Breast Cancer

You have been diagnosed with breast cancer that has not spread to other parts of the body, and the cancer has been confirmed by a tissue sample (biopsy). Your breast cancer is either "triple negative" (meaning it does not respond to certain hormone or targeted therapies) or hormone receptor-positive but HER2-negative…

You have been diagnosed with a type of breast cancer that is hormone receptor-positive (HR+) and HER2-negative (HER2-) Your breast cancer has either come back in the local area and cannot be fully removed by surgery or treated with curative radiation, or it has spread to other parts of the body (metastatic) You have…

You have been diagnosed with breast cancer that is hormone receptor-positive (HR+) and HER2-negative Your cancer has spread to other parts of the body or is advanced in a way that cannot be cured with current treatments Your cancer got worse while you were taking hormone-blocking therapy (such as an aromatase…

You have been diagnosed with stage I, II, or III breast cancer, confirmed by a tissue sample (biopsy) Your cancer is contained within the breast and nearby lymph nodes, with no spread to other parts of the body You have had either a full breast removal (mastectomy) or a breast-conserving surgery (such as a…

You must have previously been treated with chemotherapy drugs from two specific groups: one called an anthracycline (such as doxorubicin or epirubicin) and one called a taxane (such as paclitaxel or docetaxel). You must have had no more than two previous chemotherapy treatment courses in total. If you have not yet…

You have been diagnosed with advanced or late-stage breast cancer (Stage IIIB, IIIC, or IV) that tests positive for a protein called HER2 (also written as erbB2) You have previously been treated with a drug called Herceptin (trastuzumab) and a type of chemotherapy called a taxane Your heart and kidneys are working…

You are a woman aged 18 or older with a confirmed diagnosis of breast cancer that has too much of a protein called HER2 (which helps cancer cells grow) Your breast cancer has either spread to nearby areas or to other parts of the body Your cancer can be measured and tracked using standard imaging methods, according to…

You are a woman with advanced breast cancer (either spread to other parts of the body, or returned in the local area) that cannot be cured. You have gone through menopause — either naturally (based on age or periods stopping for 12+ months), or because you had both ovaries surgically removed. You have not yet received…

Your breast cancer tumor tests positive for a protein called HER2 (confirmed by lab testing of the tumor). You have been diagnosed with breast cancer that has spread to other parts of the body (metastatic), confirmed by a tissue or cell sample, with at least one area that can be measured or tracked. You are well…

You are female and have gone through menopause You have been diagnosed with invasive breast cancer, confirmed by a tissue sample (biopsy) Your tumor is at least 2 centimeters in size, measured by MRI scan Your cancer is classified as Stage I to operable Stage III (meaning it has not spread too far and surgery is…

You have cancer that has spread to the brain (brain metastases) from hormone receptor positive breast cancer, non-small cell lung cancer (NSCLC), or melanoma. If joining Part A, you have HER2-positive breast cancer; if joining Part B, you have HER2-negative breast cancer. If joining Part C, you have hormone receptor…

If you are female, you must be postmenopausal. Your cancer must have been tested to determine the status of a gene called PIK3CA. You relapsed (cancer came back) with clear evidence it was growing while on, or within 12 months of finishing, hormone therapy given before/after surgery, and you have not yet had treatment…

You have been diagnosed with breast cancer that is both HR+ (hormone receptor-positive) and HER2+ (HER2-positive). Your breast cancer cannot be removed by surgery, has come back locally, or has spread to other parts of the body (metastatic). You have enough tumor tissue available for testing before joining the trial.…

You have been newly diagnosed with breast cancer in one breast that has not yet been treated, is confirmed by biopsy to be ER-positive and HER2-negative, and the tumor is at least 2 cm in size. Your doctors have decided that hormone-blocking therapy (without chemotherapy) given before surgery is a suitable treatment…

The person must be female. The person must be between 45 and 75 years old at the time of enrolling in the study. The person must have been diagnosed with stage 1, 2, or 3 breast cancer between 5 and 10 years before enrolling in the study. The person must have received certain types of chemotherapy or radiation…

People who are 18 years of age or older People who have a confirmed diagnosis of breast cancer at stage I, II, or IIIa People who have also been diagnosed with a heart or blood vessel condition, such as heart failure, high blood pressure, coronary artery disease, stroke, a mini-stroke (transient ischemic attack)…

The person has signed a written consent form specific to this trial (called the FERTILE Patient Information and Consent form). The person has been diagnosed with early-stage triple-negative breast cancer (TNBC), as determined by their treating doctor. The person is female and between 18 and 42 years of age. The person…

Adults aged 18 or older, or teenagers aged 12–17 if a Safety Review Committee has given approval for that age group. People who have a solid tumour (cancer that forms a mass) that has spread locally or to other parts of the body, and whose tumour has a specific genetic change called a TP53 Y220C mutation. People whose…

People who have a general health status rated as fully active or able to carry out light work (ECOG score of 0 or 1) People whose breast cancer tests positive for estrogen receptors (ER+) People for whom hormone-based treatment is recommended and chemotherapy is not recommended at the time of joining, based on…

You are 18 years of age or older You are fairly active and able to care for yourself, with little or no limitation on daily activities (this is measured by a standard scale called ECOG, scored 0 or 1) You are willing and able to sign a consent form and follow all study requirements Your cancer has been confirmed by a…

You are scheduled to receive radiation therapy for cancer of the brain, breast, head and neck, kidney, liver, pancreas, prostate, or spine — or for a heart rhythm condition — at a participating treatment centre. You will have a CT planning scan and at least one cone beam CT scan (a type of imaging done during…

People who are in good general health and able to carry out daily activities with little or no limitation (as measured by a standard medical scale called ECOG, with a score of 0 or 1). People who have one or more specific gene changes (mutations) in a gene called PIK3CA, found in a blood or tumour sample. People who…

Women aged 50 or older who have a single breast cancer tumour (in one location only), confirmed by mammogram, ultrasound, and MRI. People whose general health and ability to carry out daily activities meets a certain minimum level (confirm with trial site). People whose tumour size has been measured using MRI. People…

Women who have been newly diagnosed with invasive breast cancer (confirmed by tissue testing) with no sign that the cancer has spread to other parts of the body Women who have had breast-conserving surgery (surgery that removes the tumour but keeps most of the breast) where the edges of the removed tissue are clear of…

You are a male or female aged 18 or older You are willing and able to follow all study requirements throughout the trial Your breast cancer has been confirmed by a lab test (biopsy or cell sample) and is advanced or has spread to other parts of the body Your breast cancer is ER-positive (hormone receptor-positive) and…

People who are over 18 years of age People who have had a breast cancer return in the same breast, or a new breast cancer forming (either a non-invasive type called DCIS or an invasive cancer) People whose tumour measured less than 3.0 cm across at its widest point when examined after removal, including all parts of…

Adults over 18 years old who have triple-negative breast cancer (a specific type of breast cancer that tests negative for three particular markers) and still had cancer remaining in the breast or lymph nodes after completing pre-surgery treatment (chemotherapy given before surgery) People whose surgeon was able to…

People who have given written, dated, and signed consent before any study procedures begin. People with a confirmed diagnosis of certain advanced or spread cancers that cannot be removed by surgery, depending on which part of the trial they are entering (see below). For kidney cancer (clear cell type): people who have…

You are a man or woman aged 18 or older at the time of screening (or meet the age requirement based on your country's guidelines) You have been diagnosed with a specific type of early-stage breast cancer (ER-positive, HER2-negative) that has been confirmed by a tissue sample, and your doctors have assessed it as…

Adults aged 18 or older at the time of signing the consent form People who have been confirmed, through a tissue sample tested by a local lab, to have breast cancer that is estrogen-receptor positive and/or progesterone receptor positive People whose breast cancer has tested negative for HER2 (a specific protein)…

People who are willing and able to sign and date the trial's consent form. People who agree to provide a tissue sample (either a new biopsy or one taken previously) from their cancer. People who have been diagnosed with breast cancer that cannot be surgically removed and/or has spread to other parts of the body.…

People who are able to understand the study and are willing to sign a written consent form before any study procedures begin People aged 18 years or older People who have a confirmed solid tumour or lymphoma that is advanced, cannot be surgically removed, or has come back and is getting worse since their last cancer…

You have breast cancer that has spread locally or to other parts of the body, and it cannot be cured with current treatments Your tumor has tested positive for estrogen receptors (ER+) and negative for a protein called HER2 (HER2−), based on a recent or archived tissue sample You have had a blood test (through the…

People who have been diagnosed with triple-negative breast cancer (TNBC) that has either spread to other parts of the body or come back in a way that cannot be treated with surgery or with the aim of curing it. People who are generally well enough to carry out daily activities with little or no limitation (based on a…

People aged 18 or older who are willing and able to sign a consent form before any study procedures begin People with skin (cutaneous) melanoma — including acral (affecting palms or soles) or non-acral types — that has been confirmed by laboratory testing, and whose disease has continued to grow or spread after at…

Adults aged 18 or older who are able to give informed consent People whose general health and blood test results meet the required standards set by the trial People who have a stored tumour tissue sample available, or who are able to have a fresh tumour biopsy taken; people for whom a fresh biopsy is not safely…

People who have been diagnosed with a solid tumour cancer, confirmed through a tissue or cell sample. People who are 18 years of age or older. People who have at least one tumour measuring 1 cm or more visible on a recent PET/CT scan (a type of imaging scan). A small number of participants may be enrolled even if…

Adults of any gender, including women who are pre-menopausal, peri-menopausal, or post-menopausal People with a confirmed diagnosis of hormone receptor-positive, HER2-negative breast cancer (confirmed through a tissue or cell sample) People whose breast cancer is either advanced and cannot be cured with local…

People who have been confirmed (by a central laboratory) to have triple-negative breast cancer (TNBC), as defined by the latest standard medical guidelines People who show no signs of the cancer returning or spreading, as assessed by their treating doctor People who received a specific pre-surgery chemotherapy and…

People who have one of the following solid tumour cancers, depending on the group (cohort) they would be placed in: urothelial carcinoma, triple negative breast cancer, non-small cell lung cancer, esophageal cancer, pancreatic cancer, ovarian cancer, cervical cancer, head and neck squamous cell carcinoma, or prostate…

People who previously took part in the MNPR-101-D001 study. Women who could become pregnant must have a negative pregnancy blood test at the screening visit, and a negative pregnancy urine test on the first day of treatment if screening took place more than 7 days earlier. Both men and women must agree to use highly…

You have been confirmed (through a biopsy or cell sample) to have breast cancer that is hormone receptor-positive (HR+), HER2-negative, and has either spread to other parts of the body or cannot be surgically removed. You are an adult woman (before or after menopause) or an adult man. Women who have not yet gone…

People who have triple-negative breast cancer (TNBC) that has come back or spread and cannot be removed by surgery or cured People who have not yet received any systemic (whole-body) treatment for their breast cancer that has come back or spread People who were previously treated for early-stage breast cancer must…

Adults aged 18 or older. People with advanced solid tumour cancers that have been confirmed by laboratory testing of tissue or cell samples, where the cancer has continued to grow despite standard treatment, or where no standard treatment exists. People who are largely able to carry out daily activities with little or…

People who have been diagnosed with high-risk, early-stage breast cancer that has not spread to other parts of the body (non-metastatic), and whose tumor and lymph node involvement falls within specific size and spread categories as assessed by their doctor using scans or physical examination People whose breast…

People who are in good general health and able to carry out daily activities with little or no limitation (measured by a standard scale called ECOG, with a score of 0 or 1). People whose cancer has one or more specific gene mutations in a gene called PIK3CA, which are known to drive cancer growth. Adult women (whether…

You have been diagnosed with a type of breast cancer that is hormone receptor positive (HR+) and HER2 negative, and the cancer has either spread to other parts of the body or is locally advanced and cannot be completely removed by surgery Your cancer has been tested and confirmed through a biopsy (a tissue sample…

You have been diagnosed with breast cancer that is HR-positive and HER2-negative, and the cancer has spread locally or to other parts of the body and cannot be removed by surgery or treated with radiation to cure it. You have previously been treated with a type of drug called a CDK4/6 inhibitor (such as palbociclib…

Adults of any gender are welcome to participate. You have been diagnosed with breast cancer that is estrogen receptor positive (ER+) and HER2 negative (HER2-), and the cancer has either spread to other parts of the body or cannot be removed with surgery. Your cancer can be measured or tracked through scans, or you…

(Part 1A only) People with advanced or metastatic breast cancer or other solid tumours whose cancer has spread, and who have already tried all available standard treatments, cannot tolerate them, or have no standard treatments left. (Parts 1B and 2A only) People with advanced breast cancer who have received between 1…

People who are able to give written consent and understand what the study involves, including its purpose and potential risks Adults aged 18 or older at the time of screening People with a life expectancy of at least 3 months People whose cancer has been confirmed by laboratory testing (tissue or cell sample) and…

You are able to understand what the trial involves and any possible side effects, and you are willing to take part voluntarily. Your bone marrow and other major organs (such as heart, kidneys, and lungs) are working well enough to meet the trial's requirements. Your liver is functioning at an adequate level based on…

Adults aged 18 or older at the time of giving consent to participate. Women in Cohort A (hormone receptor-positive, HER2-negative breast cancer) must be postmenopausal, meaning they have not had a menstrual period for 12 or more consecutive months without another medical explanation. People in Cohort B (kidney cancer…

You have been diagnosed with breast cancer that has spread or cannot be removed by surgery, and your cancer has been confirmed as HER2-positive by a central laboratory. Your cancer has at least one tumor that can be measured by scans (required for the first part of the trial; the second part may also accept those…

People who are at least 18 years old (or the legal age of consent in the country where the trial is taking place) at the time of signing the consent form. People who have been diagnosed with breast cancer that is hormone receptor positive (HR+) and HER2 negative (HER2-), and where the cancer has either spread to…

Adults aged 18 or older People with a confirmed diagnosis of certain advanced cancers that have continued to grow or spread after standard treatments, and where no other standard treatment with proven benefit is considered appropriate by the treating doctor People with advanced HER2-positive breast cancer that has…

You have been diagnosed with a type of breast cancer called breast adenocarcinoma You have already been treated with two specific types of chemotherapy drugs — an anthracycline and a taxane — either together or one after the other, whether that was before surgery, after surgery, or for advanced disease, with no more…

You are a woman who has gone through menopause, as defined by the trial's specific guidelines Your breast cancer has been confirmed by a lab test and is driven by estrogen and/or progesterone (hormone receptor-positive) A blood test shows you carry at least one of five specific genetic markers related to your immune…

You are scheduled to receive your own previously collected stem cells back (called an autologous stem cell transplant). You speak and understand English. Your stem cell infusion is planned to take place at the SCCA outpatient clinic.

People who have been diagnosed with certain cancers confirmed by laboratory testing, including non-small cell lung cancer, melanoma, bladder or urinary tract cancer, kidney cancer, triple negative breast cancer, uterine cancer, head and neck cancer (Phase 1), or ovarian cancer, bowel cancer with a specific genetic…

People aged 18 years or older. People with HER-2 positive breast cancer (a specific type of breast cancer identified through testing) who are scheduled to receive a drug called trastuzumab, with or without having previously had a type of chemotherapy called anthracycline-based treatment. People with breast cancer that…

Women between the ages of 40 and 74 Enrolled in MyChart (an online health record system) Able to read English

You must have already completed the Week 48 visit (Visit 9) of the TOL2506A study and be considered suitable to continue hormone therapy with ovarian suppression You must be able to understand what this study involves and sign a consent form agreeing to take part You must be between 18 and 51 years old (inclusive) You…

People who have had a total mastectomy (complete surgical removal of the breast). People who have had breast reconstruction using an implant, their own body tissue, or both.

People with a good general health and activity level, scored as 0 or 1 on a standard medical performance scale (called the ECOG scale) People with breast cancer that can be removed with surgery People who, after surgery, have no signs of cancer that has spread to other parts of the body on imaging scans People who are…

People who have a good general level of physical functioning, with little to no limitation in daily activities (based on a standard medical scoring system called ECOG, with a score of 0 or 1). People who have been diagnosed with triple-negative breast cancer (a specific type of breast cancer that lacks three common…

People who have been diagnosed with breast cancer. People who are receiving a radiotherapy dose as part of their treatment.

People who are 18 years of age or older at the time of signing the consent form. People who are able to follow the study plan, as assessed by the trial doctor. People who have a tumour tissue sample available to confirm a HER2-positive diagnosis. People whose cancer has been tested and confirmed as HER2-positive —…

People aged between 20 and 70 years old. People who have been newly diagnosed with breast cancer at stage I, II, or III, with no previous history of cancer. People who are able to read and write, and do not have significant cognitive difficulties. People who are able to write and communicate in Chinese.

You must be 21 years of age or older You must be able to speak English You must be a registered attendee of the advanced 7-day meditation retreat You must be willing to wear a Garmin wearable device for the entire duration of the retreat You must agree to and sign the research consent form to take part in the study…

The person must be female. The person must be at least 18 years old. The person must have been diagnosed with breast cancer that is estrogen-receptor positive (meaning the cancer cells are fuelled by the hormone estrogen). The breast cancer must be a primary tumor, meaning it started in the breast and has not spread…

People who are 18 years of age or older. People who have stage 1, 2, or 3 lymphedema as classified by the International Society of Lymphology (ISL). People who have been diagnosed with lymphedema in one arm related to breast cancer treatment, confirmed through appropriate medical tests (such as Doppler…

People who are 30 years of age or older. People who are able to read and write at a basic level. People who score 301 or higher on the Breast Cancer Risk Assessment Form. People who do not have vision or hearing difficulties that would prevent them from communicating during the study. People who are willing to take…

People who are cisgender women assigned female at birth People who are 18 years of age or older People who have been diagnosed with Stage 1, 2, or 3 hormone receptor-positive breast cancer People who are premenopausal and are receiving a type of medication (GnRH agonist or antagonist) to temporarily stop their ovaries…

Women aged 20 to 70 years old. People with a confirmed diagnosis of invasive breast cancer for whom a sentinel lymph node biopsy has been determined to be an appropriate procedure.

People who are physically well enough to walk and carry out normal daily activities (based on a standard health scoring system called ECOG, scored 0 or 1). People who have been diagnosed with early-stage breast cancer that is HER2-positive and has spread to the lymph nodes under the arm. People whose breast cancer is…

People diagnosed in the past 6 months with one of these cancers at Stage I, II, or III: breast cancer, prostate cancer, urinary bladder cancer, or endometrial cancer People whose cancer treatment has the goal of curing the cancer (rather than just managing it) People who had their first visit at the cancer centre…

People aged 18 years or older. People who have been clinically diagnosed with Cancer of Unknown Primary (CUP) syndrome — a cancer that has been found in the body but where doctors have not yet identified where it originally started. People where doctors suspect, based on physical examination or scans, that the cancer…

Women aged 18 to 70 who have been diagnosed with breast carcinoma in situ (a very early form of breast cancer that has not spread beyond the breast ducts or lobules). The breast tumour measures at least 2cm, and testing has confirmed it is HER2-positive (meaning the cancer cells have high levels of a certain protein…

People who are between 18 and 75 years of age (inclusive). People who are female. People who have been diagnosed with breast cancer confirmed through a laboratory tissue test. People who are expected to have surgery as part of their treatment. People who are expected to live for at least 1 year. People whose bone…

People who are 18 years of age or older. People who have been diagnosed with breast cancer confirmed through laboratory testing of tissue samples. People who have one or more areas where the cancer has spread to other parts of the body, confirmed by tissue testing or medical imaging. People who have previously…

People who have had breast cancer that was diagnosed at stage I, II, or III and have completed treatment. People who speak and understand English fluently. People who live in a neighborhood that has been rated as having a high level of disadvantage or deprivation.

The person must voluntarily sign a consent form agreeing to take part. The person must be 18 years of age or older. The person must have breast cancer that has either been confirmed through a tissue test or is strongly suspected based on standard imaging scans. The person's doctor must estimate that they have a life…

People who are 18 years of age or older. People who have been diagnosed with breast cancer that has spread to nearby lymph nodes and are currently receiving additional radiotherapy treatment after their main treatment. People who are willing to take part in the alginate (a seaweed-based substance) treatment trial.

People with breast cancer whose doctors have identified intraoperative radiation (radiation given during surgery) as the planned treatment approach on its own. People with breast cancer whose doctors have identified intraoperative radiation combined with external beam radiation (radiation given from outside the body…

People who are participating in the Danish breast cancer screening program.

People who had breast cancer surgically removed and then experienced the cancer coming back in the same location. People whose tumours (both the original and the returned cancer) have been tested for three specific markers known as ER, PR, and HER2/neu.

Women who are 18 years of age or older and living in the middle region of Syria.

People who are 19 years of age or older. People who are scheduled to have a specific type of breast reconstruction surgery (called a DIEP flap) after having a mastectomy for breast cancer or to reduce the risk of breast cancer. People who are already scheduled to have a pre-surgery scan called a CTA as part of their…

People who are older than 19 years of age. People who have been diagnosed with breast cancer (confirmed through a tissue sample) that has spread to other parts of the body or has advanced locally in a way that cannot be treated with surgery, with or without measurable tumours. People whose breast cancer was already at…

Women who have been diagnosed with breast cancer that has not spread to other parts of the body (confirmed by a tissue test), and who are currently receiving one of the following treatments: chemotherapy before surgery (which may also include immunotherapy or anti-HER2 therapy), chemotherapy after surgery (which may…

People with breast cancer who are between 18 and 80 years old and have nerve damage caused by chemotherapy (a condition called CIPN). People who have previously received chemotherapy that included a type of drug known as taxane, which can damage nerves. People experiencing nerve-related pain that rates 3 or higher on…

Women aged 18 or older who have one or more large calcium deposits (macrocalcifications) found in a standard 2D or 3D mammogram. Women aged 18 or older who have one or more large calcium deposits located near a cyst or other clearly identifiable feature visible on an ultrasound image. Women aged 18 or older who have a…

People with advanced or metastatic solid tumours that cannot be cured, where standard treatments have stopped working, are not tolerated, or where a doctor has determined the person is not suitable for standard treatment (or the person has chosen not to have it). Eligible cancer types include relapsed or…

People who are older than 18 years of age. People who have had previous testing on their primary tumour to check for estrogen receptor status (a type of hormone receptor test), and those results are available. People whose blood counts and organ function fall within the required ranges — specifically: white blood cell…

Participants must be Singaporean citizens. Participants must be between 50 and 69 years of age. Participants must be registered as a patient at the National University Hospital. Participants must be registered and active users of the NUHS App. Participants must be signed up with Healthier SG with a primary care…

People who are scheduled for breast cancer surgery and have not received any treatment for the cancer before the operation.

Adults aged 18 years or older. People with a laboratory-confirmed diagnosis of triple-negative breast cancer (TNBC) that has come back or spread to other parts of the body. People whose cancer has been tested and meets specific definitions of being "triple-negative" (low levels of estrogen and progesterone receptors…

Female patients who were diagnosed with breast cancer at age 40 or younger. People with breast cancer that has been confirmed through laboratory testing (such as a biopsy), where the cancer is at stage 0, I, II, or III, and the disease is either stable or progressing. People who have complete medical records and…

Women aged 18 or older, whether or not they have gone through menopause. People who have been diagnosed with a specific type of breast cancer that is hormone receptor-positive and HER2-negative (HR+/HER2-). People who are currently receiving, or are planned to receive, a type of cancer treatment called a CDK4/6…

People who are female and aged 18 years or older People who are having a mastectomy, either to treat breast cancer or as a preventive measure People who are having immediate breast reconstruction using an implant, either on its own or combined with the person's own tissue

People between 18 and 75 years old. People who have a confirmed breast cancer diagnosis at stages IB through IIIC. People who are scheduled to receive chemotherapy before surgery (called neoadjuvant chemotherapy) as part of their treatment plan. People who show an acceptable level of baseline memory and thinking…

Women between 18 and 75 years of age. People who have been confirmed through a tissue sample (biopsy) to have invasive breast cancer that has spread to the lungs, diagnosed using specialised scans such as a CT, PET-CT, or MRI. People whose cancer has continued to grow or spread after receiving at least one course of…

Women between the ages of 25 and 75 years old. People who have been diagnosed with breast cancer confirmed through a laboratory tissue test. People who are currently receiving chemotherapy after having surgery for breast cancer. People whose general health and ability to carry out daily activities falls within a…

People who are adults aged 18 or older People who are a licensed healthcare professional, such as a medical doctor (MD or DO), licensed psychologist (PhD or PsyD), advanced practice provider (ARNP or PA), nurse (RN or LPN), licensed clinical social worker (LCSW), or another type of licensed clinician People who…

People who are Singaporean citizens People aged between 50 and 69 years old People who are registered as a patient at the National University Hospital People who are registered and active users of the NUHS App People who have signed up with Healthier SG and have a primary care provider within the NUHS Primary Care…

Women between 18 and 70 years old People who have completed surgery to fully remove the tumour (radical surgery) People whose breast cancer has been confirmed by laboratory testing as a specific type called invasive ductal carcinoma People whose tumour was smaller than 8mm, had not spread to the lymph nodes, and…

People who have a solid tumour that tests positive for a specific protein marker (either strongly positive on an immunohistochemistry test, or showing gene amplification on a FISH test). People who are at least 18 years old. People who are able to give their informed consent to take part. People who have a Karnofsky…

Women aged over 18. People with breast cancer that has been confirmed as HER2-positive through laboratory testing (either a strong positive result on one test, or a moderate result confirmed by a second test). People whose breast cancer has been confirmed by tissue or cell testing and has either come back in the same…

A treating doctor has decided, based on Korean prescribing guidelines, that the person is due to start treatment with Talzenna® (talazoparib). The person (or their legal representative) has signed and dated a consent form, showing they have been fully informed about all aspects of the study.

Women aged 18 or older. People who have agreed to planned breast reconstruction surgery using a tissue flap taken from the abdomen (called a DIEP flap), either at the same time as a mastectomy or at a later date.

Participants must be over 18 years of age. The breast tumor must have been confirmed as invasive cancer through a core biopsy (a tissue sample taken with a needle). The tumor must meet one of these size or stage conditions: shrinkage of the tumor is needed to make complete surgical removal possible; or shrinkage is…

Women between the ages of 19 and 40 years old People who have been diagnosed with breast cancer confirmed by a biopsy People who have no signs that the cancer has spread to distant parts of the body People with a general health and activity level score of 0 to 2 on a standard scale used by doctors to measure how well…

Women who have had a mastectomy (full breast removal) for invasive breast cancer. People who have had breast reconstruction surgery after mastectomy, or who have had a tissue expander inserted. People whose cancer was classified as stage IIIA or lower after surgery (excluding certain tumour and lymph node…

People who are older than 18 years of age. People who have been diagnosed with stage I to stage IV breast cancer and have not yet started any main treatment for it. People who are having routine screening mammograms to check for breast cancer.

People aged between 18 and 75 years old. People who have been taking hormone therapy (such as tamoxifen and/or aromatase inhibitors), with or without treatment to suppress ovarian function, for at least 4 weeks and are still currently on that treatment. People who have been experiencing vasomotor symptoms (such as hot…

Adults (men or women) aged 18 or older. People who have been diagnosed with advanced breast cancer (either spread to other parts of the body, or locally advanced), confirmed by a tissue sample. People whose tumor does not have high levels of a protein called HER2, as confirmed by specific lab tests on the tumor…

People who are female People who have been diagnosed with Stage I or Stage II cancer People between the ages of 18 and 90 years old People diagnosed with invasive carcinoma that is triple negative (meaning the cancer tests negative for estrogen receptors, progesterone receptors, and HER2) People whose cancer appears…

Women who have been diagnosed with triple-negative breast cancer (TNBC), confirmed by a biopsy, who are not planned to receive chemotherapy before surgery. People whose breast tumor is 2 cm or smaller and has not spread to lymph nodes. People who are planned to have surgery first, based on their own preference. People…

Women between 18 and 70 years of age. People with a confirmed diagnosis of primary invasive breast cancer (a specific type called adenocarcinoma) where medical guidelines recommend chemotherapy either before or after surgery. People who have not had any other cancer or received any other chemotherapy. People who have…

Women between 18 and 70 years of age. People diagnosed with a single breast cancer (not both breasts) that has not spread to distant parts of the body, where the tumour measures at least 1 cm. People whose breast cancer test results show: hormone receptors (ER and PR) are less than 10% positive, AND HER-2 results fall…

People aged between 18 and 75 years old, of any gender. People who have been diagnosed with breast cancer confirmed by pathology (tissue analysis) after surgery. People whose imaging scans and pathology tests show no signs of the cancer coming back or spreading. People with raised tumour markers who have already been…

People who are willing to take part and sign a consent form agreeing to join the study. People aged 18 years or older. People who have breast cancer that has spread or cannot be removed by surgery, confirmed by laboratory testing of tissue or cells. People whose cancer has tested HER2-positive through a central…

People who have been diagnosed by a pathologist (lab tissue testing) with breast cancer that has come back in the same area or spread to other parts of the body, and whose cancer is hormone-receptor positive and HER2 negative. People aged between 18 and 75 years old. People who are either fully active or have only…

Adults aged 18 to 75 years old. People diagnosed with HER2-positive invasive breast cancer confirmed by laboratory testing, where HER2 is strongly positive on tissue staining (IHC 3+) and/or confirmed by a gene test called FISH. People whose breast cancer is either locally advanced and cannot be operated on, or has…

Women aged 18 to 70 who have not yet started treatment for breast cancer. People newly diagnosed with high-risk early-stage or locally advanced breast cancer (stage II or III), covering several breast cancer types: triple negative breast cancer (TNBC), HER2-positive breast cancer, hormone receptor (HR)-negative HER2…

People who are able to voluntarily sign a consent form agreeing to take part in the study. Women aged 18 or older at the time of signing the consent form. People with a general health and activity level rated between 0 and 2 on a standard medical scale (meaning able to carry out at least some daily activities…

Women aged 18 or older at the time of signing the consent forms. People who have been confirmed through laboratory testing (from tissue or cell samples) to have breast adenocarcinoma (a type of breast cancer). Women with breast cancer that has either spread to other parts of the body, cannot be treated with surgery or…

People aged 21 years or older. People with a confirmed diagnosis of HER2-positive cancer, based on laboratory testing of tumour tissue (specific testing methods are used to confirm HER2 status). For the first phase of the trial: people with HER2-positive breast cancer, stomach (gastric) cancer, or other HER2-positive…

People who are able to receive chemotherapy treatment given throughout the body (systemic chemotherapy). People who had cancer that had spread to nearby lymph nodes when first diagnosed (this is what "cN1 at presentation" means — confirm with trial site). People whose lymph node involvement was confirmed by a tissue…

Women aged 18 or older Women who have been diagnosed with breast cancer and have not yet started any cancer treatment Women who are willing to read and sign a consent form agreeing to take part in the study

People who have had a breast biopsy sample processed at the pathology laboratory at St James's University Hospital (SJUH), Leeds Teaching Hospitals NHS Trust (LTHT).

People diagnosed with inflammatory breast cancer. People whose cancer showed a complete response to chemotherapy given before surgery (meaning the cancer appeared to disappear based on clinical assessment). People with a clearly identified, targeted tumour. People who have provided written consent to participate in…

People with a confirmed diagnosis of breast cancer (stage I to IV) that has not yet been treated with any first-line therapy and is planned to be treated with chemotherapy before surgery, or chemotherapy combined with radiation therapy before surgery. The cancer must be measurable by ultrasound or MRI, with that scan…

People who have recently been diagnosed with breast cancer at any stage and are being admitted to the South Egypt Cancer Institute.

People aged between 18 and 75 years. People with a confirmed diagnosis of primary triple negative breast cancer (a specific type of breast cancer identified through lab testing of tissue). People who have already received treatment such as chemotherapy, radiotherapy, or surgery, and whose tumour has been found in…

People who are able to understand the study and sign a written consent form before any study procedures begin. People who are aged between 18 and 75 years old (inclusive) at the time of signing the consent form, of any gender. People who have a physical fitness score of 0 or 1 on the ECOG scale, which means they are…

Women aged 18 or older who have signed a consent form and are expected to live for at least 3 more months. People whose general physical health and ability to carry out daily activities meets a certain level, as measured by a standard medical scoring system, within 21 days before the first dose (confirm with trial…

People aged between 18 and 65 years old People who have recently been diagnosed with breast cancer that has been confirmed by a tissue sample and surgically removed, at an early to intermediate stage (Stage I to IIIa) People who are scheduled to receive a specific chemotherapy combination involving two drugs called…

People who have given informed consent before any study-related procedures take place. People aged 18 years or older. People with a pathology-confirmed diagnosis of advanced or metastatic breast cancer that has tested HER2-positive (IHC3+ or ISH+) on examination of either the primary or metastatic tumour at the trial…

People aged 20 years or older. People who do not have cancer that has spread to distant parts of the body, based on clinical assessment or imaging. People whose breast cancer type is either invasive ductal carcinoma or invasive lobular carcinoma. People whose breast cancer subtype is triple negative (meaning the…

Adults aged 18 or older at the time of signing the consent form. People who have at least a basic understanding of French. People who have signed the study consent form before any study-related procedures begin. People who are taking part in the RESTART programme. People diagnosed with breast cancer that is being…

People who have given written informed consent to participate. Women aged 18 years or older. People who have a good general physical functioning level, rated 0 or 1 on a standard oncology fitness scale (confirm with trial site). People with a life expectancy of more than six months. People diagnosed with HER2-negative…

People diagnosed with invasive breast cancer of the ductal type, or a mixed ductal and lobular type.

People with breast cancer that has been confirmed by lab testing to be HER-2 negative and hormone receptor (HR) positive, and whose cancer has continued to grow or spread, and who have previously received chemotherapy containing anthracycline and/or paclitaxel (either before or after surgery, or for advanced disease).…

People with previously untreated primary breast cancer that has spread to the lymph nodes above the collarbone (supraclavicular lymph nodes), or people who developed this spread within 5 years after completing treatment, with no other spread elsewhere — meeting specific staging criteria defined in international…

People who are willing to take part voluntarily and sign a consent form. Women aged 18 to 70 years old who have been newly diagnosed with breast cancer confirmed by tissue testing as ER-positive and HER2-negative, with a histological grade of II, a Ki-67 score of 20% or higher, and a specific stage of cancer spread…

The person must be female. The person must be 18 years of age or older. The person must have been diagnosed with triple-negative breast cancer (a specific type of breast cancer defined by low levels of certain receptors), confirmed through a tissue sample, and must not have received any previous treatment for it. The…

People who are starting (neo)adjuvant chemotherapy for breast cancer under one of the following specific treatment plans: four cycles of doxorubicin and cyclophosphamide given every two weeks, followed by twelve weekly doses of paclitaxel (sometimes combined with carboplatin); or nine cycles of paclitaxel…

People who have been diagnosed with metastatic breast cancer confirmed through tissue or cell testing. People who have evidence of cancer that has spread, confirmed by imaging scans (such as CT, MRI, or PET) and/or biopsy. People who have already completed at least one round of systemic treatment (such as…

Women aged 18 to 80 years old who have been diagnosed with early breast cancer confirmed by a laboratory tissue test. People who have not yet received any cancer treatment and are planning to start chemotherapy before surgery (called neoadjuvant chemotherapy). People who have mild anxiety, as measured by a score of 50…

Women between 18 and 75 years of age. People being referred for the first time to the breast clinic or inpatient department of the study centre because a previous procedure, within the last 30 days, found suspicious changes in the breast. People whose breast MRI scan before surgery showed a main area of concern rated…

People aged 18 or older. People whose general health and ability to carry out daily activities meets a certain standard (known as ECOG performance status of 2 or below — confirm with trial site if unsure what this means for a specific situation). People who have been diagnosed with HER2-positive breast cancer (a…

Women who are first-time breast cancer patients aged 18 or older. People whose breast cancer has been confirmed by tissue examination (pathology) to be HER2-positive, meaning the cancer tests strongly positive on a specific protein test (IHC 3+), or moderately positive (IHC 2+) with gene amplification confirmed by a…

People aged 18 years or older. People who have been confirmed through tissue or laboratory testing to have HER2-positive breast cancer that has either spread to other parts of the body or cannot be removed with surgery (HER2-positive means a specific test called IHC showed a score of 3+, or a test called ISH came back…

A person has been diagnosed with triple-negative breast cancer (TNBC), confirmed by a tissue biopsy, and the tumour can be measured by ultrasound. The cancer is at a specific stage — either a tumour sized T1c with some lymph node involvement (N1–2), or a tumour sized T2–4 with or without lymph node involvement (N0–2).…

People who are 18 years of age or older. People who have been diagnosed with breast cancer confirmed through a laboratory or tissue test. People whose breast cancer is locally advanced (meaning the cancer has grown larger or spread to nearby tissue or lymph nodes, but has not spread to distant parts of the body).

People who have recently been diagnosed with stage I, II, or III breast cancer People whose treatment plan includes therapies that can affect the heart, such as certain chemotherapy drugs (anthracyclines), targeted therapies, or radiotherapy People who have signed a form giving their informed consent to take part…

The person has voluntarily agreed to take part, signed a consent form, and is willing and able to follow the study procedures. The person is a woman aged 18 to 70 years old (age calculated on the day the consent form is signed). The person has been diagnosed with breast cancer that cannot be surgically removed, has…

Women aged 18 to 75 years who are being treated for breast cancer for the first time. The cancer has been confirmed through lab testing to be HER2-positive (a specific protein that affects how cancer cells grow). The breast cancer has been confirmed through tissue biopsy and imaging scans as either early-stage or…

People aged 18 to 75 years old. People whose general health and ability to carry out daily activities is rated at a good level (score of 0 or 1 on a standard oncology scale). People expected to live for at least 12 weeks. People who have at least one measurable tumour lesion, based on standard imaging measurement…

The person has breast cancer that has been confirmed by a pathology test, cannot be removed by surgery, or has spread to other parts of the body. The cancer has a low level of a protein called HER2, measured at specific levels (IHC 2+/ISH- or IHC 1+) on testing. The cancer is hormone receptor-positive (meaning it is…

Women aged 18 or older at the time of being assigned to a treatment group. People diagnosed with invasive breast cancer that has not yet been treated, where the cancer tests positive for HER2 (a protein found on some cancer cells), confirmed by local laboratory testing according to standard guidelines within the past…

People who are willing to take part voluntarily and sign a consent form. People aged 18 years or older. People with a general health and activity level rated between 0 and 2 on a standard medical scale (ECOG performance status), meaning they are fully active to capable of limited self-care (confirm with trial site).…

Women aged 18 to 70 years. People with a laboratory-confirmed diagnosis of a specific type of breast cancer that is hormone receptor (HR)-positive and HER2-negative, which is either locally advanced (meaning surgery or other local treatment is not possible) or has spread to other parts of the body, and whose cancer…

People who are willing to take part in the study and are likely to follow the study requirements. People aged between 18 and 75 years old, with a general health and activity level rated as 0 or 1 on a standard medical scale (meaning they are fully active or have only minor limitations in physical activity). People who…

People aged 18 to 75 years old (both ages included), of any sex. People with breast cancer that cannot be surgically removed, or that has come back, or that has spread to other parts of the body. People whose tumour tissue has tested positive for HER2 (a specific protein), based on specific lab test results (IHC3+ or…

Women between the ages of 20 and 60 who have not received chemotherapy or surgery for any condition, falling into one of three groups: healthy volunteers with no breast problems, people with non-cancerous breast lumps or growths, or people diagnosed with breast cancer.

Women who are postmenopausal — either through surgical removal of both ovaries, being aged 60 or older, or (if under 60) having had no natural menstrual period for at least 12 consecutive months, with hormone test results confirming postmenopausal levels. People whose breast cancer has tested positive for estrogen…

People who have been diagnosed with breast cancer that has been confirmed by tissue testing and fully removed by surgery. People who are menopausal, either naturally or as a result of medical treatment. People who have no signs of cancer that has spread to other parts of the body. People who identify as having…

Women who are premenopausal or postmenopausal — postmenopausal status is defined as having had both ovaries removed, being aged 60 or older, or being under 60 with periods stopped naturally for at least 12 consecutive months and hormone levels confirmed at postmenopausal levels. People diagnosed with invasive breast…

People aged 18 years or older. People diagnosed with an invasive form of breast cancer that is oestrogen receptor positive (ER+). People who are not currently on any treatment for diabetes. People who are planned to start a type of hormone-based treatment after their main breast cancer treatment (called adjuvant…

People who are female and having a surgery called a unilateral Modified Radical Mastectomy (removal of one breast and nearby lymph nodes). People rated as ASA Grade I or II, meaning they are generally healthy or have only mild health conditions (confirm with trial site). People between 35 and 60 years of age.

People aged 18 to 75 years old (both ages included), of any sex. People with breast cancer that cannot be surgically removed, has come back, or has spread to other parts of the body. People who have previously received no more than two rounds of chemotherapy (not counting hormone therapy) for breast cancer that has…

People aged 60 or older who have invasive breast cancer (of a certain size range) with no cancer spread to the lymph nodes under the arm, who had breast-conserving surgery (such as a lumpectomy), received a high-risk result on a Mammaprint or Oncotype tumour gene test, and are receiving chemotherapy. (If no lymph node…

Women aged 18 or older People who have been confirmed through a tissue sample (before surgery) to have invasive breast cancer or a type of early-stage breast cancer called ductal carcinoma in situ People whose tumour is classified as a smaller size, with the largest measurement being no more than 5 cm People with a…

People who have given signed written consent before enrolling People aged 18 years or older People with a good general health and activity level (ECOG performance score of 0 or 1, meaning fully active or able to carry out light work) People newly diagnosed with a specific stage of breast cancer (T1c N1-2 or T2-3 N0-2…

Women aged 18 to 75 who are postmenopausal (including those who have had both ovaries removed, are 60 or older, or are under 60 with confirmed postmenopausal hormone levels) or who are pre- or perimenopausal and willing to receive hormone-suppressing injections (LHRH agonist therapy) during the study. People with…

People who are 18 years of age or older. People who have given their informed consent to take part in the trial. People who fall within a certain range of general health status, classified as Category 1, 2, or 3 by an anaesthesiologist (confirm with trial site for what this means in individual cases). People who are…

Women aged 18 to 75 years who have newly diagnosed breast cancer that is currently being treated. The breast cancer has been confirmed by laboratory testing to be HER2 positive (a specific protein found on cancer cells, confirmed by certain test results). The breast cancer has been confirmed by tissue biopsy and…

People who are over 18 years of age. People who have a confirmed breast cancer diagnosis proven through a tissue sample (biopsy). People who have documented evidence of bone metastases (cancer that has spread to the bones) shown on a CT scan or MRI scan. People who have been monitored and followed up by their medical…

People who have been diagnosed with hormone receptor-positive (HR-positive) invasive breast cancer.

Adults between 18 and 70 years old (inclusive). People with a performance status score of 0, 1, or 2 on a standard scale used by doctors to measure how much a person's cancer affects their daily activities (ECOG scale). People who have triple-negative breast cancer (TNBC) that has spread to other parts of the body or…

Women between the ages of 18 and 75. People who are scheduled for planned (non-emergency) breast cancer surgery, either full breast removal or surgery that removes only part of the breast. People who have been assessed as generally healthy or having only mild systemic illness based on a standard pre-surgery health…

The person must be female. The person must be 21 years old or older. The person must have a confirmed diagnosis of breast cancer at any stage, either through a tissue sample (biopsy) or through agreement by a specialist medical team, for example when a biopsy is not possible due to the cancer having spread. The person…

Women between 18 and 75 years old at the time of signing the consent form. People with breast cancer that has spread, come back, or cannot be removed by surgery, where the cancer is confirmed by tissue testing to be ER-positive and HER2-negative. People who have previously received at least one hormone-based treatment…

Adults aged 18 years or older. People with breast cancer (during certain parts of the trial, other cancer types may also be considered — confirm with trial site). People who are able to provide a tumor tissue sample that tests positive for a protein called EGFR, as confirmed by the trial's central laboratory. People…

Women between 18 and 75 years of age. People whose breast cancer has been confirmed through laboratory tissue testing and protein marker testing. People who have not received any anti-cancer medicines before surgery. People whose liver and kidney function test results fall within acceptable ranges when checked within…

Patients must fit into one of three groups (cohorts) described below. Cohort 1: People who previously took part in the TAILORx study, received a recurrence score (a lab test result) anywhere between 0 and 100, and have since had a biopsy confirming that their cancer came back — either in the same area, in a distant…

People who are able to understand, agree to, and sign a consent form before any trial-related procedures take place, and who are willing to follow the trial schedule and procedures. People who are covered by a social security or health insurance system. People who are 18 years of age or older at the time of joining…

People aged 18 or older, of any gender. People who have been confirmed through laboratory testing to have Stage I breast cancer, where the invasive tumour measures no more than 2 cm and cancer has not spread to the lymph nodes. People who have been confirmed through tissue testing to have triple-negative breast cancer…

People who are suspected of having breast cancer.

People who have already finished a specific type of radiotherapy treatment for left-sided breast cancer, which involved holding a deep breath during the sessions (known as DIBH-IMRT).

People who are over 18 years old. People who have been diagnosed with metastatic triple-negative breast cancer (mTNBC), meaning their breast cancer has spread and has tested negative for three specific markers (ER, PgR, and HER2), as confirmed by lab testing of tumour tissue. People whose cancer spreading to other…

People aged between 18 and 70 years old People who have been diagnosed with cancer of the digestive system, breast, gynaecological organs, head and neck (ENT), or lungs People who have been receiving a cancer treatment for at least two months People who have given their written consent to take part, freely and with…

Women who are premenopausal and aged 18 or older. People who agree to take part in the study and sign the required consent form. People with a confirmed tissue diagnosis of early breast cancer that is hormone receptor positive (responding to estrogen and/or progesterone) and HER2-negative. People whose cancer has been…

Women aged 18 and over who have been diagnosed with breast cancer confirmed by a laboratory test (such as a biopsy). People with breast cancer whose treatment plan includes a chemotherapy drug called paclitaxel. People whose ability to carry out daily activities is rated above 2 on a standard medical scale used to…

Women aged 18 or older. People with invasive breast cancer that has been confirmed by a tissue biopsy or pathology test. People who have not yet received any systemic (whole-body) treatment for breast cancer. People whose breast cancer tests negative for oestrogen receptors (ER), progesterone receptors (PR), and HER2…

People who understand the study process, are willing to take part voluntarily, and are able to sign a consent form. Women aged 18 to 60 years old who have been diagnosed with primary invasive breast cancer in one breast only, confirmed by a tissue sample (biopsy), not including certain rare types such as occult…

People who are 18 years of age or older. People who have had their cancer confirmed through tissue testing, cell testing, or medical imaging, in line with the specific cancer types this trial is targeting. People who have given written consent before any trial-related procedures begin.

People who have a family-linked (inherited) form of breast cancer caused by a gene change, including but not limited to changes in the BRCA1, BRCA2, TP53, or PALB2 genes. People whose major organs (such as the heart, liver, and kidneys) are functioning well, with no serious problems. People who are fully active or…

People who are older than 18 years of age. People with a good general performance level, able to carry out normal daily activities with little or no restriction (ECOG performance score of 0 or 1). People with a life expectancy of at least 3 months. People who have been confirmed by tissue testing to have…

People who are at least 19 years old at the time of signing the consent form. People who have advanced breast cancer (either spread to nearby areas or to other parts of the body) that cannot be cured. People whose breast cancer is hormone receptor (HR)-positive and HER2-negative, based on the most recently tested…

People who are scheduled for a nipple-sparing mastectomy (breast removal that keeps the nipple) with immediate breast reconstruction for invasive breast cancer, a pre-cancerous condition called DCIS, or because they carry a BRCA gene mutation linked to breast cancer risk. People of any age. People whose nipple and…

People who speak and read English People between the ages of 21 and 70 years old People who have been diagnosed with stage 0 to 3 breast cancer within the past 5 years People who have finished all surgery, radiation, and chemotherapy (ongoing hormone-blocking medication is an exception) People who have been prescribed…

People aged 18 to 70 years old (any gender) People who have been confirmed through a needle biopsy to have invasive breast cancer at a specific stage (not spread to distant parts of the body, with tumour size and lymph node involvement within defined ranges — confirm with trial site) People whose breast cancer tests…

Adults aged 18 or older. People with a good general health and activity level, rated 0 or 1 on a standard medical scale called ECOG (meaning fully active or able to carry out light work). People whose breast cancer has been confirmed by a tissue sample (biopsy) and is hormone receptor-positive (meaning the cancer is…

People who are being treated with the medicine TUKYSA for an approved medical reason, as outlined on its official label. People who are receiving TUKYSA for the first time. People who are aged 18 or older. People who have signed and dated a consent form, showing they have been informed about all important aspects of…

People who have been diagnosed with breast cancer through a tissue sample examination and are currently receiving chemotherapy treatment, in line with established breast cancer treatment guidelines. People who are 18 years of age or older. People who are fully alert and able to communicate on their own. People who are…

People who have been diagnosed with breast cancer People who are currently receiving chemotherapy People whose chemotherapy treatment is scheduled on a cycle of every 21 days People who are 18 years of age or older People who do not have any difficulties with communication People who are willing to take part in the…

Women between the ages of 30 and 75. People who have had a lump or growth found on an ultrasound scan, are scheduled for surgery or a needle biopsy, and will receive a confirmed result from a tissue sample analysis. People who have had a full traditional Chinese medicine assessment completed using specialist…

People aged between 20 and 70 years old. Women who have been diagnosed with a primary invasive breast cancer through a biopsy. Women where the cancer is suspected to have spread to the lymph nodes in the armpit, and this has been confirmed through a needle sample or biopsy. People whose cancer has been clinically…

Women aged 18 years or older People who have been diagnosed with invasive breast cancer, confirmed by a tissue sample (biopsy) from the breast People whose tumor is a certain size or smaller, based on standard breast cancer measurements (known as clinical T2 or smaller) People with no signs — from physical examination…

People who are 18 years of age or older. People who have been diagnosed with breast cancer at pathologic stage I, II, or III. People whose breast cancer has spread to nearby lymph nodes in the region. People who have received chemotherapy and/or hormone (endocrine) therapy as part of their treatment. People who are…

People who are willing to take part voluntarily, have signed a consent form, and are able to follow the study requirements. People who are 18 years of age or older at the time of signing the consent form. People who have locally advanced or returning/spreading breast cancer and who have not previously received a type…

People who are over 18 years old, of any gender. People whose breast cancer has been confirmed by laboratory testing to be hormone receptor (HR) positive and HER2 negative, and has spread or returned (advanced stage). For the dose-finding stage of the trial: people whose doctor considers them currently suitable to…

People who have been diagnosed with breast cancer, at any stage of the disease. People who are 18 years of age or older. People who are able to read and communicate in Arabic, as the study involves interacting with an Arabic-language AI chatbot. People who are willing to take part in the study and engage with the AI…

The patient must be female and under 18 years old. The patient must have breast cancer that has been confirmed through a tissue sample analysis. The patient's breast cancer must be HER-2 negative, meaning it can be either hormone receptor-positive or triple-negative (confirm with trial site if unsure which type…

People who are older than 18 years of age. People who are having a mastectomy (surgical removal of the breast) with immediate reconstruction using a special dye-based imaging technique called ICG-NIR. People who are mentally able to understand and participate in the study. People who have given written agreement to…

People who have been confirmed by tissue testing to have invasive breast cancer at clinical stage II or III. People aged between 18 and 70 years. People who are generally well enough to carry out daily activities with no or minimal limitations (as measured by a standard health performance scale called ECOG, scoring 0…

The cancer has been confirmed by a pathologist as HER2-positive or HER2-low advanced breast cancer (based on specific test results). The person is older than 18 years. Brain metastases (cancer that has spread to the brain) have been newly diagnosed and confirmed by a special type of brain scan (enhanced MRI), with…

Women aged 18 or older. People who have been diagnosed with HER2-positive advanced breast cancer, confirmed by laboratory testing. People who have been newly diagnosed with cancer that has spread to the brain, with at least one measurable tumour in the brain. People who have not yet received any systemic (whole-body)…

People who are willing to take part in the study and sign a consent form agreeing to participate. Female patients who are 18 years of age or older at the time of signing the consent form. Women who could potentially become pregnant must have a negative blood pregnancy test within 7 days before joining, and must agree…

A chest CT scan using a specific type of imaging called "quark energy spectrum CT" was done within 1 week before starting the study. People aged 18 or older. People who are suspected of having breast cancer. People who have signed a consent form agreeing to take part.

Members of churches taking part in this study, located in the North East of England, Leeds, or Scotland. People who identify as Black. Women between the ages of 25 and 74. Men between the ages of 50 and 74. People who are not fully up to date with all the cancer screening tests they are eligible for — for example, a…

People who are 18 years of age or older at the time of signing the consent form, regardless of gender. People who have been diagnosed with either triple-negative breast cancer (a type of breast cancer that lacks three specific receptors) or hormone receptor-positive, HER2-negative breast cancer (a type that responds…

Patients must be female and aged 65 years or older. Patients must have been diagnosed with early-stage breast cancer (confirmed by tissue testing) that has been surgically removed, with the cancer testing positive for oestrogen receptors at 50% or higher. In addition to the above, patients must also have either 4 or…

People who have been confirmed by tissue testing to have hormone receptor (HR)-positive, HER2-negative breast cancer. People whose cancer is at clinical stage II or III (not spread to distant parts of the body). Women who are post-menopausal, or men with breast cancer. People whose cancer treatment plan includes…

People who are scheduled for planned (non-emergency) breast surgery People who are 18 years of age or older People who are female People with a body mass index (a measure of body weight relative to height) of 30 or below People who are willing and able to give their full informed consent to participate People who are…

People who are female, aged 18 to 70 years old at the time of signing the consent form. People whose general physical health and ability to carry out daily activities is rated as 0 or 1 on a standard medical scale (meaning fully active or able to carry out light activity). People with an estimated life expectancy of…

Women aged 18 or older who have been diagnosed with breast cancer at any stage (from very early to advanced). Women who are currently receiving chemotherapy (at least two rounds) or who finished chemotherapy at least six months ago. Women who have reported memory or thinking difficulties, with a score below 54 on a…

Women aged 18 or older People whose breast cancer was classified at a advanced local stage (spread to nearby tissue or lymph nodes) before treatment, regardless of hormone receptor type People whose cancer tested positive for HER2, confirmed by specific laboratory tests (IHC 3+, or IHC 2+ with ISH+) People whose…

The study is open to women who have had breast reconstruction surgery. Women who finished chemotherapy at least one month before joining the study may be considered. Women who have ongoing pain following cosmetic breast surgery may be considered. People who agree to take part in the study at least one week after their…

People who are able to understand and sign a dated consent form approved by an ethics board before any trial-related procedures begin. Women aged 18 or older who have advanced breast cancer. People whose breast cancer has been confirmed by laboratory testing and is either unable to be removed by surgery or has spread…

People who are female and aged 18 or older. People who have been diagnosed with triple-negative breast cancer (a specific type of breast cancer), confirmed through a tissue or cell sample. People whose cancer cannot be surgically removed, or has spread to other parts of the body. People whose cancer tests positive for…

People aged 18 to 75 years old who have advanced or metastatic breast cancer. People with a good general health and activity level, as measured by a standard performance score of 0 or 1 (meaning mostly active and able to carry out daily activities with little or no restriction). People who have at least one tumour or…

Women between 18 and 75 years old who have previously been diagnosed with stage 0 to stage III breast cancer. Women who are currently in the survivorship phase of breast cancer, no matter what type of medical or surgical treatment was received. At least six months must have passed since finishing primary treatment.

Women between the ages of 18 and 75 (including those exact ages). People with breast cancer that cannot be surgically removed or has spread to other parts of the body, where the cancer has been confirmed by laboratory testing to have high, low, or very low levels of a protein called HER2. People whose cancer has…

Women between 18 and 70 years of age People whose breast cancer has been confirmed by laboratory testing of tissue samples to be HER2 positive People who have been diagnosed with stage II or stage III breast cancer People who have at least one tumour that can be measured using standard imaging guidelines People whose…

People diagnosed with stage II or III triple-negative breast cancer (a specific type of breast cancer that lacks three particular receptors), confirmed through laboratory testing of tissue samples. The cancer must have tested as having very low levels of estrogen and progesterone receptors (less than 1%) on laboratory…

People who have been diagnosed with a specific type of breast cancer (called invasive ductal carcinoma) that is ER-positive and HER2-negative, confirmed by a tissue sample, and meets at least one of the following: the tumour is a certain size with lymph node involvement and a moderate or high grade (with low hormone…

Adults between 18 and 75 years old (inclusive), of any gender. People with a good general health and activity level, rated 0 or 1 on a standard medical scale used to measure how much a condition affects daily activities (confirm with trial site). People whose doctor estimates they are expected to live for more than 3…

Women between the ages of 18 and 80 years old People who have swelling in one arm (not both) caused by fluid buildup following breast cancer surgery People whose arm swelling has been diagnosed at a recognised stage of severity (ranging from very early or hidden swelling through to more advanced swelling) People who…

People who have had hormone receptor-positive, HER2-negative early-stage breast cancer (a specific type of breast cancer based on its biological features). People who received treatment between January 2011 and December 2023. People whose medical records contain detailed information about their cancer and results from…

People who have been newly diagnosed with hormone receptor positive, HER2 negative invasive breast cancer, or a specific early form called DCIS with microinvasion, confirmed by a tissue sample (biopsy). People who are postmenopausal and older than 55 years of age. People whose main breast tumour is no larger than 3 cm…

Women with breast cancer aged 18 or older, whether they have gone through menopause or not. People with a confirmed breast cancer type that is hormone receptor-positive (meaning the cancer is fuelled by hormones) and HER2-negative (a specific protein is not overactive), based on laboratory testing of tissue samples.…

People who are willing to take part voluntarily, are able to sign a written consent form, and are prepared to follow all trial procedures. Female participants who are aged 18 to 75 years old on the day they sign the consent form. People who have been confirmed by laboratory tissue testing to have a specific type of…

Female patients admitted at the South Egypt Cancer Institute who have been diagnosed with breast cancer, confirmed through clinical examination, imaging, and laboratory/tissue testing.

Adults aged 18 to 75 years who are in good general health and able to carry out normal daily activities with little or no difficulty (ECOG performance score of 0 or 1). People with a confirmed diagnosis of HER2-negative breast cancer that has spread to nearby tissues or other parts of the body, where the cancer is…

People who are willing to take part voluntarily and sign a consent form People aged 18 or older People who have been confirmed through laboratory testing (tissue or cell samples) to have breast cancer that cannot be surgically removed, has come back locally, or has spread to other parts of the body People whose breast…

People who have signed a written consent form agreeing to take part in the trial People who are enrolled in the French Social Security system People who have breast cancer or a digestive (gut-related) cancer, and whose doctor is considering treating them with a type of chemotherapy called a fluoropyrimidine OR people…

People who have been diagnosed with HER-2 positive breast cancer (confirmed through laboratory testing of tissue samples using specific methods called immunohistochemistry or FISH), at an advanced stage. People whose cancer has shown a complete response — meaning scans using PET-CT or contrast-enhanced CT have shown…

Adults aged 18 to 70 years who are generally well enough to carry out daily activities with little or no limitation (a measure doctors call ECOG performance status 0–1). People diagnosed with breast cancer that has grown to a certain size or spread to underarm lymph nodes, based on standard staging categories…

People with a good general health and activity level, rated 0 or 1 on a standard performance scale (called the ECOG scale). People expected to live for more than 12 weeks. People who have been diagnosed through tissue testing with invasive breast cancer that has a low level of a protein called HER2 (specifically, test…

A person must have signed a written consent form before any trial-related procedures take place (if someone is physically unable to sign, a witness of their choice can sign on their behalf). Adults aged 18 years or older. A person must have a confirmed diagnosis of breast cancer that has spread to other parts of the…

Women between 18 and 70 years old. People with a performance status score of 0 or 1 on the ECOG scale, which means they are fully active or have only minor limits on physical activity (confirm with trial site). People whose doctors expect them to live for more than 12 weeks. People whose breast cancer has been…

People aged 18 or older at the time of signing the consent form. People who have been confirmed through a tissue or cell sample to have triple-negative breast cancer (a type of breast cancer that does not respond to certain hormone-based treatments), based on their most recent biopsy or pathology results. People whose…

Adults aged 18 or older. People who have been diagnosed with a specific type of breast cancer — hormone receptor-positive (HR+) and HER2-negative — that has either spread to other parts of the body or cannot be surgically removed, confirmed through a tissue or cell sample test. People whose cancer continued to grow or…

The person must sign a consent form before enrolling in the trial. People between 18 and 75 years of age. People who have been diagnosed with breast cancer confirmed through laboratory testing of tissue samples. People with breast cancer whose platelet count has dropped as a result of chemotherapy (a condition called…

The person has been diagnosed with invasive breast cancer confirmed by tissue testing. The cancer is at a locally advanced stage (larger tumour or spread to nearby lymph nodes, but not to distant parts of the body), and is either a hormone-sensitive type (HER2-negative) or triple-negative type, and the tumour did not…

People who are willing to take part voluntarily, understand what the trial involves, and agree to follow the study requirements. People aged 18 years or older. Female participants must be postmenopausal and meet the specific trial requirements (confirm with trial site). People whose general health and ability to carry…

Women between the ages of 18 and 75 years. People with a confirmed diagnosis of HER2-positive advanced breast cancer, verified through laboratory testing of tissue or cell samples. People with brain metastases (cancer that has spread to the brain) confirmed by imaging, with two separate groups in the trial: Cohort A…

The patient, or their legal representative, must be able to understand the study's purpose and must have signed a consent form before any study procedures begin. People aged 18 or older at the time of signing the consent form. People with breast cancer that has been confirmed by imaging to be locally advanced and…

People diagnosed with a type of breast cancer that is hormone receptor positive (HR+) and HER2 negative that has spread to other parts of the body. People who are currently on their first or second treatment for this cancer. People with a life expectancy of at least 12 months. Female only. Aged 18 years or older. Able…

People who agree to undergo a type of specialised scan called an 18F-FAPI PET/MRI examination People who have been diagnosed with breast cancer that has grown into nearby tissue (locally invasive breast cancer) People who are scheduled to receive chemotherapy or other systemic treatment before surgery (called…

People who have had a standard breast ultrasound scan within the past month, or who have one scheduled within the coming month. People with a history of breast cancer or previous breast surgery may also be considered. People who are female. People aged between 18 and 85 years old. People who are able to understand…

Adults aged 18 to 75 years. People with a good general health and activity level, rated 0 or 1 on a standard oncology performance scale (ECOG). People with a laboratory-confirmed invasive breast cancer where the primary tumour is larger than 2 centimetres, and the cancer is either early-stage or locally advanced (but…

People who have been diagnosed with primary breast cancer confirmed through a tissue or cell sample test. People who are aged 18 years or older but younger than 80 years. People who have complete and reliable medical records available. For those who had COVID-19, there must be documented proof of a positive test…

A person must provide written consent to participate before joining the trial. Participants must be 18 years of age or older. A confirmed diagnosis of a specific type of breast cancer (hormone receptor-positive and HER2-negative) is required, based on laboratory testing, where the cancer cannot be treated with surgery…

People diagnosed with localized invasive breast cancer that is estrogen receptor positive (ER+, meaning at least 10% of cancer cells test positive) and HER2 negative, at any grade, and classified as stage I to III at the time of surgery (including those who received treatment before surgery). People whose cancer…

Women with breast cancer between the ages of 18 and 75 People whose overall physical health falls within a certain range as assessed by an anaesthesia classification system (ASA levels I, II, or III — confirm with trial site if unsure which category applies) People who are scheduled for a planned breast cancer…

People aged 18 to 75 years, of any gender. People whose breast cancer has been confirmed by tissue testing to be hormone receptor-positive and HER2-negative (HR+/HER2-), based on specific international testing guidelines. People whose breast cancer tissue is either a high-grade (grade 3) tumour, or a mid-grade (grade…

People who are female and aged 18 or older. People who have been diagnosed with breast cancer, confirmed through laboratory testing of tissue or cell samples. People whose tumor has been tested and found to be HER2-positive, based on specific lab results (IHC showing +++ , or IHC++ confirmed by a further test called…

Women aged between 18 and 75 years. People who have been diagnosed with invasive breast cancer in one breast only, confirmed by a tissue biopsy. People whose cancer was found to be early stage (Stage I) after surgery, meaning the tumour was no larger than 2 cm and had not spread to the lymph nodes. People whose cancer…

Women between the ages of 30 and 60 years old. Women who have had a mastectomy (surgical removal of one breast) on one side, at least three months after the surgery. Women where measurements show that the arm on the side of surgery has more than 10% more volume than the arm on the unaffected side. Women who have…

The person must be female. The person must be 40 years of age or older. The person must be able to understand and agree to take part in the study. The person must have had a mammogram (a breast X-ray screening) at some point in the past.

People who have been diagnosed with breast cancer that has spread or cannot be surgically removed, and whose cancer tests show it is hormone receptor (HR) positive and HER2 negative (based on specific laboratory testing guidelines). People whose cancer has continued to grow, or who could not tolerate, at least one…

Adults over 18 years old who live in the community (not in a care facility) People who have recently been diagnosed with breast cancer People who are scheduled to have surgery for breast cancer People who speak English and are able to follow the study instructions

Women between 18 and 70 years of age (inclusive). People scheduled for a specific type of breast removal surgery (done through small incisions, preserving the nipple) on one or both breasts, with immediate breast reconstruction using an implant placed above the chest muscle, and the option of breast enlargement on the…

People who are female and aged 18 years or older. People who have been diagnosed with a single-site, surgically treatable form of invasive breast cancer. People whose treating doctor has determined them to be suitable for breast-conserving surgery (surgery that removes the tumour while keeping most of the breast).…

People must give written consent to take part in all study procedures before anything begins, as required by local rules. People must have untreated, one-sided (not both breasts) primary breast cancer confirmed by a core biopsy (a fine-needle aspiration alone is not enough, and an open surgical biopsy is not allowed).…

The person must have signed an informed consent form and be willing to follow the trial requirements. The person must be between 18 and 70 years old. The person must have a good general health status (low symptom burden) and a life expectancy of more than 6 months. The person must have breast cancer that has been…

Women aged 18 or older who have been diagnosed with breast cancer that has not spread to other parts of the body and who are scheduled to have surgery. There must be enough tumor tissue and nearby normal tissue left over after standard diagnostic testing to be used for research. The person must be willing and able to…

Women aged 18 or older People with a confirmed breast cancer diagnosis based on imaging and pathology results People who are about to receive their first course of a type of chemotherapy called anthracycline-based chemotherapy

Adults aged 18 or older, of any gender. People who have locally advanced or metastatic triple-negative breast cancer (a specific type of breast cancer that has spread or cannot be surgically removed). People who have already received at least two prior chemotherapy treatment courses for their breast cancer (if cancer…

People with breast cancer who had a delayed breast reconstruction procedure (using an implant, performed through small incisions using a camera) after a simple mastectomy, at one of the participating centres between July 2024 and August 2025, where the reconstruction was done at least 6 months after the original…

Participants must be 18 years of age or older. Participants must have a confirmed diagnosis of stage II or III triple-negative breast cancer (a type of breast cancer that tests negative for certain receptors), confirmed through a tissue sample analysis. Participants must have a good general health and activity level…

A normal mammogram result within the 90 days before enrolling in the trial. Breasts that are classified as "heterogeneously dense" (Class C) or "extremely dense" (Class D) on a mammogram report. A 5-year breast cancer risk score of more than 3%, as estimated by a tool called MRS. Female. Between 25 and 55 years of age…

Phase 1 Adults aged 18 or older. People with a confirmed diagnosis of triple-negative breast cancer (TNBC) — a specific type of breast cancer identified by low levels of certain receptors and no HER-2 gene amplification — who are about to begin chemotherapy before surgery. People whose general health and ability to…

People who have been diagnosed with invasive breast cancer confirmed through laboratory tissue testing. People whose blood tests show traces of cancer DNA (called ctDNA) after completing their main cancer treatments. People who have had surgery to remove the breast cancer, with the lymph nodes under the arm also…

People who have been diagnosed with breast cancer. People who are experiencing pain. People who are experiencing anxiety. People who have completed at least one cycle (session) of chemotherapy. People who are receiving the same type of chemotherapy as other participants in the trial. People who did not have an anxiety…

The cancer must be stage II or III at the time of first diagnosis, based on the AJCC 8th edition staging system. Patients must be female and between 18 and 75 years of age (inclusive). The cancer must have been confirmed by laboratory testing to be HR+/HER2+, meaning the estrogen receptor (ER) is positive in more than…

You have been diagnosed with breast cancer that was confirmed through a laboratory tissue test You were 50 years old or younger when you were first diagnosed You were still having periods (or had hormone levels showing you were premenopausal) at the time of diagnosis You had surgery aimed at removing all the cancer…

People aged 18 or older. People who are covered by, or entitled to, a social security system. People who have agreed to take part in the study and have signed a written consent form. People who have had an 18F-FDG PET/CT scan (a type of full-body imaging scan) as part of checking the spread of a specific type of…

People who are 18 years of age or older. People who have been diagnosed with breast cancer that has spread locally or to other parts of the body, confirmed through a tissue or cell sample test. People whose cancer is hormone receptor (HR) positive, meaning the cancer cells show at least 1% presence of estrogen and/or…

Women with breast cancer that cannot be removed by surgery and has either spread to nearby areas or to other parts of the body (metastatic). People with a confirmed diagnosis of breast cancer that is hormone receptor (HR)-positive and HER2-negative. Women who are postmenopausal. People who have not previously received…

People who have been diagnosed with breast cancer confirmed through a core-cut biopsy (a type of tissue sample taken with a needle). People for whom a team of medical specialists has recommended breast-conserving surgery (surgery that removes the tumour while keeping most of the breast). People whose surgery is…

A person must have breast cancer that has been confirmed through laboratory testing of tissue samples. A person must have developed nerve-related side effects (such as tingling, numbness, or pain) of at least a mild level after receiving a chemotherapy treatment that includes a drug from the taxane family, and must…

Being registered with Family Health Center No. 1 in Ardahan Province Being a woman between the ages of 20 and 69 Being able to read and write Not having been diagnosed with breast cancer Not having a mental health condition or communication difficulty that would affect participation Having access to a phone for…

Women between 18 and 75 years old. People with a good general level of physical fitness and ability to carry out daily activities (a medical performance score of 0 or 1 out of 4). People whose breast cancer has been confirmed by a tissue sample (biopsy) as an invasive cancer, regardless of the specific type. People…

People aged 18 years or older. People who have had breast cancer surgery where at least one lymph node was removed. People who have been diagnosed with stable lymphedema (fluid build-up causing swelling) in one arm, related to breast cancer treatment. People who are willing and able to take part in exercise. People…

The person joining (or their legal representative, if applicable) must be able to understand the purpose of the study and must have signed a written consent form before any study procedures begin. Participants must be 18 years of age or older at the time of signing the consent form. Participants must have a general…

People who are older than 18 years old People whose breast cancer has been assessed as stage cT1 or cT2 (an early stage of tumour size — confirm with trial site) People whose lymph nodes near the armpit have been assessed as cN0, meaning no cancer has been detected in those nodes before the operation People who have…

People who are willing to take part voluntarily, sign a consent form, and follow the study requirements. People aged 18 to 75 years old at the time of signing the consent form. People with a good general health and activity level (ECOG performance score of 0–1) and an expected survival of more than 6 months. People…

Adults aged 18 or older. People who have been diagnosed with invasive breast cancer (early to locally advanced stages, known as stages I to III), confirmed through a tissue sample test. People whose treatment plan includes chemotherapy before or after surgery that contains one of two specific types of drugs — an…

Women between the ages of 18 and 70. People who have been diagnosed with breast cancer on one side only, confirmed by a biopsy or tissue test before surgery. People who are planned to have a nipple-sparing mastectomy (removal of the breast while keeping the nipple) with an implant placed in front of the chest muscle…

People who are 18 years of age or older. People who are scheduled to have planned (non-emergency) surgery to remove breast cancer. People whose overall physical health before surgery falls within a range that anaesthesiologists classify as suitable for elective procedures (ASA classification I–III — confirm with trial…

People who have been diagnosed with breast cancer (on one side only, at stages I to III, not the inflammatory type) and have had either breast-conserving surgery or a full mastectomy, and have received or are planned to receive standard follow-up treatments as recommended by current guidelines. People who are…

People who are female and aged 18 or older People who have undergone breast-conserving surgery or full breast removal, along with surgery to remove or check underarm lymph nodes People whose surgical margins were clear, meaning no cancer cells were found at the edges of the removed tissue People whose cancer fits one…

People who have been diagnosed with breast cancer confirmed through a surgical or biopsy tissue sample. People who have had a specific type of breast imaging scan (called a DCE-MRI) done within two weeks before their surgery. People who have not received any treatment before their initial DCE-MRI scan.

People who are between 18 and 69 years of age. People who are postmenopausal, confirmed through a blood test measuring estrogen levels or other clinical assessment. People who have been diagnosed with a specific type of breast cancer called infiltrating ductal carcinoma, confirmed by tissue testing, of any grade.…

People aged 70 years or older. People who have been diagnosed with invasive breast cancer confirmed through a tissue sample (biopsy). People whose cancer has been assessed by mammogram and ultrasound as an early-stage tumour (classified as cT1N0M0), where the cancer is sensitive to hormones (ER-positive) and does not…

People (male or female) who have been diagnosed with DCIS or LCIS (non-invasive breast conditions) found through a core biopsy. The breast lesion must be a single area measuring at least 1 cm and no more than 5 cm, seen on imaging such as a mammogram, MRI, or ultrasound, with no sign of invasive cancer on biopsy and…

People who have been diagnosed with a type of breast cancer that is hormone receptor-positive (HR+), confirmed by laboratory testing. People who are 18 years of age or older. People who have been taking a type of hormone-blocking medication called an aromatase inhibitor (such as anastrozole, letrozole, or exemestane)…

Women between 18 and 75 years of age. People who are generally well enough to carry out daily activities with little or no limitation (a measure of overall health used in cancer care, rated 0 or 1 on a standard scale). People whose main breast tumour measures more than 1 cm across. People with a confirmed diagnosis of…

Women between the ages of 18 and 75 People with a confirmed diagnosis of invasive breast cancer (confirmed through tissue testing) People whose breast cancer has spread to the lymph nodes in the armpit, requiring surgical removal of those lymph nodes People with a Body Mass Index (BMI) of 25 or higher (confirm with…

Women aged 18 to 75 who have not previously received any treatment for their breast cancer. People with a good general level of physical functioning, able to carry out normal daily activities with little or no limitation (confirm with trial site for specific scoring criteria). People who have been diagnosed with a…

Adults aged 18 or older. People who have been diagnosed with HER2-positive advanced breast cancer, confirmed through a tissue or cell sample test, with specific test results showing a high level of the HER2 protein. People whose general health and ability to carry out daily activities falls within an acceptable range…

Women between 30 and 75 years of age. People who have been diagnosed with breast cancer confirmed through a tissue sample test. People who are planned to receive a type of chemotherapy that includes drugs called anthracyclines and/or trastuzumab. People assessed by their doctor as having a high or very high chance…

The person has signed and dated a Patient Informed Consent Form before any trial-related screening takes place. The person is female with a known menopausal status at the time of joining the trial. The person is aged 18 to 70 years old at the time of signing the consent form. The person has been diagnosed with a…

Women between the ages of 18 and 80 People diagnosed with invasive breast cancer at stage I, II, or III People who are scheduled to have surgery as part of their treatment People whose surgery is planned for at least 3 weeks from the time of joining the trial People who have not received any cancer treatment (such as…

Women aged 18 to 50 years old. Women who had not yet gone through menopause at the time their breast cancer was diagnosed (based on self-reporting). People diagnosed with breast cancer (in one or both breasts) who were treated at the Institut Bergonié with chemotherapy (with or without targeted therapy or…

People who are able to understand and sign consent forms for the study. People who have already had a standard breast biopsy marker placed during a previous procedure.

Women aged 18 years or older. People who have been diagnosed with invasive breast cancer, confirmed through a tissue biopsy. People whose breast cancer tumor tests positive for estrogen receptors (meaning at least 10% of tumor cells show estrogen receptor activity), measured using standard guidelines; any level of…

Willingness to sign and date a consent form. Willingness to follow all study procedures and be available for the full duration of the study. Being 18 years of age or older. Being female as recorded on a birth certificate. Ability to read and speak English or Spanish. Having a recent diagnosis of Stage 1 to Stage III…

People who have been diagnosed with breast cancer (stage 0 to III) and are aged 20 or older, with no signs that the cancer has spread or come back. People who finished surgery, targeted therapy, chemotherapy, or radiotherapy at least 3 months ago. People who have been taking anti-hormone inhibitors and traditional…

Adults aged 18 or older People who have been diagnosed with advanced breast cancer, confirmed through laboratory testing of tissue or cell samples People whose breast cancer has tested negative for HER2, and positive for hormone receptors (HR+), in either the original tumour or a secondary (metastatic) site People who…

People who have signed a consent form agreeing to take part in the study. Female patients who are 18 years of age or older on the day they sign the consent form. People whose cancer can be measured or assessed using standard imaging criteria. People who are generally able to carry out daily activities with little or…

People aged 18 or older, of any gender. People diagnosed with a specific type of breast cancer called invasive breast carcinoma of no special type, where the cancer is hormone receptor-positive and HER2-negative (confirm with trial site for exact test results). People whose cancer has not spread to distant parts of…

People who are female and between 18 and 75 years old. People whose post-surgery tissue testing confirmed a type of breast cancer that is hormone receptor-positive (HR+) and HER2-negative, meaning the cancer responds to hormones but not to the HER2 protein — defined as at least 10% of cancer cells testing positive for…

People who have been diagnosed with HER-2-positive breast cancer (confirmed by a laboratory test on a tissue sample) that has spread to the brain for the first time. People who have a level of physical functioning rated as 0, 1, or 2 on a standard medical scale (ECOG), meaning they are fully active to somewhat limited…