Phase 2 Lung Cancer Trial, Recruiting NCT03356808 Sponsor: Shenzhen Geno-Immune Medical Institute Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT03356808
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with stage III, stage IV, or relapsed lung cancer that has been confirmed by tissue biopsy.
  • People aged 18 to 80 years old.
  • People who have waited at least 4 weeks since their last chemotherapy or radiation treatment, and at least 2 weeks since last taking steroid or immune-suppressing medications.
  • People whose side effects from chemotherapy have cleared up.
  • People whose cancer cells have been tested and shown to have high levels of certain cancer-specific proteins (confirmed through lab testing of tissue samples).
  • People with a general health and ability-to-function score of at least 50% on a standard medical scale (confirm with trial site).
  • People with an expected survival of at least 6 weeks.
  • People with blood counts within acceptable ranges — enough white blood cells and platelets as measured by a blood test.
  • People with kidneys and liver functioning within acceptable ranges, based on blood tests.
  • People with an oxygen level in the blood of 90% or above.
  • People who have given written consent before any trial procedures begin.

Who may not be able to join:

  • People whose airway is blocked by a tumour.
  • People with a history of epilepsy or other brain or nervous system conditions.
  • People who currently need steroid medications or other immune-suppressing treatments.
  • People with a history of serious heart rhythm problems (specifically relating to a measurement called the QT interval — confirm with trial site).
  • People with a history of serious side effects from a drug called cyclophosphamide.
  • People who have taken part in another clinical drug trial or immune cell therapy study within the past 28 days.
  • People whose liver or kidney function test results fall outside the acceptable ranges set by the trial.
  • People who are pregnant or breastfeeding.
  • People who have a serious active infection at the time of screening.
  • People with active HIV, Hepatitis B, or Hepatitis C infection, or any other uncontrolled infection.
  • People who, in the opinion of the trial investigators, may not be suitable or may have difficulty following the trial requirements.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Lung-Ji Chang, PhD, Shenzhen Geno-Immune Medical Institute

Phone: +86 0755-86573763

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shenzhen Geno-Immune Medical Institute
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
31 December 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Safety of engineered T cells in patients using CTCAE version 4.0 standard to evaluate the level of adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov