Brain Cancer Trial, Recruiting NCT03137095 Sponsor: University of Rochester Condition: Brain Cancer
Back to Brain Cancer

Brain Cancer Trial, Recruiting

NCT03137095
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For breast cancer patient participants:

  • Women who have been diagnosed with invasive breast cancer that has not spread to other parts of the body (stages I through IIIC)
  • People who are scheduled to start a chemotherapy treatment plan using the drugs Adriamycin and Cytoxan
  • People who have never received chemotherapy before
  • People who are able to speak and read English
  • People aged 21 or older
  • People who are willing to sign a written consent form

For control participants (people without breast cancer who take part for comparison):

  • Women who are within 5 years of age of a breast cancer participant in the trial
  • People who are able to speak and read English
  • People aged 21 or older
  • People who are willing to sign a written consent form

Who may not be able to join:

For breast cancer patient participants:

  • People who are currently in hospital, or who have been hospitalised in the past year due to a mental health condition
  • People who have been diagnosed with a disease that causes the brain or nervous system to break down over time, such as Alzheimer's or Parkinson's disease
  • People who have a condition affecting the brain or central nervous system, such as multiple sclerosis or a movement disorder
  • People who have had a mini-stroke (TIA) or stroke within the past year, or who still have symptoms from a past TIA or stroke (confirm with trial site)
  • People who are scheduled to receive radiation treatment at the same time as chemotherapy
  • People who are colorblind

For control participants:

  • People who are currently in hospital, or who have been hospitalised in the past year due to a mental health condition
  • People who have been diagnosed with a disease that causes the brain or nervous system to break down over time, such as Alzheimer's or Parkinson's disease
  • People who have a condition affecting the brain or central nervous system, such as multiple sclerosis or a movement disorder
  • People who have had a mini-stroke (TIA) or stroke within the past year, or who still have symptoms from a past TIA or stroke (confirm with trial site)
  • People who have previously been diagnosed with cancer or received chemotherapy
  • People who are colorblind

For the optional brain scan sub-study:

  • MRI safety screening is required to determine whether participation in the optional scanning portion of the study is appropriate (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Michelle C. Janelsins, Ph.D.,M.P.H., University of Rochester

Phone: 585-273-3998

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 February 2017
Est. completion
31 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Cognitive function (memory, concentration, attentiveness) will be assessed by computerized cognitive assessments and associated with inflammation and neurotoxicity markers

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov