Phase 2 Mesothelioma Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older
- You are fairly active and able to care for yourself, with little or no limitation on daily activities (this is measured by a standard scale called ECOG, scored 0 or 1)
- You are willing and able to sign a consent form and follow all study requirements
- Your cancer has been confirmed by a lab test (biopsy or similar) and has either spread to nearby tissue or to other parts of the body
- Your major organs (such as liver, kidneys, and bone marrow) are working well enough
- Your cancer can be measured on a scan (CT or MRI)
- Your doctor expects you to live for at least 12 weeks
- If you are a woman who could become pregnant, you must have a negative pregnancy test before starting the study
- You agree to use highly effective birth control during the study (required for women who could become pregnant)
Who may not be able to join:
- You have received cancer treatment, chemotherapy, or been in another clinical trial within the last 4 weeks (or a shorter period for certain targeted therapies — confirm with trial site)
- You have had radiation therapy within the last 2 weeks, or have a history of lung inflammation caused by radiation
- You have had high-dose radiation to the lungs (over 30Gy) within the last 6 months
- Your cancer has spread to the brain and is currently active; however, previously treated and stable brain metastases may be considered (confirm with trial site)
- You have had another cancer within the last 3 years, unless it was a type that has been fully cured
- You are taking steroid medicines (such as prednisone) at higher doses long-term, or other medicines that suppress your immune system
- You have a significant active autoimmune disease (where your immune system attacks your own body), or a condition that could get worse with immune-based treatments
- You have serious heart, lung, or other major organ disease
- You have a known hepatitis B or hepatitis C infection
- You are pregnant, breastfeeding, or planning to become pregnant during the study
- You have previously received an organ or tissue transplant from another person
- You currently have an active infection that requires treatment with antibiotics or other medicines
- You have a mental health, emotional, or other medical condition that might make it hard to follow the study requirements
- You have a known serious allergy to any ingredient in the study drug(s)
- In the opinion of the study doctor, any other medical condition that could make the treatment unsafe or make results difficult to interpret
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Nina Merchant, Medicenna Therapeutics
Phone: 604-340-3081
Australian sites
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
4 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
MDNA11 Recommended Dose for Expansion for monotherapy (mRDE) and Recommended Dose for Expansion for combination (cRDE); Incidence of Treatment Related Adverse Events (TRAEs); Incidence of Treatment Emergent Adverse Events (TEAEs)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.