Breast Cancer Trial, Recruiting NCT05592938 Sponsor: University Health Network, Toronto Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT05592938
Recruiting Not Applicable 🇦🇺 Australian site

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are over 18 years of age
  • People who have had a breast cancer return in the same breast, or a new breast cancer forming (either a non-invasive type called DCIS or an invasive cancer)
  • People whose tumour measured less than 3.0 cm across at its widest point when examined after removal, including all parts of the tumour (both invasive and non-invasive)
  • People who completed their previous course of radiotherapy to the whole or part of the breast more than 5 years ago (previous radiotherapy to the lymph node area is also allowed)
  • People whose cancer has not spread to the lymph nodes, based on clinical assessment
  • People whose surgery removed the tumour with clear edges, meaning no cancer cells were found at the outer edges of the removed tissue
  • People who have fully recovered from surgery, with the wound completely healed and no signs of infection

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose cancer has appeared in more than one separate area of the breast (though cancer in multiple spots within the same section of the breast is allowed)
  • People whose tumour is made up entirely of a type called lobular carcinoma
  • People with a very advanced local tumour classified as T4 (confirm with trial site)
  • People whose cancer has spread to the lymph nodes or to other parts of the body
  • People who have a serious non-cancer illness affecting the heart, lungs, or immune system (such as lupus or scleroderma) that would make radiotherapy unsafe
  • People who are currently pregnant or breastfeeding
  • People who have a breast implant or a pacemaker on the same side as the affected breast
  • People who are not able to start radiotherapy within 16 weeks of their breast surgery (or last breast procedure), or within 12 weeks of finishing their last round of chemotherapy
  • People where the surgical site cannot be clearly identified for radiation targeting purposes (special reconstructive surgery is allowed if the tumour site has been clearly marked with surgical clips)
  • People with a psychiatric condition that would prevent them from giving informed consent or following the trial requirements
  • People who experienced moderate or severe long-term skin reactions from their previous radiotherapy treatment
  • People who have had breast cancer in both breasts, either currently or in the past

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 31 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Danielle Rodin, MD, Princess Margaret Cancer Centre

Phone: (416) 946-6513

Australian sites

Peter MacCallum Cancer Centre, Melbourne, Victoria
61 3 8559 8635

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
27 June 2023
Est. completion
27 June 2027

Where this trial is recruiting

🇦🇺 Australia 🇧🇷 Brazil 🇨🇦 Canada 🇨🇱 Chile 🇮🇱 Israel 🇮🇹 Italy 🇯🇴 Jordan Kenya 🇲🇾 Malaysia 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Grade ≥3 toxicity associated with treatment

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov