Phase 2 Prostate Cancer Trial, Recruiting NCT05560659 Sponsor: Peter MacCallum Cancer Centre, Australia Condition: Prostate Cancer
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Phase 2 Prostate Cancer Trial, Recruiting

NCT05560659
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Men aged 18 years or older at the time of screening
  • People who have given written consent to participate in the trial
  • People who have been diagnosed with prostate cancer (adenocarcinoma type), confirmed through a tissue sample (biopsy)
  • People who have already had treatment aimed at curing the primary prostate cancer, such as radiotherapy or surgery
  • People who have between 1 and 5 spots of cancer spread (to lymph nodes or bones), detected on a specific type of scan called a PSMA PET/CT
  • People whose blood test results meet certain minimum levels for white blood cells, platelets, haemoglobin, and kidney function (confirm with trial site for specific values)
  • People who a radiation oncologist has assessed as suitable for a targeted radiation treatment called SABR
  • People who agree to use an adequate form of contraception during the trial
  • People with a good general level of physical functioning, rated 0 or 1 on a standard medical scale (meaning fully active or able to carry out light activities)

Who may not be able to join:

  • People who have previously received systemic (whole-body) drug treatment for metastatic prostate cancer; hormone therapy (ADT) used more than 6 months before screening may be allowed, but testosterone levels must have returned to a normal range (confirm with trial site)
  • People whose cancer has spread to internal organs such as the liver or lungs
  • People who have, or are at risk of developing, spinal cord compression due to the cancer
  • People with any other medical condition, ongoing treatment, or abnormal test result that the treating doctor believes would interfere with the trial or would not be in the person's best interest
  • People who have had another active or progressing cancer within the last 2 years — though certain low-risk skin cancers, superficial bladder cancer, or early-stage cancers that have been successfully treated are generally not excluded (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: A/Prof. Shankar Siva, Peter MacCallum Cancer Centre, Australia

Phone: +61 3 8559 6830

Australian sites

Royal North Shore, St Leonards, New South Wales
Peter MacCallum Cancer Centre, Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Peter MacCallum Cancer Centre, Australia
Registry
ClinicalTrials.gov
Start date
14 December 2023
Est. completion
1 May 2026

Where this trial is recruiting

🇦🇺 Australia 🇮🇱 Israel

2 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Evaluate the (bPFS) of SABR alone and SABR + 177Lu-PSMA

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov