
**Who might be able to join this trial:** - You are 65 years of age or older - You have been diagnosed with prostate cancer that was confirmed through a tissue sample (biopsy) - You finished surgery, chemotherapy, radiation, or other cancer treatments (not including hormone therapy) more than 3 months ago - You are exp...
NCT07516886 · Lithuanian University of Health Sciences Not Applicable · 1 country
Who might be able to join this trial: - The person must be a biological adult male. - The person must have prostate cancer that has been confirmed through tissue examination and has not yet been treated. - The person must be scheduled to have their prostate removed through open surgery, keyhole surgery, or robot-assist...
NCT07520916 · Giresun University Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer and are scheduled to have their prostate surgically removed (whether by open surgery, keyhole surgery, or robotic-assisted surgery) - People aged 18 years or older - People whose surgery is planned to take place at one of the st...
NCT07531329 · Xijing Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are suspected of having prostate cancer and have a PSA blood test result of 4.0 ng/mL or higher - People who have a specific type of nuclear imaging scan called a PSMA PET scan (including a delayed phase image) before having a prostate biopsy - People who are willing t...
NCT07535541 · University of Virginia Not Applicable · 1 country
**Who might be able to join this trial:** - People who are willing to sign and date a consent form agreeing to take part - People who are willing to follow all study procedures and are available for the full duration of the study - People who are male (biological sex) and aged 18 or older - People who have been diagno...
NCT07537010 · Chunjing Yu Phase 1 · 1 country
Who might be able to join this trial: - People who are able to understand the study and are willing to sign a written consent form, and can attend all required visits and follow the study requirements - Men aged 18 years or older - People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate...
NCT07541911 · University College, London Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with a clinically significant form of prostate cancer that can be treated with surgery, at a specific stage where the cancer has not spread to nearby lymph nodes or other parts of the body. - People who are healthy enough to undergo a type of prosta...
NCT07543055 · Regeneron Pharmaceuticals Phase 1 · 1 country
Who might be able to join this trial: - People who have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed by a tissue or cell sample, where the cancer is no longer responding to hormone treatment — but not a pure small cell type. - People whose prostate cancer has spread to other parts o...
NCT07543757 · Sequenom, Inc. Not Applicable · 1 country
Who might be able to join this trial: - Men aged between 40 and 75 years old at the time of joining the trial - People who are willing to sign and date a consent form agreeing to take part - People who have had a standard PSA blood test result between 2 and 10 ng/mL within the last 30 days (a PSA test is a blood test u...
NCT07545811 · Janux Therapeutics Phase 1 · 1 country
Who might be able to join this trial: - People who are male and aged 18 or older at the time of signing the consent form - People who have been diagnosed with prostate cancer (adenocarcinoma type), confirmed through laboratory testing of tissue or cell samples - For the dose escalation part of the trial: People whose p...
NCT07552168 · Cancer Trials Ireland Phase 2 · 2 countries
Who might be able to join this trial: - People who have signed a written consent form before any study procedures begin - Men aged 18 years or older - People whose general physical functioning falls within a certain range, meaning they are able to carry out at least some daily activities independently (confirm with tri...
NCT07552285 · The First Affiliated Hospital of Soochow University Not Applicable · 1 country
Who might be able to join this trial: - You have been assessed by a doctor who suspects you may have prostate cancer, and your PSA blood test levels are higher than normal. - You have no history of any other type of cancer. - You are able to have an MRI scan, meaning you do not have claustrophobia, a pacemaker, heart s...
NCT07553754 · Xijing Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer through a tissue sample test (biopsy) and are scheduled to have a PSMA PET scan (a type of imaging scan that looks for prostate cancer in the body). - People who have the PSMA PET scan done before receiving any treatment for pro...
NCT07553780 · Xijing Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who have recently been diagnosed with prostate cancer confirmed by a tissue sample, with a Gleason score of 7 or higher (indicating clinically significant cancer) - People who are planned to receive treatment aimed at curing the cancer, such as surgical removal of the pros...
NCT07559201 · Guilin Medical University, China Not Applicable · 1 country
Who might be able to join this trial: - Adults aged 18 years or older - People with prostate cancer that has spread to other parts of the body, whether newly diagnosed, suspected to have come back, or previously treated — supported by scans, blood markers, or biopsy results - People who have been scheduled to have both...
NCT07562438 · First Affiliated Hospital of Fujian Medical University Phase 2 · 1 country
Who might be able to join this trial: - People who have prostate cancer that has spread to other parts of the body and continues to grow despite having very low testosterone levels (a condition called metastatic castration-resistant prostate cancer, or mCRPC), shown by rising PSA levels or new growths visible on scans....
NCT07567521 · C Ray Therapeutics Phase 2 · 1 country
**Who might be able to join this trial:** - People who are able to understand and sign a consent form agreeing to take part in the study. - People who have been confirmed through tissue or cell testing to have a type of prostate cancer called adenocarcinoma. - People whose prostate cancer has spread and is no longer r...
NCT07580196 · University of Turin, Italy Not Applicable · 1 country
Who might be able to join this trial: - Male patients aged 18 years or older - People with prostate cancer that has been confirmed by tissue testing and is considered high-risk, based on at least one of the following: a high aggressiveness score (ISUP Grade Group 4 or 5); scan findings suggesting the cancer may be spre...
NCT07591701 · M.D. Anderson Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - You have been diagnosed with prostate cancer and receive your care at LBJ Hospital - You are eligible for an open prostate cancer clinical trial at LBJ Hospital during the time the study is running - You are able to understand and agree to take part by giving informed consent Wh...
NCT07597798 · University College, London Not Applicable · 1 country
**Who might be able to join this trial:** - Men aged between 18 and 79, from any ethnic background, who have been diagnosed with a specific stage of prostate cancer (classified as cT2–T3a, with no spread to nearby lymph nodes or other parts of the body) - People who had a specialised prostate MRI scan (called an mpMRI...
NCT07600554 · Philogen S.p.A. Phase 1 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer and fall into one of these groups: cancer that is suspected to have spread and are being considered for initial treatment; rising PSA levels suggesting the cancer may have returned (confirmed PSA level above 0.2 ng/mL); or...
NCT07614256 · Guangxi Medical University Not Applicable · 1 country
**Who might be able to join this trial:** - People who are scheduled to have, or have already had, a prostate biopsy or surgical removal of the prostate. - People who have already completed standard pre-procedure scans, specifically a multiparametric MRI and a transrectal ultrasound of the prostate. - People whose full...
NCT07621692 · National Taiwan University Hospital Phase 1 · 1 country
Who might be able to join this trial: - People aged 20 years or older who are able to understand and agree to the study requirements, including blood tests and scans - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has spread to other parts of the body and is no longer...
NCT07623941 · Columbia University Not Applicable · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that is contained within the prostate, confirmed through a biopsy guided by MRI and ultrasound imaging - People whose cancer is at a specific stage (T2cN0M0, meaning the cancer is in...
NCT07626151 · Nazmy Edward Seif Not Applicable · 1 country
Who might be able to join this trial: - People who are male and scheduled to have their prostate removed using a robot-assisted surgical procedure - People with a general health rating of ASA I, II, or III (a scale used by anaesthetists to classify overall fitness for surgery, ranging from very healthy to having severe...
NCT07635238 · Memorial Sloan Kettering Cancer Center Phase 2 · 1 country
**Who might be able to join this trial:** - You must have been confirmed through a biopsy to have a type of prostate cancer called prostate adenocarcinoma - Your cancer must be a Grade Group of 1, 2, or 3 (meaning low to intermediate risk, not the highest grade) - Your PSA level (a prostate cancer blood test) must hav...
NCT07641049 · Beijing Biotech Phase 1 · 1 country
**Who might be able to join this trial:** - People who are male and aged 18 years or older - People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma) that has spread to other parts of the body and is no longer responding to hormone-lowering treatments - People whose cancer has contin...
NCT07643415 · Hitit University Not Applicable · 1 country
**Who might be able to join this trial:** - You are male and 18 years of age or older - You have been diagnosed with a non-cancerous enlarged prostate (commonly called BPH — benign prostatic hyperplasia) - You are already scheduled to have an open surgical procedure to remove part of the prostate (called an open simple...
NCT07645391 · University of Michigan Rogel Cancer Center Not Applicable · 1 country
Who might be able to join this trial: - People aged between 35 and 70 years old - People who are able to understand and agree to take part in the trial (give informed consent) - People who, if they have another cancer, are expected to live more than 5 years - People who carry a known gene change (mutation) linked to pr...
NCT07645872 · EDAP TMS S.A. Not Applicable · 1 country
Who might be able to join this trial: - You are currently receiving treatment for prostate cancer using a specific medical device called the Focal One - You are willing to agree to having your medical information collected and stored as part of a registry Who may not be able to join: - You are currently in prison or h...
NCT07672119 · Bayer Not Applicable · 1 country
Who might be able to join this trial: - People who are male and have been diagnosed with prostate cancer - People who have had at least 2 prescription records for either enzalutamide or darolutamide during a specific time period identified by the trial - People who had a diagnosis of either hormone-sensitive prostate c...
NCT07686016 · Affidea Nu-med Center of Oncological DIagnostics and Therapy Not Applicable · 1 country
Who might be able to join this trial: - People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy) showing a specific type called adenocarcinoma. - People who are male. - People who are 18 years of age or older. - People whose prostate cancer had already spread to other parts of the body...
NCT07689656 · Union Hospital, Tongji Medical College, Huazhong University of Science... Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been fully informed about the study and have signed a written consent form before any study procedures begin - People aged 18 years or older - People who are in generally good health and able to carry out normal daily activities with little to no limitation (...
NCT07691697 · Affidea Nu-med Center of Oncological DIagnostics and Therapy Not Applicable · 1 country
**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with prostate cancer - People whose prostate cancer has spread to other parts of the body and is either still responding to hormone therapy, or is no longer responding to hormone therapy - People who are currently...
NCT07693075 · Ain Shams University Phase 2 · 1 country
Who might be able to join this trial: - A tissue biopsy has confirmed a diagnosis of prostate cancer of a specific type called adenocarcinoma. - The prostate cancer has been classified as "High-Risk" or "Very High-Risk" based on established medical guidelines — for example, the cancer has spread beyond the prostate, a...
NCT07710807 · Ankara Etlik City Hospital Not Applicable · 1 country
Who might be able to join this trial: - People who are male and between 50 and 75 years old. - People who have had a prostate MRI scan that showed a suspicious area rated as PI-RADS 3, 4, or 5 (a scoring system used to describe how concerning a finding looks on the scan). - People whose doctor has determined that a pro...
NCT07717268 · Instituto de Investigación en Oncología Radioterápica - Fundación Espa... Phase 2 · 1 country
**Who might be able to join this trial:** - People who have been diagnosed with a specific type of prostate cancer called adenocarcinoma, confirmed by a biopsy. - People whose testosterone levels are very low (in the "castration" range, below 50 ng/ml or 1.7 nmol/L), meaning hormone therapy is keeping testosterone sup...
Advocacy and support in Australia
Organisations that can offer information, support, or connection for Prostate Cancer. Where more than one is listed, they serve different needs or regions, so choose whichever fits your situation.
The Prostate Cancer Foundation of Australia is the national body for prostate cancer support.
This is a starting point, not medical advice or an endorsement. Contact details change; search the organisation name to find its current website.