Phase 2 Tuberculosis Trial, Recruiting NCT03159364 Sponsor: Shenzhen Geno-Immune Medical Institute Condition: Tuberculosis
Back to Tuberculosis

Phase 2 Tuberculosis Trial, Recruiting

NCT03159364
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have evidence of infection with one of these viruses: CMV, EBV, ADV, BKV, or another known virus (confirmed by a lab test), and standard antiviral medicines have not worked or cannot be used.
  • Your virus levels in the blood have been rising across two blood tests taken at least 24 hours apart, with a level of 1,000 or more copies per ml of blood.
  • Your blood counts have recovered to a basic level: your neutrophils (infection-fighting white blood cells) and platelets are above certain minimum levels (confirm with trial site).
  • You have symptoms of a viral disease affecting organs or tissues — such as fever, diarrhea, or swollen lymph nodes — confirmed by lab tests on body fluid or a tissue sample, regardless of blood virus levels.
  • You (or your guardian) have signed a written consent form before the trial begins.
  • Your kidney and liver are working well enough, based on blood test results being within acceptable ranges (confirm with trial site).
  • If the immune cells used in the treatment come from a donor, that donor must be healthy, have normal blood counts, test negative for HIV, hepatitis B, hepatitis C, and tuberculosis, and must not have had chemotherapy, radiotherapy, steroids, or certain antibiotics recently (confirm with trial site).

Who may not be able to join:

  • You have tested positive for hepatitis C (HCV), hepatitis B (HBV), HIV, or HTLV.
  • You are experiencing moderate to severe graft-versus-host disease (a complication sometimes seen after a transplant), graded at level II to IV (confirm with trial site).
  • You have a known intolerance or allergy to albumin (a protein used in the treatment preparation).
  • Your doctors expect you to live for less than 4 weeks.
  • You have taken part in another experimental cell therapy trial within the past 30 days.
  • You have a positive pregnancy test.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Lung-Ji Chang, PhD, Shenzhen Geno-Immune Medical Institute

Phone: +86 0755-86573763

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shenzhen Geno-Immune Medical Institute
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
31 December 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Using CTCAE 4 standard to evaluate the level of adverse events after receiving autologous or allogenic pathogen-specific CTL infusion; Viral load change after Virus-CTL infusion

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov