Multiple Sclerosis Trial, Recruiting NCT03401879 Sponsor: Medical University of Vienna Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT03401879
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

For Healthy Volunteers:

Who might be able to join this trial:

  • Men and women who are 18 years of age or older
  • Non-smokers
  • People with generally normal results on a standard medical check-up (any minor issues would be assessed by the doctor)
  • People with normal eye health and no more than moderate prescription glasses or contact lenses (less than 6 Dpt)

Who may not be able to join:

  • People who have been told they may possibly have multiple sclerosis (MS)
  • People with a serious medical condition, as decided by the study doctor
  • People with high blood pressure that is not being treated
  • People who have a personal or family history of epilepsy
  • People with any eye problems that would make reliable eye measurements impossible, as decided by the study doctor
  • People with a family history of MS, optic neuritis, or a related condition called neuromyelitis optica (NMO or Devic disease)
  • People who have had an inflammatory or infectious disease affecting the brain or spinal cord
  • People whose best corrected vision (with glasses or contacts) is below a certain level
  • People with a strong glasses or contact lens prescription (6 Dpt or more)
  • People who are pregnant or planning to become pregnant
  • People with alcohol dependency or substance abuse issues

For Patients with MS:

Who might be able to join this trial:

  • Men and women who are 18 years of age or older
  • People who have been diagnosed with relapsing-remitting multiple sclerosis (a form of MS with flare-ups and recovery periods) based on recognised medical criteria
  • People who have had an episode of optic neuritis (inflammation of the eye nerve) in at least one eye, at least one year ago
  • Non-smokers
  • People with normal eye health and no more than a moderate glasses or contact lens prescription (less than 6 Dpt)
  • People with good enough vision to take part in the eye blood flow measurements used in this study
  • People whose other medications (not MS treatments) have been at a stable, unchanged dose for at least 30 days before joining, if the study doctor considers this relevant

Who may not be able to join:

  • People with a serious medical condition other than MS, as decided by the study doctor
  • People who have or have had neuromyelitis optica (NMO or Devic disease) or a related condition
  • People who have had an inflammatory or infectious disease affecting the brain or spinal cord, other than MS
  • People with high blood pressure that is not being treated
  • People who have a personal or family history of epilepsy
  • People with any eye problems that would make reliable eye measurements impossible, as decided by the study doctor
  • People whose best corrected vision (with glasses or contacts) is below a certain level
  • People with a strong glasses or contact lens prescription (6 Dpt or more)
  • People who are pregnant or planning to become pregnant
  • People with another significant neurological condition in addition to MS, if considered relevant by the study doctor
  • People with alcohol dependency or substance abuse issues

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Gerhard Garhöfer, MD, Department of Clinical Pharmacology, Medical University of Vienna

Phone: 0043140400

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 February 2018
Est. completion
1 March 2026

Where this trial is recruiting

🇦🇹 Austria

Primary endpoints

Flicker induced increase in retinal blood flow

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov