Brain Cancer Trial, Recruiting NCT03184038 Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT03184038
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with a solid tumour cancer that has been confirmed by a medical test (not small cell lung cancer or germ cell tumour)
  • You are reasonably active and able to carry out daily activities, as measured by a standard health scale (confirm with trial site)
  • You have between 1 and 10 cancer spots that have spread to the brain, with no more than two of those spots being 3 cm or larger in size
  • The largest brain tumour spot or surgical removal site measures no more than 6 cm across
  • Your kidneys are functioning well enough, based on blood test results (confirm with trial site)
  • You are in good enough general health and emotional wellbeing to complete all parts of the study, including memory and thinking tests at set points during the trial
  • If you are a woman who could become pregnant, you have had a negative pregnancy test within the last 21 days before joining
  • If you are a woman who could become pregnant, or a man, you must agree to use reliable contraception during the study and for 4 months after the last treatment
  • You are able to give your own written consent to take part and can speak English

Who may not be able to join:

  • You have been diagnosed with a brain tumour that started in the brain, such as a glioma or other primary brain tumour
  • You have had brain surgery within the last 14 days
  • You are planned to receive chemotherapy at the same time as the radiation treatment used in this trial
  • The cancer has spread to the lining around the brain or spinal cord
  • You are having more than one seizure per week despite taking seizure medication, and this has been happening for the past 2 months
  • You are currently pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Wenyin Shi, MD, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Phone: (215) 955-6702

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Registry
ClinicalTrials.gov
Start date
21 February 2017
Est. completion
30 September 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Neurocognitive function as measured by neurocognitive decline on a battery of tests

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov