Phase 2 study for people with Prostate Cancer
Recruiting Phase 2
This trial at a glance
Where this trial is running
| Site | City | State or country | Status at this site |
|---|---|---|---|
| Chris O'Brien Lifehouse | Sydney | NSW | Not yet recruiting |
| Royal Prince Alfred Hospital | Sydney | NSW | Recruiting |
| Concord Repatriation General Hospital (CRGH) | Sydney | NSW | Recruiting |
voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice
Who can join
The official eligibility criteria
Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.
Inclusion Criteria:
1. Adults aged ≥18 years undergoing elective robot-assisted radical prostatectomy (RARP) with curative intent for confirmed prostate cancer.
2. Consulting a urological surgeon with an appointment at participating sites at least 4 weeks prior to scheduled surgery.
3. Willingness to engage in prescribed self-directed interventions.
4. Expected to have 100% unilateral OR \>50% bilateral nerve sparing at prostatectomy
Exclusion Criteria:
1. Cognitive impairment such that they lack capacity to provide informed consent.
2. Currently taking intracavernosal injection therapy.
3. Severe or complete erectile dysfunction at baseline, defined as an IIEF-5 score ≤7 or self-reported absence of erectile function.
4. Prescribed nitrates or guanylate cyclase stimulators (e.g., riociguat) - pharmacological contraindication to PDE5 inhibitor use.
5. Impaired renal function (GFR \<50 mL/min and/or creatinine clearance \<30 mL/min).
6. Severe hepatic impairment or concurrent prescription of medications that inhibit CYP3A4.
7. Loss of vision in one eye due to non-arteritic anterior ischaemic optic neuropathy (NAION).
8. Myocardial infarction within the last 90 days.
9. Stroke within the last 6 months.
10. Unstable angina or angina occurring during sexual intercourse.
11. New York Heart Association (NYHA) Class II or greater heart failure in the last 6 months.
12. Uncontrolled arrhythmias, hypotension (\<90/50 mmHg), or uncontrolled hypertension.
13. Contraindications to participating in the prescribed exercise program.
14. No access to a device with internet connectivity.
Dates on the record
Results, publications and the official record
- No results are posted on the official record yet.
- No publications are listed on the official record yet.
- Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.
Sources and dates
- ClinicalTrials.gov – the record this page reformats
- ClinicalTrials.gov processing date: 9 September 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Letter for your doctor
A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.